Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.10.3.1 (tyrosinase)
 9,065 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

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Human Gene/Protein
cAMP-dependent protein kinase type II-alpha regulatory subunit 11.8
two pore segment channel 2 11.8
tyrosinase related protein-2 11.8
tyrosinase precursor 11.8
RNA binding motif protein 9 11.8
SNRP116 11.8
cAMP-dependent protein kinase catalytic subunit gamma 11.8
tyrosinase 11.7
Tyrosinase 11.4
TRP-1 11.4
TRP-2 11.3
tyrosinase-related protein-1 11.2
tyrosinase-like 11.1
tyrosinase-related protein 1 11.1
tyrosinase-related protein-2 11.0
TYRP2 10.9
dopachrome tautomerase 10.9
integral membrane transporter protein 10.8
MELPH 10.8
cAMP-dependent protein kinase type II-beta regulatory subunit 10.8
TFECL 10.8
microphthalmia-associated transcription factor 10.7
microphtalmia-associated transcription factor 10.6
Tyrosinase-related protein 1 10.5
Hermansky-Pudlak syndrome type 1 10.5
Tyrosinase-related protein-2 10.5
MITF protein 10.3
oculocutaneous albinism II 10.3
TRP2 10.3
collagen type V alpha 1 10.2
NAALADase II 10.2
TYRL 10.2
WS2A 10.2
TCRAV2S1 10.2
DDCT 10.2
tyrosinase-related protein 2 10.2
Paired box 3 10.0
gp100 9.9
TYRP1 protein 9.9
ANKRD27 9.8
homeobox D9 9.8
collagen XXI 9.8
MART1 9.7
MART-1 9.7
MAGE-3 9.6
CSNK1G3 9.5
SLC12A7 9.5
XPA binding protein 1 9.5
TYRP1 9.5
OS-9 protein 9.5
PAPOLB 9.5
SILV 9.4
TYR 9.4
MITF 9.3
RAB32 9.3
Melan-A 9.2
DCIP 9.2
MITF-C 9.2
rd5 9.2
TRP1 9.2
MATP 9.0
Mitf 9.0
ASMTL 9.0
helix-loop-helix zipper protein 9.0
BAGE 8.9
PIG1 8.8
melanocortin 1 receptor 8.8
MAGE1 8.8
PCPE 8.8
MAGE-2 8.7
RUTBC1 8.6
HLA-B*4403 8.6
CAPN6 8.6
Adapter protein 8.6
Tissue-specific extinguisher 1 8.6
MNT 8.6
MSH receptor 8.5
HPS5 8.5
paired box 3 8.5
HPS3 8.5
MAGE3 8.5
frizzled 6 8.5
hedgehog acyltransferase 8.5
CAS2 8.5
TPCN2 8.5
MAGE2 8.5
SNRPD1 8.5
RAGE-1 8.5
transcription factor binding to IGHM enhancer 3 8.5
melanoma antigen MART-1 8.4
GALM 8.3
Putative transcription factor 8.3
SLC9A7 8.3
HLAA 8.3
MSH 8.3
HCNP 8.2
ETR-1 8.2
PAPG 8.2
PRKACG 8.2
msg1 8.2
SLC24A4 8.1
4a-carbinolamine dehydratase 8.1
Hermansky-Pudlak syndrome 8.0
DCF 8.0
melanoma antigen 8.0
APH-1B 8.0
PPO 7.9
HPS1 7.9
melastatin 1 7.9
EVI2B 7.9
PAX-3 7.9
melanophilin 7.9
GSX2 7.9
MAGE-C2 7.8
Transcriptional regulator 7.8
toll-like receptor 1 7.8
MAGE 7.7
transcription factor EC 7.7
MLPH 7.7
Low-density lipoprotein receptor-related protein 6 7.7
hemoglobin beta chain 7.7
tyrosine kinase pp60c-src 7.7
plexin C1 7.7
VIT1 7.7
DCT 7.6
MUM-1 7.6
Myosin-X 7.6
MSH4 7.6
ASIP 7.6
MYO5A 7.5
STAM-1 7.5
HEM45 7.5
MC1R 7.5
KRT6C 7.5
Ubiquitin carboxyl-terminal hydrolase 7.5
histone H1.3 7.5
melanoma inhibitory activity 7.5
F10 7.4
sPLA2-X 7.4
LAMP-3 7.4
SY11 7.4
signal protein 7.4
OA1 7.4
melanoma-associated antigen 7.4
HPS6 7.3
CDO1 7.3
transient receptor potential canonical 1 7.3
TPP2 7.3
p600 7.3
histamine receptor H1 7.3
EXOC2 7.3
DCoH 7.3
PEP1 7.2
PDEB 7.2
CIB2 7.2
RAB38 7.2
MIXL1 7.2
collagen type I alpha 2 7.2
P protein 7.2
KIS 7.1
more...
Disease
WS2-OA 11.8
Oculocutaneous albinoidism 11.8
OCA1B 11.2
OCA3 10.9
Pigmentary incontinence 10.2
OCA4 10.0
Cervical Carcinoma 9.8
ROCA 9.5
Postinflammatory hypopigmentation 9.5
Cross syndrome 9.3
TSC3 9.2
melasma 9.0
melanoderma 8.9
freckles 8.8
Spindle cell melanoma 8.8
Premature graying 8.8
Generalized vitiligo 8.7
leukoderma 8.5
X-linked ocular albinism 8.4
canities 8.4
amelanotic melanoma 8.2
Riehl's melanosis 8.2
ATN 8.1
Mixed tumor 8.0
stage IV melanoma 7.9
Bonnier 7.8
Segmental vitiligo 7.7
Erythema dyschromicum perstans 7.7
EA3 7.5
vitiligo 7.4
Hermansky-Pudlak syndrome 7.2
lentigo 7.0
junctional nevus 7.0
HFH 7.0
stage II melanoma 7.0
Vogt-Koyanagi 6.9
WS4 6.8
dyschromia 6.8
melanoma 6.8
Waardenburg syndrome 6.6
Melanoma 6.6
melanoma stage 6.4
Triton tumor 6.4
Metastatic malignant melanoma 6.4
melanosis coli 6.3
multiple nevi 6.3
stage I melanoma 6.3
melanosis 6.2
Polymorphic light eruption 6.2
metastatic melanoma 6.1
ochronosis 6.0
nRNA 6.0
Lentigo maligna 6.0
stage III melanoma 6.0
WS1 5.9
PAL 5.8
Biotin deficiency 5.8
recurrent melanoma 5.7
ARP1 5.6
Civatte 5.6
SAMS 5.6
Bergeron 5.6
Fusarium infection 5.5
Fowlpox 5.5
Becker's nevus 5.5
Enzyme inhibition 5.4
compound nevus 5.4
PBT 5.4
Gliosarcoma 5.4
PEComa 5.3
HHP 5.3
Harada 5.3
benign nevi 5.2
Atypical fibroxanthoma 5.2
evaluable disease 5.2
Menkes 5.2
cutaneous melanoma 5.2
rind 5.2
Irritant contact dermatitis 5.1
CBS deficiency 5.1
Burnett 5.1
poliosis 5.1
blue nevus 5.0
WS2 5.0
Desmoplastic 5.0
NNH 5.0
dermatofibrosarcoma 4.9
melanoma in situ 4.9
urticaria pigmentosa 4.9
CHS 4.9
CAE 4.8
X-linked retinoschisis 4.8
Clear cell sarcoma 4.8
CAE 4.8
uveal melanoma 4.6
poison ivy 4.6
Griscelli syndrome 4.5
CNS metastases 4.5
Herlitz 4.5
uvea 4.5
CLE 4.5
CAP 4.5
dysplastic nevi 4.4
CLE 4.4
Phototoxicity 4.3
Hodgson 4.3
lens opacity 4.3
OCM 4.3
angiomyolipoma 4.3
hypomelanosis of Ito 4.3
BCH 4.2
trichotillomania 4.2
Dedifferentiation 4.2
skin cancer 4.2
photoallergy 4.1
AIDS/HIV 4.1
HTX 4.0
HTX 4.0
MSF 4.0
hemorrhagic diathesis 4.0
PPB 4.0
Ototoxicity 3.9
Shigella boydii 3.9
HBB 3.8
HBB 3.8
HBB 3.8
squamous cell carcinoma of the skin 3.8
color blindness 3.8
Degos 3.8
CPX 3.8
avian leukosis 3.8
ear infection 3.8
Werdnig-Hoffmann disease 3.7
plant disease 3.7
OAR 3.7
high-grade lymphomas 3.7
CNF 3.7
PME 3.7
SCA2 3.6
MVA 3.6
AOS 3.6
Horner's syndrome 3.6
prurigo 3.6
poikiloderma 3.5
Sentinel node 3.5
tyrosinemia 3.5
pityriasis versicolor 3.5
Sweet 3.5
DIA 3.5
mite infestation 3.5
Horner syndrome 3.5
MNS 3.4
myeloblastosis 3.4
infectious hepatitis 3.4
Goldblatt 3.4
xanthogranuloma 3.4
mole 3.4
Vogt 3.3
gliosarcoma 3.3
MCS 3.3
more...
Symptom
Lightening 8.2
Overlying 5.3
skin damage 4.8
skin irritation 4.6
Spots 4.5
menometrorrhagia 4.5
skin irritant 4.2
ACHE 3.9
photophobia 3.7
DNA marker 3.5
acidity 2.9
Hudson 2.7
Decreased activity 2.7
fasciculation 2.4
chills 2.3
erythema 2.2
HSA 1.8
emaciation 1.7
microbial colonization 1.7
dental pain 1.5
physical appearance 1.2
thinning 1.1
agitation 0.8
pallor 0.5
exhaustion 0.4
nausea 0.3
starvation -0.0
collapse -0.0
memory loss -0.0
tremor -0.4
ENT -0.6
vomiting -0.6
cachexia -0.7
lethargy -0.7
paresis -0.7
hypotonia -0.7
flushing -0.9
myalgia -0.9
ataxia -1.2
dystonia -1.3
insomnia -1.6
diarrhea -1.7
cough -1.8
stigma -1.9
functional recovery -1.9
anorexia -2.0
dyspnea -2.0
weakness -2.4
pain -2.9
analgesia -3.0
anesthesia -3.4
fatigue -3.9
headache -4.0
Drug
Skinoren 9.5
Cysteine hydrochloride 8.8
Angelica dahurica root 8.6
Axokine 8.6
Tinosorb S 8.5
L-tyrosine 8.4
Uvinul 8.3
Gly-Tyr-Gly 8.0
Equilenin 7.6
Phosphomycin 7.5
Sesamol 7.5
3,4-Dihydroxyphenylalanine 7.5
Aescin 6.7
Hoelen 6.4
Ephedrae Herba 6.4
Voglibose 6.4
Sodium metabisulfite 6.3
Ozagrel 6.3
Bethanidine 6.1
DOXY 6.1
Latanoprost 6.1
Sodium ascorbate 6.0
PBZ 6.0
Pancreatin 6.0
Sulla 5.8
Violaxanthin 5.8
KAN 5.6
Peppermint 5.5
Ciglitazone 5.5
Glycyrrhiza 5.5
Carbidopa 5.4
Zinc sulfate 5.2
Zinc sulfate 5.2
Azacytidine 5.2
Ddc 5.2
Aloe 5.1
Premarin 5.1
Clove 5.1
Compound 16 5.1
Perphenazine 5.1
Ethylenediamine 5.0
CMX 5.0
Cinnarizine 5.0
Red ginseng 4.9
Swertia 4.9
Compound 9 4.8
Zmax 4.7
Palmitoyl 4.6
Xanthan gum 4.6
FLM 4.5
ROX 4.5
Senna 4.5
Methyldopa 4.5
Senna 4.4
Malachite Green 4.3
Bentonite 4.3
Tannic acid 4.2
Camphor 4.2
Camphor 4.1
Estriol 4.0
Trifluoperazine 4.0
Epigallocatechin 4.0
Hyaluronidase 4.0
Viagra 3.9
Ammonium chloride 3.9
ISP 3.9
citric acid 3.9
Loratadine 3.9
ascorbate 3.8
Crystal Violet 3.8
Hyaluronidase 3.8
Rasburicase 3.8
Asparaginase 3.8
Propidium 3.8
Cobalamin 3.7
Sinemet 3.7
Areca 3.7
Papain 3.7
Retinoic acid 3.6
Zein 3.6
Viagra 3.6
BH4 3.5
Capsicum 3.4
Rutin 3.4
Auranofin 3.4
TRM 3.2
G418 3.2
Etoposide 3.2
SPP 3.2
Retinoic Acid 3.2
Ginseng 3.1
Glutathione 3.1
Xanthium 3.1
CTC 3.0
CCL 3.0
Finasteride 3.0
MEA 3.0
Moxifloxacin 2.9
NADH 2.9
Emodin 2.9
Ginger 2.9
KGF 2.9
Dermatol 2.8
Theophylline 2.8
Omeprazole 2.8
Glutamic acid 2.8
Dihydro 2.7
CTC 2.7
Clofibrate 2.6
ROS 2.6
Emodin 2.6
linolenate 2.6
Dasatinib 2.5
Azithromycin 2.5
Digenea 2.5
Digitalis 2.5
Vitamin B 2.5
R1881 2.5
Glide 2.5
Pilocarpine 2.4
Fraction 2.4
Scopolamine 2.4
NBT 2.4
Tocopherol 2.3
Carotenoid 2.3
MOF 2.2
Captopril 2.2
Coral 2.2
Leaf 2.1
IFN-gamma 2.1
MRC 2.0
Gelatin 2.0
Asn 2.0
CaCl2 2.0
CaCl2 2.0
vitamin E 1.9
ETA 1.9
CaCl2 1.9
p75 1.9
ZnO 1.8
DNase I 1.8
Galactose 1.8
NAG 1.7
DHT 1.7
Hypaque 1.7
DHT 1.6
CAM 1.6
Bifidobacterium 1.6
CEC 1.6
Silica 1.6
RFP 1.5
Hypaque 1.5
Serum albumin 1.5
Vitamin B12 1.5
pyridoxal phosphate 1.5
IL-2 1.5
DPA 1.5
EE2 1.4
Pronase 1.4
Forskolin 1.4
more...
Enzyme
tyrosinase 11.8
catechol oxidase 11.8
aureusidin synthase 11.2
phenol oxidase 10.9
GriF 10.8
2-methylisocitrate dehydratase 10.8
quercetin 3-O-methyltransferase 10.2
DCF 9.8
dihydrobenzophenanthridine oxidase 9.5
pterin-4alpha-carbinolamine dehydratase 9.2
aryl-alcohol oxidase 9.1
geraniol dehydrogenase 9.0
shikimate dehydrogenase 8.0
hexose oxidase 7.9
p-hydroxyphenylacetate 3-hydroxylase 7.7
PAL 7.5
glutathione oxidase 7.5
azoreductase 7.4
laccase 7.3
ascorbate oxidase 7.0
pectin methylesterase 7.0
lignin peroxidase 6.9
AAE 6.9
clavaminate synthase 6.8
cyanide hydratase 6.7
12-oxophytodienoate reductase 6.6
ascorbate peroxidase 6.6
histidase 6.5
NAD+ kinase 6.4
beta-agarase 6.4
caffeoyl-CoA O-methyltransferase 6.4
endomannosidase 6.4
ent-kaurene oxidase 6.4
polysaccharide deacetylase 6.3
oxalate oxidase 6.2
salicylate hydroxylase 6.1
N-acetylglucosaminyltransferase V 6.1
neopullulanase 6.0
FTR 6.0
CPA2 5.9
homogentisate 1,2-dioxygenase 5.8
tyrosine decarboxylase 5.8
chitin deacetylase 5.7
chitinase 5.7
retinal dehydrogenase 5.7
phenylalanine hydroxylase 5.6
EC 4.4.1.5 5.5
isoflavone reductase 5.5
NADPH:quinone oxidoreductase 5.5
anthocyanidin reductase 5.5
bilirubin oxidase 5.4
tyrosine phenol-lyase 5.3
tannase 5.3
PAL 5.3
isovaleryl-CoA dehydrogenase 5.2
peroxidase 5.2
chalcone isomerase 5.2
Lod 5.2
prephenate dehydrogenase 5.2
leucine dehydrogenase 5.1
cinnamate 4-hydroxylase 5.1
glucose dehydrogenase 5.1
uracil phosphoribosyltransferase 5.1
sucrose phosphorylase 5.1
stilbene synthase 5.1
porphobilinogen deaminase 5.0
urease 5.0
cytokinin oxidase/dehydrogenase 5.0
4CL 5.0
cholinesterase 5.0
gamma-glutamyl kinase 5.0
amylosucrase 5.0
urease 5.0
manganese peroxidase 5.0
invertase 5.0
glutamic dehydrogenase 5.0
beta-1,3-glucanase 4.9
chitosanase 4.9
stilbene synthase 4.9
prephenate dehydrogenase 4.9
sulfhydryl oxidase 4.9
cytosine deaminase 4.8
lysyl oxidase 4.8
alcohol oxidase 4.8
tyrosine hydroxylase 4.8
pectinase 4.8
lipoxygenase 4.8
hatching enzyme 4.8
beta-xylosidase 4.7
glucose oxidase 4.7
beta-1,3-glucanase 4.7
flavanone 3-hydroxylase 4.7
elastase 4.7
isochorismate synthase 4.6
diol dehydratase 4.6
ceruloplasmin 4.6
glycine decarboxylase 4.6
protocatechuate 3,4-dioxygenase 4.6
flavonol synthase 4.6
catalase 4.5
cysteine conjugate beta-lyase 4.5
cellulase 4.5
mannitol dehydrogenase 4.5
cutinase 4.4
methane monooxygenase 4.4
hyaluronidase 4.4
ubiquinol-cytochrome c oxidoreductase 4.4
acetylcholinesterase 4.4
violaxanthin de-epoxidase 4.3
SOR 4.3
dehydroascorbate reductase 4.3
sepiapterin reductase 4.3
PME 4.3
glucosidase II 4.3
mannitol dehydrogenase 4.2
xanthine oxidase 4.2
lactate oxidase 4.2
cellobiohydrolase 4.2
catechol O-methyltransferase 4.2
lysine decarboxylase 4.1
amylomaltase 4.1
acetylesterase 4.1
aspartase 4.1
superoxide dismutase 4.0
chalcone synthase 4.0
cyclohydrolase 4.0
sucrase 4.0
CEP 4.0
hyaluronidase 4.0
cysteine dioxygenase 4.0
4-hydroxyphenylpyruvate dioxygenase 4.0
CO dehydrogenase 4.0
BMA 4.0
cholesterol oxidase 3.9
inositol 3-kinase 3.9
dopamine beta-hydroxylase 3.9
beta-glucosidase 3.9
xylanase 3.9
glucosylceramide synthase 3.9
formaldehyde dehydrogenase 3.9
glutathione reductase 3.8
xylanase 3.8
aldehyde oxidase 3.8
alpha-mannosidase 3.8
transglutaminase 3.8
acid phosphatase 3.8
TGT 3.8
ADH3 3.8
aromatic L-amino acid decarboxylase 3.7
alanine dehydrogenase 3.7
S-adenosyl-L-homocysteine hydrolase 3.7
thioredoxin reductase 3.7
galactose oxidase 3.7
proline oxidase 3.7
beta-glucosidase 3.6
nitrate reductase 3.6
nitrate reductase 3.6
gamma-glutamylcysteine synthetase 3.6
nitrate reductase 3.6
nitrate reductase 3.6
more...
Compound
Swertiajaponin 11.8
C17H24O4 11.8
C17H24O4 11.8
4-chlorobenzaldehyde thiosemicarbazone 11.8
C17H24O4 11.8
C17H24O4 11.8
C17H24O4 11.8
phenyl 4-methylbenzenesulfonate 11.8
C17H24O4 11.8
Blue RX 11.8
Tokoronin 11.8
C9H9NO7 11.8
C17H24O4 11.8
4,4-dimethylchromane 11.8
C17H24O4 11.8
Aureusidin 11.4
C19H17NO4 10.8
C15H12O2 10.8
C18H26O4 10.8
C19H17NO4 10.8
C10H10ClNO2 10.8
C10H10ClNO2 10.8
C10H10ClNO2 10.8
N-hydroxy-N'-phenylthiourea 10.8
C19H17NO4 10.8
C19H17NO4 10.8
C19H14O 10.8
C19H17NO4 10.8
C19H17NO4 10.8
C10H10ClNO2 10.8
C19H17NO4 10.8
C18H26O4 10.8
C18H26O4 10.8
C18H26O4 10.8
C19H17NO4 10.8
C10H10ClNO2 10.8
gamma-Fagarine 10.8
methyl 2-amino-3-phenylpropanoate 10.8
C19H17NO4 10.8
C10H10ClNO2 10.8
C19H17NO4 10.8
C10H10ClNO2 10.8
Haginin A 10.8
C18H26O4 10.8
C16H12O4 10.8
Ethyl p-methoxycinnamate 10.8
C10H10ClNO2 10.8
C19H17NO4 10.8
methyl 2-amino-3-phenylpropanoate 10.8
C19H17NO4 10.8
C15H12O2 10.8
C19H17NO4 10.8
C15H12O2 10.8
C10H8N2O 10.8
C19H17NO4 10.8
C19H17NO4 10.8
C10H10ClNO2 10.8
C15H12O2 10.8
C18H26O4 10.8
C19H17NO4 10.8
C10H10ClNO2 10.8
C10H10ClNO2 10.8
2,4-dihydroxy-N-(2-hydroxyethyl)benzamide 10.8
C19H17NO4 10.8
C19H17NO4 10.8
DHICA 10.7
L-dopachrome 10.6
cyclodopa 10.5
1-bromoheptane 10.4
Kojic acid 10.3
Aloesin 10.3
C8H9NO3 10.2
C18H24O3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9N3OS 10.2
C8H9NO3 10.2
C19H17NO4 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C19H17NO4 10.2
Caffeoyl quinic acid 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
Astringin 10.2
C8H9NO3 10.2
2,4-dihydroxyphenylalanine 10.2
C8H16O2 10.2
C15H24N2 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
4-Ethylresorcinol 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
vinyl hexanoate 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C18H26O4 10.2
C8H9NO3 10.2
Maclurin 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C21H15N3O2 10.2
C8H9NO3 10.2
C17H22O5 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C19H17NO4 10.2
C8H9NO3 10.2
Pilosine 10.2
C19H17NO4 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C19H17NO4 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
DOPA sulfate 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
C8H9NO3 10.2
Dopaquinone 9.9
4-ethoxyphenol 9.9
4-methoxybenzonitrile 9.8
Cardol 9.8
Rutacridone epoxide 9.8
ML-236A 9.8
Diasone 9.8
C8H9NO3 9.8
C8H9NO3 9.8
more...