Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:1.1.1.41 (isocitrate dehydrogenase)
3,101 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein isocitrate dehydrogenase 2945 NADP 554 NADPH 402 malate dehydrogenase 385 NAD 367 IDH1 274 glucose-6-phosphate dehydrogenase 262 lactate dehydrogenase 242 citrate synthase 223 IDH2 199 ATP 196 IDH 190 NADH 189 Sep 185 isocitric dehydrogenase 164 NADP+ 158 Mol 158 aconitase 149 glutamate dehydrogenase 136 6-phosphogluconate dehydrogenase 124 ADP 113 NAD+ 110 aspartate aminotransferase 105 pyruvate kinase 94 alpha-ketoglutarate dehydrogenase 92 superoxide dismutase 89 NADP-dependent isocitrate dehydrogenase 87 catalase 82 pyruvate dehydrogenase 81 glutathione reductase 79 fumarase 77 hexokinase 73 alkaline phosphatase 71 TCA 70 phosphofructokinase 66 alanine aminotransferase 65 p53 63 GSH 63 ATPase 60 AMP 59 glutathione peroxidase 58 acid phosphatase 56 cytochrome c oxidase 49 pyruvate carboxylase 47 phosphatase 47 alcohol dehydrogenase 47 decarboxylating 46 histone 44 CO2 42 fumarate hydratase 41 insulin 41 Pseudomonas 40 glutamine synthetase 39 cytochrome 38 methylguanine-DNA methyltransferase 37 creatine kinase 37 reductase 36 dimeric 36 ACL 35 2-oxoglutarate dehydrogenase 34 esterase 34 NADH dehydrogenase 33 glyceraldehyde-3-phosphate dehydrogenase 33 NMR 30 oxidoreductase 30 Isocitrate dehydrogenase 29 phosphoenolpyruvate carboxykinase 29 phosphoenolpyruvate carboxylase 29 enolase 29 fatty acid synthase 28 MRI 28 isocitrate dehydrogenase 1 28 BRAF 26 phosphoglucose isomerase 26 microsomal 26 ATP synthase 25 Gen 25 glucose-6-phosphatase 24 SDS 24 cytochrome c 23 more...

Disease cancer 339 tumor 302 glioma 242 glioblastoma 139 acute myeloid leukemia 131 GSH 63 brain tumor 56 tumorigenesis 49 glioblastoma multiforme 41 astrocytoma 37 leukemia 34 oligodendroglioma 33 cold 31 carcinogenesis 31 diabetes 27 carcinoma 26 SDS 24 tumor progression 22 ATRX 21 Glioblastoma 20 obesity 20 melanoma 18 ischemia 18 tumor growth 17 chondrosarcoma 17 breast cancer 16 myelodysplastic syndrome 15 Mycobacterium 15 depression 14 anaplastic astrocytoma 14 myocardial infarction 14 hepatocellular carcinoma 13 metastases 12 thalassemia 12 mole 12 pheochromocytoma 12 ICD 12 tuberculosis 11 fatty liver 11 BDB 11 mole 11 mental retardation 10 mental retardation 10 type 2 diabetes 10 sarcoma 10 primary tumor 9 ATM 9 leukemogenesis 9 hematologic malignancies 9 PCC 9 Parkinson's disease 9 lung cancer 9 lymphoma 9 hyperglycemia 9 malnutrition 8 epilepsy 8 Leukemia 8 prostate cancer 8 colon cancer 8 heart failure 8 adenocarcinoma 8 gliosarcoma 7 colorectal cancer 7 brain cancer 7 hepatitis 7 aggressiveness 7 MRS 6 renal cell carcinoma 6 hyperlipidemia 6 metabolic syndrome 6 Cholangiocarcinoma 6 hyperbilirubinemia 6 B-cell lymphoma 6 iron deficiency 6 SEM 5 cerebral ischemia 5 uterus 5 stroke 5 Cholangiocarcinoma 5 Klebsiella 5 more...

Symptom starvation 21 exhaustion 11 seizures 11 weakness 6 headache 5 nausea 5 anesthesia 4 dyspnea 3 vomiting 3 fatigue 3 hypothermia 3 collapse 3 pain 3 diarrhea 2 agitation 2 cough 2 Spots 2 acidity 2 functional recovery 2 flushing 2 nausea and vomiting 2 numbness 1 asthenia 1 constipation 1 Decreased activity 1 Central post-stroke pain 1 hyperoxia 1 Gasping 1 oliguria 1 hunger 1 tremor 1 dystonia 1 twitching 1 blurred vision 1 ataxia 1 thinning 1 shortness of breath 1 eds 1 nasal discharge 1 hypercapnia 1 Anoxia 1 lethargy 1 syncope 1 hypocapnia 1 decreased appetite 1 neurological disability 1 arthralgia 1 hypotonia 1 myalgia 1

Drug NADH 194 citric acid 119 lysine 52 ascorbate 32 ROS 13 Gel 12 FAD 11 vitamin E 9 Adriamycin 6 Glycerol 5 Leaf 5 EE2 4 Asn 4 Cardiovasc 4 MAP 4 Glutathione 4 Nitric Oxide 3 L-tyrosine 3 Ethanol 3 ABC 3 Capsicum 3 Fructose 3 NH3 3 Dermatol 3 lactose 3 ROC 2 Citric acid 2 Rasburicase 2 ADR 2 Frontal 2 Bevacizumab 2 Depo-Provera 2 Kenyan 2 Angiotensin II 2 Acacia 2 MgSO4 2 Clofibrate 2 Tween 40 2 MDS 2 ETS 2 ID2 1 DHT 1 Kaolin 1 Parkin 1 CSI 1 MEA 1 Sodium nitroprusside 1 ETA 1 CTX 1 Guanidine 1 Xanthium 1 Lactase 1 Indomethacin 1 Nephron 1 ZnO 1 Parkin 1 Lead acetate 1 Alanine 1 EPI 1 Palmitoyl 1 CTC 1 Lysine hydrochloride 1 Arsenic trioxide 1 C3H8 1 Carboxyatractyloside 1 Premarin 1 SMP 1 CTT 1 GEO 1 Mutagen 1 DNase I 1 CaCl2 1 Artesunate 1 Emodin 1 CDP 1 Midostaurin 1 G-CSF 1 Kainic acid 1 niacin 1 Honey 1 more...

Enzyme isocitrate dehydrogenase 3101 isocitrate dehydrogenase 2960 malate dehydrogenase 432 glucose-6-phosphate dehydrogenase 323 succinate dehydrogenase 272 lactate dehydrogenase 270 citrate synthase 233 aconitase 172 alpha-ketoglutarate dehydrogenase 151 glutamate dehydrogenase 141 glutamate dehydrogenase 140 glutamate dehydrogenase 138 6-phosphogluconate dehydrogenase 127 6-phosphogluconate dehydrogenase 127 aspartate aminotransferase 120 fumarase 116 pyruvate dehydrogenase 107 superoxide dismutase 102 isocitrate lyase 95 pyruvate kinase 94 alanine aminotransferase 90 catalase 87 pyruvate dehydrogenase 82 pyruvate dehydrogenase 81 glutathione reductase 81 hexokinase 73 alkaline phosphatase 72 ATPase 71 phosphofructokinase 70 diaphorase 60 glutathione peroxidase 59 phosphoenolpyruvate carboxykinase 59 phosphoenolpyruvate carboxykinase 58 acid phosphatase 57 phosphoenolpyruvate carboxykinase 57 cytochrome oxidase 52 alcohol dehydrogenase 50 phosphoglucose isomerase 50 aldolase 49 pyruvate carboxylase 48 creatine kinase 48 phosphoglucomutase 47 ERK 46 complex I 46 glycerol-3-phosphate dehydrogenase 42 glyceraldehyde-3-phosphate dehydrogenase 42 glutamine synthetase 39 malate synthase 39 glycerol-3-phosphate dehydrogenase 39 succinic dehydrogenase 38 glyceraldehyde-3-phosphate dehydrogenase 36 glyceraldehyde-3-phosphate dehydrogenase 36 NADH dehydrogenase 35 glyceraldehyde-3-phosphate dehydrogenase 34 phosphoenolpyruvate carboxylase 33 glyceraldehyde-3-phosphate dehydrogenase 33 enolase 31 STK3 31 acetylcholinesterase 29 ATP synthase 28 diaphorase 26 peroxidase 25 glucose-6-phosphatase 25 transhydrogenase 24 adenylate kinase 22 glutamate synthase 22 beta-hydroxybutyrate dehydrogenase 22 CPR 21 EC 1.1.1.40 20 glutamate synthase 20 oxoglutarate dehydrogenase 20 sorbitol dehydrogenase 20 phosphorylase 20 SCS 19 glutamate synthase 18 DNA methyltransferase 17 aldehyde dehydrogenase 17 NADPH-diaphorase 16 succinyl-CoA synthetase 16 glutathione S-transferase 16 more...

Compound NADP 714 NAD 476 isocitrate 446 NADPH 410 NADPH 402 NAD 367 glucose 364 2-oxoglutarate 331 DNA 268 phosphate 262 oxygen 247 Dec 203 ATP 196 NADH 194 glutamate 175 acetate 175 hydroxyglutarate 167 ADP 116 ADP 113 ADP 113 nitrogen 110 nicotinamide 106 Clin 93 pentose 89 pentose 89 pentose 89 pentose 89 calcium 83 glutamine 75 TCA 72 glycerol 71 water 69 GSH 68 GSH 68 sodium 65 alanine 65 lysine 61 AMP 60 CO2 59 acetyl-CoA 57 manganese 54 ammonium 52 hydrogen 52 arginine 51 alcohol dehydrogenase 47 CoA 47 iron 46 Mg2+ 46 sulfate 43 ethanol 35 tyrosine 35 urea 34 salt 34 glucose-6-phosphate 32 cysteine 30 zinc 30 ammonia 30 His 30 hexose 29 serine 29 hexose 29 hexose 29 hexose 29 pyridine 27 succinic acid 27 SDS 26 CIT 26 leucine 24 oxalacetate 24 copper 23 nitric oxide 23 Asp 22 methionine 22 glutamic acid 20 H2O2 20 Glutamate 20 galactose 19 nitrate 19 TOF 19 phosphorus 17 more...

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