Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.1.1.3 (
HSD
)
3,464
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
HSD
3124
Mol
371
ANOVA
310
HSD1
242
reductase
242
3 beta-HSD
235
HSD2
222
Sep
219
3 beta-hydroxysteroid dehydrogenase
181
P450scc
171
17 beta-hydroxysteroid dehydrogenase
169
aromatase
160
HDL
159
threonine
146
cytochrome P450
144
NAD
142
StAR
136
insulin
125
NADPH
124
P450
117
Leydig cell
109
steroidogenic acute regulatory protein
107
NADP
106
microsomal
99
FSH
98
mineralocorticoid receptor
96
ACTH
88
Gen
80
P450c17
78
glucocorticoid receptor
74
delta 4
71
NADH
71
androgen receptor
70
NAD+
65
CYP11A1
62
17beta-hydroxysteroid dehydrogenase
61
Aromatase
53
NADP+
50
C17
50
HSD-1
50
endoplasmic reticulum
50
cytochrome
49
chorionic gonadotropin
46
oxidoreductase
43
superoxide dismutase
41
aldo-keto reductase
41
CYP17
40
estrogen receptor
39
20 alpha-hydroxysteroid dehydrogenase
37
GSH
36
catalase
35
prolactin
34
progesterone receptor
33
renin
33
spermatozoa
32
CYP17A1
32
beta-endorphin
31
SOD
30
polypeptide
30
HSD3
30
carbonyl reductase
29
caspase-3
29
LSD
29
glutathione peroxidase
28
cytokine
28
follicle-stimulating hormone
26
epididymal
26
proliferating cell nuclear antigen
26
CYP19A1
25
leptin
25
CYP19
24
dimeric
23
CYP11A
22
short-chain dehydrogenase/reductase
22
IL-6
22
fused
21
angiotensin II
20
Bcl-2
20
collagen
20
TNF
20
more...
Disease
hypertension
139
Steroids
89
tumor
78
obesity
74
cancer
61
breast cancer
60
diabetes
53
SEM
40
GSH
35
uterus
32
epididymis
31
polycystic ovary syndrome
30
infertility
29
prostate cancer
27
carcinoma
26
congenital adrenal hyperplasia
25
Cushing's syndrome
24
metabolic syndrome
24
type 2 diabetes
22
depression
21
Testes
20
MCF
19
SDS
18
NSD
16
essential hypertension
15
hypercortisolism
15
glucose intolerance
14
Placenta
14
hyperglycemia
14
choriocarcinoma
14
osteoporosis
14
aldosteronism
14
wasting
13
cholera
13
cold
12
hepatocellular carcinoma
12
IPS
12
adenoma
12
external genitalia
12
endometriosis
12
HCG
11
endometrial cancer
10
Testis
10
Testis
10
testicular dysfunction
10
cardiovascular disease
10
hyperinsulinemia
10
Brown
9
CIE
9
male infertility
9
osteosarcoma
9
seminal vesicles
8
arthritis
8
21-hydroxylase deficiency
8
coronary artery disease
8
dehydration
8
adrenal insufficiency
8
stroke
8
Mycobacterium
8
atherosclerosis
8
hyperlipidemia
8
CAM
8
hyperandrogenism
7
malnutrition
7
Alzheimer's disease
7
anovulation
7
asthma
7
hypogonadism
6
peritonitis
6
adrenal hyperplasia
6
gynecomastia
6
rheumatoid arthritis
6
epithelial ovarian cancer
6
MSD
6
aggression
6
endocrine disorder
6
metabolic disorder
5
preeclampsia
5
lung cancer
5
dyslipidemia
5
more...
Symptom
masculinization
25
fatigue
11
pain
11
anesthesia
10
overweight
4
acidity
4
starvation
4
agitation
3
seizures
3
headache
3
hypothermia
3
acute stress
2
discomfort
2
diarrhea
2
respiratory distress
2
Decreased activity
2
exhaustion
2
polydipsia
2
Cushingoid
2
polyuria
2
dystonia
2
Cushingoid
2
flushing
2
insomnia
1
distraction
1
CSR
1
Tissue sensitivity
1
splenomegaly
1
tremor
1
muscle stiffness
1
HSA
1
male subfertility
1
voice change
1
hepatomegaly
1
loss of balance
1
back pain
1
lethargy
1
thinning
1
discomfort
1
low back pain
1
dysarthria
1
ENT
1
dyspnea
1
dry skin
1
pallor
1
hunger
1
weakness
1
vomiting
1
rhinorrhea
1
snoring
1
knee pain
1
analgesia
1
Balding
1
sciatica
1
physical appearance
1
functional recovery
1
abdominal pain
1
hepatosplenomegaly
1
hypersomnia
1
hypotonia
1
Drug
lysine
83
NADH
71
MAP
46
DHT
31
DHT
31
EE2
26
THF
17
ROS
16
Trilostane
16
Carbenoxolone
15
HCG
11
Dermatol
11
Estrogens
9
ascorbate
9
vitamin E
8
Ethanol
8
CAM
8
Asn
7
Glycyrrhiza
7
Gel
7
Pregnenolone
6
Forskolin
6
Dihydrotestosterone
6
Angiotensin II
5
Ringer's solution
5
Digitalis
5
CTX
5
ICI
5
caffeine
4
DEX
4
ENT
4
Activin
4
IFN-gamma
4
Ketoconazole
3
Rosiglitazone
3
IL-2
3
Lead acetate
3
ZnO
3
Monit
3
Triclosan
3
Luteinizing
2
EPA
2
pyridoxal phosphate
2
R1881
2
lactose
2
Spectrum
2
Furan
2
ACT
2
Posture
2
Vitamin A
2
Spectrum
2
Bifidobacterium
2
Kenyan
2
Xanthium
2
Cardiovasc
2
Leaf
2
balanced salt solution
2
PCB
2
Ethibond
1
Gestrinone
1
CEG
1
Troglitazone
1
Saccharin sodium
1
Growth hormone
1
Gadofosveset trisodium
1
Silica gel
1
Camphor
1
Estriol
1
Zoledronic acid
1
Glutathione
1
EMB
1
Cibacron Blue
1
Parlodel
1
citric acid
1
Adosterol
1
Aztec
1
ROC
1
CEG
1
Nephron
1
MDS
1
more...
Enzyme
HSD
3464
11beta-hydroxysteroid dehydrogenase
355
3beta-hydroxysteroid dehydrogenase
252
aspartokinase
136
17beta-HSD
73
superoxide dismutase
62
17beta-HSD
55
cytochrome P-450scc
54
catalase
52
mitogen-activated protein kinase
39
protein kinase
37
homoserine kinase
36
renin
33
carbonyl reductase
29
glutathione peroxidase
28
ERK
25
protein kinase C
24
glucose-6-phosphate dehydrogenase
23
5alpha-reductase
21
20alpha-hydroxysteroid dehydrogenase
21
5alpha-reductase
21
caspase-3
20
alkaline phosphatase
20
dihydrodipicolinate synthase
20
threonine synthase
20
peroxidase
19
threonine deaminase
17
sulfatase
16
glutathione S-transferase
15
reverse transcriptase
15
glutathione reductase
13
ATPase
13
luciferase
13
21-hydroxylase
13
collagenase
12
3alpha-hydroxysteroid dehydrogenase
12
diaphorase
11
hydroxyprostaglandin dehydrogenase
11
prostaglandin F synthase
10
NADPH-diaphorase
10
NQO1
10
15-hydroxyprostaglandin dehydrogenase
10
AMP-activated protein kinase
10
dihydrodiol dehydrogenase
10
diaphorase
9
RNase
9
RNase
9
adenylate cyclase
9
acid phosphatase
9
lactate dehydrogenase
9
ACE
8
trypsin
8
CAD
8
3beta-HSDH
8
CAD
8
CAD
8
alcohol dehydrogenase
8
RNA polymerase
7
ACS
7
aldose reductase
7
chloramphenicol acetyltransferase
7
lipase
6
AMPK
6
saccharopine dehydrogenase
6
pyruvate carboxylase
6
7alpha-hydroxysteroid dehydrogenase
6
estrogen sulfotransferase
6
CDR
6
AMPK
6
aspartate semialdehyde dehydrogenase
6
PDH
6
gamma-glutamyl transpeptidase
5
focal adhesion kinase
5
transcriptase
5
phosphoenolpyruvate carboxykinase
5
alanine aminotransferase
5
S1 nuclease
5
ribonuclease
5
ribonuclease
5
phosphoenolpyruvate carboxykinase
5
more...
Compound
Dec
279
NAD
197
water
196
NADP
164
threonine
158
sodium
153
Clin
152
NAD
142
DNA
133
aldosterone
131
NADPH
125
NADPH
124
glucose
101
lysine
96
salt
90
ACTH
88
homoserine
76
cAMP
73
NADH
71
phosphate
70
acetate
69
methionine
67
homoserine
65
homoserine
65
oxygen
60
sulfate
60
Ile
52
DHA
50
isoleucine
46
isoleucine
45
Progesterone
44
L-threonine
43
androstane
43
calcium
41
Cortisol
39
ethanol
39
nicotinamide
38
potassium
37
GSH
36
DHT
36
GSH
36
hydrogen
35
Androstenedione
35
Testosterone
32
Testosterone
32
Asp
31
LSD
29
cadmium
26
Estradiol
25
nitric oxide
25
cysteine
24
tyrosine
24
His
23
Dexamethasone
23
SDS
22
zinc
22
aspartic acid
22
TNF
20
MDA
20
alanine
19
COS
19
serine
19
AMP
18
CAT
18
Dextran
18
Adrenal
18
CAT
18
ammonium
18
CAT
18
2-ethylhexyl
17
THF
17
copper
17
2-ethylhexyl
17
THF
17
aluminum
17
2-ethylhexyl
17
titanium
16
methanol
15
ATP
15
phosphoric acid
14
more...