Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.1.1.49 (glucose-6-phosphate dehydrogenase)
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Human Gene/Protein
OR11H4 12.0
glucose-6-phosphate dehydrogenase 12.0
G6PD1 12.0
G6PDH 12.0
ITGB2 protein 12.0
GPD 12.0
Similar to catalase 12.0
26S protease regulatory subunit 8 12.0
OR10A6 12.0
glucose-6-phosphate 1-dehydrogenase 12.0
6-phosphogluconate dehydrogenase 11.1
OR2AG2 11.0
G6PD protein 11.0
eukaryotic translation initiation factor 1A, Y-linked 11.0
NADH dehydrogenase (ubiquinone) Fe-S protein 2 11.0
G6d 11.0
ME2 protein 11.0
6-phosphogluconolactonase 10.8
TSPY2 10.4
MRPS2 10.4
NOD5 10.4
Glucose-6-phosphate 1-dehydrogenase 10.4
Nucleoside diphosphokinase 10.2
glycerol-3-phosphate acyltransferase, mitochondrial 10.2
EIF4A 10.2
Malic dehydrogenase 10.1
TMEM51 10.0
carbohydrate kinase-like 10.0
mannose phosphate isomerase 9.9
NADP+-specific isocitrate dehydrogenase 9.8
GYPC 9.7
acid sphingomyelinase-like phosphodiesterase 9.7
ACON 9.7
Glucose-6-phosphate dehydrogenase 9.5
glucose-6-phosphate dehydrogenase variant 9.4
G6PD 9.4
6PGD 9.4
L-alpha-glycerophosphate dehydrogenase 9.4
NADK 9.3
PFK-A 9.3
PDH 9.2
Matrix metalloproteinase 11 9.2
MAD4 9.2
NAD(+) kinase 9.2
LDLB 9.2
ubiquitin-conjugating enzyme E2A 9.2
Malic enzyme 9.2
NADPH2 9.2
guanosine monophosphate reductase 9.1
ribose 5-phosphate isomerase 9.1
heterogeneous nuclear ribonucleoprotein A3 9.0
P35B 9.0
Folate binding protein 9.0
transaldolase 9.0
G3PD 8.9
MNSOD 8.9
hexokinase 8.9
isocitric dehydrogenase 8.8
LUC7L 8.8
OLFM1 8.8
NADH3 8.8
isocitrate dehydrogenase 8.7
calpain 6 8.7
elongation of very long chain fatty acids protein 8.7
aflatoxin B1-aldehyde reductase 8.7
RPS3a 8.7
ATPase homolog 8.7
EIF3F 8.7
SMAX2 8.7
6-phosphofructokinase 8.7
Hexokinase 8.6
phosphoglucose isomerase 8.6
NADP+-dependent isocitrate dehydrogenase 8.6
phosphorylase, glycogen 8.5
FN3K-related protein 8.5
Mucin 4 8.5
L13A 8.5
gluconate kinase 8.5
malate dehydrogenase 8.5
NADP-dependent malic enzyme 8.4
more...
Disease
G6PD deficiency anemia 12.0
G6PD, VAL68MET, ASN126ASP 12.0
Dietetic microangiopathy 12.0
Enzymopathy 11.0
favism 10.6
G6PD deficiency 10.2
Acute hemolytic anemia 10.0
hereditary nonspherocytic hemolytic anemia 9.4
Color vision defects 9.0
GSM1 9.0
Dietary selenium deficiency 8.5
PGL4 8.4
Acquired methemoglobinemia 8.4
sideroblastosis 8.1
Embryopathy 8.0
FGD1 8.0
PGL2 7.7
allergic arthritis 7.7
pyruvate kinase deficiency 7.7
Liver mass 7.7
Sickle cell trait 7.6
neonatal jaundice 7.6
congenital hemolytic anemia 7.6
Extrahepatic cholestasis 7.6
sulfa allergy 7.5
enzyme deficiency 7.5
Neutrophil dysfunction 7.5
preneoplastic state 7.4
hemolytic jaundice 7.3
thalassemia trait 7.3
methemoglobinemia 7.1
kernicterus 7.1
color blindness 7.0
FIPA 7.0
hyperlysinemia 7.0
ABO hemolytic disease of the newborn 7.0
malignant myeloma 6.9
tocopherol deficiency 6.8
PGL3 6.7
hemolytic anemia 6.7
Plasmodium vivax malaria 6.7
hereditary anemia 6.6
homocystinemia 6.6
Hepatocarcinogenesis 6.5
Glycerol kinase deficiency 6.5
PDH deficiency 6.5
Bovine babesiosis 6.4
Erythroleukemia 6.4
Herpetosoma 6.4
riboflavin deficiency 6.4
Hers 6.4
hereditary spherocytosis 6.3
Dermatitis artefacta 6.3
Fetal distress 6.2
blood loss anemia 6.2
Toxicosis 6.1
dyserythropoietic anemia 6.1
Southeast Asian ovalocytosis 6.1
hemoglobinuria 6.1
Biotin deficiency 6.0
ABO incompatibility 6.0
hematological abnormality 5.9
Gram-positive bacteremia 5.9
hyperbilirubinemia 5.9
thalassemia minor 5.8
avitaminosis 5.8
FCU 5.8
BHD 5.8
Bazin 5.8
MPE 5.7
GSH 5.7
hereditary elliptocytosis 5.6
Oxygen toxicity 5.5
CDA II 5.4
blood group incompatibility 5.3
BHD 5.3
diabetic cataract 5.3
PPP 5.3
diphyllobothriasis 5.2
alcoholic cardiomyopathy 5.2
more...
Symptom
cracked lips 7.8
Reticulocytosis 6.4
dark urine 6.2
feeling tired 5.7
abiotrophy 5.7
lumbar back pain 5.6
hyperoxia 5.0
loss of equilibrium 4.9
chromosome marker 4.8
ACHE 4.1
Anoxia 3.9
No adverse effect 3.7
starvation 3.5
Spots 3.2
emaciation 2.9
Decreased activity 2.9
cyanosis 2.9
ketonuria 2.9
polydipsia 2.5
polyuria 2.4
pallor 2.3
exhaustion 2.1
splenomegaly 2.0
eds 1.9
muscle rigidity 1.9
hepatomegaly 1.8
tonic-clonic seizure 1.6
agitation 1.6
hypotonia 1.5
hepatosplenomegaly 1.5
HSA 1.4
abdominal discomfort 1.2
incoordination 1.2
lethargy 1.1
twitching 1.0
fever of unknown origin 1.0
chorea 1.0
hypothermia 0.9
Ill 0.9
acute stress 0.8
shortness of breath 0.6
asthenia 0.6
sore throat 0.6
cachexia 0.5
hunger 0.5
erythema 0.3
anorexia 0.2
acidity 0.1
hypercapnia 0.0
chills -0.1
fatigue -0.1
vomiting -0.2
tremor -0.2
syncope -0.2
wheezing -0.2
abdominal pain -0.3
ataxia -0.4
dyspnea -0.5
collapse -0.5
nausea -0.5
flushing -0.6
respiratory distress -0.7
stigma -0.7
functional recovery -0.7
anesthesia -0.8
spasm -0.9
cough -1.0
diarrhea -1.0
seizures -1.1
weakness -1.2
nausea and vomiting -1.2
dizziness -1.2
back pain -1.6
overweight -2.7
analgesia -2.8
pain -3.7
headache -3.8
Drug
Chloroquine hydrochloride 12.0
Isepamicin sulfate 11.0
Alpha-D-Glucose 11.0
Aczone 10.4
Anise oil 10.4
Primaquine 9.1
Hexobendine 8.8
Rasburicase 8.1
Hakka 7.7
Kytril 7.4
Tuareg 7.4
Kytril 7.4
Berberine chloride 7.2
Tallow 7.2
Metoclopramide hydrochloride 7.0
Benfotiamine 6.9
Glucose-6-Phosphate 6.7
Avilamycin 6.7
Lead acetate 6.7
Rasburicase 6.6
Cibacron Blue 6.4
Soybean oil 6.3
Marcaine 6.3
Arava 6.1
Pentane 6.0
Primperan 6.0
Pyridoxal phosphate 5.8
Sterile water 5.8
Dithranol 5.7
Hyoscyamine 5.7
Landel 5.7
Atovaquone 5.6
NADH 5.6
Tirapazamine 5.5
Guar gum 5.5
Clofibrate 5.4
Teniposide 5.4
Fructose 5.4
Malonaldehyde 5.4
Bactrim 5.3
Fipronil 5.3
Dantrolene sodium 5.2
Atovaquone 5.2
Liposyn 5.2
Fansidar 5.1
Safflower 5.1
Fansidar 5.0
Trimethoprim-sulfamethoxazole 5.0
Pyridoxal 5.0
Glutathione 4.9
Palmitoyl 4.8
linolenate 4.8
Papaverine 4.7
Nitazoxanide 4.7
Fenbendazole 4.7
Monosodium glutamate 4.7
Phosphatidylserine 4.6
EPL 4.6
Xylocaine 4.6
Galactose 4.6
Adenosine triphosphate 4.5
Tibolone 4.5
CrCl3 4.4
vitamin E 4.4
ascorbate 4.4
Cinacalcet 4.3
Ethane 4.3
MDM 4.3
Methylene blue 4.3
NBT 4.2
PE2 4.2
L-Ser 4.2
Maltose 4.2
Gliclazide 4.2
Cytidine 4.1
Ammonium chloride 4.1
Cobalamin 3.9
Bezafibrate 3.9
Ketotifen 3.8
Vitamin B 3.7
more...
Enzyme
glycerin-3-phosphate dehydrogenase 12.0
glucose-6-phosphate dehydrogenase 12.0
EC 2.3.1.60 12.0
EC 1.5.1.18 12.0
glucose phosphomutase 12.0
allose kinase 12.0
6-phosphogluconate dehydrogenase 11.1
6-phosphogluconate dehydrogenase 11.0
maltose 1-epimerase 11.0
6-phosphogluconolactonase 10.7
citrate cleavage enzyme 10.6
EC 1.6.2.5 10.4
2-ketogluconate reductase 10.4
4NQO reductase 10.4
2-ketogluconate kinase 10.4
L-arabinose 1-dehydrogenase 10.4
EC 1.1.99.10 10.4
6-phosphogluconate dehydratase 10.3
EC 1.1.1.40 10.0
gluconate dehydrogenase 9.9
EC 1.1.1.38 9.9
2-keto-3-deoxy-6-phosphogluconate aldolase 9.8
gluconokinase 9.7
PDH 9.3
calpain 6 9.2
glycerol 3-phosphatase 9.1
glyoxylate dehydrogenase 9.0
hexokinase 8.9
transaldolase 8.8
anhydrotetracycline oxygenase 8.8
phosphoglucomutase 8.8
phosphoglucose isomerase 8.8
isocitrate dehydrogenase 8.7
isocitrate dehydrogenase 8.6
NAD+ kinase 8.6
EC 1.1.1.47 8.6
glycerol-3-phosphate dehydrogenase 8.5
glycerol 3-phosphate dehydrogenase 8.5
polyphosphate glucokinase 8.5
valine dehydrogenase 8.5
ribulose 5-phosphate 3-epimerase 8.5
malate dehydrogenase 8.5
glutathione reductase 8.4
glycerol-3-phosphate dehydrogenase 8.4
pyruvate kinase 8.3
phosphofructokinase 8.3
transketolase 8.3
phosphoglyceromutase 8.3
ADP-dependent glucokinase 8.3
mannokinase 8.3
3'(2'),5'-bisphosphate nucleotidase 8.3
NADH kinase 8.3
beta-hydroxybutyrate dehydrogenase 8.2
MDH 8.2
gluconate dehydratase 8.2
phosphomannose isomerase 8.2
MDH 8.1
glucose-6-phosphatase 8.1
L-serine hydro-lyase 8.0
fructose 1,6-bisphosphatase 7.9
glucokinase 7.9
triokinase 7.9
octanol dehydrogenase 7.8
sucrose-phosphatase 7.8
GPH 7.8
citrate lyase 7.8
shikimate dehydrogenase 7.8
ribose-5-phosphate isomerase 7.8
K+-transporting ATPase 7.7
EC 5.3.3.8 7.7
phosphofructokinase 1 7.7
fructokinase 7.7
mannitol dehydrogenase 7.7
trehalulose synthase 7.7
nicotinamide adenine dinucleotide glycohydrolase 7.7
glucose-1-phosphatase 7.7
GDP-mannose dehydrogenase 7.6
aldolase 7.6
D-galactose dehydrogenase 7.6
energy-linked transhydrogenase 7.5
more...
Compound
Butyl disulfide 11.0
Agaricic acid 11.0
6-phosphogluconolactone 10.9
ethylenesulfonic acid 10.4
Triethyloxonium tetrafluoroborate 10.4
ethylenesulfonic acid 10.4
C13H10N2O 10.0
6-phosphogluconate 9.7
Disperse Red 11 9.7
Pamaquine 9.7
Neotetrazolium 9.5
3,21-dihydroxypregnan-20-one 9.4
Primaquine 9.1
pentose 9.1
pentose 9.1
pentose 9.1
Glucose 6-phosphate 9.1
Disperse Blue 3 9.0
pentose 9.0
8-Aminoquinoline 8.8
Antheraxanthin 8.8
PDH 8.8
2-keto-3-deoxy-6-phosphogluconate 8.8
L-Ribulose 5-phosphate 8.7
6-aminonicotinamide 8.6
glucose-6-phosphate 8.6
S-phenylcysteine 8.4
Isopulegol 8.4
Isopulegol 8.3
1-butanesulfonic acid 8.3
Oxythiamine 8.3
butyl 4-hydroxybenzoate 8.3
sedoheptulose 7-phosphate 8.3
Coenzyme F420 8.2
4-chlorobutyl 8.2
Primaquine phosphate 8.2
NADP 8.1
TNBT 8.1
Imidazoleacetic acid 8.1
2,2',5,5'-TCB 8.1
Pretilachlor 8.1
Cycloartenol 8.0
butyl 4-hydroxybenzoate 8.0
Anhydrotetracycline 8.0
cyclohexylacetic acid 8.0
Endothall 7.9
Salicylaldoxime 7.9
Validamycin A 7.8
Epiandrosterone 7.8
Chloral 7.8
ribose-5-phosphate 7.7
4-propylphenol 7.7
Procion Yellow 7.6
N-acetyl-glucosamine-1-phosphate 7.6
4-diphosphocytidyl-2C-methyl-D-erythritol 7.6
Fraxetin 7.5
allyl formate 7.5
Ansamitocin P-3 7.5
3-mercapto-1,2-propanediol 7.4
Encephabol 7.4
Diamide 7.4
MEZ 7.4
Pyruvate kinase 7.3
Dithio 7.3
benzyl thiocyanate 7.3
NADPH 7.3
NADPH 7.3
Methyl linoleate 7.2
Xylulose 7.1
3-Aminopyridine 7.1
diethyl phosphonate 7.1
Berberine chloride 7.1
hexose 7.1
hexose 7.1
hexose 7.1
Aminoantipyrine 7.0
AD 32 7.0
8-Hydroxyguanine 7.0
D-gluconate 7.0
Alliin 7.0
more...