Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.1.1.49 (glucose-6-phosphate dehydrogenase)
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Human Gene/Protein
OR11H4 12.0
OR10A6 12.0
glucose-6-phosphate dehydrogenase 12.0
G6PDH 12.0
Similar to catalase 12.0
ITGB2 protein 12.0
GPD 12.0
26S protease regulatory subunit 8 12.0
glucose-6-phosphate 1-dehydrogenase 12.0
G6PD1 12.0
6-phosphogluconate dehydrogenase 11.1
eukaryotic translation initiation factor 1A, Y-linked 11.0
NADH dehydrogenase (ubiquinone) Fe-S protein 2 11.0
G6PD protein 11.0
ME2 protein 11.0
OR2AG2 11.0
G6d 11.0
6-phosphogluconolactonase 10.8
TSPY2 10.4
MRPS2 10.4
Glucose-6-phosphate 1-dehydrogenase 10.4
NOD5 10.4
Nucleoside diphosphokinase 10.2
EIF4A 10.2
glycerol-3-phosphate acyltransferase, mitochondrial 10.2
Malic dehydrogenase 10.1
carbohydrate kinase-like 10.0
TMEM51 10.0
mannose phosphate isomerase 9.9
NADP+-specific isocitrate dehydrogenase 9.8
GYPC 9.7
ACON 9.7
acid sphingomyelinase-like phosphodiesterase 9.7
Glucose-6-phosphate dehydrogenase 9.5
glucose-6-phosphate dehydrogenase variant 9.4
G6PD 9.4
6PGD 9.4
L-alpha-glycerophosphate dehydrogenase 9.4
NADK 9.3
PFK-A 9.3
more...
Disease
Dietetic microangiopathy 12.0
G6PD deficiency anemia 12.0
G6PD, VAL68MET, ASN126ASP 12.0
Enzymopathy 11.0
favism 10.6
G6PD deficiency 10.2
Acute hemolytic anemia 10.0
hereditary nonspherocytic hemolytic anemia 9.4
GSM1 9.0
Color vision defects 9.0
Dietary selenium deficiency 8.5
PGL4 8.4
Acquired methemoglobinemia 8.4
sideroblastosis 8.1
Embryopathy 8.0
FGD1 8.0
PGL2 7.7
allergic arthritis 7.7
pyruvate kinase deficiency 7.7
Liver mass 7.7
neonatal jaundice 7.6
Sickle cell trait 7.6
congenital hemolytic anemia 7.6
Extrahepatic cholestasis 7.6
sulfa allergy 7.5
enzyme deficiency 7.5
Neutrophil dysfunction 7.5
preneoplastic state 7.4
hemolytic jaundice 7.3
thalassemia trait 7.3
methemoglobinemia 7.1
kernicterus 7.1
color blindness 7.0
FIPA 7.0
hyperlysinemia 7.0
ABO hemolytic disease of the newborn 7.0
malignant myeloma 6.9
tocopherol deficiency 6.8
PGL3 6.7
hemolytic anemia 6.7
more...
Symptom
cracked lips 7.8
Reticulocytosis 6.4
dark urine 6.2
feeling tired 5.7
abiotrophy 5.7
lumbar back pain 5.6
hyperoxia 5.0
loss of equilibrium 4.9
chromosome marker 4.8
ACHE 4.1
Anoxia 3.9
No adverse effect 3.7
starvation 3.5
Spots 3.2
emaciation 2.9
Decreased activity 2.9
cyanosis 2.9
ketonuria 2.9
polydipsia 2.5
polyuria 2.4
pallor 2.3
exhaustion 2.1
splenomegaly 2.0
eds 1.9
muscle rigidity 1.9
hepatomegaly 1.8
tonic-clonic seizure 1.6
agitation 1.6
hypotonia 1.5
hepatosplenomegaly 1.5
HSA 1.4
abdominal discomfort 1.2
incoordination 1.2
lethargy 1.1
twitching 1.0
fever of unknown origin 1.0
chorea 1.0
hypothermia 0.9
Ill 0.9
acute stress 0.8
more...
Drug
Chloroquine hydrochloride 12.0
Isepamicin sulfate 11.0
Alpha-D-Glucose 11.0
Aczone 10.4
Anise oil 10.4
Primaquine 9.1
Hexobendine 8.8
Rasburicase 8.1
Hakka 7.7
Kytril 7.4
Kytril 7.4
Tuareg 7.4
Berberine chloride 7.2
Tallow 7.2
Metoclopramide hydrochloride 7.0
Benfotiamine 6.9
Avilamycin 6.7
Glucose-6-Phosphate 6.7
Lead acetate 6.7
Rasburicase 6.6
Cibacron Blue 6.4
Soybean oil 6.3
Marcaine 6.3
Arava 6.1
Pentane 6.0
Primperan 6.0
Sterile water 5.8
Pyridoxal phosphate 5.8
Dithranol 5.7
Hyoscyamine 5.7
Landel 5.7
Atovaquone 5.6
NADH 5.6
Tirapazamine 5.5
Guar gum 5.5
Clofibrate 5.4
Teniposide 5.4
Fructose 5.4
Malonaldehyde 5.4
Bactrim 5.3
more...
Enzyme
glucose-6-phosphate dehydrogenase 12.0
EC 2.3.1.60 12.0
allose kinase 12.0
glucose phosphomutase 12.0
EC 1.5.1.18 12.0
glycerin-3-phosphate dehydrogenase 12.0
6-phosphogluconate dehydrogenase 11.1
6-phosphogluconate dehydrogenase 11.0
maltose 1-epimerase 11.0
6-phosphogluconolactonase 10.7
citrate cleavage enzyme 10.6
2-ketogluconate kinase 10.4
2-ketogluconate reductase 10.4
EC 1.6.2.5 10.4
EC 1.1.99.10 10.4
4NQO reductase 10.4
L-arabinose 1-dehydrogenase 10.4
6-phosphogluconate dehydratase 10.3
EC 1.1.1.40 10.0
gluconate dehydrogenase 9.9
EC 1.1.1.38 9.9
2-keto-3-deoxy-6-phosphogluconate aldolase 9.8
gluconokinase 9.7
PDH 9.3
calpain 6 9.2
glycerol 3-phosphatase 9.1
glyoxylate dehydrogenase 9.0
hexokinase 8.9
transaldolase 8.8
anhydrotetracycline oxygenase 8.8
phosphoglucomutase 8.8
phosphoglucose isomerase 8.8
isocitrate dehydrogenase 8.7
isocitrate dehydrogenase 8.6
NAD+ kinase 8.6
EC 1.1.1.47 8.6
glycerol-3-phosphate dehydrogenase 8.5
glycerol 3-phosphate dehydrogenase 8.5
polyphosphate glucokinase 8.5
valine dehydrogenase 8.5
more...
Compound
Agaricic acid 11.0
Butyl disulfide 11.0
6-phosphogluconolactone 10.9
Triethyloxonium tetrafluoroborate 10.4
ethylenesulfonic acid 10.4
ethylenesulfonic acid 10.4
C13H10N2O 10.0
6-phosphogluconate 9.7
Pamaquine 9.7
Disperse Red 11 9.7
Neotetrazolium 9.5
3,21-dihydroxypregnan-20-one 9.4
Primaquine 9.1
pentose 9.1
pentose 9.1
pentose 9.1
Glucose 6-phosphate 9.1
Disperse Blue 3 9.0
pentose 9.0
8-Aminoquinoline 8.8
Antheraxanthin 8.8
PDH 8.8
2-keto-3-deoxy-6-phosphogluconate 8.8
L-Ribulose 5-phosphate 8.7
6-aminonicotinamide 8.6
glucose-6-phosphate 8.6
Isopulegol 8.4
S-phenylcysteine 8.4
butyl 4-hydroxybenzoate 8.3
Isopulegol 8.3
sedoheptulose 7-phosphate 8.3
Oxythiamine 8.3
1-butanesulfonic acid 8.3
4-chlorobutyl 8.2
Coenzyme F420 8.2
Primaquine phosphate 8.2
NADP 8.1
TNBT 8.1
2,2',5,5'-TCB 8.1
Imidazoleacetic acid 8.1
more...