Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.10.3.3 (ascorbate oxidase)
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Human Gene/Protein
DCLK3 12.7
SRF1 12.3
alpha 4(IV) collagen 12.2
G-protein coupled receptor-associated sorting protein 1 11.7
NADK 11.6
SRG1 11.2
PPA2 11.1
Lec35 10.6
FYB 10.3
cytochrome b561 10.2
ZIP13 10.1
Hephaestin 9.9
BST1 9.8
cytochrome b-561 9.8
ATP synthase subunit beta 9.8
CTNND2 9.8
Polyamine oxidase 9.7
dek 9.6
VDP 9.4
D-amino acid oxidase 9.4
mannose phosphate isomerase 9.3
ARF7 9.3
DCIP 9.3
myo-inositol oxygenase 9.2
BRK 9.2
DDO 9.1
HADH 9.1
BPR 9.1
alpha-amidating monooxygenase 8.9
ABG 8.8
PFK-1 8.8
NAD kinase 8.8
GOX 8.7
K84 8.6
ferroxidase 8.6
Rho GTPase-activating protein 8.5
HB2 8.4
ceruloplasmin 8.3
D-amino-acid oxidase 8.3
ARF4 8.3
tre 8.2
BAF155 8.2
SSF 8.2
PTA 8.1
AO2 8.1
Ceruloplasmin 8.1
hephaestin 8.1
SVCT2 8.1
FMT 8.1
CISS 8.0
MOX 7.9
HB1 7.9
ACO 7.9
SGT1 7.9
TEK 7.8
extracellular superoxide dismutase 7.8
sarcosine oxidase 7.8
DAR 7.8
ATP13A2 7.7
IL7 7.7
dopamine beta-hydroxylase 7.7
CCL14 7.6
NADH-ubiquinone reductase 7.6
RNO 7.5
AOX 7.5
aminoacylase 7.4
apolipoprotein C-II 7.3
phosphomannose isomerase 7.3
D-serine 7.3
ELS 7.2
MOG 7.2
6-phosphofructokinase 7.2
serine racemase 7.1
glyoxalase II 7.1
CAO 7.1
ABR 7.1
diamine oxidase 7.0
pyrroline-5-carboxylate synthetase 7.0
survival-related 7.0
partial protein 7.0
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Disease
Lermoyez's syndrome 11.6
Salzmann 9.6
AO2 9.4
acute suppurative otitis media 9.2
Meniere's disease 9.2
ear disease 8.1
Rhinosinusitis 7.8
endolymphatic hydrops 7.8
Facial palsy 7.7
aminoaciduria 7.6
PARK7 7.3
RSI 7.3
Copper deficiency 7.0
vestibular neuritis 6.9
labyrinthitis 6.7
Middle ear 6.6
Buerger's disease 6.5
FPP 6.4
HHS 6.4
HHS 6.4
PARK2 6.3
chronic suppurative otitis media 6.2
MCD 6.1
KNO 6.0
cholesteatoma 6.0
Darier's disease 5.9
otosclerosis 5.9
PMS 5.7
CHARGE syndrome 5.6
schwannoma 5.5
middle ear effusion 5.3
overbite 5.3
Bell's palsy 5.3
Menkes 5.3
otitis externa 5.3
PAL 5.2
tattoo 5.2
acoustic neuroma 5.1
Sweet 5.0
sensorineural hearing loss 4.9
facial palsy 4.9
Hereditary angioedema 4.9
otitis 4.7
hypovitaminosis 4.6
middle ear 4.6
scotoma 4.5
premenstrual syndrome 4.4
LCA 4.4
Nelson 4.3
GSH 4.3
Wiskott-Aldrich syndrome 4.2
acute otitis media 4.2
pH increased 4.1
nystagmus 4.0
HSP 4.0
NF2 4.0
spongiform encephalopathy 4.0
TOC 3.9
Fabry 3.9
mitral valve prolapse 3.8
sinusitis 3.8
otitis media 3.6
progressive supranuclear palsy 3.6
TCP 3.5
aqueous humor 3.4
erythroleukemia 3.3
benign tumor 3.2
PCA 3.1
MAS 3.1
CCD 3.1
primary hyperparathyroidism 3.1
herpes zoster 3.0
illusion 3.0
sleep disturbances 2.9
arteriosclerosis 2.9
mimicry 2.8
ARF 2.8
neuroticism 2.6
basal cell carcinoma 2.6
macular degeneration 2.5
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Symptom
facial droop 8.3
vertigo 7.8
hyperacusis 6.8
tinnitus 6.6
ENT 4.9
abdominal discomfort 4.6
paresis 3.8
hoarseness 3.8
dizziness 3.7
tremor 2.2
anesthesia 0.2
weakness 0.1
headache -0.5
seizures -1.0
pain -1.1
Drug
Ts-1 10.8
Arial 10.8
Tween 85 9.2
Gallium nitrate 9.0
ascorbate 8.4
Xanthan gum 8.1
Diamox 8.0
Rasburicase 7.3
RSM 6.9
Methylene blue 6.0
DMSA 5.8
FAD 5.7
Galactose 5.3
NADH 5.2
ETS 5.0
FeCl3 4.9
MgSO4 4.7
VCR 4.7
HCH 4.6
ENT 4.3
NAG 4.2
Capsicum 4.2
L-tyrosine 4.1
Gel 4.0
Glutathione 3.9
Vitamin E 3.6
NH3 3.5
TiO2 3.4
citric acid 3.1
Leaf 2.9
vitamin E 2.8
Asn 2.8
SiO2 2.8
ZnO 2.6
ROC 2.4
Biopolymers 2.3
ABC 2.2
lysine 1.8
MAP 1.4
lactose 1.3
ROS 1.1
Asthma 0.7
Enzyme
ascorbate oxidase 15.3
aryl-aldehyde oxidase 15.3
D-2-hydroxy acid dehydrogenase 12.3
EC 1.3.2.3 11.7
lysine 2-monooxygenase 11.6
homoglutathione synthetase 11.5
gamma-tocopherol methyltransferase 11.0
glutathione oxidase 11.0
aryl-alcohol oxidase 10.4
vanillyl-alcohol oxidase 10.3
AO1 10.2
dehydroascorbate reductase 10.1
putrescine oxidase 10.1
myo-inositol oxygenase 10.0
NAD+ kinase 9.9
bilirubin oxidase 9.9
D-aspartate oxidase 9.8
SOR 9.7
glycerol-3-phosphate oxidase 9.6
creatininase 9.5
creatinase 9.4
NCED 9.1
uricase 9.0
laccase 8.7
AFR 8.7
hydroxylamine oxidoreductase 8.6
choline oxidase 8.6
oxalate oxidase 8.4
ascorbate peroxidase 8.4
catechol oxidase 8.2
dopamine beta-hydroxylase 8.2
ceruloplasmin 8.2
D-amino-acid oxidase 8.1
sarcosine oxidase 7.9
phytochelatin synthase 7.9
violaxanthin de-epoxidase 7.8
lactate oxidase 7.8
PTA 7.8
betaine aldehyde dehydrogenase 7.7
galactose oxidase 7.6
phenol oxidase 7.6
nitrite reductase 7.5
nitrite reductase 7.4
nitrite reductase 7.4
pectin methylesterase 7.4
glyoxalase II 7.4
NADH-cytochrome b5 reductase 7.3
methylamine dehydrogenase 7.2
serine racemase 7.1
proline dehydrogenase 7.0
tyrosinase 7.0
ACC oxidase 6.9
phosphomannose isomerase 6.8
glycolate oxidase 6.8
aldehyde oxidase 6.8
nitrous oxide reductase 6.8
alcohol oxidase 6.8
catechol 2,3-dioxygenase 6.8
lysine decarboxylase 6.7
diamine oxidase 6.6
glutamate dehydrogenase 6.5
sulfite oxidase 6.5
lignin peroxidase 6.5
acylase 6.5
polyamine oxidase 6.5
sulfite oxidase 6.4
lysyl endopeptidase 6.4
bromelain 6.3
CDH 6.2
prolyl hydroxylase 6.1
cysteine synthase 6.0
glutathione reductase 6.0
cholesterol oxidase 5.9
transhydrogenase 5.9
gamma-glutamylcysteine synthetase 5.8
glycerol kinase 5.8
rhodanese 5.8
glucose oxidase 5.7
GABA transaminase 5.7
peroxidase 5.5
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Compound
HNS 13.9
Yellow AB 13.7
3,5-dichloro-2-hydroxybenzenesulfonic acid 13.0
4-allylphenol 12.3
p-Hydroxymandelic acid 12.3
C9H11NO2 11.7
2,5-dimethylphenol 10.9
Rebeccamycin 10.8
Dehydroascorbic acid 10.7
A-500 10.7
MoS4 10.5
threonate 10.4
Brassinolide 10.0
Brassinolide 10.0
3,4-dihydroxybenzaldehyde 10.0
3,4-dihydroxybenzaldehyde 9.6
2-NP 9.4
DCIP 9.3
Betahistine 9.2
Ascorbic acid 9.0
Mimosine 9.0
2-NP 9.0
Mimosine 8.9
D-Serine 8.8
MTU 8.8
S-phenyl 8.6
uroporphyrin I 8.6
Potassium permanganate 8.6
S-phenyl 8.6
OPDA 8.4
AT-101 8.3
AT-101 8.2
AT-101 8.2
MnO4 8.2
GDP-D-mannose 8.2
Ferricyanide 8.0
DHB 7.8
2-methyl-2,4-pentanediol 7.7
keto-gamma 7.7
Amytal 7.6
Silver, 7.6
3-hydroxybenzoic acid 7.6
TMPD 7.6
Amax 7.5
Anthocyanin 7.3
S-benzyl 7.2
mercaptoacetic acid 7.2
Tocopherols 7.2
Sodium azide 6.9
EPC 6.9
DBH 6.9
mercaptoacetic acid 6.7
BSO 6.7
MCE 6.7
Pyrroloquinoline quinone 6.7
PTU 6.7
PPO 6.7
4-methoxybenzyl 6.7
Ribulose 6.6
DDC 6.6
DDC 6.6
beta-Carotene 6.5
His-Leu 6.5
DHBA 6.3
Arsenate 6.3
VMA 6.3
3-hydroxybutyric acid 6.2
DHBA 6.2
p-cresol 6.1
ECS 6.1
NMP 6.1
alpha-Tocopherol 6.1
PTU 6.1
Hemin 6.0
Hemin 6.0
Hemin 6.0
Hemin 6.0
Tempol 6.0
CDH 6.0
Cytochrome c 6.0
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