Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.1.1.41 (
isocitrate dehydrogenase
)
3,101
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
isocitrate dehydrogenase
2945
NADP
554
NADPH
402
malate dehydrogenase
385
NAD
367
IDH1
274
glucose-6-phosphate dehydrogenase
262
lactate dehydrogenase
242
citrate synthase
223
IDH2
199
ATP
196
IDH
190
NADH
189
Sep
185
isocitric dehydrogenase
164
NADP+
158
Mol
158
aconitase
149
glutamate dehydrogenase
136
6-phosphogluconate dehydrogenase
124
ADP
113
NAD+
110
aspartate aminotransferase
105
pyruvate kinase
94
alpha-ketoglutarate dehydrogenase
92
superoxide dismutase
89
NADP-dependent isocitrate dehydrogenase
87
catalase
82
pyruvate dehydrogenase
81
glutathione reductase
79
fumarase
77
hexokinase
73
alkaline phosphatase
71
TCA
70
phosphofructokinase
66
alanine aminotransferase
65
p53
63
GSH
63
ATPase
60
AMP
59
more...
Disease
cancer
339
tumor
302
glioma
242
glioblastoma
139
acute myeloid leukemia
131
GSH
63
brain tumor
56
tumorigenesis
49
glioblastoma multiforme
41
astrocytoma
37
leukemia
34
oligodendroglioma
33
cold
31
carcinogenesis
31
diabetes
27
carcinoma
26
SDS
24
tumor progression
22
ATRX
21
obesity
20
Glioblastoma
20
ischemia
18
melanoma
18
tumor growth
17
chondrosarcoma
17
breast cancer
16
myelodysplastic syndrome
15
Mycobacterium
15
depression
14
anaplastic astrocytoma
14
myocardial infarction
14
hepatocellular carcinoma
13
pheochromocytoma
12
thalassemia
12
ICD
12
mole
12
metastases
12
fatty liver
11
BDB
11
mole
11
more...
Symptom
starvation
21
exhaustion
11
seizures
11
weakness
6
headache
5
nausea
5
anesthesia
4
vomiting
3
collapse
3
hypothermia
3
fatigue
3
dyspnea
3
pain
3
functional recovery
2
diarrhea
2
agitation
2
cough
2
flushing
2
acidity
2
Spots
2
nausea and vomiting
2
numbness
1
asthenia
1
constipation
1
Decreased activity
1
Central post-stroke pain
1
hyperoxia
1
Gasping
1
oliguria
1
hunger
1
hypercapnia
1
tremor
1
twitching
1
thinning
1
shortness of breath
1
blurred vision
1
eds
1
ataxia
1
Anoxia
1
lethargy
1
more...
Drug
NADH
194
citric acid
119
lysine
52
ascorbate
32
ROS
13
Gel
12
FAD
11
vitamin E
9
Adriamycin
6
Leaf
5
Glycerol
5
Cardiovasc
4
Glutathione
4
Asn
4
MAP
4
EE2
4
ABC
3
Capsicum
3
L-tyrosine
3
Nitric Oxide
3
NH3
3
Dermatol
3
Fructose
3
lactose
3
Ethanol
3
Clofibrate
2
Bevacizumab
2
Tween 40
2
Frontal
2
ROC
2
Citric acid
2
ETS
2
Acacia
2
Depo-Provera
2
Angiotensin II
2
Rasburicase
2
MgSO4
2
ADR
2
Kenyan
2
MDS
2
more...
Enzyme
isocitrate dehydrogenase
3101
isocitrate dehydrogenase
2960
malate dehydrogenase
432
glucose-6-phosphate dehydrogenase
323
succinate dehydrogenase
272
lactate dehydrogenase
270
citrate synthase
233
aconitase
172
alpha-ketoglutarate dehydrogenase
151
glutamate dehydrogenase
141
glutamate dehydrogenase
140
glutamate dehydrogenase
138
6-phosphogluconate dehydrogenase
127
6-phosphogluconate dehydrogenase
127
aspartate aminotransferase
120
fumarase
116
pyruvate dehydrogenase
107
superoxide dismutase
102
isocitrate lyase
95
pyruvate kinase
94
alanine aminotransferase
90
catalase
87
pyruvate dehydrogenase
82
pyruvate dehydrogenase
81
glutathione reductase
81
hexokinase
73
alkaline phosphatase
72
ATPase
71
phosphofructokinase
70
diaphorase
60
glutathione peroxidase
59
phosphoenolpyruvate carboxykinase
59
phosphoenolpyruvate carboxykinase
58
acid phosphatase
57
phosphoenolpyruvate carboxykinase
57
cytochrome oxidase
52
alcohol dehydrogenase
50
phosphoglucose isomerase
50
aldolase
49
pyruvate carboxylase
48
more...
Compound
NADP
714
NAD
476
isocitrate
446
NADPH
410
NADPH
402
NAD
367
glucose
364
2-oxoglutarate
331
DNA
268
phosphate
262
oxygen
247
Dec
203
ATP
196
NADH
194
glutamate
175
acetate
175
hydroxyglutarate
167
ADP
116
ADP
113
ADP
113
nitrogen
110
nicotinamide
106
Clin
93
pentose
89
pentose
89
pentose
89
pentose
89
calcium
83
glutamine
75
TCA
72
glycerol
71
water
69
GSH
68
GSH
68
alanine
65
sodium
65
lysine
61
AMP
60
CO2
59
acetyl-CoA
57
more...