Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:1.1.1.3 (HSD)
 3,464 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The aim of this study was to compare the effects of nasal splinting during different modes of breathing on breathing patterns and cardiorespiratory responses. Ten healthy subjects (4 males, 6 females) performed five maximal treadmill tests while breathing through the nose, nose + dilator, mouth, nose + mouth, and nose + mouth + dilator. Repeated-measures analysis of variance and Tukey HSD revealed no significant differences between trials for maximal oxygen consumption, minute ventilation at an oxygen consumption of 30 ml.kg-1.min-1, carbon dioxide production, respiratory exchange ratio, tidal volume, dead space to tidal volume ratio, or completed treadmill stages to exhaustion. No significant difference was found in subjective dyspnoea ratings between stages of nose versus nose + dilator breathing. Minute ventilation, ventilatory equivalent for oxygen, and breath frequency for nose and nose + dilator versus mouth, nose + mouth, and nose + mouth + dilator were significantly lower. Ventilatory equivalent for carbon dioxide was significantly lower for nose versus mouth, and nose + dilator versus nose + mouth + dilator breathing. End-tidal carbon dioxide was significantly higher in nose versus mouth, nose + mouth, and nose + mouth + dilator breathing, and in nose + dilator versus mouth breathing. Nose breathing revealed a significantly lower heart rate versus nose + dilator, mouth, nose + mouth, and nose + mouth + dilator breathing. These results suggest that nasal splinting during exercise has minimal effects when nasal breathing and no effects when oronasal breathing.
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PMID:Nasal splinting effects on breathing patterns and cardiorespiratory responses. 1040 93