Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.1.1.3 (HSD)
 3,464 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
HSD 3124
Mol 371
ANOVA 310
reductase 242
HSD1 242
3 beta-HSD 235
HSD2 222
Sep 219
3 beta-hydroxysteroid dehydrogenase 181
P450scc 171
17 beta-hydroxysteroid dehydrogenase 169
aromatase 160
HDL 159
threonine 146
cytochrome P450 144
NAD 142
StAR 136
insulin 125
NADPH 124
P450 117
Leydig cell 109
steroidogenic acute regulatory protein 107
NADP 106
microsomal 99
FSH 98
mineralocorticoid receptor 96
ACTH 88
Gen 80
P450c17 78
glucocorticoid receptor 74
NADH 71
delta 4 71
androgen receptor 70
NAD+ 65
CYP11A1 62
17beta-hydroxysteroid dehydrogenase 61
Aromatase 53
HSD-1 50
NADP+ 50
C17 50
endoplasmic reticulum 50
cytochrome 49
chorionic gonadotropin 46
oxidoreductase 43
superoxide dismutase 41
aldo-keto reductase 41
CYP17 40
estrogen receptor 39
20 alpha-hydroxysteroid dehydrogenase 37
GSH 36
catalase 35
prolactin 34
progesterone receptor 33
renin 33
spermatozoa 32
CYP17A1 32
beta-endorphin 31
HSD3 30
SOD 30
polypeptide 30
caspase-3 29
carbonyl reductase 29
LSD 29
cytokine 28
glutathione peroxidase 28
epididymal 26
proliferating cell nuclear antigen 26
follicle-stimulating hormone 26
CYP19A1 25
leptin 25
CYP19 24
dimeric 23
short-chain dehydrogenase/reductase 22
IL-6 22
CYP11A 22
fused 21
Bcl-2 20
collagen 20
angiotensin II 20
TNF 20
gut 19
alkaline phosphatase 19
SDS 18
CAT 18
dihydrodipicolinate synthase 18
Pseudomonas 18
AMP 18
LHRH 17
glucose-6-phosphate dehydrogenase 17
cytochrome P-450 17
NSD 16
ERK1 16
P450c21 16
ROS 16
sulfatase 15
C18 15
insulin-like growth factor 15
thymus 15
21-hydroxylase 15
ATP 15
luteinizing hormone receptor 15
IGF-I 14
lipopolysaccharide 14
DDX 14
STAR 14
membrane-bound 14
IL-4 14
3alpha-HSD 14
xenobiotic 13
steroidogenic factor 1 13
hormone receptor 13
C21 13
glutathione reductase 13
HSD3B2 13
AKR1C3 13
ERK 13
ATPase 12
grit 12
AKR1C1 12
HSD3B1 12
20alpha-hydroxysteroid dehydrogenase 12
LHR 12
SF-1 12
AKR1C2 12
IPS 12
PRL 12
epidermal growth factor 12
peroxidase 12
PKA 12
LDH 11
PGF 11
HCG 11
DHP 11
kit 11
PKC 11
CYP 11
MAPK 11
tumor necrosis factor 11
THP 11
collagenase 11
dihydrodiol dehydrogenase 10
casein 10
collecting duct 10
3-beta-hydroxysteroid dehydrogenase 10
growth hormone 10
membrane protein 10
CYP21 10
ferredoxin 10
CIE 9
IGF-1 9
acid phosphatase 9
albumin 9
HSD17B3 9
ADP 9
mTOR 9
adrenocorticotropic hormone 9
CRH 9
glycoprotein 9
lactate dehydrogenase 9
FSHR 9
more...
Disease
hypertension 139
Steroids 89
tumor 78
obesity 74
cancer 61
breast cancer 60
diabetes 53
SEM 40
GSH 35
uterus 32
epididymis 31
polycystic ovary syndrome 30
infertility 29
prostate cancer 27
carcinoma 26
congenital adrenal hyperplasia 25
Cushing's syndrome 24
metabolic syndrome 24
type 2 diabetes 22
depression 21
Testes 20
MCF 19
SDS 18
NSD 16
hypercortisolism 15
essential hypertension 15
Placenta 14
aldosteronism 14
osteoporosis 14
choriocarcinoma 14
glucose intolerance 14
hyperglycemia 14
cholera 13
wasting 13
hepatocellular carcinoma 12
external genitalia 12
endometriosis 12
cold 12
adenoma 12
IPS 12
HCG 11
Testis 10
cardiovascular disease 10
hyperinsulinemia 10
endometrial cancer 10
testicular dysfunction 10
Testis 10
Brown 9
male infertility 9
osteosarcoma 9
CIE 9
adrenal insufficiency 8
atherosclerosis 8
dehydration 8
Mycobacterium 8
hyperlipidemia 8
stroke 8
arthritis 8
21-hydroxylase deficiency 8
coronary artery disease 8
seminal vesicles 8
CAM 8
hyperandrogenism 7
Alzheimer's disease 7
anovulation 7
malnutrition 7
asthma 7
aggression 6
epithelial ovarian cancer 6
gynecomastia 6
MSD 6
rheumatoid arthritis 6
hypogonadism 6
endocrine disorder 6
peritonitis 6
adrenal hyperplasia 6
tumorigenesis 5
cholestasis 5
metabolic disorder 5
adrenocortical carcinoma 5
preeclampsia 5
ovarian cancer 5
ACP 5
carcinogenesis 5
HPA 5
BDE 5
vagina 5
NAME 5
abortion 5
ovarian dysfunction 5
celiac disease 5
renal disease 5
mammary tumor 5
lung cancer 5
dyslipidemia 5
endometrial hyperplasia 5
Evans 5
posttraumatic stress disorder 4
B-cell lymphoma 4
HSP 4
Leydig cell hyperplasia 4
Cushing's disease 4
ICP 4
gallstones 4
hypothyroidism 4
heart failure 4
West 4
fungal infection 4
premenstrual syndrome 4
Adenovirus 4
sepsis 4
glioma 4
squamous cell carcinoma 4
epilepsy 4
adenocarcinoma 4
PMS 4
EIA 4
hypernatremia 4
sepsis 4
ductal carcinoma 4
WT1 4
chronic renal failure 4
fatty liver 4
liver disease 4
cirrhosis 4
alcoholism 3
enzyme deficiency 3
Disorder 3
tumor growth 3
STS 3
delayed puberty 3
dysplasia 3
acne 3
proteinuria 3
cervical cancer 3
APC 3
neoplastic transformation 3
Liddle's syndrome 3
major depressive disorder 3
Ehlers-Danlos syndrome 3
Ovary 3
schizophrenia 3
acromegaly 3
vaccinia 3
cognitive impairment 3
dysphagia 3
ductal carcinoma in situ 3
tumor progression 3
suicide 3
HOS 3
hypercholesterolemia 3
colon cancer 3
Syndrome 3
mole 3
mole 3
nephrotic syndrome 3
chronic active hepatitis 3
infectious diseases 3
coagulopathy 3
primary sclerosing cholangitis 3
more...
Symptom
masculinization 25
fatigue 11
pain 11
anesthesia 10
overweight 4
acidity 4
starvation 4
agitation 3
seizures 3
headache 3
hypothermia 3
acute stress 2
discomfort 2
diarrhea 2
respiratory distress 2
Decreased activity 2
exhaustion 2
polydipsia 2
Cushingoid 2
polyuria 2
dystonia 2
Cushingoid 2
flushing 2
insomnia 1
distraction 1
CSR 1
Tissue sensitivity 1
splenomegaly 1
tremor 1
muscle stiffness 1
HSA 1
male subfertility 1
voice change 1
hepatomegaly 1
loss of balance 1
back pain 1
lethargy 1
thinning 1
discomfort 1
low back pain 1
dysarthria 1
ENT 1
dyspnea 1
dry skin 1
pallor 1
hunger 1
weakness 1
vomiting 1
rhinorrhea 1
snoring 1
knee pain 1
analgesia 1
Balding 1
sciatica 1
physical appearance 1
functional recovery 1
abdominal pain 1
hepatosplenomegaly 1
hypersomnia 1
hypotonia 1
Drug
lysine 83
NADH 71
MAP 46
DHT 31
DHT 31
EE2 26
THF 17
Trilostane 16
ROS 16
Carbenoxolone 15
Dermatol 11
HCG 11
Estrogens 9
ascorbate 9
CAM 8
Ethanol 8
vitamin E 8
Gel 7
Asn 7
Glycyrrhiza 7
Pregnenolone 6
Forskolin 6
Dihydrotestosterone 6
ICI 5
CTX 5
Ringer's solution 5
Digitalis 5
Angiotensin II 5
ENT 4
DEX 4
IFN-gamma 4
Activin 4
caffeine 4
Rosiglitazone 3
Monit 3
IL-2 3
Triclosan 3
ZnO 3
Lead acetate 3
Ketoconazole 3
Spectrum 2
pyridoxal phosphate 2
R1881 2
lactose 2
balanced salt solution 2
Leaf 2
Cardiovasc 2
Xanthium 2
Furan 2
Vitamin A 2
Spectrum 2
Bifidobacterium 2
Posture 2
Kenyan 2
Luteinizing 2
ACT 2
PCB 2
EPA 2
Retinoic acid 1
Ethibond 1
Paraffin 1
PTH 1
Gestrinone 1
Primaquine 1
HCH 1
FSH-beta 1
Saccharin sodium 1
Troglitazone 1
Sulphasalazine 1
Gadofosveset trisodium 1
Silica gel 1
Fosmidomycin 1
TAK 1
MRC 1
Zoledronic acid 1
Captopril 1
Glutathione 1
EMB 1
Cibacron Blue 1
Parlodel 1
citric acid 1
Adosterol 1
L-tyrosine 1
Aztec 1
SrCl2 1
Bear bile 1
Nephron 1
KCL 1
ROC 1
CEG 1
Azithromycin 1
Ketorolac tromethamine 1
Indomethacin 1
Tenoxicam 1
Almora 1
MDS 1
RSM 1
Rimonabant 1
Apomorphine 1
Florisil 1
Arimidex 1
Modafinil 1
FSH-beta 1
Benzofuran 1
AGG 1
Vitamin-E 1
CTX 1
Clodronate 1
SrCl2 1
Peridex 1
FSH-beta 1
Ganaxolone 1
Camphor 1
Vitamin B12 1
Cortrosyn 1
Ciprofibrate 1
NH3 1
TTC 1
Award 1
CSF 1
Tween 40 1
THA 1
CTX 1
Aicar 1
Fructose 1
Cortrosyn 1
CEG 1
Cimetidine 1
Vitamin E 1
Phosphagen 1
Cimetidine 1
Prednisolone 1
Growth hormone 1
Factrel 1
Camphor 1
Growth hormone 1
Clomiphene citrate 1
Calcium silicate 1
Zmax 1
Estriol 1
Alarin 1
Dutasteride 1
Arsenic trioxide 1
ATV 1
Ketorolac 1
Leucovorin 1
Enzyme
HSD 3464
11beta-hydroxysteroid dehydrogenase 355
3beta-hydroxysteroid dehydrogenase 252
aspartokinase 136
17beta-HSD 73
superoxide dismutase 62
17beta-HSD 55
cytochrome P-450scc 54
catalase 52
mitogen-activated protein kinase 39
protein kinase 37
homoserine kinase 36
renin 33
carbonyl reductase 29
glutathione peroxidase 28
ERK 25
protein kinase C 24
glucose-6-phosphate dehydrogenase 23
5alpha-reductase 21
20alpha-hydroxysteroid dehydrogenase 21
5alpha-reductase 21
caspase-3 20
threonine synthase 20
dihydrodipicolinate synthase 20
alkaline phosphatase 20
peroxidase 19
threonine deaminase 17
sulfatase 16
reverse transcriptase 15
glutathione S-transferase 15
21-hydroxylase 13
luciferase 13
glutathione reductase 13
ATPase 13
collagenase 12
3alpha-hydroxysteroid dehydrogenase 12
hydroxyprostaglandin dehydrogenase 11
diaphorase 11
prostaglandin F synthase 10
15-hydroxyprostaglandin dehydrogenase 10
NADPH-diaphorase 10
AMP-activated protein kinase 10
NQO1 10
dihydrodiol dehydrogenase 10
diaphorase 9
acid phosphatase 9
RNase 9
adenylate cyclase 9
lactate dehydrogenase 9
RNase 9
CAD 8
CAD 8
ACE 8
trypsin 8
CAD 8
3beta-HSDH 8
alcohol dehydrogenase 8
RNA polymerase 7
aldose reductase 7
ACS 7
chloramphenicol acetyltransferase 7
AMPK 6
estrogen sulfotransferase 6
AMPK 6
aspartate semialdehyde dehydrogenase 6
7alpha-hydroxysteroid dehydrogenase 6
saccharopine dehydrogenase 6
lipase 6
CDR 6
pyruvate carboxylase 6
PDH 6
focal adhesion kinase 5
prostaglandin synthetase 5
alanine aminotransferase 5
ribonuclease 5
ribonuclease 5
phosphoenolpyruvate carboxykinase 5
glyceraldehyde-3-phosphate dehydrogenase 5
S1 nuclease 5
phospholipase A2 5
phosphoenolpyruvate carboxykinase 5
phosphoenolpyruvate carboxykinase 5
glyceraldehyde-3-phosphate dehydrogenase 5
gamma-glutamyl transpeptidase 5
transcriptase 5
20beta-hydroxysteroid dehydrogenase 4
aldehyde reductase 4
glyceraldehyde-3-phosphate dehydrogenase 4
arylsulfatase 4
MDR 4
aldehyde reductase 4
estrogen sulfotransferase 4
PARP 4
6-phosphogluconate dehydrogenase 4
phosphoinositide 3-kinase 4
cdc2 4
proteasome 4
6-phosphogluconate dehydrogenase 4
subtilisin 4
CPR 4
aspartate aminotransferase 4
glucose dehydrogenase 4
glyceraldehyde-3-phosphate dehydrogenase 4
glyceraldehyde-3-phosphate dehydrogenase 4
aldehyde reductase 4
5beta-reductase 4
diaminopimelate dehydrogenase 3
EC 1.1.1.201 3
glutamate dehydrogenase 3
hydrogenase 3
glutamate dehydrogenase 3
hydrogenase 3
beta-glucuronidase 3
chymotrypsin 3
tyrosine hydroxylase 3
APC 3
sorbitol dehydrogenase 3
MAP 3
phosphofructokinase 3
aldehyde dehydrogenase 3
NOS 3
creatine kinase 3
ATP synthase 3
acetolactate synthase 3
phospholipase C 3
lipoprotein lipase 3
dihydrodipicolinate reductase 3
nitrate reductase 2
phosphoserine phosphatase 2
nitrate reductase 2
ecdysone 20-monooxygenase 2
threonine dehydrogenase 2
nitrate reductase 2
glutamate synthase 2
glutamate synthase 2
phenylethanolamine N-methyltransferase 2
chalcone synthase 2
NO synthase 2
alpha-amylase 2
glutamate dehydrogenase 2
PRA 2
ATP sulfurylase 2
nitrate reductase 2
NADPH oxidase 2
caspase-1 2
monoamine oxidase 2
nitrate reductase 2
DNA methyltransferase 2
thrombin 2
lipoxygenase 2
glucokinase 2
NADPH oxidase 2
thromboplastin 2
PST 2
deaminase 2
guanylate cyclase 2
MEK 2
3-KSR 2
homoserine transacetylase 2
CYP3A4 2
more...
Compound
Dec 279
NAD 197
water 196
NADP 164
threonine 158
sodium 153
Clin 152
NAD 142
DNA 133
aldosterone 131
NADPH 125
NADPH 124
glucose 101
lysine 96
salt 90
ACTH 88
homoserine 76
cAMP 73
NADH 71
phosphate 70
acetate 69
methionine 67
homoserine 65
homoserine 65
sulfate 60
oxygen 60
Ile 52
DHA 50
isoleucine 46
isoleucine 45
Progesterone 44
androstane 43
L-threonine 43
calcium 41
Cortisol 39
ethanol 39
nicotinamide 38
potassium 37
GSH 36
GSH 36
DHT 36
hydrogen 35
Androstenedione 35
Testosterone 32
Testosterone 32
Asp 31
LSD 29
cadmium 26
Estradiol 25
nitric oxide 25
tyrosine 24
cysteine 24
Dexamethasone 23
His 23
SDS 22
zinc 22
aspartic acid 22
TNF 20
MDA 20
COS 19
serine 19
alanine 19
CAT 18
AMP 18
CAT 18
Dextran 18
CAT 18
Adrenal 18
ammonium 18
2-ethylhexyl 17
copper 17
2-ethylhexyl 17
2-ethylhexyl 17
THF 17
THF 17
aluminum 17
titanium 16
methanol 15
ATP 15
phosphoric acid 14
arginine 14
DEHP 14
DEAE 13
Androgen 13
urea 13
Phe 13
nitrogen 13
valine 13
aspartic acid 13
noradrenaline 12
galactose 12
MTT 12
THP 11
Vitamin D 11
THE 11
glycerol 11
ADP 11
Salt 11
THP 11
17-OHP 10
Insulin 10
aldehyde 10
glutamate 10
pyridine 10
silver 10
Glycyrrhizin 10
PGE2 9
aspartic acid 9
Corticosterone 9
tryptophan 9
fluorine 9
nitrate 9
H2O2 9
DHA 9
ADP 9
DHA 9
silicon 9
nickel 9
tryptophan 9
Glycyrrhetinic acid 9
retinoic acid 9
tryptophan 9
aldehyde 9
bromide 9
ADP 9
tryptophan 9
aspartic acid 9
DBP 8
leucine 8
ClO 8
Cholesterol 8
CAM 8
EDTA 8
creatinine 8
EDTA 8
Glycyrrhetinic acid 8
pyrene 8
manganese 8
iron 8
Bisphenol A 8
Bisphenol A 8
phosphorus 8
ACS 7
GABA 7
NH2 7
sodium chloride 7
GABA 7
prostaglandin F2alpha 7
CO2 7
selenium 7
acetone 7
Gly 7
hydroxide 7
Estrogen 7
ACS 7
DBP 7
MTA 7
Arsenic 7
A 1 7
DMSO 7
more...