Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:1.12.7.2 (hydrogenase)
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Human Gene/Protein
selenophosphate synthase 10.8
NARF 10.8
HYD1 10.4
HYPC 10.3
H16 10.1
ion transporter protein 10.0
L-alanine:glyoxylate aminotransferase 10.0
integral membrane protein 2A 9.8
CALS 9.7
PSST subunit 9.6
IOP1 9.6
20-alpha-hydroxysteroid dehydrogenase 9.6
BBS 9.5
TYKY subunit 9.4
DC12 9.3
ISP2 9.3
succinyl coenzyme A synthetase 9.1
DRAL 9.1
CA11 9.0
FDH 8.9
TYKY 8.8
ferredoxin 8.8
DBP1 8.8
NCYM 8.7
ACSA 8.7
HUP1 8.6
DHTKD1 8.6
MXD1 8.6
glucose-6-phosphate 1-dehydrogenase 8.5
PSST 8.5
RNF 8.5
beta-ETF 8.1
TPAP 8.1
Hos 8.1
short-chain acyl-CoA dehydrogenase 8.1
Diaphorase 7.9
G20 7.9
DLST 7.9
cycA 7.9
NADH diaphorase 7.7
HYPA 7.7
electron transfer flavoprotein-ubiquinone oxidoreductase 7.7
NifU 7.6
nrf 7.6
Chlamydomonas 7.6
SDH2 7.5
complex I) 7.5
Succinic semialdehyde dehydrogenase 7.5
Acetyl-CoA synthetase 7.4
cytochrome b561 7.4
acylphosphatase 7.4
K72 7.4
NMI 7.3
NeuroD2 7.3
Oxidoreductase 7.3
FMN 7.3
component D 7.3
oxidoreductase 7.2
ETF 7.2
ACAA 7.2
HP3 7.2
CA6 7.1
MR-1 7.1
DNA directed 7.0
TUTase 7.0
nicotinamide nucleotide transhydrogenase 7.0
EPR 7.0
FADH2 7.0
IscU 6.9
DG2 6.9
TR-1 6.9
C2H2 6.9
diaphorase 6.9
HADH 6.9
CALU 6.9
FHL-1 6.9
PCC 6.8
NADH: ubiquinone oxidoreductase 6.8
KH1 6.8
ECE 6.7
6-phosphogluconolactonase 6.7
acetyl-CoA synthetase 6.7
NADH dehydrogenase 6.6
IscS 6.5
14 kDa protein 6.5
acetaldehyde dehydrogenase 6.5
alanine-glyoxylate aminotransferase 6.5
fre 6.5
quinone oxidoreductase 6.5
Alcohol dehydrogenase 6.4
NADH-ubiquinone reductase 6.4
Zyxin 6.4
Hpr 6.4
NADP 6.4
NAD 6.4
H36 6.4
HM-1 6.4
RNA polymerase II subunit 6.3
decarboxylating 6.3
SHE 6.3
aconitate hydratase 6.3
AMHR2 6.2
RAR-beta 6.2
steroid hydroxylase 6.2
ORF4 6.2
A transferase 6.2
PN1 6.1
20 alpha-hydroxysteroid dehydrogenase 6.1
HSD-1 6.1
Cytochrome b 6.1
gamma, delta 6.1
NADH 6.1
S protein 6.1
FAF 6.1
succinate dehydrogenase subunit B 6.1
membrane-bound 6.0
cysteine desulfurase 6.0
soluble liver antigen 6.0
delta 4 6.0
CDD 6.0
H37 6.0
phosphatidylserine decarboxylase 6.0
D54 5.9
NRF 5.8
FMRFamide-related peptides 5.8
flavoprotein 5.8
SDHB 5.8
cytochrome 5.8
17 beta-hydroxysteroid dehydrogenase 5.8
Leu2 5.8
Pyruvate carboxylase 5.8
FAD 5.8
NADH2 5.7
steroid 5 alpha-reductase 5.7
19kDa 5.7
glycine-rich protein 5.7
FBPase 5.6
PFB 5.6
ATP synthase 5.6
Cyclophilin A 5.6
RNA polymerase subunit 5.6
cytochrome b 5.6
PML-RAR 5.6
EPG 5.5
NADP+ 5.5
NAD+ 5.5
peptidyl-prolyl cis-trans isomerase 5.4
TGC 5.4
TSD 5.4
succinic semialdehyde dehydrogenase 5.4
Ru2 5.4
endoprotease 5.4
Malate dehydrogenase 5.4
glyoxalase I 5.4
GSNOR 5.4
TRX 5.3
BCD 5.3
reductase 5.3
LDH-A 5.3
SME 5.3
more...
Disease
Ogo 11.1
HYD2 10.1
FDH 7.8
Bardet-Biedl syndrome 7.7
adaptation reaction 7.3
Benson 7.2
Other variants 6.8
Hodgson 6.7
PCC 6.6
NBS 6.6
familial hemophagocytic lymphohistiocytosis 6.4
Photosensitization 6.0
VPI 5.9
BCD 5.3
pheochromocytoma 5.3
SME 5.1
emerging infectious disease 5.0
SRS 5.0
SCH 4.9
Diffuse idiopathic skeletal hyperostosis 4.8
CAA 4.8
Vogt 4.7
MBS 4.6
Frey 4.6
DMC 4.6
complicated pregnancy 4.5
NHC 4.5
PMS 4.5
Brucella suis 4.5
Lowe 4.5
trichomoniasis 4.4
CAA 4.4
HP1 4.2
DES 4.2
RHE 4.0
MTC 4.0
Bradley 3.9
MCD 3.9
anemia of chronic disease 3.8
primary hyperoxaluria 3.7
RP4 3.7
APL 3.6
mole 3.5
APL 3.5
DIP 3.5
TCC 3.4
parakeratosis 3.4
NS2 3.4
HCI 3.4
SCS 3.3
pseudohypoparathyroidism 3.3
mole 3.3
Klebsiella 3.2
premenstrual syndrome 3.2
Proteus 3.1
conversion reaction 3.1
hereditary spherocytosis 3.0
bends 2.9
Dissociation 2.8
SDS 2.8
canker 2.8
chronic glomerulonephritis 2.7
APL 2.7
chemical carcinogenesis 2.7
CDS 2.7
Fox 2.6
typhoid 2.6
PGA 2.5
Tay-Sachs disease 2.5
hypernatremia 2.5
salmonellosis 2.4
hyperlipoproteinemia 2.4
Fibrillation 2.4
PAM 2.3
hypersensitivity pneumonitis 2.3
atherosclerotic cardiovascular disease 2.2
mimicry 2.2
Jensen 2.2
Giant 2.2
polyarteritis nodosa 2.2
NPC 2.1
meningoencephalitis 2.1
Q fever 2.0
chlorosis 2.0
ADH 2.0
Wiskott-Aldrich syndrome 2.0
Age-related macular degeneration 1.9
HSP 1.8
Merkel cell carcinoma 1.8
TOC 1.7
enteritis 1.7
rheumatism 1.7
tularemia 1.6
Shigella flexneri 1.6
Evans 1.6
drunk 1.5
ICP 1.4
lichen 1.4
medullary thyroid carcinoma 1.4
azoospermia 1.3
lymphoblastic leukemia 1.2
sudden infant death syndrome 1.2
neurofibromatosis type 1 1.2
toxic shock syndrome 1.1
ileus 1.0
appendicitis 1.0
Hippel 1.0
neurofibromatosis 0.9
CCD 0.9
gastritis 0.9
CCD 0.8
MAC 0.8
Barrett's esophagus 0.8
iron overload 0.6
Shigella 0.5
unstable angina 0.5
Mycobacterium 0.5
PDB 0.4
TEM 0.4
suicide 0.4
PCP 0.4
STD 0.4
iron deficiency 0.3
TEM 0.3
essential hypertension 0.3
hypercholesterolemia 0.3
acute promyelocytic leukemia 0.2
dehydration 0.2
Infections 0.1
peptic ulcer 0.1
mastitis 0.1
Echinococcus 0.1
Still 0.0
Blocking -0.0
glioblastoma multiforme -0.0
alcoholism -0.0
Yersinia -0.1
hyperglycemia -0.1
chronic hepatitis -0.1
cholera -0.2
vagina -0.2
cleft palate -0.2
hyperinsulinemia -0.2
NHS -0.3
ventricular hypertrophy -0.3
gastroenteritis -0.3
alcohol abuse -0.3
urinary tract infection -0.4
amyloidosis -0.4
periodontitis -0.5
acute renal failure -0.5
rare disease -0.5
NAME -0.6
dyslipidemia -0.6
fatty liver -0.6
hepatocellular carcinoma -0.7
malnutrition -0.7
hepatitis -0.7
ash -0.7
bacterial infection -0.8
more...
Symptom
starvation 2.1
flushing 2.1
acidity 1.6
exertional dyspnea 1.4
tremor -0.0
agitation -0.4
exhaustion -0.6
collapse -0.7
diarrhea -1.1
vomiting -1.8
anesthesia -3.6
Drug
Ferric oxide 9.1
Flavin 7.3
NADH 6.1
Chlorate 6.0
DMAP 5.8
FAD 5.8
Ethane 5.4
Olmesartan 5.4
Sandostatin 4.9
Sandostatin 4.9
PCB 4.6
MTC 4.2
THF 4.2
Sinemet 4.1
Metrizamide 3.9
CPM 3.9
CoCl2 3.9
CoCl2 3.9
ZnCl2 3.8
ZnCl2 3.8
Glycerol 3.6
CIA 3.5
ascorbate 3.4
Fructose 3.2
MOF 3.2
L-tyrosine 2.9
Vitamin B12 2.9
Arsenic trioxide 2.8
FeCl3 2.7
ALA 2.7
NH3 2.7
Glycyrrhiza 2.7
Gel 2.6
MgSO4 2.6
Heme 2.5
TiO2 2.5
Itraconazole 2.2
-deoxyadenosine 2.1
ABC 2.0
lysine 2.0
Fragment 2.0
TAT 1.9
Albumin 1.9
Glutathione 1.7
PCP 1.3
Ethanol 0.9
MAP 0.8
ROS 0.5
ZnO 0.4
DNase I 0.1
lactose 0.1
ampicillin 0.1
nitroglycerin 0.0
citric acid -0.1
Asn -0.4
Leaf -1.3
Enzyme
EC 1.12.2.1 13.1
hydrogenase 13.1
hydrogenase maturation endopeptidase 13.1
hydrogenase 13.1
bidirectional hydrogenase 13.1
membrane-bound hydrogenase 12.5
methylenediurease 12.1
F420-reducing hydrogenase 12.1
sulfur reductase 12.0
H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase 11.9
heterodisulfide reductase 11.6
methylenetetrahydromethanopterin dehydrogenase 11.0
methylviologen-reducing hydrogenase 10.8
phloroglucinol reductase 10.8
sulfane sulfurtransferase 10.8
pyruvate:ferredoxin oxidoreductase 10.7
CO dehydrogenase 10.7
EC 1.2.99.2 10.6
selenophosphate synthase 10.6
formate dehydrogenase 10.5
formate dehydrogenase 10.5
formate dehydrogenase 10.5
D-malate dehydrogenase 10.0
lactate racemase 9.9
formylmethanofuran dehydrogenase 9.6
butyrate kinase 9.6
butyryl-CoA dehydrogenase 9.5
decarbonylase 9.4
glutaconyl-CoA decarboxylase 9.1
hydroxylamine reductase 9.1
hydroxylamine reductase 9.1
opine dehydrogenase 9.1
nitrogenase 9.0
dissimilatory sulfite reductase 9.0
methyl coenzyme M reductase 8.9
nicotinic acid hydroxylase 8.9
malyl-CoA lyase 8.8
isobutyryl-CoA mutase 8.8
acetoacetate decarboxylase 8.7
KGOR 8.7
acetate kinase 8.6
fumarate reductase 8.6
superoxide reductase 8.5
glycine reductase 8.5
dihydroxyacetone kinase 8.5
acetylene hydratase 8.4
methylglyoxal synthase 8.4
pyruvate formate-lyase 8.4
cellodextrin phosphorylase 8.4
chlorate reductase 8.3
sulfite reductase 8.2
sulfite reductase 8.2
A-transferase 8.2
1,3-propanediol dehydrogenase 8.2
sulfite reductase 8.2
rubredoxin reductase 8.2
benzoyl-CoA reductase 8.1
enoate reductase 8.0
homocitrate synthase 8.0
coproporphyrinogen III oxidase 8.0
TSR 8.0
MT 1 7.9
phosphotransbutyrylase 7.7
glycerol dehydratase 7.5
biotin synthase 7.5
desulfhydrase 7.5
lysine 2,3-aminomutase 7.4
TUT 7.4
APS reductase 7.4
3-hydroxybutyryl-CoA dehydrogenase 7.4
ferredoxin reductase 7.4
glycolate dehydrogenase 7.3
acylphosphatase 7.3
isopropylmalate isomerase 7.2
cellobiose phosphorylase 7.2
succinic dehydrogenase 7.2
bilirubin oxidase 7.1
acetyl-CoA synthetase 6.9
glycerol dehydrogenase 6.9
EC 4.4.1.5 6.9
glycerol dehydrogenase 6.9
trimethylamine dehydrogenase 6.8
6-phosphogluconolactonase 6.7
nitrous oxide reductase 6.6
nitrate reductase 6.6
nitrate reductase 6.6
nitrate reductase 6.6
nitrate reductase 6.6
nitrate reductase 6.6
nitrate reductase 6.5
NADH dehydrogenase 6.5
leucine dehydrogenase 6.5
phospholipid methyltransferase 6.5
urease 6.5
thermitase 6.5
transhydrogenase 6.5
urease 6.5
succinyl-CoA synthetase 6.5
hydroxylamine oxidoreductase 6.5
glucose permease 6.4
NAD+ oxidoreductase 6.4
diaphorase 6.4
diaphorase 6.3
nicotinamide mononucleotide adenylyltransferase 6.2
NADH peroxidase 6.1
tripeptidase 6.1
signal peptidase II 6.1
nitrite reductase 6.1
nitrite reductase 6.1
alanine dehydrogenase 6.1
EC 3.6.1.1 6.0
flavanone 3-hydroxylase 6.0
methanol dehydrogenase 6.0
NADPH-diaphorase 6.0
nitrite reductase 6.0
anthocyanidin synthase 6.0
flavonol synthase 6.0
complex I 6.0
IscS 6.0
LipA 5.9
methane monooxygenase 5.8
rubisco 5.8
ATP sulfurylase 5.7
3alpha-hydroxysteroid dehydrogenase 5.6
triose-phosphate isomerase 5.6
PTA 5.6
peptidyl-prolyl cis-trans isomerase 5.5
phosphatidylserine decarboxylase 5.5
cinnamate 4-hydroxylase 5.5
EC 1.1.1.40 5.5
NQO1 5.4
PCE 5.4
pyruvate dehydrogenase 5.4
cyclohydrolase 5.4
pyruvate dehydrogenase 5.4
haloalkane dehalogenase 5.3
E-2 5.3
TOR 5.2
SCS 5.2
glucose dehydrogenase 5.1
acyl-CoA dehydrogenase 5.1
histidine kinase 5.1
methylamine dehydrogenase 5.1
pyruvate oxidase 5.1
pyruvate dehydrogenase 5.0
citrate lyase 5.0
ATP synthase 5.0
fumarase 5.0
chalcone isomerase 5.0
dihydroorotase 5.0
alcohol dehydrogenase 5.0
aconitase 5.0
adrenodoxin reductase 4.9
succinic semialdehyde dehydrogenase 4.9
VOR 4.8
4CL 4.8
orotate phosphoribosyltransferase 4.8
disulfide reductase 4.7
ALA synthase 4.7
restriction-modification system 4.7
more...
Compound
Sirohydrochlorin 12.1
2-Hydroxyphenazine 12.1
2-Hydroxyphenazine 12.1
Benzyl Viologen 11.2
Coenzyme F420 10.9
C12H10O2 10.8
2,3-bis(bromomethyl)quinoxaline 10.6
1,4-dichloro-2-butyne 10.6
1,4-dichloro-2-butyne 10.6
H4MPT 10.4
6-aminonicotinic acid 10.1
6-aminonicotinic acid 10.1
Methanofuran 10.1
Curacin A 9.8
Tetrahydrocortisol 9.4
4-hydroxyphenyl acetate 9.4
Obacunone 9.3
NPOH 9.1
2,4-DA 9.1
Salicylaldoxime 9.1
Ferredoxin 8.9
1,2,3,4-tetrachlorobenzene 8.8
2-methyl-2-butenoic acid 8.7
CoM 8.7
Fe(CN)3 8.6
6-mercaptohexanoic acid 8.5
3-hydroxybutyryl-CoA 8.5
4-APP 8.4
Formate 8.4
DTMA 8.3
malyl-CoA 8.3
MBH 8.3
Fumarate 8.1
Plastoquinone 8.1
MPT 7.9
2-pyridinol 7.9
2-pyridinol 7.9
2-pyridinol 7.8
5-aminovalerate 7.8
butyryl-CoA 7.6
Helenalin 7.6
diphenylsilane 7.4
diphenylsilane 7.4
1,2,3-trichlorobenzene 7.4
3,4-dihydroisoquinoline 7.4
1-phenyl-1,2-ethanediol 7.3
G20 7.3
Mesna 7.2
C2H2 7.1
nickel 6.9
FMN 6.9
Flavin 6.9
pentadecane 6.8
XTP 6.8
DCMU 6.8
NiCl2 6.7
1,2-dithiolane 6.7
heptyl 6.6
heptyl 6.6
2-methyl-2,4-pentanediol 6.5
corrin 6.5
BTL 6.5
Copper sulfate 6.4
NAD 6.4
2-oxoadipate 6.4
SDZ PSC 833 6.3
2-butenal 6.3
NADP 6.3
Glycolate 6.3
cholan-24-oic acid 6.3
2,3-dihydrofuran 6.3
Chlorate 6.2
NAD 6.2
cholan-24-oic acid 6.2
Selenocysteine 6.2
NADH 6.1
Farnesyl diphosphate 6.1
1,2-dichloropropane 6.1
Menaquinone 6.0
MoO4 6.0
hydrogen 5.9
Na2S 5.9
DMAP 5.9
2-aminoethanol 5.9
cyanide 5.9
Ferricyanide 5.8
2,3-butanediol 5.8
2,3-butanediol 5.8
2,3-butanediol 5.8
Chlorate 5.8
phenazine 5.8
DCB 5.8
Sodium bisulfite 5.7
FAD 5.7
DCB 5.7
Pyruvate 5.7
KIV 5.7
Azobenzene 5.7
DCC 5.7
Paraquat 5.6
heptadecane 5.6
carbamyl phosphate 5.6
DCB 5.6
BF4 5.5
BF4 5.5
BF4 5.5
Mr 30 5.5
Pyrogallol 5.5
iron 5.5
dibenzyl 5.4
Ribulose 5.4
PCE 5.4
TMPD 5.4
Glyoxylate 5.4
1,3-propanediol 5.3
PRD 5.3
Plumbagin 5.3
DCB 5.3
Trimethylamine 5.3
CH3-THF 5.3
2-phenylpyridine 5.3
Cys-Gly 5.2
3-hydroxy-2-butanone 5.2
PCE 5.2
Antimycin 5.2
Hypo 5.2
6-phosphogluconate 5.1
DCB 5.1
acetyl-CoA 5.1
Chlorophyll a 5.1
CO2 5.1
Rhein 5.1
mercaptoacetic acid 5.0
molybdenum 5.0
Cystathionine 5.0
PCMB 5.0
PCMB 5.0
PCMB 5.0
p-cresol 5.0
Cystathionine 5.0
PCMB 4.9
PDT 4.9
1,4-diazabicyclo[2.2.2]octane 4.9
1,4,8,11-tetraazacyclotetradecane 4.9
butanal 4.9
H2S 4.9
methane 4.8
FMNH 4.8
NADPH 4.8
NADPH 4.8
HSO 4.7
adenosylmethionine 4.7
CAA 4.7
heptanal 4.7
ubiquinol 4.7
heptanal 4.7
trifluoromethanesulfonic acid 4.7
H2S 4.7
alcohol dehydrogenase 4.7
heptanal 4.7
more...