Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.1.1.41 (isocitrate dehydrogenase)
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Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
isocitrate dehydrogenase 0.949
isocitric dehydrogenase 0.051
IDH2 0.014
IDH1 0.014
NADP 0.014
malate dehydrogenase 0.013
IDH 0.011
NADP-dependent isocitrate dehydrogenase 0.010
aconitase 0.004
alpha-ketoglutarate dehydrogenase 0.004
citrate synthase 0.004
6-phosphogluconate dehydrogenase 0.004
glucose-6-phosphate dehydrogenase 0.004
NAD-IDH 0.003
NADP+ 0.003
fumarase 0.003
NADP+-specific isocitrate dehydrogenase 0.003
NAD 0.002
NADPH 0.002
decarboxylating 0.002
aconitate hydratase 0.001
glutamate dehydrogenase 0.001
Isocitrate dehydrogenase 0.001
fumarate hydratase 0.001
NADP+-dependent isocitrate dehydrogenase 0.001
IDH3A 0.001
2-oxoglutarate dehydrogenase 0.001
lactate dehydrogenase 0.001
NAD+-isocitrate dehydrogenase 0.001
NAD+ 0.001
IDH3B 0.001
D-2-hydroxyglutarate dehydrogenase 0.001
pyruvate kinase 0.001
pyruvate dehydrogenase 0.001
NADH 0.001
pyruvate carboxylase 0.001
isocitrate dehydrogenase 1 0.000
CDH14 0.000
actin-related protein T2 0.000
H-IDH gamma 0.000
6-phosphogluconate dehydrogenase, decarboxylating 0.000
phosphofructokinase 0.000
TCA 0.000
hexokinase 0.000
cholinergic receptor, nicotinic, delta polypeptide 0.000
WD repeat and FYVE domain containing 3 0.000
H-IDH alpha 0.000
ATL-derived PMA-responsive peptide 0.000
ME2 protein 0.000
NADH dehydrogenase flavoprotein 1 0.000
flavoprotein-linked monooxygenase 0.000
H3 histone, family 3A 0.000
outer dense fiber protein 2 0.000
60S ribosomal protein L23 0.000
cadherin 18, type 2 0.000
tubulin alpha-1 chain 0.000
alpha thalassemia/mental retardation syndrome X-linked 0.000
mannose phosphate isomerase 0.000
BDB 0.000
Aconitase 0.000
Glucose-6-phosphate 1-dehydrogenase 0.000
aspartate aminotransferase 0.000
Citrate synthase 0.000
ATRX 0.000
sentrin/SUMO-specific protease 0.000
oxoglutarate 0.000
glutathione reductase 0.000
IDH3G 0.000
ACTIN-2 0.000
ATP synthase gamma chain 0.000
IDH1 protein 0.000
PECI 0.000
myosin-Ic 0.000
methylguanine-DNA methyltransferase 0.000
phosphoglucose isomerase 0.000
NADP-malic enzyme 0.000
NADK 0.000
phosphoenolpyruvate carboxylase 0.000
cytosolic malate dehydrogenase 0.000
mitochondrial malate dehydrogenase 0.000
NADH dehydrogenase 0.000
translocon-associated protein delta 0.000
actin-related protein 6 0.000
H3F3A 0.000
phosphoglucomutase 2 0.000
POLE1 0.000
ACL 0.000
UL16-binding protein 3 0.000
FIL1 0.000
aconitase 2 0.000
ATP synthase subunit alpha 0.000
sorbitol dehydrogenase 0.000
PICD 0.000
Nucleoside diphosphokinase 0.000
heterogeneous nuclear ribonucleoprotein A3 0.000
60S acidic ribosomal protein P0 0.000
ADHFE1 0.000
additional sex combs like 1 0.000
cytochrome c oxidase 0.000
peptidase D 0.000
Adenosylhomocysteinase 0.000
3-hydroxybutyrate dehydrogenase 0.000
ADP 0.000
NADPH2 0.000
alcohol dehydrogenase 0.000
Malic enzyme 0.000
acetyl-CoA synthetase 0.000
nicotinamide nucleotide transhydrogenase 0.000
glucose-6-phosphate 1-dehydrogenase 0.000
OTUD6B 0.000
Transgelin-2 0.000
G6PDH 0.000
glutamine synthetase 0.000
alanine aminotransferase 0.000
phosphorylase, glycogen 0.000
phosphoenolpyruvate carboxykinase 0.000
NADP-ME 0.000
gCap39 0.000
ATP 0.000
glutamate pyruvate transaminase 0.000
uridine-cytidine kinase 2 0.000
NDUFA4L2 0.000
triosephosphate isomerase 0.000
MDH 0.000
pyruvate dehydrogenase complex 0.000
TEGT 0.000
ribosomal protein L36 0.000
PSA2 0.000
ropporin 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
aminoacylase 1 0.000
acid phosphatase 0.000
TPN 0.000
proteasome subunit alpha 0.000
NAD(+) kinase 0.000
enolase 0.000
adenylate kinase 0.000
Methylguanine-DNA methyltransferase 0.000
prohibitin 0.000
DECR1 0.000
lipoamide dehydrogenase 0.000
Glucose-6-phosphate dehydrogenase 0.000
secreted protein, acidic, cysteine-rich 0.000
BRAP2 0.000
succinyl coenzyme A synthetase 0.000
Malate dehydrogenase 0.000
glutamic dehydrogenase 0.000
nucleoside phosphorylase 0.000
IDP 0.000
Fms-related tyrosine kinase 3 0.000
PSA5 0.000
AVEN 0.000
PRKAG1 0.000
fatty acid synthase 0.000
phosphoglycerate mutase 0.000
glucose-6-phosphatase 0.000
PHI 0.000
Delta-aminolevulinic acid dehydratase 0.000
phosphoglucomutase 1 0.000
VDAC-2 0.000
more...
Disease
glioma 0.001
BDB 0.000
glioblastoma 0.000
adult brainstem glioma 0.000
Oligoastrocytoma 0.000
Oligoastrocytoma 0.000
ATRX 0.000
oligodendroglioma 0.000
acute myeloid leukemia 0.000
adult pilocytic astrocytoma 0.000
partial trisomy 2q 0.000
Oligodendroglioma 0.000
ovarian mixed germ cell tumor 0.000
Gliosarcoma 0.000
brain tumor 0.000
Tanycytic ependymoma 0.000
Anaplastic oligodendroglioma 0.000
Diffuse astrocytoma 0.000
astrocytoma 0.000
Periosteal chondroma 0.000
glioblastoma multiforme 0.000
anaplastic astrocytoma 0.000
Coxiella infection 0.000
Waldenstrom's disease 0.000
Glioblastoma 0.000
tumor 0.000
Maffucci's syndrome 0.000
Withdrawal bleeding 0.000
GSH 0.000
cancer 0.000
CPX 0.000
adult brain tumor 0.000
gliosarcoma 0.000
Herpetosoma 0.000
RAEB-2 0.000
chondrosarcoma 0.000
angioimmunoblastic T-cell lymphoma 0.000
mixed gliomas 0.000
giant cell glioblastoma 0.000
refractory cytopenia with multilineage dysplasia 0.000
enchondromatosis 0.000
Cholangiocarcinoma 0.000
syndrome X 0.000
FAB M1 0.000
tumorigenesis 0.000
Cholangiocarcinoma 0.000
enchondroma 0.000
AT/RT 0.000
Chondrosarcoma 0.000
Chondrosarcoma 0.000
AML progression 0.000
embryonal tumor 0.000
brain cancer 0.000
Hepatocarcinogenesis 0.000
adult AML 0.000
DIA 0.000
chondromatosis 0.000
leukemogenesis 0.000
Crabs 0.000
Sertoli-Leydig cell tumor 0.000
Sertoli-Leydig cell tumor 0.000
GS2 0.000
MPE 0.000
Middle cerebral artery occlusion 0.000
ICD 0.000
Endometrium 0.000
Endometrium 0.000
vitamin B6 deficiency 0.000
myelodysplastic syndrome 0.000
PCC 0.000
thalassemia 0.000
carcinogenesis 0.000
ependymoma 0.000
drug-induced hepatitis 0.000
HBD 0.000
RSI 0.000
hypoglycemic coma 0.000
GS1 0.000
KNO 0.000
biliary tract cancer 0.000
leukemia 0.000
hyperbilirubinemia 0.000
Chimera 0.000
tumor progression 0.000
SDS 0.000
chondrolysis 0.000
Copper deficiency 0.000
hematologic malignancies 0.000
pheochromocytoma 0.000
PGA 0.000
glutaric aciduria 0.000
PMS 0.000
cancer relapse 0.000
cold 0.000
PDC 0.000
caruncle 0.000
kwashiorkor 0.000
cerebral thrombosis 0.000
fatty liver 0.000
MRS 0.000
Reye's syndrome 0.000
Malignant transformation 0.000
FDH 0.000
craniopharyngioma 0.000
Rosenthal 0.000
propionic acidemia 0.000
Refsum disease 0.000
ASAT 0.000
MRD 0.000
mole 0.000
testicular seminoma 0.000
Condensation 0.000
LIP 0.000
mole 0.000
pediatric AML 0.000
refractory anemia 0.000
ATM 0.000
Diaphragm 0.000
mental retardation 0.000
mental retardation 0.000
Mendelian disorders 0.000
chondroblastoma 0.000
minimal residual disease 0.000
paraganglioma 0.000
Q fever 0.000
ADH 0.000
iron deficiency 0.000
MVA 0.000
G6PD deficiency 0.000
hyperphenylalaninemia 0.000
PTD 0.000
opisthorchiasis 0.000
tyrosinemia 0.000
alcoholic hepatitis 0.000
Farber 0.000
RAEB 0.000
gallbladder cancer 0.000
ganglioglioma 0.000
methylmalonic acidemia 0.000
L. infantum 0.000
PNET 0.000
viral pneumonia 0.000
tumor growth 0.000
erythroblastosis 0.000
tularemia 0.000
Leukemia 0.000
COL2A1 0.000
Hepatotoxicity 0.000
giardiasis 0.000
APL 0.000
aggressiveness 0.000
melanoma 0.000
PDR 0.000
chondroma 0.000
intracranial tumors 0.000
T-cell lymphoma 0.000
metabolic disorder 0.000
APL 0.000
anaplastic thyroid cancer 0.000
Neoplasms 0.000
more...
Symptom
Central post-stroke pain 0.000
Gasping 0.000
Spots 0.000
starvation 0.000
exhaustion 0.000
Decreased activity 0.000
Anoxia 0.000
neurological disability 0.000
eds 0.000
decreased appetite 0.000
nasal discharge 0.000
hypocapnia 0.000
oliguria 0.000
twitching 0.000
blurred vision 0.000
seizures 0.000
nausea 0.000
asthenia 0.000
flushing 0.000
weakness 0.000
nausea and vomiting 0.000
hypothermia 0.000
numbness 0.000
shortness of breath 0.000
hyperoxia 0.000
agitation 0.000
hunger 0.000
lethargy 0.000
hypotonia 0.000
functional recovery 0.000
headache 0.000
myalgia 0.000
acidity 0.000
dyspnea 0.000
collapse 0.000
arthralgia 0.000
hypercapnia 0.000
vomiting 0.000
dystonia 0.000
syncope 0.000
constipation 0.000
cough 0.000
thinning 0.000
fatigue 0.000
ataxia 0.000
anesthesia 0.000
tremor 0.000
diarrhea 0.000
pain 0.000
Drug
NADH 0.001
citric acid 0.000
Lysine hydrochloride 0.000
Carboxyatractyloside 0.000
Midostaurin 0.000
Fennel 0.000
lysine 0.000
ascorbate 0.000
Tween 40 0.000
1,8-Cineole 0.000
Rasburicase 0.000
Florfenicol 0.000
FAD 0.000
Lead acetate 0.000
Citric acid 0.000
C3H8 0.000
Kaolin 0.000
Clofibrate 0.000
Glycerol 0.000
Lactase 0.000
ID2 0.000
Depo-Provera 0.000
Palmitoyl 0.000
Premarin 0.000
Copaxone 0.000
Guanidine 0.000
anti-CD33 0.000
Guanidine 0.000
Artesunate 0.000
Gel 0.000
Adriamycin 0.000
SMP 0.000
ROS 0.000
CTT 0.000
Liraglutide 0.000
MEA 0.000
Maltose 0.000
Emodin 0.000
Fructose 0.000
CSI 0.000
Capsicum 0.000
Emodin 0.000
L-tyrosine 0.000
Kainic acid 0.000
Nitric Oxide 0.000
MgSO4 0.000
vitamin E 0.000
Acacia 0.000
Bevacizumab 0.000
Xanthium 0.000
Glutathione 0.000
Adenosine triphosphate 0.000
ADR 0.000
Frontal 0.000
Sodium nitroprusside 0.000
MDS 0.000
CTC 0.000
ETS 0.000
EE2 0.000
Arsenic trioxide 0.000
CTC 0.000
Honey 0.000
Kenyan 0.000
GEO 0.000
Coral 0.000
NH3 0.000
Parkin 0.000
Parkin 0.000
Asn 0.000
EPI 0.000
DHT 0.000
ABC 0.000
Angiotensin II 0.000
DHT 0.000
CDP 0.000
Leaf 0.000
Ethanol 0.000
MAP 0.000
pyridoxal phosphate 0.000
Alliance 0.000
ETA 0.000
Alanine 0.000
Growth hormone 0.000
Growth hormone 0.000
MRC 0.000
ROC 0.000
niacin 0.000
p75 0.000
lactose 0.000
G-CSF 0.000
ICI 0.000
Mutagen 0.000
Indomethacin 0.000
CaCl2 0.000
CaCl2 0.000
CaCl2 0.000
DNase I 0.000
CTX 0.000
TiO2 0.000
ZnO 0.000
Nephron 0.000
CSF 0.000
Cardiovasc 0.000
Dermatol 0.000
Enzyme
isocitrate dehydrogenase 0.999
isocitrate dehydrogenase 0.818
malate dehydrogenase 0.013
alpha-ketoglutarate dehydrogenase 0.006
aconitase 0.005
glucose-6-phosphate dehydrogenase 0.004
citrate synthase 0.004
fumarase 0.004
STK3 0.004
6-phosphogluconate dehydrogenase 0.004
6-phosphogluconate dehydrogenase 0.004
isocitrate lyase 0.003
succinate dehydrogenase 0.003
glutamate dehydrogenase 0.001
glutamate dehydrogenase 0.001
glutamate dehydrogenase 0.001
malate synthase 0.001
oxoglutarate dehydrogenase 0.001
lactate dehydrogenase 0.001
pyruvate dehydrogenase 0.001
EC 1.1.1.40 0.001
pyruvate dehydrogenase 0.001
pyruvate dehydrogenase 0.001
pyruvate kinase 0.001
phosphoglucomutase 0.001
pyruvate carboxylase 0.001
PEP phosphatase 0.001
phosphoglucose isomerase 0.000
homoisocitrate dehydrogenase 0.000
beta-hydroxybutyrate dehydrogenase 0.000
EC 1.1.1.98 0.000
trihydroxypterocarpan dimethylallyltransferase 0.000
phosphofructokinase 0.000
glycerol-3-phosphate dehydrogenase 0.000
hexokinase 0.000
gamma-lactonase 0.000
PH1722 0.000
tartrate dehydrogenase 0.000
glycerol-3-phosphate dehydrogenase 0.000
transhydrogenase 0.000
succinic dehydrogenase 0.000
phosphoenolpyruvate carboxykinase 0.000
phosphoenolpyruvate carboxykinase 0.000
phosphoenolpyruvate carboxykinase 0.000
aldolase 0.000
3-isopropylmalate dehydrogenase 0.000
glutathione reductase 0.000
succinyl-CoA synthetase 0.000
glutamate synthase 0.000
phosphoenolpyruvate carboxylase 0.000
aspartate aminotransferase 0.000
diaphorase 0.000
NADH dehydrogenase 0.000
glutamate synthase 0.000
formyltetrahydrofolate deformylase 0.000
gluconate dehydrogenase 0.000
glycerol 3-phosphate dehydrogenase 0.000
glutamate synthase 0.000
glycerophosphate phosphatase 0.000
EC 2.7.7.42 0.000
glutamic dehydrogenase 0.000
citrate lyase 0.000
malate oxidase 0.000
sorbitol dehydrogenase 0.000
SCS 0.000
EC 1.1.1.39 0.000
tripeptidase 0.000
acetate kinase 0.000
prolinase 0.000
phosphomannose isomerase 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
shikimate dehydrogenase 0.000
cytochrome oxidase 0.000
acetyl-CoA synthetase 0.000
glutamine synthetase 0.000
glyoxylate reductase 0.000
alanine aminotransferase 0.000
glyoxylate reductase 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
penicillopepsin 0.000
MDH 0.000
alcohol dehydrogenase 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
enolase 0.000
adenylate kinase 0.000
PdxA 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
diaphorase 0.000
acid phosphatase 0.000
MDH 0.000
complex I 0.000
phosphoenolpyruvate synthase 0.000
fumarate reductase 0.000
glucose-6-phosphatase 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
EC 1.1.1.82 0.000
citrate cleavage enzyme 0.000
sortase B 0.000
fructose 1,6-bisphosphatase 0.000
condensing enzyme 0.000
superoxide dismutase 0.000
glycolate oxidase 0.000
creatinine iminohydrolase 0.000
EC 1.1.1.38 0.000
glutathione peroxidase 0.000
3-oxoacid CoA-transferase 0.000
BCKDH 0.000
glycolate dehydrogenase 0.000
PDH 0.000
glycine dehydrogenase 0.000
glycine dehydrogenase 0.000
catalase 0.000
phytanoyl-CoA hydroxylase 0.000
alanine dehydrogenase 0.000
creatine kinase 0.000
2-oxoglutarate decarboxylase 0.000
phenylpyruvate decarboxylase 0.000
methylmalonate-semialdehyde dehydrogenase 0.000
nicotinic acid phosphoribosyltransferase 0.000
PGM 0.000
3-hydroxyacyl-CoA dehydrogenase 0.000
succinic semialdehyde dehydrogenase 0.000
ATP synthase 0.000
pyruvate decarboxylase 0.000
aryl-alcohol dehydrogenase 0.000
octopine dehydrogenase 0.000
alkaline phosphatase 0.000
2-hydroxyglutarate dehydrogenase 0.000
pyruvate:ferredoxin oxidoreductase 0.000
L-amino-acid oxidase 0.000
octanol dehydrogenase 0.000
N-acetylglucosamine kinase 0.000
3-hydroxyisobutyrate dehydrogenase 0.000
IMP cyclohydrolase 0.000
NADH kinase 0.000
3-hydroxyacyl-CoA dehydrogenase 0.000
glycine dehydrogenase 0.000
phosphoglycolate phosphatase 0.000
CPR 0.000
thiosulfate dehydrogenase 0.000
glycine decarboxylase 0.000
triose-phosphate isomerase 0.000
ribulose 5-phosphate 3-epimerase 0.000
phosphoglyceromutase 0.000
CMP-Neu5Ac hydroxylase 0.000
ATPase 0.000
phosphorylase 0.000
acetoacetyl-CoA thiolase 0.000
NADPH-diaphorase 0.000
3-hydroxybutyryl-CoA dehydrogenase 0.000
AICAR transformylase 0.000
creatininase 0.000
acetyl-CoA carboxylase 0.000
allantoicase 0.000
DNA methyltransferase 0.000
esterase D 0.000
acetoacetyl-CoA reductase 0.000
creatinase 0.000
CobB 0.000
6-phosphogluconate dehydratase 0.000
more...
Compound
isocitrate 0.038
NADP 0.015
hydroxyglutarate 0.009
2-oxoglutarate 0.005
NAD 0.003
NADPH 0.002
NAD 0.002
NADPH 0.002
2-Hydroxyglutarate 0.001
NADH 0.001
pentose 0.000
pentose 0.000
pentose 0.000
pentose 0.000
2-naphthyl laurate 0.000
Asparagusate 0.000
oxalacetate 0.000
nicotinamide 0.000
acetyl-CoA 0.000
TCA 0.000
6-phosphogluconate 0.000
glucose 0.000
glutamate 0.000
C6H6O7 0.000
phosphate 0.000
Sinulariolide 0.000
DPN 0.000
ADP 0.000
ADP 0.000
A 153 0.000
K-38 0.000
Butylmalonate 0.000
2-Oxoglutarate 0.000
ADP 0.000
C4H6O6 0.000
L-Lysine monohydrochloride 0.000
glucose-6-phosphate 0.000
ATP 0.000
alcohol dehydrogenase 0.000
1-butanesulfonic acid 0.000
acetate 0.000
CIT 0.000
Palmitoyl-L-carnitine 0.000
PDAP 0.000
DEPA 0.000
Meldola's Blue 0.000
succinic acid 0.000
2-oxoadipate 0.000
glutamine 0.000
IDP 0.000
Canaline 0.000
2-keto-4-hydroxyglutarate 0.000
DEPA 0.000
Malate 0.000
Meldola's Blue 0.000
oxygen 0.000
Glyoxylate 0.000
Sakuranetin 0.000
hexose 0.000
hexose 0.000
hexose 0.000
CoA 0.000
p-Nitroanisole 0.000
C6H8O7 0.000
KI3 0.000
glycerol 0.000
TET 0.000
TET 0.000
GSH 0.000
GSH 0.000
hexose 0.000
PDH 0.000
malic acid 0.000
Phenylpyruvate 0.000
4-oxobutanoic acid 0.000
AMP 0.000
dihydroxyacetone-phosphate 0.000
manganese 0.000
DNA 0.000
Coumaphos 0.000
Pyruvate kinase 0.000
OH-M 0.000
Xanthurenic acid 0.000
Mg2+ 0.000
nitrogen 0.000
itaconic acid 0.000
alpha-isopropylmalate 0.000
Glycolate 0.000
Glutamate 0.000
sedoheptulose 7-phosphate 0.000
Methionine sulfoximine 0.000
alanine 0.000
1-naphthyl acetate 0.000
Malonate 0.000
Trenimon 0.000
Metaproterenol 0.000
Dydrogesterone 0.000
Potassium dichromate 0.000
Phytanic acid 0.000
D-Glyceraldehyde 0.000
Piperine 0.000
Phenylglyoxal 0.000
Flux 0.000
lysine 0.000
Azoxymethane 0.000
Bromophenol Blue 0.000
Azaserine 0.000
ammonium 0.000
Glucose 6-phosphate 0.000
MTU 0.000
Potassium chloride 0.000
CO2 0.000
Sodium deoxycholate 0.000
erythrose-4-phosphate 0.000
ornithine 0.000
ornithine 0.000
ornithine 0.000
ornithine 0.000
ornithine 0.000
Ethionine 0.000
succinic acid 0.000
succinic acid 0.000
succinic acid 0.000
succinic acid 0.000
2-keto-3-deoxygluconate 0.000
PEP 0.000
Lactate 0.000
2,4-pentanedione 0.000
2,4-pentanedione 0.000
2,4-pentanedione 0.000
Mancozeb 0.000
Phosphoserine 0.000
2,4-pentanedione 0.000
2,4-pentanedione 0.000
2,4-pentanedione 0.000
1,2-cyclohexanediamine 0.000
1,2-cyclohexanediamine 0.000
2,4-pentanedione 0.000
2,4-pentanedione 0.000
2,4-pentanedione 0.000
2,4-pentanedione 0.000
2,4-pentanedione 0.000
2,4-pentanedione 0.000
2,4-pentanedione 0.000
2,4-pentanedione 0.000
S-allylcysteine 0.000
Catalpol 0.000
Coenzyme A 0.000
GSSG 0.000
DETA 0.000
1H-indene 0.000
pyridine 0.000
PIPES 0.000
PIPES 0.000
PIPES 0.000
arginine 0.000
adenylate 0.000
glutamic acid 0.000
6-aminonicotinamide 0.000
FAD 0.000
more...