Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.1.1.41 (
isocitrate dehydrogenase
)
3,101
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
isocitrate dehydrogenase
2945
NADP
554
NADPH
402
malate dehydrogenase
385
NAD
367
IDH1
274
glucose-6-phosphate dehydrogenase
262
lactate dehydrogenase
242
citrate synthase
223
IDH2
199
ATP
196
IDH
190
NADH
189
Sep
185
isocitric dehydrogenase
164
Mol
158
NADP+
158
aconitase
149
glutamate dehydrogenase
136
6-phosphogluconate dehydrogenase
124
more...
Disease
cancer
339
tumor
302
glioma
242
glioblastoma
139
acute myeloid leukemia
131
GSH
63
brain tumor
56
tumorigenesis
49
glioblastoma multiforme
41
astrocytoma
37
leukemia
34
oligodendroglioma
33
cold
31
carcinogenesis
31
diabetes
27
carcinoma
26
SDS
24
tumor progression
22
ATRX
21
Glioblastoma
20
more...
Symptom
starvation
21
exhaustion
11
seizures
11
weakness
6
nausea
5
headache
5
anesthesia
4
dyspnea
3
hypothermia
3
pain
3
fatigue
3
collapse
3
vomiting
3
Spots
2
diarrhea
2
cough
2
agitation
2
flushing
2
functional recovery
2
nausea and vomiting
2
more...
Drug
NADH
194
citric acid
119
lysine
52
ascorbate
32
ROS
13
Gel
12
FAD
11
vitamin E
9
Adriamycin
6
Glycerol
5
Leaf
5
Glutathione
4
Asn
4
Cardiovasc
4
MAP
4
EE2
4
lactose
3
Ethanol
3
ABC
3
Nitric Oxide
3
more...
Enzyme
isocitrate dehydrogenase
3101
isocitrate dehydrogenase
2960
malate dehydrogenase
432
glucose-6-phosphate dehydrogenase
323
succinate dehydrogenase
272
lactate dehydrogenase
270
citrate synthase
233
aconitase
172
alpha-ketoglutarate dehydrogenase
151
glutamate dehydrogenase
141
glutamate dehydrogenase
140
glutamate dehydrogenase
138
6-phosphogluconate dehydrogenase
127
6-phosphogluconate dehydrogenase
127
aspartate aminotransferase
120
fumarase
116
pyruvate dehydrogenase
107
superoxide dismutase
102
isocitrate lyase
95
pyruvate kinase
94
more...
Compound
NADP
714
NAD
476
isocitrate
446
NADPH
410
NADPH
402
NAD
367
glucose
364
2-oxoglutarate
331
DNA
268
phosphate
262
oxygen
247
Dec
203
ATP
196
NADH
194
acetate
175
glutamate
175
hydroxyglutarate
167
ADP
116
ADP
113
ADP
113
more...