Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.12.7.2 (hydrogenase)
 3,522 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Chronic alcohol intoxication results in the diminished testosterone level and activation of lipid peroxidation in rat testes. A significant decrease in 3 beta-hydroxysteroid-hydrogenase and 17-dehydrogenase activity has been observed in microsomes. Analogous shifts have been evoked in vitro by the induction of lipid peroxidation in microsomes. That permitted one to suppose that alcohol-induced alterations in tests are partially mediated by induction of lipid peroxidation.
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PMID:[Influence of ethanol and ethanol-induced lipid peroxidation on the steroidogenic activity of testicles]. 823 38