Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.1.1.41 (isocitrate dehydrogenase)
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Human Gene/Protein
6-phosphogluconate dehydrogenase, decarboxylating 13.3
isocitrate dehydrogenase 13.3
H-IDH gamma 13.3
actin-related protein T2 13.3
CDH14 13.3
isocitric dehydrogenase 13.3
NAD-IDH 12.7
NADP+-specific isocitrate dehydrogenase 12.5
outer dense fiber protein 2 12.3
ME2 protein 12.3
H3 histone, family 3A 12.3
flavoprotein-linked monooxygenase 12.3
cholinergic receptor, nicotinic, delta polypeptide 12.3
WD repeat and FYVE domain containing 3 12.3
60S ribosomal protein L23 12.3
ATL-derived PMA-responsive peptide 12.3
NADH dehydrogenase flavoprotein 1 12.3
H-IDH alpha 12.3
cadherin 18, type 2 12.3
IDH3A 11.9
IDH3B 11.9
NADP-dependent isocitrate dehydrogenase 11.8
Glucose-6-phosphate 1-dehydrogenase 11.7
D-2-hydroxyglutarate dehydrogenase 11.6
tubulin alpha-1 chain 11.5
NAD+-isocitrate dehydrogenase 11.4
ATP synthase gamma chain 11.3
myosin-Ic 11.3
ACTIN-2 11.3
IDH3G 11.3
PECI 11.3
NADP+-dependent isocitrate dehydrogenase 11.2
IDH2 11.2
actin-related protein 6 11.0
translocon-associated protein delta 11.0
aconitate hydratase 10.9
sentrin/SUMO-specific protease 10.9
IDH 10.8
alpha thalassemia/mental retardation syndrome X-linked 10.8
UL16-binding protein 3 10.7
FIL1 10.7
IDH1 10.7
NADK 10.6
alpha-ketoglutarate dehydrogenase 10.5
POLE1 10.5
phosphoglucomutase 2 10.5
PICD 10.5
Nucleoside diphosphokinase 10.5
Isocitrate dehydrogenase 10.5
IDH1 protein 10.5
ADHFE1 10.3
heterogeneous nuclear ribonucleoprotein A3 10.3
additional sex combs like 1 10.3
60S acidic ribosomal protein P0 10.3
aconitase 2 10.2
Adenosylhomocysteinase 10.2
mannose phosphate isomerase 10.1
malate dehydrogenase 10.1
fumarase 10.0
decarboxylating 10.0
OTUD6B 10.0
Transgelin-2 10.0
ATP synthase subunit alpha 9.9
fumarate hydratase 9.9
aconitase 9.9
phosphorylase, glycogen 9.9
6-phosphogluconate dehydrogenase 9.8
uridine-cytidine kinase 2 9.7
NDUFA4L2 9.7
glucose-6-phosphate 1-dehydrogenase 9.7
NADP 9.6
PSA2 9.6
TEGT 9.6
ropporin 9.6
ribosomal protein L36 9.6
Aconitase 9.6
BDB 9.5
NAD(+) kinase 9.5
peptidase D 9.5
gCap39 9.5
2-oxoglutarate dehydrogenase 9.4
DECR1 9.4
aminoacylase 1 9.3
secreted protein, acidic, cysteine-rich 9.3
succinyl coenzyme A synthetase 9.3
BRAP2 9.3
cytosolic malate dehydrogenase 9.2
Fms-related tyrosine kinase 3 9.2
PRKAG1 9.2
AVEN 9.2
PSA5 9.2
NADP+ 9.2
NADPH2 9.2
Delta-aminolevulinic acid dehydratase 9.2
VDAC-2 9.2
NADP+-dependent malic enzyme 9.2
IFI30 9.2
inhibitor of DNA binding 3 9.1
Chloride intracellular channel protein 1 9.1
GPI1 9.1
PGM5 9.1
citrate synthase 9.1
ELTD1 9.0
KYNU 9.0
transformation/transcription domain-associated protein 9.0
proteasome subunit alpha 9.0
NADP-malic enzyme 9.0
semaphorin 3E 8.9
squamous cell carcinoma antigen 1 8.9
acyl-protein thioesterase 8.9
H3F3A 8.9
isocitrate dehydrogenase 1 8.9
very long-chain acyl-CoA synthetase 8.9
3-hydroxybutyrate dehydrogenase 8.9
ATP synthase subunit beta 8.8
myosin regulatory light chain 2 8.8
SLC25A19 8.8
PRKACB 8.8
CRTAM 8.8
MAPK8IP1 8.8
Citrate synthase 8.8
oxoglutarate 8.8
NADP-ME 8.8
Malic enzyme 8.8
nicotinamide nucleotide transhydrogenase 8.7
glucose-6-phosphate dehydrogenase 8.7
mitochondrial malate dehydrogenase 8.7
G3PD 8.7
beta4Gal-T1 8.7
keratin type II 8.7
ALFY 8.7
phosphoglucomutase 1 8.6
Acetyl-CoA synthetase 8.6
COX8 8.6
CMP kinase 8.6
AK3 8.6
vacuolar proton-ATPase 8.6
gamma-glutamyl cyclotransferase 8.6
ATRX protein 8.5
succinate dehydrogenase flavoprotein subunit 8.5
Methylguanine-DNA methyltransferase 8.5
phosphofructokinase 1 8.5
Gamma-interferon-inducible lysosomal thiol reductase 8.5
integrin-linked kinase 1 8.4
ACON 8.4
ALKBH2 8.4
ZIP5 8.4
glycine dehydrogenase 8.4
ENOX1 8.4
pyruvate carboxylase 8.4
OGDH 8.4
CCE1 8.4
dimethylarginine dimethylaminohydrolase 1 8.4
F1 beta subunit 8.4
WDFY3 8.4
glutamate dehydrogenase 1 8.4
ATRX 8.4
L2HGDH 8.3
FUBP1 8.3
14-3-3 epsilon protein 8.3
ARHGDIB 8.3
RPS12 8.3
TDAG8 8.3
glutamate dehydrogenase 8.3
DDAH-1 8.3
PDHB 8.3
ribosomal protein L22 8.3
RPL22 8.2
DNA directed 8.2
Acetoacetyl-CoA thiolase 8.2
methylenetetrahydrofolate dehydrogenase 1 8.2
ATP synthase subunit 6 8.2
CAD protein 8.2
serine threonine protein kinase 8.2
phosphoglyceromutase 8.2
Malate dehydrogenase 8.1
phosphatidylethanolamine-binding protein 4 8.1
NAD-ME 8.1
FCER1G 8.1
glutamic dehydrogenase 8.1
G6PDH 8.1
nucleoside phosphorylase 8.1
ST20 8.1
cystatin M 8.1
Acylphosphatase 8.1
HOXA2 8.1
acetyl-CoA synthetase 8.0
MDH1 8.0
SLC41A1 8.0
LEU1 8.0
PGDH 8.0
PRDX5 8.0
PRKCQ 8.0
PDHC 8.0
UQCRC2 7.9
tropomyosin 3 7.9
H3F3B 7.9
IDP 7.9
phosphoglycolate phosphatase 7.9
adenylate kinase 1 7.9
eukaryotic protein kinase 7.9
KDM4B 7.9
3-hydroxyisobutyrate dehydrogenase 7.9
Phosphoglucomutase 7.9
MDH2 7.9
citrate transport protein 7.9
Rho GDP dissociation inhibitor alpha 7.9
phosphoglucose isomerase 7.9
6PGD 7.8
Beta-tubulin 7.8
PRAK 7.8
myosin light chain 3 7.8
electron transfer flavoprotein-ubiquinone oxidoreductase 7.8
hydroxypyruvate reductase 7.8
methylmalonate-semialdehyde dehydrogenase 7.8
MYH2 7.8
ASCI 7.8
carboxylating 7.7
Carnitine palmitoyltransferase I 7.7
NAD-malic enzyme 7.7
sorbitol dehydrogenase 7.7
pyruvate dehydrogenase 7.7
fructose 1,6-bisphosphatase 7.7
ACO2 7.7
DAPK2 7.7
ATP citrate lyase 7.7
Succinic semialdehyde dehydrogenase 7.7
ecotropic viral integration site 1 7.7
C-MET 7.7
phosphofructokinase 7.6
phosphoenolpyruvate carboxylase 7.6
KIF2C 7.6
succinic semialdehyde dehydrogenase 7.6
ribosomal protein S5 7.6
APT1 7.6
eIF3g 7.6
NDUFB8 7.6
phosphoglycerate mutase 7.6
transgelin 2 7.6
mitochondrial aconitase 7.6
NAD 7.6
glycolate oxidase 7.6
CRISP1 7.5
pyruvate kinase 7.5
prohibitin 7.5
sirtuin 3 7.5
peroxiredoxin 4 7.5
PEPA 7.5
IGLV 7.5
6-phosphofructokinase 7.5
cation dependent 7.5
NAD+ 7.5
MDH 7.5
MYBL1 7.5
SUCLA2 7.5
Aldolase 7.5
TPN 7.5
ADH4 7.5
PFL 7.4
NAGK 7.4
CBR3 7.4
tropomyosin 1 7.4
leiomyomatosis and renal cell cancer 7.4
NADP-dependent malic enzyme 7.4
MKS1 7.4
BCKDH 7.4
ARAF 7.4
methylguanine-DNA methyltransferase 7.4
15-PGDH 7.4
K74 7.4
NADH dehydrogenase 7.4
glutamate pyruvate transaminase 7.4
NADPH 7.4
GGTA1 7.4
nicotinic acid phosphoribosyltransferase 7.4
Glucose-6-phosphate dehydrogenase 7.4
NAD kinase 7.3
adenosine monophosphate deaminase 7.3
LeuRS 7.3
GDH2 7.3
liver phosphofructokinase 7.3
MutY homolog 7.3
CPX 7.3
CN2 7.3
lactate dehydrogenase A 7.3
SIX6 7.3
ARF7 7.3
Gamma-glutamyltransferase 7.3
ACVR2A 7.3
PFKP 7.3
Annexin A3 7.3
ACL 7.3
ACO 7.3
Pyruvate carboxylase 7.3
Rieske Fe-S protein 7.3
collapsin response mediator protein 2 7.3
VIL 7.2
malectin 7.2
PRDX2 7.2
succinate semialdehyde dehydrogenase 7.2
TCA 7.2
Pyruvate dehydrogenase 7.2
RB1CC1 7.2
isoform a 7.2
lipoamide dehydrogenase 7.2
aldolase A 7.2
triosephosphate isomerase 7.2
NADH diaphorase 7.2
HSP90AB1 7.2
ERp5 7.2
UCK2 7.2
hexokinase 7.2
histone H3.3 7.2
glycerol-3-phosphate dehydrogenase 7.2
Succinic dehydrogenase 7.2
PFKL 7.2
phosphoenolpyruvate carboxykinase 1 7.2
CMAH 7.2
ribosomal protein P0 7.2
SIRT3 7.1
more...
Disease
adult brainstem glioma 12.3
Oligoastrocytoma 11.7
Oligoastrocytoma 11.7
adult pilocytic astrocytoma 10.5
ovarian mixed germ cell tumor 10.2
partial trisomy 2q 10.0
BDB 10.0
Anaplastic oligodendroglioma 9.4
Tanycytic ependymoma 9.4
Diffuse astrocytoma 9.4
Oligodendroglioma 9.3
Periosteal chondroma 9.2
Coxiella infection 9.0
Gliosarcoma 8.9
Waldenstrom's disease 8.9
ATRX 8.4
Withdrawal bleeding 8.2
adult brain tumor 7.8
Herpetosoma 7.7
Maffucci's syndrome 7.7
oligodendroglioma 7.6
RAEB-2 7.6
mixed gliomas 7.4
CPX 7.3
giant cell glioblastoma 7.3
refractory cytopenia with multilineage dysplasia 7.0
FAB M1 6.9
anaplastic astrocytoma 6.9
angioimmunoblastic T-cell lymphoma 6.7
enchondromatosis 6.7
gliosarcoma 6.6
AT/RT 6.5
AML progression 6.5
glioma 6.3
Hepatocarcinogenesis 6.3
glioblastoma 6.3
enchondroma 6.3
embryonal tumor 6.2
Glioblastoma 6.1
syndrome X 6.1
Chondrosarcoma 6.1
Chondrosarcoma 6.1
DIA 6.0
Cholangiocarcinoma 6.0
Cholangiocarcinoma 5.9
adult AML 5.8
chondromatosis 5.8
Sertoli-Leydig cell tumor 5.8
Sertoli-Leydig cell tumor 5.8
Crabs 5.8
astrocytoma 5.7
GS2 5.7
Middle cerebral artery occlusion 5.6
brain tumor 5.6
glioblastoma multiforme 5.5
Endometrium 5.5
Endometrium 5.5
vitamin B6 deficiency 5.5
MPE 5.5
drug-induced hepatitis 5.3
chondrosarcoma 5.3
RSI 5.3
HBD 5.3
hypoglycemic coma 5.3
acute myeloid leukemia 5.3
GS1 5.2
brain cancer 5.1
Chimera 5.1
KNO 5.0
chondrolysis 5.0
Copper deficiency 5.0
biliary tract cancer 4.9
glutaric aciduria 4.9
cancer relapse 4.9
caruncle 4.8
cerebral thrombosis 4.8
PMS 4.7
PDC 4.7
kwashiorkor 4.6
FDH 4.6
propionic acidemia 4.6
Refsum disease 4.6
ASAT 4.6
Reye's syndrome 4.5
MRD 4.5
Malignant transformation 4.5
leukemogenesis 4.5
ependymoma 4.5
Rosenthal 4.4
testicular seminoma 4.4
LIP 4.4
pediatric AML 4.3
Diaphragm 4.3
Mendelian disorders 4.3
chondroblastoma 4.3
Condensation 4.2
craniopharyngioma 4.2
refractory anemia 4.1
MVA 4.1
hyperphenylalaninemia 4.1
PTD 4.1
GSH 4.1
opisthorchiasis 4.1
tyrosinemia 4.1
hyperbilirubinemia 4.0
PGA 4.0
Farber 4.0
PCC 4.0
G6PD deficiency 3.9
RAEB 3.9
ganglioglioma 3.9
methylmalonic acidemia 3.9
alcoholic hepatitis 3.8
PNET 3.8
viral pneumonia 3.8
erythroblastosis 3.8
Q fever 3.8
ADH 3.8
COL2A1 3.8
Hepatotoxicity 3.8
APL 3.8
ICD 3.7
PDR 3.7
gallbladder cancer 3.7
chondroma 3.7
L. infantum 3.7
MRS 3.7
APL 3.7
anaplastic thyroid cancer 3.7
Neoplasms 3.7
generalized seizure 3.6
paraganglioma 3.6
giardiasis 3.6
thalassemia 3.6
MDI 3.6
metritis 3.6
intracranial tumors 3.5
SCS 3.5
hyperoxaluria 3.5
hematologic malignancies 3.5
vitamin E deficiency 3.5
hemangioblastoma 3.5
AS1 3.5
homocystinuria 3.4
premenstrual syndrome 3.4
minimal residual disease 3.4
tularemia 3.4
trisomy 8 3.4
myelodysplastic syndrome 3.4
Testes 3.4
Li-Fraumeni syndrome 3.4
Phenylketonuria 3.3
gynecologic cancer 3.3
ganglioneuroma 3.3
primary myelofibrosis 3.3
chondrodysplasia 3.3
protein deficiency 3.3
GCE 3.3
CNS tumors 3.3
ICT 3.2
chlorosis 3.2
rickets 3.2
oligospermia 3.2
methemoglobinemia 3.2
alkalosis 3.2
PER 3.2
DDD 3.2
stromal tumors 3.1
Colon cancer 3.1
PPP 3.1
tumorigenesis 3.1
tumor initiation 3.1
iron deficiency 3.1
alcoholic fatty liver 3.1
LAP 3.1
MDS 3.1
pheochromocytoma 3.1
T-cell lymphoma 3.1
essential thrombocythemia 3.1
primary central nervous system lymphoma 3.0
metabolic disorder 3.0
tubular necrosis 3.0
Appendix 3.0
Appendix 3.0
Appendix 3.0
HSP 3.0
EMA 3.0
fatty liver 3.0
primitive neuroectodermal tumor 3.0
FTC 3.0
metachromatic leukodystrophy 3.0
canker 3.0
spotted fever 3.0
T-cell lymphomas 2.9
enzyme deficiency 2.9
APL 2.9
Pulmonary arterial hypertension 2.9
chemical carcinogenesis 2.9
achondroplasia 2.9
INS 2.8
ATM 2.8
DES 2.8
multiple endocrine neoplasia 2.7
gastrointestinal stromal tumor 2.7
Robin 2.7
uveal melanoma 2.7
acute promyelocytic leukemia 2.7
primitive neuroectodermal tumor 2.7
mental retardation 2.7
mental retardation 2.7
paroxysmal nocturnal hemoglobinuria 2.7
plant disease 2.7
AIN 2.7
Wells 2.7
mole 2.7
endometrial hyperplasia 2.6
congenital disorder 2.6
hepatitis A 2.6
Pineal 2.6
folate deficiency 2.6
hyperlipoproteinemia 2.6
metabolic alkalosis 2.6
aggressiveness 2.5
mole 2.5
Dependence 2.5
fibrosarcoma 2.5
tumor progression 2.5
Sarcoma 2.5
Sarcoma 2.5
Leukemia 2.4
carcinoma of the cervix 2.4
Dissociation 2.4
pituitary adenoma 2.4
TAM 2.4
ketosis 2.4
FAS 2.3
NPC 2.3
carcinogenesis 2.3
Friedreich's ataxia 2.3
SDS 2.3
Dermal 2.3
osteoma 2.3
IVA 2.3
carcinoma of the breast 2.3
acute tubular necrosis 2.2
EPI 2.2
ALD 2.2
AGS 2.2
primary tumor 2.2
proliferative diabetic retinopathy 2.2
SCT 2.2
tumor 2.2
left ventricular failure 2.2
glomerulopathy 2.1
tumor vasculature 2.1
neoplastic transformation 2.0
Sweet 2.0
Thymus 2.0
Thymus 2.0
Thymus 2.0
idiopathic dilated cardiomyopathy 2.0
renal ischemia 2.0
diplopia 2.0
myeloproliferative disorders 2.0
disorientation 2.0
sarcoma 2.0
malignant fibrous histiocytoma 2.0
heavy drinking 2.0
trisomy 2.0
hyperlipidemia 2.0
wasting 1.9
optic neuritis 1.9
MTS 1.9
hypoparathyroidism 1.9
developmental delay 1.9
leukemia 1.9
residual disease 1.9
epididymis 1.9
carcinoma of the breast 1.9
B-cell lymphoma 1.9
retinopathy of prematurity 1.9
emotional stress 1.9
thyroid cancer 1.8
muscular dystrophy 1.8
ACP 1.8
fallopian tube 1.8
cold 1.8
HCC 1.8
PAF 1.8
acute leukemia 1.8
Brown 1.7
metastatic melanoma 1.7
cholestasis 1.7
fibroma 1.7
osteomalacia 1.7
CAP 1.7
hyperkeratosis 1.7
phenylketonuria 1.7
cancer 1.7
hypothyroidism 1.7
leishmaniasis 1.7
filariasis 1.7
hyperhomocysteinemia 1.7
testicular cancer 1.6
hyperglycemia 1.6
rash 1.6
ICP 1.6
NOD 1.6
infectious mononucleosis 1.6
polycythemia vera 1.6
seminal vesicles 1.6
cerebral ischemia 1.6
Nonalcoholic fatty liver 1.6
NS3 1.6
tumor growth 1.6
hyperthyroidism 1.6
Mycobacterium 1.6
thyroiditis 1.5
gingivitis 1.5
colon cancer 1.5
more...
Symptom
Central post-stroke pain 8.5
Gasping 7.4
Spots 5.5
Decreased activity 4.3
Anoxia 4.2
neurological disability 3.5
eds 3.3
decreased appetite 3.1
starvation 3.1
exhaustion 3.0
nasal discharge 2.9
hypocapnia 2.6
oliguria 2.5
twitching 2.3
blurred vision 2.3
asthenia 2.0
flushing 1.7
nausea 1.1
nausea and vomiting 1.1
numbness 1.0
shortness of breath 1.0
hyperoxia 1.0
hunger 0.9
lethargy 0.9
hypothermia 0.8
hypotonia 0.8
agitation 0.8
weakness 0.7
myalgia 0.6
functional recovery 0.6
arthralgia 0.5
seizures 0.5
acidity 0.4
hypercapnia 0.4
dystonia 0.3
syncope 0.2
dyspnea 0.1
collapse 0.1
constipation 0.0
vomiting -0.0
headache -0.1
thinning -0.1
cough -0.2
ataxia -0.6
fatigue -0.7
tremor -0.8
anesthesia -1.4
diarrhea -1.5
pain -3.1
Drug
Lysine hydrochloride 11.7
Carboxyatractyloside 8.5
Midostaurin 7.3
Fennel 7.3
citric acid 7.0
1,8-Cineole 6.9
Tween 40 6.7
NADH 6.5
Rasburicase 6.3
Florfenicol 6.1
Lead acetate 6.0
C3H8 5.5
Kaolin 5.4
Citric acid 5.3
Clofibrate 5.2
Lactase 5.2
ID2 5.2
Palmitoyl 5.1
Premarin 5.1
Copaxone 5.0
Depo-Provera 5.0
Guanidine 4.9
anti-CD33 4.9
Guanidine 4.9
Artesunate 4.9
SMP 4.7
CTT 4.6
Liraglutide 4.6
MEA 4.5
Maltose 4.5
Glycerol 4.5
Emodin 4.4
CSI 4.4
FAD 4.4
Emodin 4.2
Fructose 4.0
Kainic acid 4.0
ascorbate 3.8
Capsicum 3.8
MgSO4 3.7
Adriamycin 3.7
L-tyrosine 3.7
Acacia 3.7
Xanthium 3.6
Nitric Oxide 3.6
Bevacizumab 3.5
Adenosine triphosphate 3.5
Sodium nitroprusside 3.4
ADR 3.3
Frontal 3.3
CTC 3.3
MDS 3.2
lysine 3.2
Gel 3.1
Arsenic trioxide 3.0
CTC 3.0
ETS 3.0
Honey 3.0
Glutathione 2.9
ROS 2.8
GEO 2.7
Coral 2.7
Kenyan 2.6
Parkin 2.5
Parkin 2.5
EE2 2.4
vitamin E 2.4
EPI 2.3
DHT 2.2
DHT 2.2
CDP 2.1
NH3 2.1
pyridoxal phosphate 2.0
Angiotensin II 2.0
Alliance 1.9
ETA 1.9
Alanine 1.9
Asn 1.8
ABC 1.8
Growth hormone 1.8
Growth hormone 1.8
Ethanol 1.7
MRC 1.6
niacin 1.4
ROC 1.4
p75 1.4
MAP 1.4
Leaf 1.2
G-CSF 1.0
ICI 0.9
lactose 0.9
Mutagen 0.8
Indomethacin 0.7
CaCl2 0.7
CaCl2 0.7
CaCl2 0.6
DNase I 0.3
CTX 0.0
TiO2 -0.1
ZnO -0.4
Nephron -0.8
CSF -1.6
Cardiovasc -2.3
Dermatol -3.1
Enzyme
EC 1.1.1.98 13.3
isocitrate dehydrogenase 13.3
trihydroxypterocarpan dimethylallyltransferase 13.3
isocitrate dehydrogenase 13.1
gamma-lactonase 12.3
PH1722 12.3
STK3 11.9
PEP phosphatase 11.5
homoisocitrate dehydrogenase 11.1
formyltetrahydrofolate deformylase 11.0
tartrate dehydrogenase 11.0
glycerophosphate phosphatase 10.5
EC 2.7.7.42 10.5
oxoglutarate dehydrogenase 10.3
alpha-ketoglutarate dehydrogenase 10.2
malate oxidase 10.1
fumarase 10.0
aconitase 10.0
EC 1.1.1.40 10.0
isocitrate lyase 9.9
malate dehydrogenase 9.9
6-phosphogluconate dehydrogenase 9.8
6-phosphogluconate dehydrogenase 9.8
PdxA 9.6
malate synthase 9.6
EC 1.1.1.39 9.6
gluconate dehydrogenase 9.5
3-isopropylmalate dehydrogenase 9.2
beta-hydroxybutyrate dehydrogenase 9.2
sortase B 9.1
citrate synthase 9.1
glyoxylate reductase 9.0
glyoxylate reductase 9.0
EC 1.1.1.82 9.0
creatinine iminohydrolase 8.9
tripeptidase 8.9
phosphoenolpyruvate synthase 8.9
EC 1.1.1.38 8.9
glycerol 3-phosphate dehydrogenase 8.8
BCKDH 8.8
prolinase 8.8
glucose-6-phosphate dehydrogenase 8.7
penicillopepsin 8.7
shikimate dehydrogenase 8.7
glutamic dehydrogenase 8.7
succinyl-CoA synthetase 8.6
glycine dehydrogenase 8.6
glycine dehydrogenase 8.6
citrate cleavage enzyme 8.6
citrate lyase 8.5
phytanoyl-CoA hydroxylase 8.5
glycolate dehydrogenase 8.5
phosphoglucomutase 8.5
transhydrogenase 8.4
2-oxoglutarate decarboxylase 8.4
phenylpyruvate decarboxylase 8.4
succinate dehydrogenase 8.4
methylmalonate-semialdehyde dehydrogenase 8.4
glutamate dehydrogenase 8.4
glutamate dehydrogenase 8.4
pyruvate carboxylase 8.3
aryl-alcohol dehydrogenase 8.3
glutamate dehydrogenase 8.3
3-oxoacid CoA-transferase 8.3
2-hydroxyglutarate dehydrogenase 8.2
phosphoglucose isomerase 8.2
glutamate synthase 8.2
phosphomannose isomerase 8.2
L-amino-acid oxidase 8.2
octanol dehydrogenase 8.2
nicotinic acid phosphoribosyltransferase 8.1
N-acetylglucosamine kinase 8.1
glutamate synthase 8.1
octopine dehydrogenase 8.1
3-hydroxyisobutyrate dehydrogenase 8.0
acetate kinase 8.0
NADH kinase 8.0
IMP cyclohydrolase 8.0
glycine dehydrogenase 8.0
acetyl-CoA synthetase 8.0
glycerol-3-phosphate dehydrogenase 7.9
pyruvate dehydrogenase 7.9
pyruvate dehydrogenase 7.9
thiosulfate dehydrogenase 7.9
condensing enzyme 7.9
glutamate synthase 7.8
succinic dehydrogenase 7.8
ribulose 5-phosphate 3-epimerase 7.8
glycerol-3-phosphate dehydrogenase 7.8
CMP-Neu5Ac hydroxylase 7.8
phosphoglycolate phosphatase 7.8
glycolate oxidase 7.6
pyruvate dehydrogenase 7.6
phosphoenolpyruvate carboxylase 7.6
3-hydroxybutyryl-CoA dehydrogenase 7.6
SCS 7.6
sorbitol dehydrogenase 7.6
alanine dehydrogenase 7.6
phosphofructokinase 7.5
pyruvate kinase 7.5
AICAR transformylase 7.5
creatininase 7.5
fumarate reductase 7.5
allantoicase 7.5
MDH 7.5
pyruvate:ferredoxin oxidoreductase 7.5
succinic semialdehyde dehydrogenase 7.4
NADH dehydrogenase 7.4
MDH 7.4
creatinase 7.4
CobB 7.4
triose-phosphate isomerase 7.4
6-phosphogluconate dehydratase 7.3
phosphoglyceromutase 7.3
glucosamine-6-phosphate deaminase 7.2
acetoacetyl-CoA reductase 7.2
aldolase 7.2
fructose 1,6-bisphosphatase 7.2
phosphoenolpyruvate carboxykinase 7.2
hexokinase 7.2
phosphoenolpyruvate carboxykinase 7.1
benzyl alcohol dehydrogenase 7.1
D-amino-acid oxidase 7.1
PDH 7.1
EC 4.4.1.5 7.1
cinnamoyl-CoA reductase 7.1
glutamate mutase 7.1
3-hydroxy-3-methylglutaryl-CoA lyase 7.0
PPDK 7.0
mannitol dehydrogenase 7.0
CMP kinase 7.0
phosphoenolpyruvate carboxykinase 7.0
nucleoside diphosphokinase 7.0
acetoacetyl-CoA thiolase 7.0
esterase D 7.0
3-hydroxyacyl-CoA dehydrogenase 6.9
hydroxypyruvate reductase 6.9
6-phosphogluconolactonase 6.9
adenylate kinase 6.9
pyruvate dehydrogenase phosphatase 6.9
nucleoside hydrolase 6.8
mannitol dehydrogenase 6.8
pyruvate decarboxylase 6.8
isovaleryl-CoA dehydrogenase 6.8
glycine decarboxylase 6.8
homogentisate 1,2-dioxygenase 6.7
hydroxypyruvate reductase 6.7
3-hydroxyacyl-CoA dehydrogenase 6.7
diaphorase 6.7
glycerol-3-phosphate oxidase 6.6
carnitine acetyltransferase 6.6
diaphorase 6.6
phosphoglycerate dehydrogenase 6.6
mutarotase 6.6
lactate dehydrogenase 6.6
nicotinamidase 6.5
DAP II 6.5
ribose-5-phosphate isomerase 6.5
polyphosphatase 6.5
ribokinase 6.5
phosphofructokinase 1 6.5
PHB depolymerase 6.5
PGM 6.5
glutathione reductase 6.4
enolase 6.4
EC 2.7.7.9 6.4
allantoinase 6.4
glucose-6-phosphatase 6.4
prolidase 6.4
phosphoserine aminotransferase 6.4
asparagine synthetase 6.4
15-hydroxyprostaglandin dehydrogenase 6.4
20alpha-hydroxysteroid dehydrogenase 6.3
HOA 6.3
glyceraldehyde-3-phosphate dehydrogenase 6.3
glutamine synthetase 6.3
glyceraldehyde-3-phosphate dehydrogenase 6.3
threonine dehydrogenase 6.3
PWD 6.3
glyceraldehyde-3-phosphate dehydrogenase 6.3
transaldolase 6.3
glyceraldehyde-3-phosphate dehydrogenase 6.3
GABA transaminase 6.3
S-adenosyl-L-homocysteine hydrolase 6.2
methionine adenosyltransferase 6.2
dihydropyrimidinase 6.2
riboflavin synthase 6.2
lipoate acetyltransferase 6.1
lactic acid dehydrogenase 6.1
carbamoylphosphate synthetase 6.1
fatty-acid synthase 6.1
inosine triphosphatase 6.0
alpha-N-acetylgalactosaminidase 6.0
formate dehydrogenase 6.0
formate dehydrogenase 6.0
oxaloacetate decarboxylase 5.9
homocysteine methyltransferase 5.9
ubiquinol-cytochrome c oxidoreductase 5.9
disulfide reductase 5.9
cytochrome oxidase 5.9
17beta-HSD 5.9
xylulokinase 5.9
dCMP deaminase 5.9
formate dehydrogenase 5.8
lysine acetyltransferase 5.8
aspartate aminotransferase 5.8
glyceraldehyde-3-phosphate dehydrogenase 5.8
ornithine aminotransferase 5.8
leucine aminopeptidase 5.8
fructokinase 5.8
glycerol kinase 5.8
transketolase 5.8
alcohol dehydrogenase 5.8
lactate oxidase 5.8
adenylosuccinate lyase 5.8
kynurenine 3-monooxygenase 5.8
complex I 5.7
sucrose synthase 5.7
MTD 5.7
uricase 5.7
argininosuccinate lyase 5.6
aspartase 5.6
adenylosuccinate synthetase 5.6
PTA 5.6
uridyltransferase 5.6
4-epimerase 5.6
NAD+ oxidoreductase 5.6
glutaryl-CoA dehydrogenase 5.6
arginine kinase 5.6
KAT 5.5
acetyl-CoA carboxylase 5.5
acid phosphatase 5.5
CO dehydrogenase 5.5
glycerol dehydrogenase 5.5
lactic acid dehydrogenase 5.5
branched-chain aminotransferase 5.5
acylphosphatase 5.5
glutaminyl-tRNA synthetase 5.5
glycerol dehydrogenase 5.5
guanase 5.5
oxalate oxidase 5.4
3-mercaptopyruvate sulfurtransferase 5.4
acyl-CoA dehydrogenase 5.4
lactic acid dehydrogenase 5.4
phosphomannomutase 5.4
formaldehyde dehydrogenase 5.4
phosphoglycerate kinase 5.4
NADPH-diaphorase 5.4
aldehyde oxidase 5.4
CPR 5.4
ATP synthase 5.4
ClpP 5.3
acyl-CoA synthetase 5.3
nucleotidase 5.3
phosphoribulokinase 5.3
carbonyl reductase 5.3
acyl-CoA dehydrogenase 5.3
xylitol dehydrogenase 5.3
pyruvate oxidase 5.3
pyruvate oxidase 5.2
glutaminase 5.2
proline oxidase 5.2
dehydroascorbate reductase 5.2
methionine synthase 5.2
phosphorylase 5.2
xylitol dehydrogenase 5.2
GalT 5.2
glucokinase 5.2
fumarylacetoacetate hydrolase 5.2
DNA methyltransferase 5.1
serine hydroxymethyltransferase 5.1
alanine aminotransferase 5.1
leucyl-tRNA synthetase 5.1
methionine synthase 5.1
chitin synthase 5.1
thioredoxin reductase 5.1
dimethylarginine dimethylaminohydrolase 5.1
HPI 5.1
proline dehydrogenase 5.1
sortase A 5.1
cysteine synthase 5.0
5'-nucleotidase 5.0
UDP-glucose dehydrogenase 5.0
cystathionine beta-synthase 5.0
peroxiredoxin 5.0
levansucrase 5.0
6-phosphofructo-2-kinase 5.0
aldehyde dehydrogenase 4.9
aldehyde dehydrogenase 4.9
propionyl-CoA carboxylase 4.9
monoacylglycerol lipase 4.9
glucose dehydrogenase 4.9
aldehyde dehydrogenase 4.9
Omi/HtrA2 4.9
propionyl-CoA carboxylase 4.9
aldehyde dehydrogenase 4.9
tryptophanase 4.9
reductoisomerase 4.8
polynucleotide phosphorylase 4.8
guanylate kinase 4.8
threonine deaminase 4.8
nucleotide pyrophosphatase 4.8
nicotinamide phosphoribosyltransferase 4.8
glutathione peroxidase 4.8
PDK1 4.8
aldehyde dehydrogenase 4.7
legumain 4.7
branched-chain alpha-keto acid dehydrogenase 4.7
creatine kinase 4.7
aspartokinase 4.7
methylmalonyl-CoA mutase 4.7
dUTPase 4.7
GLO 4.7
acyl-CoA synthetase 4.6
NAD glycohydrolase 4.6
cruzipain 4.6
IscS 4.6
NQO1 4.5
rubisco 4.5
sulfite oxidase 4.5
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Compound
Asparagusate 12.3
2-naphthyl laurate 12.3
2-Hydroxyglutarate 12.0
isocitrate 11.4
hydroxyglutarate 10.8
C6H6O7 10.3
Sinulariolide 10.2
A 153 10.0
Butylmalonate 10.0
K-38 10.0
C4H6O6 9.9
L-Lysine monohydrochloride 9.9
1-butanesulfonic acid 9.6
Palmitoyl-L-carnitine 9.5
Meldola's Blue 9.4
DEPA 9.4
PDAP 9.4
NADP 9.3
Canaline 9.2
2-keto-4-hydroxyglutarate 9.2
DEPA 9.0
Meldola's Blue 8.9
2-oxoglutarate 8.8
Sakuranetin 8.7
2-Oxoglutarate 8.7
p-Nitroanisole 8.7
2-oxoadipate 8.6
C6H8O7 8.5
KI3 8.5
oxalacetate 8.4
6-phosphogluconate 8.3
DPN 8.0
Phenylpyruvate 7.9
Glyoxylate 7.9
IDP 7.9
Coumaphos 7.8
OH-M 7.8
Xanthurenic acid 7.8
4-oxobutanoic acid 7.7
dihydroxyacetone-phosphate 7.7
alpha-isopropylmalate 7.6
NAD 7.6
NAD 7.5
Methionine sulfoximine 7.5
NADPH 7.4
NADPH 7.4
Malate 7.4
sedoheptulose 7-phosphate 7.3
1-naphthyl acetate 7.3
Trenimon 7.2
Metaproterenol 7.2
Dydrogesterone 7.2
pentose 7.2
pentose 7.2
Potassium dichromate 7.2
pentose 7.1
pentose 7.1
Glycolate 7.1
Malonate 7.1
TET 7.0
TET 7.0
Phytanic acid 7.0
D-Glyceraldehyde 7.0
Phenylglyoxal 7.0
Azoxymethane 6.9
Bromophenol Blue 6.9
Pyruvate kinase 6.9
Azaserine 6.9
MTU 6.8
acetyl-CoA 6.8
itaconic acid 6.7
Sodium deoxycholate 6.7
erythrose-4-phosphate 6.7
Ethionine 6.6
CIT 6.6
2-keto-3-deoxygluconate 6.5
glucose-6-phosphate 6.5
Piperine 6.5
Potassium chloride 6.5
PDH 6.5
NADH 6.5
2,4-pentanedione 6.4
2,4-pentanedione 6.4
2,4-pentanedione 6.4
2,4-pentanedione 6.4
2,4-pentanedione 6.4
2,4-pentanedione 6.4
Mancozeb 6.4
Phosphoserine 6.4
Glucose 6-phosphate 6.4
TCA 6.4
1,2-cyclohexanediamine 6.4
1,2-cyclohexanediamine 6.4
2,4-pentanedione 6.3
2,4-pentanedione 6.3
2,4-pentanedione 6.3
2,4-pentanedione 6.3
2,4-pentanedione 6.3
2,4-pentanedione 6.3
2,4-pentanedione 6.3
S-allylcysteine 6.3
2,4-pentanedione 6.3
succinic acid 6.3
Catalpol 6.3
1H-indene 6.2
PIPES 6.2
PIPES 6.2
PIPES 6.2
DCVC 6.1
nicotinamide 6.1
Lupeol 6.0
Palmitoleic acid 6.0
hexitol 6.0
hexitol 6.0
Ajmaline 6.0
Buthionine sulfoximine 6.0
malic acid 5.9
hexitol 5.9
6-aminonicotinamide 5.9
Dihydroxyacetone 5.9
Coenzyme A 5.9
androst-4-ene-3,17-dione 5.9
DETA 5.8
alcohol dehydrogenase 5.8
fructose-1-phosphate 5.8
WR-1065 5.7
dihydrolipoamide 5.7
2,4-pentanedione 5.7
D-gluconate 5.7
hexose 5.6
hexose 5.6
hexose 5.6
MAK 5.6
Citral 5.6
Norethisterone 5.6
Methyl jasmonate 5.6
Flux 5.6
Diamide 5.6
Chlordecone 5.5
alpha-ketoisocaproate 5.5
(-)-Epigallocatechin 5.4
Coomassie Blue 5.4
Gossypol 5.3
Gossypol 5.3
DMM 5.3
S 1 5.3
Pantothenate 5.3
Lithium chloride 5.3
MAD 5.2
Cyanogen bromide 5.2
succinic acid 5.2
succinic acid 5.2
succinic acid 5.2
succinic acid 5.2
Trimethylamine N-oxide 5.2
NMN 5.2
MoO4 5.1
AAT 5.1
PEP 5.1
Clofibrate 5.1
Isoform 5.1
hexose 5.1
pyrroline-5-carboxylate 5.1
G3P 5.0
Hesperidin 5.0
Premarin 5.0
Glutamate 5.0
palmitoyl-CoA 5.0
ACNU 5.0
Cytochrome c 5.0
CoA 5.0
ADP 4.9
ADP 4.9
Methimazole 4.9
Ethidium bromide 4.9
Daidzein 4.9
glutamine 4.8
2-methoxyphenol 4.8
ADP 4.8
DLT 4.8
malic acid 4.8
malic acid 4.8
RELA 4.8
Pyruvate 4.8
Carnitine 4.7
malic acid 4.7
Propidium iodide 4.7
GPT 4.7
APT 4.7
Temozolomide 4.7
Ornithine 4.6
bromoform 4.6
Naringenin 4.6
PMS 4.6
phenylacetaldehyde 4.6
glutamate 4.6
TGT 4.6
Fumarate 4.6
Morin 4.6
ubiquinol 4.6
Naringenin 4.6
3-methylindole 4.5
DCMU 4.5
Glyphosate 4.5
ornithine 4.5
ornithine 4.5
ornithine 4.5
ornithine 4.5
ornithine 4.5
MEA 4.5
phenylacetaldehyde 4.5
Vanillin 4.5
GSSG 4.4
Pectin 4.4
Maltose 4.4
ETH 4.4
Xylose 4.4
Emodin 4.4
phenylacetaldehyde 4.4
Lactate 4.4
Thyroxine 4.3
alloxan 4.3
FAD 4.3
adenylate 4.3
PHB 4.3
Carnosine 4.3
Actinomycin D 4.3
Valine 4.3
Creatine 4.3
Conjugated linoleic acid 4.3
HOG 4.3
L-carnitine 4.2
CCl4 4.2
PLP 4.2
Rhodamine 123 4.2
Glu-Glu 4.2
Triiodothyronine 4.2
Staurosporine 4.2
3-hydroxybutyric acid 4.2
carbamyl phosphate 4.2
glycerol 4.2
MPP 4.2
Ferulic acid 4.1
Ferulic acid 4.1
Staurosporine 4.1
DMPP 4.1
MPP 4.1
Deoxynivalenol 4.1
Deoxyribonucleic acid 4.1
GSH 4.1
GSH 4.1
Mg2+ 4.1
malonyl-CoA 4.0
Tempol 4.0
manganese 4.0
phosphoserine 4.0
Kainic acid 4.0
Kainic acid 4.0
CDH 4.0
Glyphosate 4.0
IPC 4.0
Propionate 3.9
Fructose 3.9
acetate 3.9
phosphate 3.9
ATP 3.9
Acrolein 3.9
oxalic acid 3.9
Luteolin 3.9
CPT 3.9
Streptomycin 3.9
Dichloroacetate 3.9
Lip 3.9
AMP 3.9
hexadecane 3.9
BOP 3.9
LIN 3.8
DIM 3.8
Uracil 3.8
STZ 3.8
TPP 3.7
Sorbitol 3.7
Uridine 3.7
Bisphenol A 3.7
Bisphenol A 3.7
dicarboxylic acid 3.7
Vitamin D3 3.7
Dithiothreitol 3.7
CCP 3.7
AICAR 3.6
glutamic acid 3.6
glucose 3.6
trifluoroacetic acid 3.6
trifluoroacetic acid 3.6
trifluoroacetic acid 3.6
trifluoroacetic acid 3.6
INT 3.6
Docosahexaenoic acid 3.6
TAA 3.6
Ether 3.6
Brefeldin A 3.6
Premarin 3.6
Brefeldin A 3.6
Starch 3.6
trifluoroacetic acid 3.6
Ether 3.6
Vitamin D3 3.6
CAN 3.6
TBI 3.6
1,3-propanediol 3.5
CCNU 3.5
morpholine 3.5
CIT 3.5
nitrous acid 3.5
MVA 3.5
PGA 3.5
aflatoxin B1 3.5
NBQX 3.5
bis(2-chloroethyl) 3.4
Minocycline 3.4
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