Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.1.1.41 (isocitrate dehydrogenase)
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Human Gene/Protein
CDH14 13.3
H-IDH gamma 13.3
6-phosphogluconate dehydrogenase, decarboxylating 13.3
isocitrate dehydrogenase 13.3
actin-related protein T2 13.3
isocitric dehydrogenase 13.3
NAD-IDH 12.7
NADP+-specific isocitrate dehydrogenase 12.5
60S ribosomal protein L23 12.3
NADH dehydrogenase flavoprotein 1 12.3
ATL-derived PMA-responsive peptide 12.3
cadherin 18, type 2 12.3
WD repeat and FYVE domain containing 3 12.3
H-IDH alpha 12.3
ME2 protein 12.3
H3 histone, family 3A 12.3
outer dense fiber protein 2 12.3
cholinergic receptor, nicotinic, delta polypeptide 12.3
flavoprotein-linked monooxygenase 12.3
IDH3A 11.9
more...
Disease
adult brainstem glioma 12.3
Oligoastrocytoma 11.7
Oligoastrocytoma 11.7
adult pilocytic astrocytoma 10.5
ovarian mixed germ cell tumor 10.2
partial trisomy 2q 10.0
BDB 10.0
Tanycytic ependymoma 9.4
Anaplastic oligodendroglioma 9.4
Diffuse astrocytoma 9.4
Oligodendroglioma 9.3
Periosteal chondroma 9.2
Coxiella infection 9.0
Gliosarcoma 8.9
Waldenstrom's disease 8.9
ATRX 8.4
Withdrawal bleeding 8.2
adult brain tumor 7.8
Herpetosoma 7.7
Maffucci's syndrome 7.7
more...
Symptom
Central post-stroke pain 8.5
Gasping 7.4
Spots 5.5
Decreased activity 4.3
Anoxia 4.2
neurological disability 3.5
eds 3.3
decreased appetite 3.1
starvation 3.1
exhaustion 3.0
nasal discharge 2.9
hypocapnia 2.6
oliguria 2.5
twitching 2.3
blurred vision 2.3
asthenia 2.0
flushing 1.7
nausea 1.1
nausea and vomiting 1.1
numbness 1.0
more...
Drug
Lysine hydrochloride 11.7
Carboxyatractyloside 8.5
Midostaurin 7.3
Fennel 7.3
citric acid 7.0
1,8-Cineole 6.9
Tween 40 6.7
NADH 6.5
Rasburicase 6.3
Florfenicol 6.1
Lead acetate 6.0
C3H8 5.5
Kaolin 5.4
Citric acid 5.3
Clofibrate 5.2
Lactase 5.2
ID2 5.2
Palmitoyl 5.1
Premarin 5.1
Copaxone 5.0
more...
Enzyme
isocitrate dehydrogenase 13.3
EC 1.1.1.98 13.3
trihydroxypterocarpan dimethylallyltransferase 13.3
isocitrate dehydrogenase 13.1
PH1722 12.3
gamma-lactonase 12.3
STK3 11.9
PEP phosphatase 11.5
homoisocitrate dehydrogenase 11.1
tartrate dehydrogenase 11.0
formyltetrahydrofolate deformylase 11.0
glycerophosphate phosphatase 10.5
EC 2.7.7.42 10.5
oxoglutarate dehydrogenase 10.3
alpha-ketoglutarate dehydrogenase 10.2
malate oxidase 10.1
fumarase 10.0
aconitase 10.0
EC 1.1.1.40 10.0
isocitrate lyase 9.9
more...
Compound
2-naphthyl laurate 12.3
Asparagusate 12.3
2-Hydroxyglutarate 12.0
isocitrate 11.4
hydroxyglutarate 10.8
C6H6O7 10.3
Sinulariolide 10.2
Butylmalonate 10.0
K-38 10.0
A 153 10.0
C4H6O6 9.9
L-Lysine monohydrochloride 9.9
1-butanesulfonic acid 9.6
Palmitoyl-L-carnitine 9.5
PDAP 9.4
DEPA 9.4
Meldola's Blue 9.4
NADP 9.3
2-keto-4-hydroxyglutarate 9.2
Canaline 9.2
more...