Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.1.1.41 (isocitrate dehydrogenase)
3,101 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
isocitrate dehydrogenase 2945
NADP 554
NADPH 402
malate dehydrogenase 385
NAD 367
IDH1 274
glucose-6-phosphate dehydrogenase 262
lactate dehydrogenase 242
citrate synthase 223
IDH2 199
ATP 196
IDH 190
NADH 189
Sep 185
isocitric dehydrogenase 164
Mol 158
NADP+ 158
aconitase 149
glutamate dehydrogenase 136
6-phosphogluconate dehydrogenase 124
more...
Disease
cancer 339
tumor 302
glioma 242
glioblastoma 139
acute myeloid leukemia 131
GSH 63
brain tumor 56
tumorigenesis 49
glioblastoma multiforme 41
astrocytoma 37
leukemia 34
oligodendroglioma 33
cold 31
carcinogenesis 31
diabetes 27
carcinoma 26
SDS 24
tumor progression 22
ATRX 21
Glioblastoma 20
more...
Symptom
starvation 21
exhaustion 11
seizures 11
weakness 6
nausea 5
headache 5
anesthesia 4
dyspnea 3
hypothermia 3
pain 3
fatigue 3
collapse 3
vomiting 3
Spots 2
diarrhea 2
cough 2
agitation 2
flushing 2
functional recovery 2
nausea and vomiting 2
more...
Drug
NADH 194
citric acid 119
lysine 52
ascorbate 32
ROS 13
Gel 12
FAD 11
vitamin E 9
Adriamycin 6
Glycerol 5
Leaf 5
Glutathione 4
Asn 4
Cardiovasc 4
MAP 4
EE2 4
lactose 3
Ethanol 3
ABC 3
Nitric Oxide 3
more...
Enzyme
isocitrate dehydrogenase 3101
isocitrate dehydrogenase 2960
malate dehydrogenase 432
glucose-6-phosphate dehydrogenase 323
succinate dehydrogenase 272
lactate dehydrogenase 270
citrate synthase 233
aconitase 172
alpha-ketoglutarate dehydrogenase 151
glutamate dehydrogenase 141
glutamate dehydrogenase 140
glutamate dehydrogenase 138
6-phosphogluconate dehydrogenase 127
6-phosphogluconate dehydrogenase 127
aspartate aminotransferase 120
fumarase 116
pyruvate dehydrogenase 107
superoxide dismutase 102
isocitrate lyase 95
pyruvate kinase 94
more...
Compound
NADP 714
NAD 476
isocitrate 446
NADPH 410
NADPH 402
NAD 367
glucose 364
2-oxoglutarate 331
DNA 268
phosphate 262
oxygen 247
Dec 203
ATP 196
NADH 194
acetate 175
glutamate 175
hydroxyglutarate 167
ADP 116
ADP 113
ADP 113
more...