Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.10.3.2 (
laccase
)
4,656
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The effect of concentration of ethanol and dimethyl sulfoxide on the catalytic activity of
laccase
is studied for the enzymatic reaction of catechol oxidation and bioelectrocatalytic reaction of oxygen reduction under the conditions of direct electron transfer. Laccase-Nafion composite is elaborated ensuring the enzyme stability in a wide potential range and a content of organic solvents. Based on the
STM
measurements, the structure of composite layer is proposed. It is shown that the mechanism of oxygen reduction reaction by
laccase
in organo-aqueous mixtures is similar to that earlier proposed for aqueous solutions. A decrease in the electrocatalytic activity of
laccase
in the oxygen reduction correlates with a decrease in the
laccase
enzymatic activity in the substrate oxidation. However, a decrease in the
laccase
activity in the composite is observed at a higher content of organic solvent in the mixture. The mechanism of
laccase
inactivation by organic solvents is proposed.
...
PMID:Peculiarities of direct bioelectrocatalysis by laccase in aqueous-nonaqueous mixtures. 1239 43
