Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.10.3.1 (tyrosinase)
9,065 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
tyrosinase 7452
Tyrosinase 762
peroxidase 647
Sep 606
Mol 451
microphthalmia-associated transcription factor 401
catalase 352
tyrosinase-related protein-1 309
gp100 257
superoxide dismutase 248
NMR 236
MSH 227
TRP-2 195
MART-1 190
glucosidase 184
beta-endorphin 176
TRP-1 166
tyrosinase-related protein 1 162
MITF 162
Melan-A 132
amylase 126
acetylcholinesterase 126
tyrosine hydroxylase 120
SDS 119
F10 113
endoplasmic reticulum 109
dopachrome tautomerase 109
GSH 102
HLA 101
p38 97
HLA-A2 87
PPO 85
TYR 79
CD8 78
extracellular signal-regulated kinase 73
ESI 72
butyrylcholinesterase 72
lipoxygenase 67
Pseudomonas 65
polypeptide 65
FRAP 64
glycoprotein 63
ERK 62
chitinase 62
MAGE 59
AMP 58
DCF 58
tyrosinase-related protein-2 57
alkaline phosphatase 56
EPR 56
collagen 55
agouti 55
cytokine 54
TRP1 53
reductase 52
MEL 50
CREB 50
xanthine oxidase 49
membrane-bound 49
oxidoreductase 49
MAPK 48
MAGE-3 47
acid phosphatase 47
TRP2 47
serum albumin 46
S100 46
tyrosinase-related protein 2 46
NADH 45
P protein 45
lipase 44
GABA(A) receptor 44
SOD 43
collagenase 41
p53 40
melanocortin 1 receptor 39
ACTH 38
stem cell factor 38
MHC 37
glutathione reductase 37
fused 37
more...
Disease
melanoma 2145
cancer 566
tumor 506
Melanoma 212
vitiligo 170
metastatic melanoma 122
metastases 122
SDS 119
GSH 102
melasma 91
Parkinson's disease 72
skin cancer 65
cold 65
mole 63
ATN 55
amelanotic melanoma 48
suicide 46
freckles 44
mole 43
cutaneous melanoma 38
Hermansky-Pudlak syndrome 37
Alzheimer's disease 37
diabetes 36
leukoderma 35
influenza 34
tumor growth 33
leukemia 33
cholera 32
lentigo 31
tumor progression 29
SEM 28
carcinoma 27
stage IV melanoma 26
infestation 26
carcinogenesis 25
melanosis 21
neuroblastoma 21
CAP 20
MCF 20
breast cancer 19
skin disease 19
PAL 18
cytomegalovirus 18
obesity 18
nystagmus 18
Waardenburg syndrome 17
tumorigenesis 17
dermatitis 17
primary tumor 16
autoimmune disease 16
vaccinia 16
dehydration 16
herpes simplex 15
sarcoma 14
TEM 13
Brown 13
TEM 13
acne 13
Steroids 12
lymphoma 12
PDB 12
OCA3 12
deafness 12
prostate cancer 12
uveal melanoma 11
depression 11
Menkes 11
infectious diseases 11
DBA 11
hepatocellular carcinoma 11
Mycobacterium 11
Klebsiella 11
CHS 10
angiomyolipoma 10
hypertension 10
ash 10
glaucoma 9
lichen 9
type 2 diabetes 9
Harada 9
more...
Symptom
acidity 32
erythema 17
skin irritation 15
skin damage 12
pain 10
nausea 8
collapse 8
starvation 7
thinning 7
chills 6
photophobia 6
vomiting 6
agitation 6
diarrhea 5
exhaustion 5
tremor 4
DNA marker 3
anesthesia 3
Spots 3
HSA 3
Hudson 2
cough 2
dyspnea 2
weakness 2
ataxia 2
fasciculation 2
lethargy 1
Decreased activity 1
Lightening 1
myalgia 1
cachexia 1
dystonia 1
analgesia 1
pallor 1
emaciation 1
paresis 1
skin irritant 1
ENT 1
memory loss 1
fatigue 1
stigma 1
Overlying 1
microbial colonization 1
functional recovery 1
hypotonia 1
physical appearance 1
flushing 1
dental pain 1
insomnia 1
headache 1
menometrorrhagia 1
anorexia 1
ACHE 1
Drug
Dermatol 537
L-tyrosine 236
ascorbate 94
NADH 47
citric acid 41
lysine 40
IFN-gamma 35
ROS 34
Leaf 27
IL-2 23
vitamin E 19
CSF 18
Glycyrrhiza 18
caffeine 14
ZnO 14
Glutathione 13
Asn 13
Aloe 12
Retinoic acid 12
Gel 10
lactose 8
DNase I 8
CaCl2 7
MAP 7
CaCl2 7
Capsicum 7
CaCl2 7
Sesamol 6
EE2 6
G418 6
Ethanol 5
Bifidobacterium 5
BH4 5
TiO2 5
ENT 5
ampicillin 5
CAM 5
Monit 4
THF 4
Spectrum 4
p75 4
MRC 4
MOF 4
Ginseng 4
Theophylline 4
Fraction 4
3,4-Dihydroxyphenylalanine 4
nitroglycerin 3
Captopril 3
ETA 3
Histamine 3
CCL 3
CTC 3
Premarin 3
Latanoprost 3
Gly-Tyr-Gly 3
Etoposide 3
NBT 2
Forskolin 2
Angiotensin II 2
Portal 2
Hyaluronidase 2
ISP 2
Senna 2
KAN 2
Scopolamine 2
Sinemet 2
Biopolymers 2
Swertia 2
Xanthium 2
Silica 2
Azithromycin 2
Tannic acid 2
Viagra 2
PCB 2
Viagra 2
Zmax 2
Spectrum 2
Trifluoperazine 2
Vitamin B 2
more...
Enzyme
tyrosinase 9065
peroxidase 693
DCF 499
phenol oxidase 466
catalase 362
superoxide dismutase 274
laccase 214
mitogen-activated protein kinase 190
acetylcholinesterase 167
protein kinase 144
catechol oxidase 137
cholinesterase 118
tyrosine hydroxylase 116
PAL 109
ERK 104
ascorbate peroxidase 80
trypsin 74
urease 68
urease 68
lipoxygenase 67
elastase 66
chitinase 62
reverse transcriptase 62
alkaline phosphatase 60
collagenase 56
protein kinase C 52
acid phosphatase 50
proteasome 47
xanthine oxidase 45
invertase 44
lipase 44
cellulase 43
glucose oxidase 40
glutathione reductase 39
MEK 38
ceruloplasmin 36
luciferase 34
lignin peroxidase 31
ascorbate oxidase 29
glutathione peroxidase 28
hyaluronidase 28
hyaluronidase 28
pectin methylesterase 26
ATPase 25
ACS 23
beta-galactosidase 23
glutathione S-transferase 22
adenylate cyclase 21
NQO1 20
transglutaminase 19
chymotrypsin 19
RNA polymerase 19
phenylalanine hydroxylase 19
aryl-alcohol oxidase 19
pectinase 19
PAL 18
xylanase 18
xylanase 18
azoreductase 17
phosphodiesterase 16
gamma-glutamyl transpeptidase 16
transcriptase 16
lactate dehydrogenase 16
caspase-3 14
beta-glucosidase 14
beta-glucuronidase 14
nitrate reductase 13
nitrate reductase 13
nitrate reductase 13
nitrate reductase 13
nitrate reductase 13
nitrate reductase 13
ACE 13
cytochrome oxidase 12
phosphatidylinositol 3-kinase 12
carbonic anhydrase 12
alcohol dehydrogenase 12
monoamine oxidase 12
shikimate dehydrogenase 11
sucrase 11
more...
Compound
tyrosine 822
Dec 725
copper 680
water 608
oxygen 574
L-DOPA 562
DNA 481
phenol 384
hydrogen 290
DPPH 236
sodium 225
methanol 221
Phe 210
Melanin 200
cysteine 191
ethanol 185
cAMP 180
Dopa 169
ethyl acetate 143
phosphate 143
hydroquinone 127
His 127
galactose 126
SDS 121
nitrogen 118
ammonia 115
sulfate 110
3,4-dihydroxyphenylalanine 110
GSH 109
GSH 109
Clin 99
iron 98
acetate 97
glucose 97
gallic acid 94
H2O2 89
alpha-MSH 87
PPO 85
ammonium 79
salt 78
zinc 77
alanine 73
calcium 73
Cu(II) 70
proline 67
tryptophan 65
nitric oxide 65
MTT 64
leucine 63
salicylic acid 62
arginine 61
AMP 59
bromide 59
lysine 58
silver 58
benzoic acid 51
methionine 50
resorcinol 50
thiourea 49
hexane 47
Catechol 47
acetic acid 46
acetone 46
NADH 46
Kojic acid 45
tryptophan 45
tryptophan 44
tryptophan 44
urea 44
Gly 43
kaempferol 43
DAD 42
Ascorbic acid 42
p-cresol 41
chloroform 41
potassium 39
PEG 38
serine 38
retinoic acid 37
benzene 37
more...