Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.1.1.37 (malate dehydrogenase)
 4,591 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
malate dehydrogenase 3656
MDH 793
lactate dehydrogenase 720
NADP 520
NADH 493
NAD 411
isocitrate dehydrogenase 402
citrate synthase 351
ATP 322
Sep 309
glucose-6-phosphate dehydrogenase 302
LDH 249
aspartate aminotransferase 247
Mol 235
glutamate dehydrogenase 217
hexokinase 216
pyruvate kinase 216
NADPH 196
esterase 167
mitochondrial malate dehydrogenase 160
catalase 148
phosphoenolpyruvate carboxylase 148
fumarase 146
6-phosphogluconate dehydrogenase 141
superoxide dismutase 138
ATPase 138
acid phosphatase 130
alkaline phosphatase 122
phosphofructokinase 120
NAD+ 119
alcohol dehydrogenase 111
thioredoxin 105
CO2 104
phosphoenolpyruvate carboxykinase 104
aconitase 99
ADP 99
insulin 98
PGM 96
glyceraldehyde-3-phosphate dehydrogenase 93
creatine kinase 93
alpha-ketoglutarate dehydrogenase 92
Malate dehydrogenase 86
SDH 85
TCA 84
SOD 79
oxidoreductase 77
pyruvate dehydrogenase 77
fructose-1,6-bisphosphatase 75
pyruvate carboxylase 73
decarboxylating 72
GPI 71
alanine aminotransferase 71
adenylate kinase 70
NADP+ 70
dimeric 69
reductase 67
cytochrome 66
peroxidase 63
NADH dehydrogenase 62
phosphoglucose isomerase 60
polypeptide 59
IDH 58
ferredoxin 58
cytosolic malate dehydrogenase 56
ATP synthase 55
cytochrome c 54
PHI 52
AMP 52
SDS 50
glutathione reductase 50
chaperonin 49
cytochrome c oxidase 48
TOF 47
enolase 46
PDH 45
glutamine synthetase 45
Gen 45
glycerol-3-phosphate dehydrogenase 42
albumin 42
GSH 42
ADH 40
Pseudomonas 40
endoplasmic reticulum 39
beta-glucuronidase 39
GDH 38
glucose-6-phosphatase 38
NADP-malic enzyme 37
GroES 36
G6PDH 35
glutathione peroxidase 35
G6PD 34
microsomal 34
MDH1 34
LAP 34
phosphatase 33
MDH2 33
glycogen phosphorylase 33
fumarate hydratase 32
amylase 31
triosephosphate isomerase 30
PGI 30
GAPDH 29
carbonic anhydrase 29
sorbitol dehydrogenase 29
phosphoglycerate kinase 29
isocitric dehydrogenase 29
EST 29
membrane-bound 29
NMR 27
ACL 27
NADP-dependent isocitrate dehydrogenase 27
leucine aminopeptidase 27
PEP 26
6PGD 26
serum albumin 26
L-lactate dehydrogenase 26
thioredoxin reductase 26
diaphorase 25
Bot 25
ACP 24
peptidase 24
MPI 24
epididymal 24
AAT 24
PGD 24
fructose 1,6-bisphosphatase 23
EST) 23
5'-nucleotidase 23
CAT 22
NADP-dependent malic enzyme 22
Chlamydomonas 22
2-oxoglutarate dehydrogenase 22
Hexokinase 22
adenosine triphosphatase 22
Citrate synthase 22
FAD 21
lipoprotein lipase 21
crystallin 20
hydroxypyruvate reductase 20
pyruvate dehydrogenase complex 19
acetylcholinesterase 19
Malic enzyme 19
hemoglobin 19
fatty acid synthase 19
HSP70 19
3-hydroxyacyl-CoA dehydrogenase 18
AST 18
Thioredoxin 18
CPK 18
lysozyme 18
glycolytic enzyme 18
collagen 17
PGDH 17
Nei 17
acetyl-CoA carboxylase 17
glucokinase 17
Glucose-6-phosphate dehydrogenase 16
spermatozoa 16
myosin 16
GPT 16
more...
Disease
cancer 59
tumor 52
SDS 50
cold 47
GSH 42
ADH 40
diabetes 40
LAP 34
leishmaniasis 32
worms 28
ischemia 27
ACP 24
Mycobacterium 21
depression 20
carcinogenesis 17
dehydration 15
hepatocellular carcinoma 15
ASAT 15
DIA 14
ALD 14
Alzheimer's disease 14
obesity 14
West 12
tuberculosis 12
FDH 11
mole 11
carcinoma 11
myocardial infarction 11
mole 11
Schistosoma mansoni 11
chlorosis 11
Mycoplasma 10
infectious diseases 10
Brucella abortus 10
Chagas 10
acute pancreatitis 9
atherosclerosis 9
L. infantum 9
Infection 9
dilated cardiomyopathy 9
Haemophilus 9
hyperglycemia 9
brucellosis 9
heart failure 9
fatty liver 8
leukemia 8
Echinococcus 8
ICD 8
hypertension 8
lung cancer 8
Klebsiella 8
Benson 8
epididymis 8
schizophrenia 7
fungal infection 7
malaria 7
adenocarcinoma 7
pancreatitis 7
coma 7
pyelonephritis 7
uterus 7
pheochromocytoma 7
middle ear 6
hypothyroidism 6
abortion 6
Parkinson's disease 6
PCC 6
dyslipidemia 6
CAM 6
amyotrophic lateral sclerosis 5
cholera 5
dementia 5
Wright 5
PER 5
hepatitis 5
hypoglycemia 5
premenstrual syndrome 5
virus infection 5
Dissociation 5
glioma 5
MCF 5
cataract 5
PMS 5
tumor growth 5
sarcoma 5
coronary artery disease 5
bipolar disorder 5
cardiomyopathy 4
HSP 4
Evans 4
mania 4
heart disease 4
type 2 diabetes 4
epilepsy 4
metabolic disorder 4
hyperthyroidism 4
stroke 4
Schistosoma japonicum 4
Klebs 4
Poland 4
alcoholic cardiomyopathy 4
PGA 4
pancreatic cancer 4
SEM 4
Sweet 4
cerebral ischemia 4
MNS 4
trisomy 3
myocarditis 3
FAS 3
tyrosinemia 3
enteropathy 3
CCD 3
infertility 3
Rous sarcoma 3
tumorigenesis 3
muscular atrophy 3
Brill 3
astrocytoma 3
malnutrition 3
volvulus 3
onchocerciasis 3
G6PD deficiency 3
acute myeloid leukemia 3
schistosomiasis 3
tic 3
anemia 3
paracoccidioidomycosis 3
Huntington's disease 3
paraganglioma 3
acute renal failure 3
American cutaneous leishmaniasis 3
Brown 3
melanoma 3
wasting 3
cognitive impairment 3
myocardial ischemia 3
cornea 3
pneumonia 3
testicular atrophy 3
fits 3
glioblastoma 3
toxoplasmosis 3
Brucella melitensis 3
lichen 3
seminal vesicles 3
iron deficiency 3
hyperinsulinemia 3
renal failure 3
acute myocardial infarction 3
liver disease 3
otitis media 2
Hyperamylasemia 2
African trypanosomiasis 2
Wells 2
mental retardation 2
kala-azar 2
EDC 2
Thymus 2
hepatic encephalopathy 2
more...
Symptom
starvation 30
acidity 16
fatigue 12
collapse 12
exhaustion 9
seizures 8
pain 6
anesthesia 6
Decreased activity 3
stigma 3
twitching 2
agitation 2
splenomegaly 2
eds 2
discomfort 2
discomfort 2
anorexia 2
hypothermia 2
syncope 1
nausea 1
ACHE 1
tinnitus 1
hypotonia 1
dizziness 1
tremor 1
lethargy 1
Tenderness 1
spasm 1
flushing 1
hyperoxia 1
DNA marker 1
vertigo 1
weakness 1
angina 1
Deafferentation 1
pallor 1
hunger 1
CSR 1
hepatomegaly 1
vomiting 1
ataxia 1
chest pain 1
functional recovery 1
diarrhea 1
dystonia 1
Drug
NADH 499
citric acid 96
lysine 42
ascorbate 34
FAD 21
Leaf 16
Gel 16
vitamin E 15
ROS 10
Asn 10
lactose 9
Alanine 7
Ethanol 7
CAM 6
Capsicum 5
ABC 5
Fructose 5
caffeine 5
pyridoxal phosphate 5
Cibacron Blue 4
NH3 4
Nephron 4
Cardiovasc 4
Adriamycin 4
ACT 4
OTC 3
L-tyrosine 3
OTC 3
CaCl2 3
Kenyan 3
ZnO 3
CaCl2 3
CaCl2 3
Glucagon 3
DHT 2
Maltose 2
ampicillin 2
Indomethacin 2
MAP 2
NBT 2
Triclosan 2
Fennel 2
THF 2
CSF 2
Naftidrofuryl 2
PTC 2
EE2 2
Clofibrate 2
Arava 2
TAC 2
ICI 2
Adenosine triphosphate 2
Diurnal 2
Glutathione 2
IL-2 2
DHT 2
Piracetam 1
Sodium valproate 1
Emodin 1
CSI 1
HCH 1
Pentostam 1
Photofrin II 1
HCG 1
VCR 1
Emodin 1
CoCl2 1
Adenosine deaminase 1
Mazindol 1
TMX 1
1,8-Cineole 1
MRC 1
TiO2 1
CTX 1
Guanidine 1
CTC 1
Scopolamine 1
CER 1
Parkin 1
Galactose 1
Sodium nitroprusside 1
Fluorescein 1
IPM 1
Cytidine 1
ETA 1
Hypaque 1
Photofrin 1
ENT 1
Guar gum 1
Monit 1
Malonaldehyde 1
CDP 1
C4H10 1
Carotenoid 1
FLP 1
RBT 1
EPI 1
Parkin 1
Propentofylline 1
IFN-gamma 1
AKM 1
Vitamin A 1
Atabrine 1
Guanidine 1
Vitamin K 1
Spectrum 1
Ketoconazole 1
Ergosterol 1
DMI 1
Bifidobacterium 1
Pepstatin 1
CTC 1
ROC 1
Ouabain 1
Soybean oil 1
Vitamin E 1
Isoniazid 1
RFP 1
ADR 1
Sulfopyruvate 1
Flunitrazepam 1
Fluorescein 1
PTH 1
Hypaque 1
Cremophor EL 1
Sterile water 1
Activase 1
Parbendazole 1
PE2 1
PFT 1
EPA 1
Mutagen 1
Citric acid 1
CoCl2 1
Rasburicase 1
Glycerol 1
Cellulase 1
Diphenhydramine 1
3-Methyladenine 1
Cellulose acetate 1
Coral 1
Estrogens 1
Lipidex 1
NAG 1
Human Serum Albumin 1
Enzyme
malate dehydrogenase 4591
lactate dehydrogenase 804
MDH 791
MDH 791
isocitrate dehydrogenase 432
isocitrate dehydrogenase 425
glucose-6-phosphate dehydrogenase 396
succinate dehydrogenase 392
citrate synthase 369
aspartate aminotransferase 294
phosphoenolpyruvate carboxykinase 244
phosphoenolpyruvate carboxykinase 242
phosphoenolpyruvate carboxykinase 234
glutamate dehydrogenase 221
glutamate dehydrogenase 221
glutamate dehydrogenase 218
hexokinase 217
pyruvate kinase 216
superoxide dismutase 203
fumarase 177
phosphoenolpyruvate carboxylase 168
catalase 166
ATPase 161
diaphorase 154
alcohol dehydrogenase 151
6-phosphogluconate dehydrogenase 143
6-phosphogluconate dehydrogenase 143
phosphofructokinase 139
alpha-ketoglutarate dehydrogenase 134
glyceraldehyde-3-phosphate dehydrogenase 133
acid phosphatase 130
glyceraldehyde-3-phosphate dehydrogenase 125
alanine aminotransferase 125
phosphoglucose isomerase 124
alkaline phosphatase 123
glyceraldehyde-3-phosphate dehydrogenase 119
phosphoglucomutase 116
aconitase 115
cytochrome oxidase 114
pyruvate dehydrogenase 112
creatine kinase 111
PGM 110
aldolase 105
glyceraldehyde-3-phosphate dehydrogenase 103
glycerol-3-phosphate dehydrogenase 99
succinic dehydrogenase 99
glyceraldehyde-3-phosphate dehydrogenase 93
glycerol-3-phosphate dehydrogenase 92
complex I 89
adenylate kinase 85
pyruvate dehydrogenase 79
pyruvate dehydrogenase 77
isocitrate lyase 75
pyruvate carboxylase 75
phosphorylase 67
peroxidase 67
CPR 66
NADH dehydrogenase 64
ATP synthase 61
EC 1.1.1.40 59
fructose 1,6-bisphosphatase 55
glutathione reductase 51
chaperonin 49
enolase 49
glutamine synthetase 46
PDH 44
ACE 44
ADH 41
fumarate reductase 40
phosphoglycerate kinase 40
malate synthase 39
beta-glucuronidase 39
glucose-6-phosphatase 38
diaphorase 36
glutathione peroxidase 36
acetylcholinesterase 33
EC 1.1.1.82 33
NAD+ oxidoreductase 33
trypsin 33
thioredoxin reductase 32
monoamine oxidase 31
gamma-glutamyl transpeptidase 31
lactic acid dehydrogenase 31
NADPH-diaphorase 31
sorbitol dehydrogenase 30
NQO1 30
carbonic anhydrase 30
aldehyde dehydrogenase 30
beta-hydroxybutyrate dehydrogenase 30
glutathione S-transferase 29
SCS 29
leucine aminopeptidase 29
3-hydroxyacyl-CoA dehydrogenase 28
rubisco 27
3-hydroxyacyl-CoA dehydrogenase 27
PPDK 26
5'-nucleotidase 25
succinyl-CoA synthetase 25
cholinesterase 23
hydroxypyruvate reductase 22
invertase 22
citrate lyase 22
phosphoribulokinase 22
peroxiredoxin 22
lipase 21
lipoprotein lipase 21
ACS 20
phosphomannose isomerase 20
alpha-glucosidase 20
glucokinase 20
hydroxypyruvate reductase 19
lysozyme 19
ornithine transcarbamylase 19
nitrate reductase 18
glutamic dehydrogenase 18
AST 18
nitrate reductase 18
pyruvate decarboxylase 18
15-hydroxyprostaglandin dehydrogenase 17
nitrate reductase 17
nitrate reductase 17
nitrate reductase 17
protein kinase 17
nitrate reductase 17
acetyl-CoA carboxylase 17
beta-galactosidase 16
RNase 16
acetate kinase 16
aldehyde dehydrogenase 16
fructokinase 15
luciferase 15
carboxylesterase 14
formate dehydrogenase 14
proteasome 14
RNase 14
glutamate synthase 14
formate dehydrogenase 14
PTA 14
formate dehydrogenase 14
aldehyde dehydrogenase 13
aldehyde dehydrogenase 13
EC 1.1.1.39 13
glycolate oxidase 13
pyruvate:ferredoxin oxidoreductase 13
shikimate dehydrogenase 13
oxaloacetate decarboxylase 13
aldehyde dehydrogenase 13
transhydrogenase 12
oxoglutarate dehydrogenase 12
rhodanese 12
ascorbate peroxidase 12
adenosine deaminase 12
tyrosine aminotransferase 11
EC 1.1.1.38 11
arginase 11
glutamate synthase 11
KAT 11
glutamate synthase 11
acetyl-CoA synthetase 11
adenosine deaminase 11
more...
Compound
NADP 602
NAD 524
glucose 520
NADH 497
NAD 411
Dec 365
phosphate 342
ATP 322
oxygen 248
glutamate 208
DNA 206
NADPH 197
NADPH 196
water 188
acetate 162
2-oxoglutarate 154
alcohol dehydrogenase 145
CO2 129
nicotinamide 127
sodium 115
alanine 114
oxalacetate 105
nitrogen 104
ADP 104
CoA 103
salt 101
malic acid 101
ADP 101
ADP 99
hydrogen 95
pentose 89
pentose 89
pentose 89
pentose 89
TCA 86
ammonium 77
ethanol 74
glycerol 74
Clin 73
urea 71
cysteine 70
calcium 69
isocitrate 67
sulfate 64
arginine 63
SDS 63
Malate 59
AMP 55
malic acid 53
lysine 51
acetyl-CoA 49
TOF 47
malic acid 47
malic acid 47
His 46
pyridine 46
galactose 46
glutamine 46
leucine 44
PDH 44
Lactate 43
serine 43
GSH 42
GSH 42
succinic acid 41
Asp 40
glucose-6-phosphate 40
ammonia 39
nitrate 37
zinc 37
Mg2+ 36
iron 36
DEAE 32
proline 32
Triton X-100 31
PEG 29
PEP 29
tyrosine 29
manganese 28
hexose 28
hexose 27
Gly 27
hexose 27
hexose 27
NH2 27
copper 25
Pac 25
potassium 25
cadmium 24
methanol 24
methionine 24
AAT 23
cyanide 23
tryptophan 23
tryptophan 23
EDTA 23
tryptophan 23
tryptophan 23
EDTA 23
Glutamate 23
Tris 22
CAT 22
CAT 22
CAT 22
acetic acid 22
Pyruvate 21
Sucrose 21
aspartic acid 21
threonine 21
FAD 21
adenylate 20
carbonate 19
CIT 19
H2O2 19
Tris 19
acrylamide 19
succinic acid 18
succinic acid 18
phosphorus 18
succinic acid 18
guanidine 18
creatinine 18
dicarboxylic acid 18
Thioredoxin 18
aluminum 18
succinic acid 18
cAMP 17
Ile 17
HCl 17
oxalate 17
Insulin 16
GTP 16
GPT 16
MgCl2 16
phenazine 15
Phe 15
silver 14
aldehyde 14
ALP 14
ubiquinone 14
PEG 13
MAK 13
MDA 12
6-phosphogluconate 12
retinol 12
uridine 12
CAM 12
valine 12
alloxan 12
asparagine 11
hydroxyglutarate 11
bromide 11
GABA 11
nickel 11
GABA 11
Cardiol 11
2-mercaptoethanol 11
xylose 11
isoleucine 10
Fumarate 10
more...