Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.1.1.3 (
HSD
)
3,464
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
HSD
3124
Mol
371
ANOVA
310
reductase
242
HSD1
242
3 beta-HSD
235
HSD2
222
Sep
219
3 beta-hydroxysteroid dehydrogenase
181
P450scc
171
17 beta-hydroxysteroid dehydrogenase
169
aromatase
160
HDL
159
threonine
146
cytochrome P450
144
NAD
142
StAR
136
insulin
125
NADPH
124
P450
117
Leydig cell
109
steroidogenic acute regulatory protein
107
NADP
106
microsomal
99
FSH
98
mineralocorticoid receptor
96
ACTH
88
Gen
80
P450c17
78
glucocorticoid receptor
74
NADH
71
delta 4
71
androgen receptor
70
NAD+
65
CYP11A1
62
17beta-hydroxysteroid dehydrogenase
61
Aromatase
53
endoplasmic reticulum
50
C17
50
HSD-1
50
more...
Disease
hypertension
139
Steroids
89
tumor
78
obesity
74
cancer
61
breast cancer
60
diabetes
53
SEM
40
GSH
35
uterus
32
epididymis
31
polycystic ovary syndrome
30
infertility
29
prostate cancer
27
carcinoma
26
congenital adrenal hyperplasia
25
Cushing's syndrome
24
metabolic syndrome
24
type 2 diabetes
22
depression
21
Testes
20
MCF
19
SDS
18
NSD
16
essential hypertension
15
hypercortisolism
15
choriocarcinoma
14
osteoporosis
14
hyperglycemia
14
Placenta
14
glucose intolerance
14
aldosteronism
14
cholera
13
wasting
13
hepatocellular carcinoma
12
endometriosis
12
IPS
12
external genitalia
12
adenoma
12
cold
12
more...
Symptom
masculinization
25
pain
11
fatigue
11
anesthesia
10
starvation
4
overweight
4
acidity
4
seizures
3
agitation
3
headache
3
hypothermia
3
acute stress
2
flushing
2
discomfort
2
polydipsia
2
exhaustion
2
respiratory distress
2
polyuria
2
Cushingoid
2
dystonia
2
diarrhea
2
Cushingoid
2
Decreased activity
2
insomnia
1
distraction
1
CSR
1
Tissue sensitivity
1
splenomegaly
1
tremor
1
muscle stiffness
1
HSA
1
loss of balance
1
voice change
1
hepatomegaly
1
back pain
1
thinning
1
discomfort
1
lethargy
1
low back pain
1
hunger
1
more...
Drug
lysine
83
NADH
71
MAP
46
DHT
31
DHT
31
EE2
26
THF
17
Trilostane
16
ROS
16
Carbenoxolone
15
Dermatol
11
HCG
11
ascorbate
9
Estrogens
9
vitamin E
8
CAM
8
Ethanol
8
Glycyrrhiza
7
Asn
7
Gel
7
Dihydrotestosterone
6
Pregnenolone
6
Forskolin
6
Ringer's solution
5
CTX
5
ICI
5
Angiotensin II
5
Digitalis
5
caffeine
4
Activin
4
IFN-gamma
4
ENT
4
DEX
4
Ketoconazole
3
Rosiglitazone
3
IL-2
3
Lead acetate
3
ZnO
3
Triclosan
3
Monit
3
more...
Enzyme
HSD
3464
11beta-hydroxysteroid dehydrogenase
355
3beta-hydroxysteroid dehydrogenase
252
aspartokinase
136
17beta-HSD
73
superoxide dismutase
62
17beta-HSD
55
cytochrome P-450scc
54
catalase
52
mitogen-activated protein kinase
39
protein kinase
37
homoserine kinase
36
renin
33
carbonyl reductase
29
glutathione peroxidase
28
ERK
25
protein kinase C
24
glucose-6-phosphate dehydrogenase
23
5alpha-reductase
21
5alpha-reductase
21
20alpha-hydroxysteroid dehydrogenase
21
dihydrodipicolinate synthase
20
alkaline phosphatase
20
threonine synthase
20
caspase-3
20
peroxidase
19
threonine deaminase
17
sulfatase
16
reverse transcriptase
15
glutathione S-transferase
15
glutathione reductase
13
luciferase
13
ATPase
13
21-hydroxylase
13
collagenase
12
3alpha-hydroxysteroid dehydrogenase
12
hydroxyprostaglandin dehydrogenase
11
diaphorase
11
NQO1
10
dihydrodiol dehydrogenase
10
more...
Compound
Dec
279
NAD
197
water
196
NADP
164
threonine
158
sodium
153
Clin
152
NAD
142
DNA
133
aldosterone
131
NADPH
125
NADPH
124
glucose
101
lysine
96
salt
90
ACTH
88
homoserine
76
cAMP
73
NADH
71
phosphate
70
acetate
69
methionine
67
homoserine
65
homoserine
65
oxygen
60
sulfate
60
Ile
52
DHA
50
isoleucine
46
isoleucine
45
Progesterone
44
L-threonine
43
androstane
43
calcium
41
ethanol
39
Cortisol
39
nicotinamide
38
potassium
37
GSH
36
DHT
36
more...