Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.1.1.27 (lactate dehydrogenase)
29,211 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
lactate dehydrogenase 26213
aspartate aminotransferase 2402
creatine kinase 2389
alkaline phosphatase 2274
Sep 2007
superoxide dismutase 1959
catalase 1451
alanine aminotransferase 1400
Mol 1393
ATP 1332
LDH 1274
caspase-3 1181
GSH 1178
albumin 1085
NADH 987
glutathione peroxidase 971
hemoglobin 822
malate dehydrogenase 717
pyruvate kinase 664
NAD 659
tumor necrosis factor 659
acid phosphatase 659
glucose-6-phosphate dehydrogenase 595
TNF 554
citrate synthase 549
hexokinase 520
Bcl-2 515
C-reactive protein 483
insulin 462
cytokine 435
ATPase 400
phosphofructokinase 399
glutathione reductase 399
IL-6 392
L-lactate dehydrogenase 362
collagen 351
lipopolysaccharide 348
beta-glucuronidase 323
myeloperoxidase 312
glutamate dehydrogenase 310
serum albumin 310
NAD+ 296
ADP 287
acetylcholinesterase 287
amylase 283
interleukin-6 273
cytochrome c 263
myoglobin 253
lactic acid dehydrogenase 249
alcohol dehydrogenase 248
p53 246
LDH-A 240
isocitrate dehydrogenase 240
AMP 237
ferritin 233
inducible nitric oxide synthase 225
glyceraldehyde-3-phosphate dehydrogenase 223
endoplasmic reticulum 217
annexin V 205
xanthine oxidase 202
nitric oxide synthase 201
glutathione S-transferase 200
cytochrome 199
p38 193
NADPH 193
AST 192
haptoglobin 187
SOD 184
antioxidant enzyme 183
gamma-glutamyltransferase 183
gamma-glutamyl transpeptidase 182
lysozyme 180
non-Hodgkin's lymphoma 180
heme oxygenase-1 177
reductase 176
pyruvate dehydrogenase 171
ROS 171
NMR 168
kit 161
caspase-9 161
more...
Disease
cancer 1819
tumor 1527
ischemia 1386
GSH 1179
lymphoma 637
myocardial infarction 491
myocardial ischemia 415
diabetes 392
anemia 375
B-cell lymphoma 336
cold 322
thrombocytopenia 316
leukemia 292
carcinoma 284
acute myocardial infarction 283
Alzheimer's disease 265
metastases 261
stroke 248
melanoma 243
hepatocellular carcinoma 237
malaria 212
non-Hodgkin's lymphoma 212
hypertension 208
breast cancer 208
multiple myeloma 199
neuroblastoma 197
Hodgkin's disease 196
pneumonia 185
lung cancer 169
sepsis 169
depression 164
cerebral ischemia 163
lymphadenopathy 154
sepsis 153
hemolytic anemia 144
heart failure 144
adenocarcinoma 138
acute myeloid leukemia 135
atherosclerosis 133
Parkinson's disease 130
infectious diseases 121
MCF 118
acute renal failure 117
tumor growth 116
sickle cell disease 116
hyperglycemia 116
renal failure 114
Epstein 112
hepatitis 110
acute lymphoblastic leukemia 107
proteinuria 105
HIV 105
thrombocytopenic purpura 104
myopathy 103
prostate cancer 103
obesity 100
carcinogenesis 95
SDS 95
pheochromocytoma 95
tuberculosis 93
cardiovascular disease 92
cardiomyopathy 89
liver disease 88
SEM 88
chronic lymphocytic leukemia 85
renal disease 85
NAME 85
metastatic melanoma 84
glioma 84
cirrhosis 84
colorectal cancer 79
AIDS 76
immunodeficiency 75
acute pancreatitis 74
SARS 73
respiratory failure 71
Infection 71
colon cancer 70
Melanoma 69
T-cell lymphoma 69
more...
Symptom
fatigue 263
pain 183
weakness 137
dyspnea 129
anesthesia 112
cough 111
splenomegaly 107
diarrhea 103
abdominal pain 88
hepatosplenomegaly 83
functional recovery 81
hypothermia 74
myalgia 73
chest pain 70
collapse 68
hepatomegaly 68
exhaustion 67
anorexia 66
vomiting 63
respiratory distress 63
hyperoxia 62
seizures 60
headache 57
starvation 46
nausea 46
angina 37
shortness of breath 27
Ill 27
back pain 26
bone pain 25
erythema 23
lethargy 23
nausea and vomiting 21
pallor 21
agitation 21
arthralgia 21
fever of unknown origin 21
tremor 21
chills 19
skin damage 18
polyuria 17
oliguria 16
constipation 16
Anoxia 15
night sweats 15
ataxia 15
dizziness 15
discomfort 13
asthenia 13
flank pain 13
discomfort 13
acidity 12
hypoproteinemia 12
skin irritation 12
regurgitation 11
overweight 11
exertional dyspnea 11
low back pain 10
HSA 10
tachypnea 9
sore throat 9
insomnia 9
paresthesia 8
acute stress 8
hypercapnia 7
hypotonia 7
sleepiness 6
syncope 6
emaciation 6
analgesia 6
cachexia 6
muscle rigidity 6
abdominal discomfort 6
flushing 6
dark urine 6
polydipsia 6
paresis 5
blurred vision 5
Decreased activity 5
muscle stiffness 5
more...
Drug
NADH 1014
Cardiovasc 240
ascorbate 224
vitamin E 224
ROS 171
lysine 112
Dermatol 103
citric acid 74
Ethanol 72
lactose 65
IL-2 61
CSF 59
Glutathione 58
Monit 52
IFN-gamma 47
Adriamycin 46
CTX 45
Vitamin E 42
Albumin 41
Gel 41
Leaf 41
ZnO 39
Indomethacin 34
MAP 33
TiO2 33
caffeine 29
Rituximab 28
FAD 28
Nephron 28
Alanine 27
SiO2 24
Fructose 22
ROC 21
Silica 21
TTC 21
Bifidobacterium 21
balanced salt solution 20
Nephron 20
ICI 20
Cibacron Blue 20
MRC 18
Histamine 18
Ginseng 17
Fluorescein 17
Asn 17
HCG 16
Serum albumin 15
Heme 15
ALA 15
ampicillin 14
Captopril 14
EE2 14
Ouabain 14
Dial 13
Ringer's solution 13
NAG 13
Eculizumab 13
nitroglycerin 12
Vitamin K 12
Glycyrrhiza 12
ABC 12
Arsenic trioxide 11
Mutagen 11
PCB 11
Adenosine triphosphate 11
niacin 10
Triclosan 10
NBT 10
Aloe 10
Glycerol 10
Glucagon 10
Portal 10
ADR 10
CaCl2 9
Emodin 9
FeCl3 9
CaCl2 9
CaCl2 9
Emodin 9
pyridoxal phosphate 9
more...
Enzyme
lactate dehydrogenase 29211
creatine kinase 3041
aspartate aminotransferase 2637
alkaline phosphatase 2278
superoxide dismutase 2062
alanine aminotransferase 2024
catalase 1499
glutathione peroxidase 986
caspase-3 937
malate dehydrogenase 804
glucose-6-phosphate dehydrogenase 691
pyruvate kinase 664
acid phosphatase 660
lactic acid dehydrogenase 630
succinate dehydrogenase 625
gamma-glutamyl transpeptidase 579
citrate synthase 572
hexokinase 522
ATPase 508
peroxidase 479
acetylcholinesterase 429
phosphofructokinase 419
mitogen-activated protein kinase 412
glutathione reductase 407
aldolase 381
glutamate dehydrogenase 328
glutamate dehydrogenase 327
glutamate dehydrogenase 325
glyceraldehyde-3-phosphate dehydrogenase 317
beta-glucuronidase 311
lactic acid dehydrogenase 307
lactic acid dehydrogenase 294
alcohol dehydrogenase 287
glyceraldehyde-3-phosphate dehydrogenase 277
isocitrate dehydrogenase 270
pyruvate dehydrogenase 260
glutathione S-transferase 260
glyceraldehyde-3-phosphate dehydrogenase 248
isocitrate dehydrogenase 248
protein kinase 247
glyceraldehyde-3-phosphate dehydrogenase 238
glyceraldehyde-3-phosphate dehydrogenase 223
xanthine oxidase 205
cholinesterase 201
cytochrome oxidase 199
phosphorylase 198
AST 190
ERK 189
lysozyme 185
diaphorase 182
pyruvate dehydrogenase 173
pyruvate dehydrogenase 171
glycerol-3-phosphate dehydrogenase 166
protein kinase C 166
glycerol-3-phosphate dehydrogenase 164
phosphoglucose isomerase 153
succinic dehydrogenase 151
enolase 147
NQO1 146
glucose-6-phosphatase 138
sorbitol dehydrogenase 137
luciferase 134
caspase-9 125
PARP 123
trypsin 122
6-phosphogluconate dehydrogenase 121
6-phosphogluconate dehydrogenase 121
lipase 121
adenylate kinase 120
collagenase 116
thrombin 116
phosphoenolpyruvate carboxykinase 112
phosphoenolpyruvate carboxykinase 110
phosphoenolpyruvate carboxykinase 109
complex I 104
phospholipase A2 97
leucine aminopeptidase 96
ACE 96
AMP-activated protein kinase 92
NADPH-diaphorase 91
more...
Compound
oxygen 3104
glucose 2920
Dec 2021
DNA 1686
calcium 1659
Clin 1607
ATP 1333
creatinine 1247
GSH 1223
GSH 1223
sodium 1172
urea 1142
water 1119
NADH 1012
phosphate 977
NAD 927
MTT 924
nitric oxide 764
nitrogen 716
glutamate 701
NAD 659
bromide 650
potassium 638
hydrogen 599
TNF 554
ethanol 539
acetate 530
iron 528
alanine 477
Lactate 477
iodine 393
H2O2 354
zinc 324
ADP 320
arginine 316
nicotinamide 315
cysteine 296
sulfate 290
ADP 288
ADP 287
salt 269
His 264
copper 255
AMP 253
alcohol dehydrogenase 252
CO2 249
phosphorus 231
cadmium 221
galactose 221
glycerol 206
MDA 204
NADPH 197
NADPH 193
Cardiol 192
NADP 184
leucine 181
PEG 181
CoA 159
glutamine 154
lysine 148
N-acetylcysteine 148
nitrate 145
Adriamycin 145
dUTP 142
pentose 138
pentose 137
pentose 137
pentose 137
cAMP 136
methionine 134
ammonia 134
oxalate 132
selenium 131
PEG 127
ammonium 127
CCl4 126
serine 124
Phe 123
GSSG 121
Mg2+ 117
more...