Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.1.1.21 (aldose reductase)
3,305 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
aldose reductase 0.871
aldehyde reductase 0.147
ALR2 0.057
Aldose reductase 0.045
sorbitol dehydrogenase 0.007
Aldehyde reductase 0.007
AKR1B1 0.006
aldo-keto reductase 0.006
AKR1A1 0.003
NADPH 0.002
NADP+ 0.001
dihydrodiol dehydrogenase 0.001
chlordecone reductase 0.001
AFAR 0.001
ARI 0.001
NADPH-dependent carbonyl reductase 0.001
AKR1B1 protein 0.001
carbonyl reductase 0.001
aldehyde reductase I 0.001
SMIT 0.001
more...
Disease
diabetic cataract 0.006
diabetic neuropathy 0.004
diabetes 0.001
hyperglycemia 0.001
diabetic retinopathy 0.001
cataract 0.001
galactosemia 0.001
retinopathy 0.000
lens opacity 0.000
neuropathy 0.000
diabetic nephropathy 0.000
Diabetic neuropathy 0.000
Cardiac autonomic neuropathy 0.000
Diabetic polyneuropathy 0.000
Osmotic nephrosis 0.000
Sensorimotor polyneuropathy 0.000
autonomic neuropathy 0.000
Armanni-Ebstein lesion 0.000
diabetic hyperglycemia 0.000
IDD 0.000
more...
Symptom
strangury 0.000
Blanching 0.000
Spots 0.000
inanition 0.000
presyncope 0.000
urethral discharge 0.000
polyuria 0.000
Halo 0.000
hyperesthesia 0.000
Anoxia 0.000
ketonuria 0.000
pain 0.000
numbness 0.000
cachexia 0.000
muscle cramps 0.000
DNA marker 0.000
polydipsia 0.000
eds 0.000
Hudson 0.000
functional recovery 0.000
more...
Drug
Ponalrestat 0.012
Epalrestat 0.011
Fidarestat 0.007
Fidarestat 0.007
Alrestatin 0.004
Ranirestat 0.002
Zenarestat 0.002
Minalrestat 0.002
Alond 0.001
Lidorestat 0.000
Alredase 0.000
C13H19NO2 0.000
Myo-Inositol 0.000
NADH 0.000
Hexitol 0.000
Galactose 0.000
Bendazac 0.000
Lodoxamide tromethamine 0.000
Timiperone 0.000
Clinoril 0.000
more...
Enzyme
aldose reductase 0.999
aldehyde reductase 0.150
aldehyde reductase 0.139
aldehyde reductase 0.139
CPR 0.014
sorbitol dehydrogenase 0.013
alcohol dehydrogenase 0.008
mannitol dehydrogenase 0.007
carbonyl reductase 0.001
dihydrodiol dehydrogenase 0.001
prostaglandin F synthase 0.001
xylitol dehydrogenase 0.000
2,5-diketo-D-gluconate reductase 0.000
xylitol dehydrogenase 0.000
EC 1.1.99.22 0.000
3(17)alpha-hydroxysteroid dehydrogenase 0.000
GRase 0.000
D-xylonate dehydratase 0.000
ketohexokinase 0.000
dulcitol dehydrogenase 0.000
more...
Compound
Sorbinil 0.032
Tolrestat 0.009
Zopolrestat 0.005
Sorbitol 0.003
NADPH 0.002
NADPH 0.002
2-benzyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole 0.001
NADP 0.001
glucose 0.001
aldehyde 0.001
aldehyde 0.001
C13H12O5 0.001
C13H12O5 0.001
C13H12O5 0.001
Byakangelicin 0.001
C13H12O5 0.001
C13H12O5 0.001
C13H12O5 0.001
C13H12O5 0.001
C13H12O5 0.001
more...