Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.1.1.3 (HSD)
 3,464 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
HSD11B1L protein 13.2
SDR9C4 13.2
HSD 13.1
phosphoinositide-3-kinase, catalytic, beta polypeptide 12.2
HSD11B1L 12.2
HSD8 12.0
HSD-1 11.8
17-beta-HSD 11.8
17 beta-hydroxysteroid dehydrogenase 11.7
PHA I 11.6
FAM89A 11.6
chlordecone reductase 11.4
HSD3 11.4
20 alpha-hydroxysteroid dehydrogenase 11.4
17beta-hydroxysteroid dehydrogenase type 3 11.4
HSD13 11.2
HSD5 11.0
HSD1 10.9
RB3 protein 10.8
3 beta-HSD type II 10.8
hydroxysteroid dehydrogenase-like protein 10.8
CKLFSF2 10.8
StAR 10.8
3alpha-HSD 10.7
3 beta-HSD 10.6
3-beta-hydroxysteroid dehydrogenase 10.6
RODH 10.6
3 beta-hydroxysteroid dehydrogenase 10.5
HSD4 10.5
MT1R 10.5
P450C17 10.4
HSD2 10.4
RDHL 10.4
P450scc 10.3
alpha-kinase 1 10.2
Retinol dehydrogenase 10.2
HSD17B6 10.2
dihydrodipicolinate synthase 10.1
P450c17 10.1
20alpha-hydroxysteroid dehydrogenase 10.0
neuregulin 4 10.0
HSD11 10.0
CYP11A 10.0
steroid acute regulatory protein 10.0
HSD17B3 9.9
17beta-hydroxysteroid dehydrogenase 9.9
P450c21 9.9
17-beta-hydroxysteroid dehydrogenase 9.7
HSD-3.8 9.7
steroidogenic acute regulatory protein 9.7
CYP11A1 9.7
17beta hydroxysteroid dehydrogenase 9.6
ADP-ribosylation factor 3 9.6
PDIA2 9.6
SCHAD 9.6
20-alpha-hydroxysteroid dehydrogenase 9.6
HSD3B2 9.5
FRA2 9.5
Smad9 9.5
CDC47 9.5
HSD3B7 9.5
Pur beta 9.4
AKR1C2 9.3
short chain dehydrogenase/reductase 9.3
PRRP 9.3
short-chain alcohol dehydrogenase 9.2
HDH 9.2
carbonyl reductase 9.1
CYP17A1 9.1
opioid receptor mu 9.1
APPH 9.1
SC5D 9.1
AKR1C1 9.0
saccharopine dehydrogenase 9.0
CREBZF 9.0
GHV 9.0
UNC45 9.0
DDX 9.0
Zhangfei 8.9
KSR 8.9
more...
Disease
Benign meningioma 12.6
Sex cord-stromal tumor 11.6
PHA I 11.6
Alcohol-induced pseudo-Cushing's syndrome 11.6
Late onset congenital adrenal hyperplasia 10.6
Chronic inflammatory disease 9.8
Male pseudohermaphroditism 9.8
WNS 9.2
PHA2 9.2
PHA1 9.2
3 beta-HSD deficiency 9.1
MGA3 9.0
Androgen excess 8.4
ADSA 8.4
adrenal hypertension 8.3
testicular dysfunction 8.3
NSD 7.8
Leydig cell hyperplasia 7.6
mumps orchitis 7.6
Testes 7.5
Leydig cell hypoplasia 7.4
Gordon's syndrome 7.4
cystic ovary 7.4
Allergic fungal sinusitis 7.3
Hypoxic-ischemic brain injury 7.2
adrenal neoplasm 7.2
IPS 7.2
Liddle's syndrome 7.1
hypokalemic alkalosis 6.8
Male hypogonadism 6.7
11 beta-hydroxylase deficiency 6.6
Pseudopregnancy 6.6
congenital adrenal hyperplasia 6.5
Testis 6.5
Testis 6.5
Steroids 6.4
Ondine's curse 6.4
Ondine's curse 6.4
BCD 6.4
ovarian dysfunction 6.4
Endometrium 6.3
Endometrium 6.3
hyporeninemic hypoaldosteronism 6.2
21-hydroxylase deficiency 6.1
hypercortisolism 6.0
MSD 6.0
adrenal hyperplasia 5.9
disruptive behavior disorder 5.8
ISD 5.8
DHD 5.8
XY females 5.7
DHD 5.7
FSI 5.7
external genitalia 5.7
FHM 5.7
Testicular torsion 5.6
hypoactive sexual desire disorder 5.6
PMS 5.5
Cushing's syndrome 5.5
CIE 5.4
endocrine disorder 5.4
moderate obesity 5.4
MSF 5.4
aldosteronism 5.4
Leydig cell tumor 5.4
FPP 5.3
Hallervorden-Spatz disease 5.2
hypochloremia 5.2
anovulation 5.2
Angle Class I 5.2
polycystic ovary syndrome 5.1
Sertoli cell tumor 5.1
HBD 5.1
epididymis 5.1
hypoaldosteronism 5.1
MIN 5.1
MIN 5.1
TBS 5.1
PND 5.0
emotional disorder 5.0
more...
Symptom
Balding 8.1
Tissue sensitivity 8.0
masculinization 6.5
Cushingoid 6.4
Cushingoid 6.4
voice change 5.9
male subfertility 5.1
Decreased activity 5.1
loss of balance 4.3
CSR 3.7
dry skin 3.2
hypersomnia 3.1
polydipsia 3.1
muscle stiffness 2.9
polyuria 2.6
physical appearance 2.6
sciatica 2.6
rhinorrhea 2.0
acute stress 2.0
pallor 1.9
knee pain 1.7
snoring 1.7
HSA 1.6
flushing 1.5
dysarthria 1.3
acidity 1.3
agitation 1.2
dystonia 1.1
hepatosplenomegaly 1.1
fatigue 1.0
ENT 0.8
hunger 0.7
lethargy 0.7
hypothermia 0.7
hepatomegaly 0.7
hypotonia 0.6
starvation 0.6
overweight 0.5
exhaustion 0.4
distraction -0.0
respiratory distress -0.1
splenomegaly -0.1
low back pain -0.1
insomnia -0.2
anesthesia -0.3
thinning -0.3
back pain -0.4
discomfort -0.4
functional recovery -0.5
tremor -1.0
headache -1.0
discomfort -1.3
pain -1.4
seizures -1.5
dyspnea -1.6
analgesia -1.6
diarrhea -1.6
abdominal pain -1.8
vomiting -1.8
weakness -2.0
Drug
Aicar 12.2
Saccharin sodium 11.2
Trilostane 10.4
Gadofosveset trisodium 10.2
Factrel 9.7
Bear bile 9.7
Adosterol 9.6
Carbenoxolone 9.5
Almora 9.0
Ganaxolone 8.8
Phosphagen 8.2
Gestrinone 8.2
Vitamin-E 7.9
CEG 7.7
Pregnenolone 7.6
Benzofuran 7.6
CEG 7.5
Lead acetate 7.4
Alarin 7.3
Cortrosyn 7.2
Fosmidomycin 7.1
Dihydrotestosterone 7.1
DHT 7.0
Calcium silicate 7.0
Cortrosyn 7.0
DHT 6.9
Ciprofibrate 6.9
Ethibond 6.5
Ketorolac tromethamine 6.4
Dutasteride 6.3
Digitalis 6.2
Tenoxicam 6.2
FSH-beta 6.2
FSH-beta 6.1
Furan 6.1
Arimidex 6.0
Sulphasalazine 5.9
FSH-beta 5.9
SrCl2 5.8
SrCl2 5.6
Camphor 5.6
Tween 40 5.6
Camphor 5.5
Glycyrrhiza 5.5
Aztec 5.4
Parlodel 5.4
Estriol 5.4
DEX 5.3
Peridex 5.3
HCG 5.2
Primaquine 5.2
Estrogens 5.2
Clodronate 5.2
EMB 5.1
Zmax 5.1
Rosiglitazone 5.1
KCL 5.1
Silica gel 5.0
Ketorolac 5.0
EE2 4.9
NADH 4.9
R1881 4.9
Clomiphene citrate 4.9
Rimonabant 4.8
MAP 4.8
RSM 4.7
Ketoconazole 4.7
ATV 4.6
Modafinil 4.6
Xanthium 4.5
Activin 4.4
Forskolin 4.4
Cibacron Blue 4.3
THF 4.3
Leucovorin 4.2
Luteinizing 4.1
Triclosan 4.1
Troglitazone 4.1
Ringer's solution 4.0
lysine 3.7
more...
Enzyme
HSD 13.2
EC 1.1.1.201 13.2
3-KSR 12.6
3alpha(17beta)-HSD 12.2
12alpha-hydroxysteroid dehydrogenase 11.8
aspartokinase 11.6
3beta-HSDH 11.4
homoserine kinase 11.3
11beta-hydroxysteroid dehydrogenase 11.3
17beta-HSD 11.3
3beta-hydroxysteroid dehydrogenase 11.3
threonine synthase 11.2
7alpha-hydroxysteroid dehydrogenase 11.1
17beta-HSD 10.9
20alpha-hydroxysteroid dehydrogenase 10.6
dihydrodipicolinate synthase 10.3
prostaglandin F synthase 10.1
hydroxyprostaglandin dehydrogenase 10.0
cytochrome P-450scc 9.8
diaminopimelate dehydrogenase 9.7
aspartate semialdehyde dehydrogenase 9.7
3alpha-hydroxysteroid dehydrogenase 9.3
17-ketoreductase 9.2
dihydrodipicolinate reductase 9.2
homoserine transacetylase 9.1
carbonyl reductase 9.0
5beta-reductase 9.0
saccharopine dehydrogenase 8.9
tropinone reductase 8.8
EC 5.3.3.2 8.8
threonine deaminase 8.7
ecdysone 20-monooxygenase 8.7
dihydrodiol dehydrogenase 8.7
NAD+ synthetase 8.6
3-hydroxyisobutyryl-CoA hydrolase 8.6
25-hydroxyvitamin D3 1alpha-hydroxylase 8.5
20beta-hydroxysteroid dehydrogenase 8.5
steroid sulfotransferase 8.1
diaminopimelate decarboxylase 8.0
SsuD 8.0
SMT1 7.8
SAICAR synthetase 7.6
PGE2-9-ketoreductase 7.5
5alpha-reductase 7.5
5alpha-reductase 7.5
GPH 7.4
estrogen sulfotransferase 7.2
15-hydroxyprostaglandin dehydrogenase 7.2
GSase 7.2
threonine dehydrogenase 7.1
phosphoserine phosphatase 7.1
homocitrate synthase 7.0
exonuclease VII 7.0
cycloartenol synthase 6.8
lanosterol 14alpha-demethylase 6.8
steroid isomerase 6.8
21-hydroxylase 6.7
estrogen sulfotransferase 6.6
phosphomevalonate kinase 6.6
PDH 6.3
sterol carrier protein 6.3
CYP7B1 6.2
aldehyde reductase 6.2
nicotinamide mononucleotide adenylyltransferase 6.2
aldehyde reductase 6.2
aldehyde reductase 6.1
7-dehydrocholesterol reductase 6.0
prephenate dehydratase 5.9
ferredoxin reductase 5.8
sulfite reductase 5.8
sulfite reductase 5.8
3-isopropylmalate dehydrogenase 5.8
sulfite reductase 5.8
ATP sulfurylase 5.7
cystathionine gamma-synthase 5.7
triose-phosphate isomerase 5.6
Lod 5.6
sulfatase 5.5
lysine decarboxylase 5.5
aspartase 5.4
more...
Compound
3-(4-methoxyphenyl)-2-thioxo-1,3-thiazolidin-4-one 13.2
1-(4-methoxyphenyl)-2-methyl-1-propanone 12.2
alpha-THF 11.5
undecanamide 10.9
7alpha-Methyl-19-nortestosterone 10.8
Lactucin 10.6
7-Ketolithocholic acid 10.4
alpha-cortol 10.4
6-Hydroxyflavone 10.4
pregn-5-ene-3,20-dione 10.2
Pyridoxal hydrochloride 10.2
11-Dehydrocorticosterone 10.2
Remin 10.2
GDMA 10.0
2-methylcyclopentanone 9.6
Pyridoxine hydrochloride 9.5
C3H7NO2 9.4
Miroestrol 9.3
7H-benzo[c]fluorene 9.0
HPTE 8.8
22R-hydroxycholesterol 8.7
Glycyrrhetinic acid 8.7
androstan-17-one 8.7
Promegestone 8.7
androstan-17-one 8.7
dimethyl isophthalate 8.7
diphenyl phthalate 8.7
diphenyl phthalate 8.6
androstane-3,17-dione 8.6
Glycyrrhetinic acid 8.6
Dicyclohexyl 8.6
Androstenedione 8.4
4-tert-Octylphenol 8.3
17alpha-hydroxypregnenolone 8.3
Quinalphos 8.2
4-tert-Octylphenol 8.2
Hydroxyflutamide 8.2
2-propyn-1-ol 8.1
Coumestrol 8.1
androstan-3-one 8.1
2-methylcyclohexanone 8.1
2-methylcyclohexanone 8.1
L-threonine 8.0
Abietic acid 8.0
2-hydrazinopyridine 8.0
Cosyntropin 8.0
androstane 8.0
Norethisterone acetate 8.0
2-methylcyclohexanone 7.9
Trey 7.9
Tributyltin chloride 7.9
homoserine 7.8
Citronellol 7.8
Allethrin 7.6
homoserine 7.6
homoserine 7.6
Copper chloride 7.6
Pregnenolone 7.6
Glycyrrhizin 7.6
cholestan-3-one 7.6
Methoxychlor 7.5
dimethyl oxalate 7.5
cholestan-3-one 7.5
dicyclohexyl phthalate 7.5
Ethylparaben 7.5
Allopregnanolone 7.5
Daidzin 7.4
Cortisone acetate 7.3
Allopregnanolone 7.3
Echinomycin 7.3
LSD 7.3
androst-4-ene-3,17-dione 7.3
Zwittergent 3-14 7.3
Sodium saccharin 7.2
Androsterone 7.2
DHC 7.2
dipentyl 7.2
Protect 7.1
NADP 7.1
Linuron 7.1
more...