Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.10.3.2 (
laccase
)
4,656
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The culture of Streptomyces galbus
ISP
-5089 has a yellow-green colour caused by the accumulation of actinomycin X when it is grown in synthetic media at 28 degrees C; the colour turns dark-brown at 42 degrees C due to the synthesis of melanoid pigments. The population composition does not undergo any noticeable changes in that case, an no specific melanin-synthesizing mutants appear as a result of autoselection . The biosynthesis of actinomycin X (at 28 degrees C) and melanoid pigments (at 42 degrees C) is regulated by temperature. At 42 degrees C, L-DOPA oxidase is synthesized and
laccase
is activated; these two enzymes are involved in the synthesis of melanoid pigments. The organism does not has tyrosinase. The synthesis of melanoid pigments, when the mesophilic culture of S. galbus
ISP
-5089 is grown in the regime of superoptimal temperatures (42 to 47 degrees C), may be considered as a protective ecological reaction of the organism to unfavourable conditions of the environment.
...
PMID:[Nature of the brown pigment and the composition of the phenol oxidases of Streptomyces galbus]. 620 87
