Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.1.1.41 (isocitrate dehydrogenase)
 3,101 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
actin-related protein T2 13.3
H-IDH gamma 13.3
isocitrate dehydrogenase 13.3
CDH14 13.3
6-phosphogluconate dehydrogenase, decarboxylating 13.3
isocitric dehydrogenase 13.3
NAD-IDH 12.7
NADP+-specific isocitrate dehydrogenase 12.5
cadherin 18, type 2 12.3
cholinergic receptor, nicotinic, delta polypeptide 12.3
60S ribosomal protein L23 12.3
outer dense fiber protein 2 12.3
H-IDH alpha 12.3
flavoprotein-linked monooxygenase 12.3
NADH dehydrogenase flavoprotein 1 12.3
H3 histone, family 3A 12.3
WD repeat and FYVE domain containing 3 12.3
ATL-derived PMA-responsive peptide 12.3
ME2 protein 12.3
IDH3A 11.9
IDH3B 11.9
NADP-dependent isocitrate dehydrogenase 11.8
Glucose-6-phosphate 1-dehydrogenase 11.7
D-2-hydroxyglutarate dehydrogenase 11.6
tubulin alpha-1 chain 11.5
NAD+-isocitrate dehydrogenase 11.4
ACTIN-2 11.3
ATP synthase gamma chain 11.3
IDH3G 11.3
PECI 11.3
myosin-Ic 11.3
NADP+-dependent isocitrate dehydrogenase 11.2
IDH2 11.2
actin-related protein 6 11.0
translocon-associated protein delta 11.0
aconitate hydratase 10.9
sentrin/SUMO-specific protease 10.9
IDH 10.8
alpha thalassemia/mental retardation syndrome X-linked 10.8
UL16-binding protein 3 10.7
more...
Disease
adult brainstem glioma 12.3
Oligoastrocytoma 11.7
Oligoastrocytoma 11.7
adult pilocytic astrocytoma 10.5
ovarian mixed germ cell tumor 10.2
partial trisomy 2q 10.0
BDB 10.0
Anaplastic oligodendroglioma 9.4
Tanycytic ependymoma 9.4
Diffuse astrocytoma 9.4
Oligodendroglioma 9.3
Periosteal chondroma 9.2
Coxiella infection 9.0
Gliosarcoma 8.9
Waldenstrom's disease 8.9
ATRX 8.4
Withdrawal bleeding 8.2
adult brain tumor 7.8
Herpetosoma 7.7
Maffucci's syndrome 7.7
oligodendroglioma 7.6
RAEB-2 7.6
mixed gliomas 7.4
CPX 7.3
giant cell glioblastoma 7.3
refractory cytopenia with multilineage dysplasia 7.0
FAB M1 6.9
anaplastic astrocytoma 6.9
angioimmunoblastic T-cell lymphoma 6.7
enchondromatosis 6.7
gliosarcoma 6.6
AT/RT 6.5
AML progression 6.5
glioma 6.3
Hepatocarcinogenesis 6.3
glioblastoma 6.3
enchondroma 6.3
embryonal tumor 6.2
Glioblastoma 6.1
syndrome X 6.1
more...
Symptom
Central post-stroke pain 8.5
Gasping 7.4
Spots 5.5
Decreased activity 4.3
Anoxia 4.2
neurological disability 3.5
eds 3.3
decreased appetite 3.1
starvation 3.1
exhaustion 3.0
nasal discharge 2.9
hypocapnia 2.6
oliguria 2.5
twitching 2.3
blurred vision 2.3
asthenia 2.0
flushing 1.7
nausea 1.1
nausea and vomiting 1.1
numbness 1.0
shortness of breath 1.0
hyperoxia 1.0
hunger 0.9
lethargy 0.9
hypothermia 0.8
hypotonia 0.8
agitation 0.8
weakness 0.7
myalgia 0.6
functional recovery 0.6
arthralgia 0.5
seizures 0.5
acidity 0.4
hypercapnia 0.4
dystonia 0.3
syncope 0.2
dyspnea 0.1
collapse 0.1
constipation 0.0
vomiting -0.0
more...
Drug
Lysine hydrochloride 11.7
Carboxyatractyloside 8.5
Midostaurin 7.3
Fennel 7.3
citric acid 7.0
1,8-Cineole 6.9
Tween 40 6.7
NADH 6.5
Rasburicase 6.3
Florfenicol 6.1
Lead acetate 6.0
C3H8 5.5
Kaolin 5.4
Citric acid 5.3
Clofibrate 5.2
Lactase 5.2
ID2 5.2
Palmitoyl 5.1
Premarin 5.1
Copaxone 5.0
Depo-Provera 5.0
Guanidine 4.9
anti-CD33 4.9
Guanidine 4.9
Artesunate 4.9
SMP 4.7
CTT 4.6
Liraglutide 4.6
MEA 4.5
Maltose 4.5
Glycerol 4.5
Emodin 4.4
CSI 4.4
FAD 4.4
Emodin 4.2
Fructose 4.0
Kainic acid 4.0
ascorbate 3.8
Capsicum 3.8
MgSO4 3.7
more...
Enzyme
trihydroxypterocarpan dimethylallyltransferase 13.3
EC 1.1.1.98 13.3
isocitrate dehydrogenase 13.3
isocitrate dehydrogenase 13.1
PH1722 12.3
gamma-lactonase 12.3
STK3 11.9
PEP phosphatase 11.5
homoisocitrate dehydrogenase 11.1
tartrate dehydrogenase 11.0
formyltetrahydrofolate deformylase 11.0
glycerophosphate phosphatase 10.5
EC 2.7.7.42 10.5
oxoglutarate dehydrogenase 10.3
alpha-ketoglutarate dehydrogenase 10.2
malate oxidase 10.1
fumarase 10.0
aconitase 10.0
EC 1.1.1.40 10.0
isocitrate lyase 9.9
malate dehydrogenase 9.9
6-phosphogluconate dehydrogenase 9.8
6-phosphogluconate dehydrogenase 9.8
PdxA 9.6
malate synthase 9.6
EC 1.1.1.39 9.6
gluconate dehydrogenase 9.5
3-isopropylmalate dehydrogenase 9.2
beta-hydroxybutyrate dehydrogenase 9.2
sortase B 9.1
citrate synthase 9.1
glyoxylate reductase 9.0
glyoxylate reductase 9.0
EC 1.1.1.82 9.0
creatinine iminohydrolase 8.9
tripeptidase 8.9
phosphoenolpyruvate synthase 8.9
EC 1.1.1.38 8.9
glycerol 3-phosphate dehydrogenase 8.8
BCKDH 8.8
more...
Compound
Asparagusate 12.3
2-naphthyl laurate 12.3
2-Hydroxyglutarate 12.0
isocitrate 11.4
hydroxyglutarate 10.8
C6H6O7 10.3
Sinulariolide 10.2
K-38 10.0
A 153 10.0
Butylmalonate 10.0
C4H6O6 9.9
L-Lysine monohydrochloride 9.9
1-butanesulfonic acid 9.6
Palmitoyl-L-carnitine 9.5
DEPA 9.4
PDAP 9.4
Meldola's Blue 9.4
NADP 9.3
2-keto-4-hydroxyglutarate 9.2
Canaline 9.2
DEPA 9.0
Meldola's Blue 8.9
2-oxoglutarate 8.8
Sakuranetin 8.7
2-Oxoglutarate 8.7
p-Nitroanisole 8.7
2-oxoadipate 8.6
KI3 8.5
C6H8O7 8.5
oxalacetate 8.4
6-phosphogluconate 8.3
DPN 8.0
Phenylpyruvate 7.9
Glyoxylate 7.9
IDP 7.9
Coumaphos 7.8
OH-M 7.8
Xanthurenic acid 7.8
4-oxobutanoic acid 7.7
dihydroxyacetone-phosphate 7.7
more...