Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:1.1.1.27 (
lactate dehydrogenase
)
29,211
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
lactate dehydrogenase
26213
aspartate aminotransferase
2402
creatine kinase
2389
alkaline phosphatase
2274
Sep
2007
superoxide dismutase
1959
catalase
1451
alanine aminotransferase
1400
Mol
1393
ATP
1332
LDH
1274
caspase-3
1181
GSH
1178
albumin
1085
NADH
987
glutathione peroxidase
971
hemoglobin
822
malate dehydrogenase
717
pyruvate kinase
664
NAD
659
tumor necrosis factor
659
acid phosphatase
659
glucose-6-phosphate dehydrogenase
595
TNF
554
citrate synthase
549
hexokinase
520
Bcl-2
515
C-reactive protein
483
insulin
462
cytokine
435
ATPase
400
phosphofructokinase
399
glutathione reductase
399
IL-6
392
L-lactate dehydrogenase
362
collagen
351
lipopolysaccharide
348
beta-glucuronidase
323
myeloperoxidase
312
glutamate dehydrogenase
310
serum albumin
310
NAD+
296
ADP
287
acetylcholinesterase
287
amylase
283
interleukin-6
273
cytochrome c
263
myoglobin
253
lactic acid dehydrogenase
249
alcohol dehydrogenase
248
p53
246
LDH-A
240
isocitrate dehydrogenase
240
AMP
237
ferritin
233
inducible nitric oxide synthase
225
glyceraldehyde-3-phosphate dehydrogenase
223
endoplasmic reticulum
217
annexin V
205
xanthine oxidase
202
nitric oxide synthase
201
glutathione S-transferase
200
cytochrome
199
p38
193
NADPH
193
AST
192
haptoglobin
187
SOD
184
antioxidant enzyme
183
gamma-glutamyltransferase
183
gamma-glutamyl transpeptidase
182
lysozyme
180
non-Hodgkin's lymphoma
180
heme oxygenase-1
177
reductase
176
pyruvate dehydrogenase
171
ROS
171
NMR
168
kit
161
caspase-9
161
more...
Disease
cancer
1819
tumor
1527
ischemia
1386
GSH
1179
lymphoma
637
myocardial infarction
491
myocardial ischemia
415
diabetes
392
anemia
375
B-cell lymphoma
336
cold
322
thrombocytopenia
316
leukemia
292
carcinoma
284
acute myocardial infarction
283
Alzheimer's disease
265
metastases
261
stroke
248
melanoma
243
hepatocellular carcinoma
237
malaria
212
non-Hodgkin's lymphoma
212
hypertension
208
breast cancer
208
multiple myeloma
199
neuroblastoma
197
Hodgkin's disease
196
pneumonia
185
lung cancer
169
sepsis
169
depression
164
cerebral ischemia
163
lymphadenopathy
154
sepsis
153
hemolytic anemia
144
heart failure
144
adenocarcinoma
138
acute myeloid leukemia
135
atherosclerosis
133
Parkinson's disease
130
infectious diseases
121
MCF
118
acute renal failure
117
tumor growth
116
sickle cell disease
116
hyperglycemia
116
renal failure
114
Epstein
112
hepatitis
110
acute lymphoblastic leukemia
107
proteinuria
105
HIV
105
thrombocytopenic purpura
104
myopathy
103
prostate cancer
103
obesity
100
carcinogenesis
95
SDS
95
pheochromocytoma
95
tuberculosis
93
cardiovascular disease
92
cardiomyopathy
89
liver disease
88
SEM
88
chronic lymphocytic leukemia
85
renal disease
85
NAME
85
metastatic melanoma
84
glioma
84
cirrhosis
84
colorectal cancer
79
AIDS
76
immunodeficiency
75
acute pancreatitis
74
SARS
73
respiratory failure
71
Infection
71
colon cancer
70
Melanoma
69
T-cell lymphoma
69
more...
Symptom
fatigue
263
pain
183
weakness
137
dyspnea
129
anesthesia
112
cough
111
splenomegaly
107
diarrhea
103
abdominal pain
88
hepatosplenomegaly
83
functional recovery
81
hypothermia
74
myalgia
73
chest pain
70
collapse
68
hepatomegaly
68
exhaustion
67
anorexia
66
vomiting
63
respiratory distress
63
hyperoxia
62
seizures
60
headache
57
starvation
46
nausea
46
angina
37
shortness of breath
27
Ill
27
back pain
26
bone pain
25
erythema
23
lethargy
23
nausea and vomiting
21
pallor
21
agitation
21
arthralgia
21
fever of unknown origin
21
tremor
21
chills
19
skin damage
18
polyuria
17
oliguria
16
constipation
16
Anoxia
15
night sweats
15
ataxia
15
dizziness
15
discomfort
13
asthenia
13
flank pain
13
discomfort
13
acidity
12
hypoproteinemia
12
skin irritation
12
regurgitation
11
overweight
11
exertional dyspnea
11
low back pain
10
HSA
10
tachypnea
9
sore throat
9
insomnia
9
paresthesia
8
acute stress
8
hypercapnia
7
hypotonia
7
sleepiness
6
syncope
6
emaciation
6
analgesia
6
cachexia
6
muscle rigidity
6
abdominal discomfort
6
flushing
6
dark urine
6
polydipsia
6
paresis
5
blurred vision
5
Decreased activity
5
muscle stiffness
5
more...
Drug
NADH
1014
Cardiovasc
240
ascorbate
224
vitamin E
224
ROS
171
lysine
112
Dermatol
103
citric acid
74
Ethanol
72
lactose
65
IL-2
61
CSF
59
Glutathione
58
Monit
52
IFN-gamma
47
Adriamycin
46
CTX
45
Vitamin E
42
Albumin
41
Gel
41
Leaf
41
ZnO
39
Indomethacin
34
MAP
33
TiO2
33
caffeine
29
Rituximab
28
FAD
28
Nephron
28
Alanine
27
SiO2
24
Fructose
22
ROC
21
Silica
21
TTC
21
Bifidobacterium
21
balanced salt solution
20
Nephron
20
ICI
20
Cibacron Blue
20
MRC
18
Histamine
18
Ginseng
17
Fluorescein
17
Asn
17
HCG
16
Serum albumin
15
Heme
15
ALA
15
ampicillin
14
Captopril
14
EE2
14
Ouabain
14
Dial
13
Ringer's solution
13
NAG
13
Eculizumab
13
nitroglycerin
12
Vitamin K
12
Glycyrrhiza
12
ABC
12
Arsenic trioxide
11
Mutagen
11
PCB
11
Adenosine triphosphate
11
niacin
10
Triclosan
10
NBT
10
Aloe
10
Glycerol
10
Glucagon
10
Portal
10
ADR
10
CaCl2
9
Emodin
9
FeCl3
9
CaCl2
9
CaCl2
9
Emodin
9
pyridoxal phosphate
9
more...
Enzyme
lactate dehydrogenase
29211
creatine kinase
3041
aspartate aminotransferase
2637
alkaline phosphatase
2278
superoxide dismutase
2062
alanine aminotransferase
2024
catalase
1499
glutathione peroxidase
986
caspase-3
937
malate dehydrogenase
804
glucose-6-phosphate dehydrogenase
691
pyruvate kinase
664
acid phosphatase
660
lactic acid dehydrogenase
630
succinate dehydrogenase
625
gamma-glutamyl transpeptidase
579
citrate synthase
572
hexokinase
522
ATPase
508
peroxidase
479
acetylcholinesterase
429
phosphofructokinase
419
mitogen-activated protein kinase
412
glutathione reductase
407
aldolase
381
glutamate dehydrogenase
328
glutamate dehydrogenase
327
glutamate dehydrogenase
325
glyceraldehyde-3-phosphate dehydrogenase
317
beta-glucuronidase
311
lactic acid dehydrogenase
307
lactic acid dehydrogenase
294
alcohol dehydrogenase
287
glyceraldehyde-3-phosphate dehydrogenase
277
isocitrate dehydrogenase
270
pyruvate dehydrogenase
260
glutathione S-transferase
260
glyceraldehyde-3-phosphate dehydrogenase
248
isocitrate dehydrogenase
248
protein kinase
247
glyceraldehyde-3-phosphate dehydrogenase
238
glyceraldehyde-3-phosphate dehydrogenase
223
xanthine oxidase
205
cholinesterase
201
cytochrome oxidase
199
phosphorylase
198
AST
190
ERK
189
lysozyme
185
diaphorase
182
pyruvate dehydrogenase
173
pyruvate dehydrogenase
171
glycerol-3-phosphate dehydrogenase
166
protein kinase C
166
glycerol-3-phosphate dehydrogenase
164
phosphoglucose isomerase
153
succinic dehydrogenase
151
enolase
147
NQO1
146
glucose-6-phosphatase
138
sorbitol dehydrogenase
137
luciferase
134
caspase-9
125
PARP
123
trypsin
122
6-phosphogluconate dehydrogenase
121
6-phosphogluconate dehydrogenase
121
lipase
121
adenylate kinase
120
collagenase
116
thrombin
116
phosphoenolpyruvate carboxykinase
112
phosphoenolpyruvate carboxykinase
110
phosphoenolpyruvate carboxykinase
109
complex I
104
phospholipase A2
97
leucine aminopeptidase
96
ACE
96
AMP-activated protein kinase
92
NADPH-diaphorase
91
more...
Compound
oxygen
3104
glucose
2920
Dec
2021
DNA
1686
calcium
1659
Clin
1607
ATP
1333
creatinine
1247
GSH
1223
GSH
1223
sodium
1172
urea
1142
water
1119
NADH
1012
phosphate
977
NAD
927
MTT
924
nitric oxide
764
nitrogen
716
glutamate
701
NAD
659
bromide
650
potassium
638
hydrogen
599
TNF
554
ethanol
539
acetate
530
iron
528
alanine
477
Lactate
477
iodine
393
H2O2
354
zinc
324
ADP
320
arginine
316
nicotinamide
315
cysteine
296
sulfate
290
ADP
288
ADP
287
salt
269
His
264
copper
255
AMP
253
alcohol dehydrogenase
252
CO2
249
phosphorus
231
cadmium
221
galactose
221
glycerol
206
MDA
204
NADPH
197
NADPH
193
Cardiol
192
NADP
184
leucine
181
PEG
181
CoA
159
glutamine
154
lysine
148
N-acetylcysteine
148
nitrate
145
Adriamycin
145
dUTP
142
pentose
138
pentose
137
pentose
137
pentose
137
cAMP
136
methionine
134
ammonia
134
oxalate
132
selenium
131
PEG
127
ammonium
127
CCl4
126
serine
124
Phe
123
GSSG
121
Mg2+
117
more...