Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.11.1.9 (
glutathione peroxidase
)
22,002
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
glutathione peroxidase
21462
superoxide dismutase
12055
catalase
10549
GSH
6616
glutathione reductase
4259
antioxidant enzyme
1935
Sep
1485
glutathione S-transferase
1456
Mol
1252
SOD
1057
lactate dehydrogenase
953
aspartate aminotransferase
898
caspase-3
795
TNF
762
tumor necrosis factor
746
alkaline phosphatase
637
alanine aminotransferase
627
glucose-6-phosphate dehydrogenase
625
insulin
615
peroxidase
599
Bcl-2
462
Superoxide dismutase
453
Catalase
426
MnSOD
423
NADPH
423
xanthine oxidase
392
IL-6
389
inducible nitric oxide synthase
380
ROS
371
heme oxygenase-1
368
myeloperoxidase
364
albumin
351
hemoglobin
351
acetylcholinesterase
348
erythroid
347
glutathione transferase
343
GST
339
reductase
339
thioredoxin reductase
321
CAT
315
manganese superoxide dismutase
309
Nrf2
302
Glutathione peroxidase
301
glutathione peroxidase 1
292
interleukin-6
291
creatine kinase
284
microsomal
259
ATPase
257
ATP
257
cytokine
255
nitric oxide synthase
253
GSR
233
lipopolysaccharide
229
selenoprotein
228
p53
220
thioredoxin
217
collagen
197
cytochrome P450
193
carp
193
metallothionein
193
SOD1
189
lysozyme
184
AST
176
ceruloplasmin
176
HSP70
176
spermatozoa
169
p65
166
erythrocyte glutathione peroxidase
165
cytochrome c
159
p38
157
cyclooxygenase-2
154
cytochrome
142
selenoprotein P
141
SOD2
140
caspase-9
138
HDL
138
gamma-glutamyl transpeptidase
135
NAD
135
gut
134
IL-10
132
more...
Disease
GSH
6616
cancer
1038
diabetes
942
tumor
600
ischemia
570
carcinogenesis
347
Alzheimer's disease
336
atherosclerosis
266
hypertension
241
hyperglycemia
241
Parkinson's disease
204
obesity
179
depression
168
cardiovascular disease
164
myocardial infarction
153
type 2 diabetes
151
hepatocellular carcinoma
141
cerebral ischemia
141
breast cancer
137
stroke
136
cold
131
carcinoma
124
epididymis
111
cognitive impairment
107
memory impairment
103
hyperlipidemia
101
myocardial ischemia
98
heart failure
94
anemia
93
cataract
93
MCF
90
cardiomyopathy
89
B-cell lymphoma
87
NAME
85
rheumatoid arthritis
82
fatty liver
81
Pineal
80
liver disease
77
leukemia
76
arthritis
76
dementia
75
renal disease
75
diabetic nephropathy
73
hypercholesterolemia
72
malnutrition
71
proteinuria
71
sepsis
70
neuroblastoma
68
chronic renal failure
66
sepsis
66
SDS
66
lung cancer
65
Selenium deficiency
65
cirrhosis
62
tumorigenesis
61
colon cancer
60
adenocarcinoma
58
schizophrenia
58
epilepsy
58
coronary heart disease
57
HIV
57
tumor growth
57
asthma
56
infertility
54
metabolic syndrome
53
pheochromocytoma
53
iron overload
53
Down syndrome
52
prostate cancer
49
liver fibrosis
49
melanoma
49
hyperthyroidism
49
renal failure
48
lymphoma
48
AIN
47
dyslipidemia
47
vitamin E deficiency
47
worms
46
preeclampsia
46
colitis
45
more...
Symptom
hyperoxia
162
seizures
83
anesthesia
73
pain
70
fatigue
62
exhaustion
44
diarrhea
41
starvation
37
collapse
26
overweight
24
weakness
24
functional recovery
21
hypothermia
20
respiratory distress
18
skin damage
18
anorexia
16
acute stress
16
angina
14
acidity
14
memory loss
13
headache
11
Decreased activity
11
ataxia
10
tremor
10
nausea
9
erythema
8
hypercapnia
8
hypotonia
7
insomnia
6
cachexia
6
splenomegaly
6
cough
5
Anoxia
5
hepatomegaly
5
vomiting
5
stigma
5
thinning
5
lethargy
5
despair
4
dyspnea
4
arthralgia
4
emaciation
4
dry eye
4
chills
4
tinnitus
4
abdominal pain
4
neurological pain
3
Ill
3
colic
3
bradykinesia
3
HSA
3
nausea and vomiting
3
myalgia
3
ophthalmoplegia
3
polydipsia
3
twitching
3
flushing
3
shortness of breath
2
cyanosis
2
menopausal symptoms
2
dizziness
2
sleepiness
2
hypoproteinemia
2
polyuria
2
discomfort
2
hyperemesis gravidarum
2
wheezing
2
discomfort
2
incoordination
2
inanition
2
chest pain
2
spasm
2
abnormal gait
2
blurred vision
2
constipation
2
Diaphragmatic weakness
1
chronic cough
1
pallor
1
skin irritant
1
dysarthria
1
more...
Drug
vitamin E
1210
ascorbate
888
Glutathione
398
ROS
371
Vitamin E
189
Ethanol
103
NADH
99
Cardiovasc
73
Dermatol
61
lysine
53
IL-2
51
Adriamycin
51
CTX
50
ALA
38
Monit
37
Indomethacin
31
Nephron
29
Gel
28
Nephron
27
Leaf
27
caffeine
25
Vitamin A
25
Heme
21
Rutin
21
MAP
21
CTX
20
ZnO
20
CTX
20
Arsenic trioxide
19
EE2
19
FAD
18
citric acid
18
TAC
17
PCB
17
Albumin
16
Ginseng
16
EPA
16
TiO2
15
Angiotensin II
15
Aloe
14
IFN-gamma
14
lactose
14
Bifidobacterium
14
Mutagen
14
nitroglycerin
12
Epigallocatechin
12
Fluorescein
11
Glycyrrhiza
11
Nitric Oxide
10
MRC
10
niacin
10
CSF
10
Tocopherol
10
Alanine
9
Acacia
9
Ginger
9
Captopril
9
Fipronil
9
Asn
8
Propofol
8
HCH
8
Monensin
8
CCL
8
pyridoxal phosphate
8
CoCl2
8
CoCl2
8
Serum albumin
7
Olive oil
7
Lead acetate
7
ZnCl2
7
Portal
7
Vitamin K
7
Docetaxel
7
ROC
7
Simvastatin
7
ZnCl2
7
Asthma
7
ATV
6
ETS
6
Parkin
6
more...
Enzyme
glutathione peroxidase
22002
superoxide dismutase
12498
catalase
10585
glutathione reductase
4353
glutathione S-transferase
1962
aspartate aminotransferase
1054
alanine aminotransferase
1045
peroxidase
1000
lactate dehydrogenase
986
glucose-6-phosphate dehydrogenase
711
alkaline phosphatase
637
caspase-3
626
xanthine oxidase
390
acetylcholinesterase
376
creatine kinase
362
thioredoxin reductase
321
mitogen-activated protein kinase
314
gamma-glutamyl transpeptidase
281
ATPase
273
NQO1
255
NADPH oxidase
209
ceruloplasmin
186
ascorbate peroxidase
186
lysozyme
184
NADPH oxidase
178
AST
176
peroxiredoxin
175
gamma-glutamylcysteine synthetase
170
heme oxygenase
150
acid phosphatase
126
phospholipid hydroperoxide glutathione peroxidase
125
protein kinase
123
caspase-9
109
ERK
96
NO synthase
95
lipoxygenase
94
complex I
89
dehydroascorbate reductase
87
succinate dehydrogenase
83
lipase
80
protein kinase C
78
phospholipase A2
71
isocitrate dehydrogenase
67
cholinesterase
65
paraoxonase
64
paraoxonase
62
diaphorase
61
citrate synthase
60
isocitrate dehydrogenase
59
monoamine oxidase
58
SOR
57
6-phosphogluconate dehydrogenase
55
glutathione synthetase
55
6-phosphogluconate dehydrogenase
55
ECH
54
hexokinase
53
AMP-activated protein kinase
52
trypsin
51
CPR
50
ACE
49
PARP
49
P-glycoprotein
46
tyrosine hydroxylase
45
pyruvate kinase
43
cytochrome oxidase
42
glyceraldehyde-3-phosphate dehydrogenase
42
ornithine decarboxylase
42
delta-aminolevulinic acid dehydratase
42
aldose reductase
41
disulfide reductase
39
aldehyde dehydrogenase
39
glucose oxidase
39
NOS
39
demethylase
37
UDP-glucuronosyltransferase
37
caspase-8
36
malate dehydrogenase
36
glyceraldehyde-3-phosphate dehydrogenase
35
aldehyde dehydrogenase
34
glyceraldehyde-3-phosphate dehydrogenase
34
more...
Compound
GSH
6877
GSH
6877
oxygen
4645
selenium
2872
water
1713
DNA
1608
Dec
1598
hydrogen
1591
glucose
1262
nitric oxide
1166
H2O2
1103
sodium
1043
GSSG
926
copper
776
TNF
762
zinc
743
Clin
710
creatinine
693
urea
634
iron
633
MDA
548
nitrogen
541
ethanol
524
cysteine
494
NADPH
425
NADPH
424
calcium
418
cadmium
415
acetate
357
CAT
315
CAT
315
CAT
315
Malondialdehyde
290
phosphate
286
ATP
257
galactose
256
manganese
248
glutamate
245
methionine
226
N-acetylcysteine
223
Vitamin E
216
Melatonin
204
arginine
195
sulfate
188
MTT
188
8-OHdG
181
mercury
177
superoxide radical
175
CCl4
172
alanine
171
alloxan
154
nitrate
152
NAD
148
salt
142
potassium
135
NAD
135
Ascorbic acid
134
1-chloro-2,4-dinitrobenzene
134
nicotinamide
125
Adriamycin
117
chromium
112
bromide
111
DPPH
110
methanol
107
tert-butyl hydroperoxide
102
Curcumin
102
iodine
99
STZ
99
NADH
99
anthracene
98
pyrene
95
aldehyde
95
DDP
95
retinol
94
homocysteine
94
ADP
91
ammonia
91
APAP
90
ADP
83
gallic acid
83
more...