Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.10.3.1 (tyrosinase)
 9,065 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
tyrosinase 7452
Tyrosinase 762
peroxidase 647
Sep 606
Mol 451
microphthalmia-associated transcription factor 401
catalase 352
tyrosinase-related protein-1 309
gp100 257
superoxide dismutase 248
NMR 236
MSH 227
TRP-2 195
MART-1 190
glucosidase 184
beta-endorphin 176
TRP-1 166
tyrosinase-related protein 1 162
MITF 162
Melan-A 132
acetylcholinesterase 126
amylase 126
tyrosine hydroxylase 120
SDS 119
F10 113
dopachrome tautomerase 109
endoplasmic reticulum 109
GSH 102
HLA 101
p38 97
HLA-A2 87
PPO 85
TYR 79
CD8 78
extracellular signal-regulated kinase 73
ESI 72
butyrylcholinesterase 72
lipoxygenase 67
Pseudomonas 65
polypeptide 65
FRAP 64
glycoprotein 63
ERK 62
chitinase 62
MAGE 59
AMP 58
DCF 58
tyrosinase-related protein-2 57
alkaline phosphatase 56
EPR 56
collagen 55
agouti 55
cytokine 54
TRP1 53
reductase 52
MEL 50
CREB 50
oxidoreductase 49
membrane-bound 49
xanthine oxidase 49
MAPK 48
acid phosphatase 47
TRP2 47
MAGE-3 47
tyrosinase-related protein 2 46
S100 46
serum albumin 46
NADH 45
P protein 45
lipase 44
GABA(A) receptor 44
SOD 43
collagenase 41
p53 40
melanocortin 1 receptor 39
ACTH 38
stem cell factor 38
CD4 37
MHC 37
fused 37
glutathione reductase 37
proteasome 36
Mitf 36
ceruloplasmin 36
MHC class I 35
ERK1 35
melanoma antigen 35
TOF 35
IFN-gamma 35
AKT 35
TYRP1 35
ROS 34
MEK 32
Hermansky-Pudlak syndrome 31
antioxidant enzyme 31
IFN 30
lipopolysaccharide 30
c-kit 29
membrane protein 29
MC1R 29
catenin 29
dimeric 29
hyaluronidase 28
microsomal 28
AChE 28
Gen 27
endothelin-1 27
MITF protein 27
esterase 27
KIT 27
glutathione peroxidase 27
p38 mitogen-activated protein kinase 26
calnexin 25
ATPase 24
ATP 24
phosphatase 24
vimentin 23
glucosamine 23
IL-2 23
ACS 23
MART1 23
caspase-3 23
tyrosinase-like 22
Catalase 22
mitogen-activated protein 22
DCIP 22
DCT 21
CD34 21
NY-ESO-1 21
lectin 21
1A1 21
HLA class I 21
CAP 20
major histocompatibility complex 20
NADPH 20
adenylate cyclase 20
PKA 20
granulocyte-macrophage colony-stimulating factor 20
PI3K 20
tumor necrosis factor 20
proteasome inhibitor 19
MSH receptor 19
MNT 19
PEG 19
insulin 19
cAMP response element-binding protein 19
melanoma-associated antigen 19
PKC 19
albumin 18
prenylated 18
BRAF 18
hairless 18
IL-6 18
PAL 18
phenylalanine hydroxylase 18
transglutaminase 18
TCR 18
basic helix-loop-helix 17
DT-diaphorase 17
interleukin-2 17
more...
Disease
melanoma 2145
cancer 566
tumor 506
Melanoma 212
vitiligo 170
metastases 122
metastatic melanoma 122
SDS 119
GSH 102
melasma 91
Parkinson's disease 72
cold 65
skin cancer 65
mole 63
ATN 55
amelanotic melanoma 48
suicide 46
freckles 44
mole 43
cutaneous melanoma 38
Alzheimer's disease 37
Hermansky-Pudlak syndrome 37
diabetes 36
leukoderma 35
influenza 34
tumor growth 33
leukemia 33
cholera 32
lentigo 31
tumor progression 29
SEM 28
carcinoma 27
infestation 26
stage IV melanoma 26
carcinogenesis 25
melanosis 21
neuroblastoma 21
CAP 20
MCF 20
breast cancer 19
skin disease 19
nystagmus 18
PAL 18
obesity 18
cytomegalovirus 18
Waardenburg syndrome 17
dermatitis 17
tumorigenesis 17
vaccinia 16
primary tumor 16
dehydration 16
autoimmune disease 16
herpes simplex 15
sarcoma 14
TEM 13
acne 13
TEM 13
Brown 13
lymphoma 12
OCA3 12
prostate cancer 12
deafness 12
PDB 12
Steroids 12
hepatocellular carcinoma 11
depression 11
uveal melanoma 11
Mycobacterium 11
Menkes 11
DBA 11
Klebsiella 11
infectious diseases 11
angiomyolipoma 10
ash 10
CHS 10
hypertension 10
Harada 9
worms 9
adenocarcinoma 9
type 2 diabetes 9
rind 9
virus infection 9
lichen 9
glaucoma 9
Sweet 8
West 8
OCA4 8
plaque 8
colon cancer 8
SAR 8
fungal infection 8
squamous cell carcinoma 8
papillary thyroid cancer 8
Vogt-Koyanagi 8
genetic disorder 7
schizophrenia 7
CCD 7
melanoderma 7
macular degeneration 7
mimicry 7
fibrosarcoma 7
HGF 7
CCD 7
Horner's syndrome 7
minimal residual disease 7
glioma 7
cataract 7
dyschromia 6
PBT 6
plant disease 6
TOC 6
OCA1B 6
tuberous sclerosis 6
Epstein 6
ochronosis 6
mental retardation 6
lung cancer 6
ovarian cancer 6
mental retardation 6
atopic dermatitis 6
HIV 6
Thymus 5
renal cell carcinoma 5
Schmidt 5
NAME 5
colitis 5
hyperglycemia 5
SCID 5
PCA 5
pulmonary fibrosis 5
psychosis 5
malaria 5
WS2 5
X-linked ocular albinism 5
Thymus 5
leprosy 5
Infection 5
retinoblastoma 5
pruritus 5
Evans 5
glioblastoma multiforme 5
neurofibromatosis type 1 5
asthma 5
APC 5
dysplastic nevi 5
trichotillomania 5
osteoporosis 5
anemia 5
Thymus 5
lung carcinoma 5
stromal tumors 5
benign nevi 5
glioblastoma 5
skin tumor 5
Contact Dermatitis 5
lung metastases 5
hepatoblastoma 4
PLS 4
uveitis 4
tumor initiation 4
more...
Symptom
acidity 32
erythema 17
skin irritation 15
skin damage 12
pain 10
nausea 8
collapse 8
starvation 7
thinning 7
chills 6
photophobia 6
vomiting 6
agitation 6
diarrhea 5
exhaustion 5
tremor 4
DNA marker 3
anesthesia 3
Spots 3
HSA 3
Hudson 2
cough 2
dyspnea 2
weakness 2
ataxia 2
fasciculation 2
lethargy 1
Decreased activity 1
Lightening 1
myalgia 1
cachexia 1
dystonia 1
analgesia 1
pallor 1
emaciation 1
paresis 1
skin irritant 1
ENT 1
memory loss 1
fatigue 1
stigma 1
Overlying 1
microbial colonization 1
functional recovery 1
hypotonia 1
physical appearance 1
flushing 1
dental pain 1
insomnia 1
headache 1
menometrorrhagia 1
anorexia 1
ACHE 1
Drug
Dermatol 537
L-tyrosine 236
ascorbate 94
NADH 47
citric acid 41
lysine 40
IFN-gamma 35
ROS 34
Leaf 27
IL-2 23
vitamin E 19
Glycyrrhiza 18
CSF 18
ZnO 14
caffeine 14
Glutathione 13
Asn 13
Retinoic acid 12
Aloe 12
Gel 10
DNase I 8
lactose 8
Capsicum 7
CaCl2 7
CaCl2 7
CaCl2 7
MAP 7
Sesamol 6
G418 6
EE2 6
ENT 5
Bifidobacterium 5
TiO2 5
BH4 5
Ethanol 5
CAM 5
ampicillin 5
p75 4
MRC 4
Monit 4
Spectrum 4
Theophylline 4
THF 4
MOF 4
Fraction 4
Ginseng 4
3,4-Dihydroxyphenylalanine 4
Gly-Tyr-Gly 3
Histamine 3
Etoposide 3
CTC 3
Latanoprost 3
nitroglycerin 3
Premarin 3
ETA 3
CCL 3
Captopril 3
CTX 2
Portal 2
CTC 2
Hyaluronidase 2
Senna 2
NBT 2
Biopolymers 2
ISP 2
Xanthium 2
Tannic acid 2
Hyaluronidase 2
Angiotensin II 2
Rutin 2
Azithromycin 2
Viagra 2
Swertia 2
niacin 2
Viagra 2
Forskolin 2
Sinemet 2
Zmax 2
Indomethacin 2
Epigallocatechin 2
Vitamin A 2
Silica 2
Spectrum 2
Vitamin B 2
KAN 2
Scopolamine 2
DHT 2
Senna 2
Palmitoyl 2
Trifluoperazine 2
pyridoxal phosphate 2
NAG 2
ABC 2
NH3 2
SiO2 2
Coral 2
PCB 2
Compound 9 2
Omeprazole 2
Carbidopa 2
Papain 2
Gelatin 2
Ethylenediamine 2
DHT 2
Parkin 1
Nephron 1
Moxifloxacin 1
Malachite Green 1
R1881 1
Asparaginase 1
Methyldopa 1
Fluorescein 1
Ephedrae Herba 1
Cardiovasc 1
Sulla 1
FeCl3 1
Pronase 1
Growth hormone 1
Hypaque 1
Zinc sulfate 1
Loratadine 1
ALA 1
TRM 1
Axokine 1
Tinosorb S 1
FLM 1
Fragment 1
Clofibrate 1
Finasteride 1
Estriol 1
SPP 1
Acacia 1
Perphenazine 1
Pancreatin 1
Digenea 1
VCR 1
Cysteine hydrochloride 1
IPM 1
Vitamin E 1
Itraconazole 1
Imatinib 1
Tocopherol 1
KGF 1
Hoelen 1
Vitamin K 1
CEC 1
Ddc 1
Dasatinib 1
Digitalis 1
Emodin 1
Vitamin B12 1
PBZ 1
Areca 1
Zinc sulfate 1
GEO 1
Galactose 1
MDS 1
RFP 1
HCH 1
Gleevec 1
more...
Enzyme
tyrosinase 9065
peroxidase 693
DCF 499
phenol oxidase 466
catalase 362
superoxide dismutase 274
laccase 214
mitogen-activated protein kinase 190
acetylcholinesterase 167
protein kinase 144
catechol oxidase 137
cholinesterase 118
tyrosine hydroxylase 116
PAL 109
ERK 104
ascorbate peroxidase 80
trypsin 74
urease 68
urease 68
lipoxygenase 67
elastase 66
chitinase 62
reverse transcriptase 62
alkaline phosphatase 60
collagenase 56
protein kinase C 52
acid phosphatase 50
proteasome 47
xanthine oxidase 45
lipase 44
invertase 44
cellulase 43
glucose oxidase 40
glutathione reductase 39
MEK 38
ceruloplasmin 36
luciferase 34
lignin peroxidase 31
ascorbate oxidase 29
glutathione peroxidase 28
hyaluronidase 28
hyaluronidase 28
pectin methylesterase 26
ATPase 25
ACS 23
beta-galactosidase 23
glutathione S-transferase 22
adenylate cyclase 21
NQO1 20
RNA polymerase 19
pectinase 19
phenylalanine hydroxylase 19
chymotrypsin 19
transglutaminase 19
aryl-alcohol oxidase 19
xylanase 18
PAL 18
xylanase 18
azoreductase 17
lactate dehydrogenase 16
transcriptase 16
gamma-glutamyl transpeptidase 16
phosphodiesterase 16
caspase-3 14
beta-glucuronidase 14
beta-glucosidase 14
ACE 13
nitrate reductase 13
nitrate reductase 13
nitrate reductase 13
nitrate reductase 13
nitrate reductase 13
nitrate reductase 13
carbonic anhydrase 12
monoamine oxidase 12
phosphatidylinositol 3-kinase 12
alcohol dehydrogenase 12
cytochrome oxidase 12
focal adhesion kinase 11
thymidine kinase 11
aldehyde dehydrogenase 11
shikimate dehydrogenase 11
hexosaminidase 11
sucrase 11
GSK 11
lysozyme 10
beta-glucosidase 10
neuraminidase 10
lysyl oxidase 10
glucose dehydrogenase 10
aldehyde dehydrogenase 9
PAH 9
CAD 9
thioredoxin reductase 9
guanylate cyclase 8
glucose-6-phosphate dehydrogenase 8
aldehyde dehydrogenase 8
diaphorase 8
DNA polymerase 8
glyceraldehyde-3-phosphate dehydrogenase 8
alpha-glucosidase 8
aldehyde dehydrogenase 8
aldehyde dehydrogenase 8
subtilisin 8
DNase 7
pepsin 7
calcineurin 7
cellobiohydrolase 7
NADPH oxidase 7
NO synthase 7
NADPH oxidase 7
manganese peroxidase 7
firefly luciferase 7
chalcone synthase 7
MAP 7
AAE 7
demethylase 7
papain 7
chloramphenicol acetyltransferase 7
topoisomerase 7
ornithine decarboxylase 6
glyceraldehyde-3-phosphate dehydrogenase 6
dihydrofolate reductase 6
aureusidin synthase 6
ATP synthase 6
glutamate dehydrogenase 6
beta-1,3-glucanase 6
NADPH-diaphorase 6
phosphoinositide 3-kinase 6
dopamine beta-hydroxylase 6
glyceraldehyde-3-phosphate dehydrogenase 6
paraoxonase 6
porphobilinogen deaminase 6
histidine kinase 6
alcohol oxidase 6
cytosine deaminase 6
alpha-mannosidase 6
arginase 6
cathepsin D 6
glyceraldehyde-3-phosphate dehydrogenase 6
diaphorase 6
CD10 6
asparaginase 6
granzyme B 6
glyceraldehyde-3-phosphate dehydrogenase 6
carboxylesterase 6
topoisomerase 6
histidase 6
oxalate oxidase 5
deoxyribonuclease 5
RNase 5
RNase 5
PNGase F 5
methane monooxygenase 5
aldolase 5
AMPK 5
malate dehydrogenase 5
glutamate dehydrogenase 5
glutamate dehydrogenase 5
CD13 5
more...
Compound
tyrosine 822
Dec 725
copper 680
water 608
oxygen 574
L-DOPA 562
DNA 481
phenol 384
hydrogen 290
DPPH 236
sodium 225
methanol 221
Phe 210
Melanin 200
cysteine 191
ethanol 185
cAMP 180
Dopa 169
phosphate 143
ethyl acetate 143
hydroquinone 127
His 127
galactose 126
SDS 121
nitrogen 118
ammonia 115
sulfate 110
3,4-dihydroxyphenylalanine 110
GSH 109
GSH 109
Clin 99
iron 98
acetate 97
glucose 97
gallic acid 94
H2O2 89
alpha-MSH 87
PPO 85
ammonium 79
salt 78
zinc 77
calcium 73
alanine 73
Cu(II) 70
proline 67
tryptophan 65
nitric oxide 65
MTT 64
leucine 63
salicylic acid 62
arginine 61
AMP 59
bromide 59
lysine 58
silver 58
benzoic acid 51
methionine 50
resorcinol 50
thiourea 49
hexane 47
Catechol 47
acetone 46
NADH 46
acetic acid 46
tryptophan 45
Kojic acid 45
tryptophan 44
tryptophan 44
urea 44
Gly 43
kaempferol 43
Ascorbic acid 42
DAD 42
chloroform 41
p-cresol 41
potassium 39
PEG 38
serine 38
retinoic acid 37
benzene 37
acrylamide 36
Catechol 35
TOF 35
manganese 34
DEAE 34
NH2 34
Triton X-100 33
MEK 33
dichloromethane 33
ACTH 32
cadmium 31
nitrate 29
Resveratrol 29
acetonitrile 29
chalcone 29
ClO 27
Asp 27
p-cresol 27
EDTA 26
ClO 25
cyanide 25
DMSO 25
phosphorus 25
Dopamine 25
CO2 25
hydroxide 25
ATP 24
CAM 24
EDTA 24
Arbutin 24
ACS 23
ACS 23
DCIP 22
aldehyde 22
PEG 21
HCl 21
Tyrosine 21
hydrazine 21
Quercetin 20
CAP 20
COS 20
superoxide radical 20
CAP 20
PTU 20
benzaldehyde 20
boron 20
NADPH 20
NADPH 20
MNT 19
aldehyde 19
naphthalene 19
pyridine 18
azelaic acid 18
cGMP 18
benzaldehyde 17
protocatechuate 17
pyrene 17
CAT 17
threonine 17
silicon 17
CAT 17
CAT 17
glycerol 17
Chitosan 17
MDA 17
benzaldehyde 16
benzaldehyde 16
benzaldehyde 16
nickel 16
benzaldehyde 16
benzaldehyde 16
benzaldehyde 16
iodine 16
benzaldehyde 16
benzaldehyde 16
benzaldehyde 16
benzaldehyde 16
hydroxycinnamic acid 16
benzaldehyde 16
benzaldehyde 16
more...