Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.12.7.2 (hydrogenase)
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Human Gene/Protein
selenophosphate synthase 10.8
NARF 10.8
HYD1 10.4
HYPC 10.3
H16 10.1
L-alanine:glyoxylate aminotransferase 10.0
ion transporter protein 10.0
integral membrane protein 2A 9.8
CALS 9.7
PSST subunit 9.6
IOP1 9.6
20-alpha-hydroxysteroid dehydrogenase 9.6
BBS 9.5
TYKY subunit 9.4
DC12 9.3
ISP2 9.3
succinyl coenzyme A synthetase 9.1
DRAL 9.1
CA11 9.0
FDH 8.9
TYKY 8.8
ferredoxin 8.8
DBP1 8.8
NCYM 8.7
ACSA 8.7
HUP1 8.6
MXD1 8.6
DHTKD1 8.6
glucose-6-phosphate 1-dehydrogenase 8.5
RNF 8.5
PSST 8.5
beta-ETF 8.1
Hos 8.1
TPAP 8.1
short-chain acyl-CoA dehydrogenase 8.1
Diaphorase 7.9
G20 7.9
cycA 7.9
DLST 7.9
NADH diaphorase 7.7
more...
Disease
Ogo 11.1
HYD2 10.1
FDH 7.8
Bardet-Biedl syndrome 7.7
adaptation reaction 7.3
Benson 7.2
Other variants 6.8
Hodgson 6.7
PCC 6.6
NBS 6.6
familial hemophagocytic lymphohistiocytosis 6.4
Photosensitization 6.0
VPI 5.9
BCD 5.3
pheochromocytoma 5.3
SME 5.1
emerging infectious disease 5.0
SRS 5.0
SCH 4.9
Diffuse idiopathic skeletal hyperostosis 4.8
CAA 4.8
Vogt 4.7
MBS 4.6
Frey 4.6
DMC 4.6
complicated pregnancy 4.5
NHC 4.5
PMS 4.5
Brucella suis 4.5
Lowe 4.5
trichomoniasis 4.4
CAA 4.4
HP1 4.2
DES 4.2
RHE 4.0
MTC 4.0
Bradley 3.9
MCD 3.9
anemia of chronic disease 3.8
primary hyperoxaluria 3.7
more...
Symptom
starvation 2.1
flushing 2.1
acidity 1.6
exertional dyspnea 1.4
tremor -0.0
agitation -0.4
exhaustion -0.6
collapse -0.7
diarrhea -1.1
vomiting -1.8
anesthesia -3.6
Drug
Ferric oxide 9.1
Flavin 7.3
NADH 6.1
Chlorate 6.0
DMAP 5.8
FAD 5.8
Ethane 5.4
Olmesartan 5.4
Sandostatin 4.9
Sandostatin 4.9
PCB 4.6
MTC 4.2
THF 4.2
Sinemet 4.1
Metrizamide 3.9
CPM 3.9
CoCl2 3.9
CoCl2 3.9
ZnCl2 3.8
ZnCl2 3.8
Glycerol 3.6
CIA 3.5
ascorbate 3.4
Fructose 3.2
MOF 3.2
L-tyrosine 2.9
Vitamin B12 2.9
Arsenic trioxide 2.8
FeCl3 2.7
ALA 2.7
NH3 2.7
Glycyrrhiza 2.7
Gel 2.6
MgSO4 2.6
Heme 2.5
TiO2 2.5
Itraconazole 2.2
-deoxyadenosine 2.1
ABC 2.0
lysine 2.0
more...
Enzyme
hydrogenase 13.1
hydrogenase maturation endopeptidase 13.1
hydrogenase 13.1
EC 1.12.2.1 13.1
bidirectional hydrogenase 13.1
membrane-bound hydrogenase 12.5
F420-reducing hydrogenase 12.1
methylenediurease 12.1
sulfur reductase 12.0
H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase 11.9
heterodisulfide reductase 11.6
methylenetetrahydromethanopterin dehydrogenase 11.0
methylviologen-reducing hydrogenase 10.8
sulfane sulfurtransferase 10.8
phloroglucinol reductase 10.8
pyruvate:ferredoxin oxidoreductase 10.7
CO dehydrogenase 10.7
EC 1.2.99.2 10.6
selenophosphate synthase 10.6
formate dehydrogenase 10.5
formate dehydrogenase 10.5
formate dehydrogenase 10.5
D-malate dehydrogenase 10.0
lactate racemase 9.9
formylmethanofuran dehydrogenase 9.6
butyrate kinase 9.6
butyryl-CoA dehydrogenase 9.5
decarbonylase 9.4
glutaconyl-CoA decarboxylase 9.1
opine dehydrogenase 9.1
hydroxylamine reductase 9.1
hydroxylamine reductase 9.1
nitrogenase 9.0
dissimilatory sulfite reductase 9.0
methyl coenzyme M reductase 8.9
nicotinic acid hydroxylase 8.9
malyl-CoA lyase 8.8
isobutyryl-CoA mutase 8.8
acetoacetate decarboxylase 8.7
KGOR 8.7
more...
Compound
2-Hydroxyphenazine 12.1
2-Hydroxyphenazine 12.1
Sirohydrochlorin 12.1
Benzyl Viologen 11.2
Coenzyme F420 10.9
C12H10O2 10.8
2,3-bis(bromomethyl)quinoxaline 10.6
1,4-dichloro-2-butyne 10.6
1,4-dichloro-2-butyne 10.6
H4MPT 10.4
6-aminonicotinic acid 10.1
6-aminonicotinic acid 10.1
Methanofuran 10.1
Curacin A 9.8
Tetrahydrocortisol 9.4
4-hydroxyphenyl acetate 9.4
Obacunone 9.3
Salicylaldoxime 9.1
2,4-DA 9.1
NPOH 9.1
Ferredoxin 8.9
1,2,3,4-tetrachlorobenzene 8.8
2-methyl-2-butenoic acid 8.7
CoM 8.7
Fe(CN)3 8.6
6-mercaptohexanoic acid 8.5
3-hydroxybutyryl-CoA 8.5
4-APP 8.4
Formate 8.4
malyl-CoA 8.3
DTMA 8.3
MBH 8.3
Fumarate 8.1
Plastoquinone 8.1
MPT 7.9
2-pyridinol 7.9
2-pyridinol 7.9
2-pyridinol 7.8
5-aminovalerate 7.8
butyryl-CoA 7.6
more...