Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:1.1.1.1 (alcohol dehydrogenase)
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Human Gene/Protein
EF-hand calcium binding domain 5 11.7
aldehyde reductase 11.7
ISG12 protein 11.7
ADH5 protein 11.7
Synaptotagmin XV 11.7
ADH 11.7
alcohol dehydrogenase 11.7
eye lens structural protein 11.7
class II alcohol dehydrogenase 11.7
class I alcohol dehydrogenase 11.5
ADH-5 11.3
gastric alcohol dehydrogenase 11.3
ADH1A 11.2
ADH7 11.1
ADH4 11.1
ADH6 11.1
Aldehyde reductase 11.0
ADH3 11.0
ADH5 10.9
ABAD 10.9
ADH2 10.8
alcohol dehydrogenase 7 10.7
Vasopressin-neurophysin 10.7
SERHL2 10.7
KIAA0822 10.7
isochorismatase domain containing 1 10.7
SCALD 10.7
microtubule-associated protein, RP/EB family, member 1 10.7
glutathione-dependent formaldehyde dehydrogenase 10.6
ADH1B 10.5
ADH1 10.4
AKR7A4 10.4
AKR1A1 10.3
Alcohol dehydrogenase 10.2
Alcohol dehydrogenase 3 10.2
Alcohol dehydrogenase 1C 10.2
stomach aldehyde dehydrogenase 10.2
LC27 10.2
ALDR1 10.2
hydroxysteroid dehydrogenase like 2 10.2
aldehyde dehydrogenase I 10.2
acetaldehyde dehydrogenase 10.1
chlordecone reductase 10.0
AFAR 9.9
GSTA5 9.8
ATP synthase gamma chain 9.7
ADHFE1 9.7
matrilin 2 9.7
MRP-S9 9.7
HNRPH1 9.7
AAD14 9.7
polypeptide N-acetylgalactosaminyltransferase 7 9.7
MTIF2 9.7
PDC2 9.5
MLLT2 9.4
ALR2 9.4
leukotriene B4 omega-hydroxylase 9.4
inosine monophosphate dehydrogenase type II 9.4
aldehyde dehydrogenase 9.3
AKR7A2 9.3
alcohol dehydrogenase 1 9.2
CPAD 9.2
GSNOR 9.2
DSN1 9.2
Glutamic dehydrogenase 9.2
ZNF44 9.2
short-chain dehydrogenase/reductase 1 9.2
NADPH-dependent carbonyl reductase 9.2
RNA-binding motif 3 9.2
acetaldehyde dehydrogenase 2 9.1
ALDH2 9.0
retinol dehydrogenase 9.0
toll interacting protein 8.9
ALDC 8.9
interferon gamma receptor 2 8.9
FAM96A 8.9
ALR mRNA 8.9
glutathione S-transferase mu 5 8.9
L-threonine dehydrogenase 8.8
CYP4Z2P 8.7
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Disease
ADH 11.7
ADH2*3 11.3
ADH3*1 11.0
UDH 10.9
Idiopathic diabetes insipidus 10.7
ADH3*2 10.0
Neonatal hyponatremia 9.7
Acute alcoholic intoxication 9.7
ADH decreased 9.2
SIADH 9.1
HYD2 8.7
psilosis 8.7
ACS II 8.6
galactophoritis 8.4
alcohol flush reaction 8.4
alcoholic gastritis 8.3
LCIS 8.1
Chronic hyponatremia 8.0
Tonsillar herniation 7.7
NALD 7.7
acetonemia 7.4
CND 7.4
FDH 7.3
Tick-borne disease 7.2
Water intoxication 7.2
antidiuresis 7.2
Acute decompensated heart failure 7.2
acute alcohol intoxication 7.1
Congenital nephrogenic diabetes insipidus 7.1
Psychogenic polydipsia 7.1
AD11 7.0
lobular carcinoma in situ 7.0
Acute hyponatremia 6.9
FBH1 6.9
Immature teratoma 6.8
Central diabetes insipidus 6.8
FH3 6.7
alcoholic pancreatitis 6.7
DIA 6.6
diabetes insipidus 6.6
hypo-osmolality 6.6
Aeromonas infections 6.5
DRD 6.4
Alcoholic liver disease 6.3
carcinoma of the ureter 6.3
PPR1 6.3
PDC 6.3
arcus senilis 6.3
MD1 6.2
acute alcoholism 6.2
alcoholic cardiomyopathy 6.2
hypernatremia 6.2
Substance dependence 6.0
alcohol effect 5.9
Gerhardt 5.9
hypothalamic disorder 5.7
hypoaldosteronism 5.7
alcohol impairment 5.6
LAP 5.6
nephrogenic diabetes insipidus 5.6
extrapyramidal disorder 5.6
alcohol withdrawal syndrome 5.5
disorders of calcium metabolism 5.5
alcoholic cirrhosis 5.5
drunk 5.5
Inhalant abuse 5.5
cellular schwannoma 5.5
alcoholism 5.5
Central pontine myelinolysis 5.5
TD1 5.4
hyperosmolality 5.4
Lymphocytic hypophysitis 5.3
ductal carcinoma in situ 5.3
Paget's disease of the nipple 5.3
CTPA 5.2
Medulla 5.2
Bartter's syndrome 5.2
alcoholic hepatitis 5.2
alcoholic ketoacidosis 5.2
macromastia 5.1
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Symptom
hangover 7.2
adipsia 6.5
nocturnal polyuria 6.1
Hangover 6.1
polyuria 5.7
polydipsia 5.5
astasia 4.8
flushing 4.6
bedwetting 4.5
thirsty 4.4
Anoxia 4.2
aphagia 4.1
loss of balance 3.9
ACHE 3.9
enuresis 3.6
ketonuria 3.6
lassitude 3.6
presyncope 3.5
neck stiffness 3.5
autodigestion 3.4
Hudson 3.3
Spots 2.9
eds 2.7
Decreased activity 2.7
sinus pressure 2.7
nipple discharge 2.6
excessive sweating 2.6
oliguria 2.5
leg edema 2.3
forgetfulness 2.3
clonus 2.2
consciousness disturbance 2.1
muscle cramps 1.9
acidity 1.9
dysesthesia 1.9
dizziness 1.8
emaciation 1.7
productive cough 1.6
hypoproteinemia 1.6
nausea 1.5
hypertonia 1.5
tonic-clonic seizure 1.4
chills 1.3
lethargy 1.3
vomiting 1.2
starvation 1.1
hypothermia 1.1
menopausal symptoms 1.1
ophthalmoplegia 1.0
hypocapnia 1.0
neuralgia 1.0
memory loss 0.9
anorexia 0.8
hypercapnia 0.8
anesthesia 0.8
agitation 0.8
twitching 0.7
apathy 0.7
blurred vision 0.7
chorea 0.7
sleepiness 0.7
Ill 0.6
dysuria 0.5
spasm 0.5
masculinization 0.4
seizures 0.4
exhaustion 0.3
hypotonia 0.2
tremor 0.2
syncope 0.2
analgesia 0.1
spasticity 0.1
stigma 0.0
constipation 0.0
epigastric pain -0.0
discomfort -0.0
vertigo -0.1
cerebellar ataxia -0.1
discomfort -0.1
cyanosis -0.1
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Drug
N-Heptylformamide 11.7
4-Iodopyrazole 11.7
1-Aminocyclopropanecarboxylic Acid 11.7
Liver hydrolysate 10.7
Telavancin hydrochloride 10.4
Antizol 10.2
2-Butanol 9.9
Lasofoxifene tartrate 9.7
Etacrynic acid 9.7
1,4-Butanediol 9.7
Minalrestat 9.2
Oxilorphan 9.2
Lumiliximab 9.2
Apaziquone 8.9
Succinobucol 8.7
Ponalrestat 8.7
Bavituximab 8.6
Focalin 8.6
Timiperone 8.6
Enzastaurin hydrochloride 8.4
Aliskiren fumarate 8.2
Ches 8.0
Dapoxetine hydrochloride 8.0
Alclofenac 8.0
Indisulam 7.9
Fidarestat 7.9
Fidarestat 7.9
Octapressin 7.8
Bazedoxifene acetate 7.8
Alrestatin 7.7
Fenobam 7.7
Teduglutide 7.6
Indiplon 7.6
1,3-Butanediol 7.5
Ziprasidone hydrochloride 7.4
Metreleptin 7.4
Cibacron Blue 7.2
Peginterferon alfa-2b 7.2
Peginterferon alfa-2b 7.2
NADH 7.2
Micafungin sodium 7.2
2-Methoxyethanol 7.1
Decane 7.1
Ethanol 7.1
Genasense 6.9
Carboxyatractyloside 6.9
Duloxetine hydrochloride 6.8
Bicine 6.7
Retapamulin 6.7
Pixantrone 6.7
Escitalopram oxalate 6.7
Histalog 6.7
Pemetrexed disodium 6.6
all-trans-retinol 6.6
Tolvaptan 6.6
Lonafarnib 6.5
Methyl aminolevulinate 6.5
Histidinol 6.5
Quinate 6.5
Ixabepilone 6.4
Travoprost 6.4
Somatropin 6.2
Pegasys 6.2
Epalrestat 6.1
Silodosin 6.0
Tykerb 6.0
Certolizumab pegol 5.9
Red ginseng 5.9
Adefovir dipivoxil 5.8
Pentane 5.8
Amlodipine besylate 5.8
Rosuvastatin calcium 5.8
Pitressin 5.7
Tipifarnib 5.6
Sunitinib malate 5.6
Narcan 5.5
Tritiated water 5.5
Aprepitant 5.5
Alefacept 5.5
TMX 5.5
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Enzyme
hexadecanol dehydrogenase 11.7
EC 1.1.1.161 11.7
alcohol dehydrogenase 11.7
ADH 11.7
aldehyde reductase 11.7
aldehyde reductase 11.7
aldehyde reductase 11.7
ADH3 11.1
long-chain alcohol dehydrogenase 10.9
mycothiol-dependent formaldehyde dehydrogenase 10.9
indanol dehydrogenase 10.7
isopropanol dehydrogenase 10.7
3-hydroxybutyryl-CoA dehydratase 10.7
secondary alcohol oxidase 10.7
allyl-alcohol dehydrogenase 10.7
formaldehyde dismutase 10.4
octanol dehydrogenase 10.0
fatty alcohol oxidase 9.9
FAEES 9.7
GRase 9.7
2,5-diketo-D-gluconate reductase 9.7
pyruvate decarboxylase 9.7
lysoplasmalogenase 9.6
D-xylonate dehydratase 9.6
aryl-alcohol dehydrogenase 9.6
3-hydroxybutyryl-CoA dehydrogenase 9.5
xylonolactonase 9.4
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 9.4
phenylpyruvate decarboxylase 9.4
SADH 9.4
acetoacetate decarboxylase 9.4
octopine dehydrogenase 9.4
aldehyde dehydrogenase 9.3
aldehyde dehydrogenase 9.3
aldehyde dehydrogenase 9.3
oleate hydratase 9.2
enoate reductase 9.2
L-BDH 9.2
EC 1.1.1.56 9.2
3(17)alpha-hydroxysteroid dehydrogenase 9.2
PhnN 9.2
benzyl alcohol dehydrogenase 9.1
aldehyde dehydrogenase 9.1
2,3-butanediol dehydrogenase 9.1
aldose reductase 9.0
aldehyde dehydrogenase 8.9
hydroxyacid-oxoacid transhydrogenase 8.9
quinate dehydrogenase 8.9
geraniol dehydrogenase 8.9
ribonuclease alpha 8.9
2-oxoaldehyde dehydrogenase 8.9
2-oxoaldehyde dehydrogenase 8.9
formaldehyde dehydrogenase 8.9
methylglyoxal reductase 8.8
acetolactate decarboxylase 8.8
4-hydroxybutyrate dehydrogenase 8.7
quinate dehydrogenase 8.7
strombine dehydrogenase 8.7
retinal oxidase 8.7
lactaldehyde dehydrogenase 8.7
ALDH 8.6
EC 1.1.1.219 8.6
macrocin O-methyltransferase 8.6
CobQ 8.6
PVA oxidase 8.6
prostaglandin F synthase 8.6
lactaldehyde dehydrogenase 8.5
phenylacetaldehyde dehydrogenase 8.5
arogenate dehydrogenase 8.5
malate thiokinase 8.4
acetone carboxylase 8.4
CPR 8.4
MDH 8.4
phosphoenolpyruvate-protein phosphotransferase 8.3
2-alkenal reductase 8.3
D-sorbitol dehydrogenase 8.3
enzyme X 8.2
acetate kinase 8.2
triokinase 8.2
dihydrodiol dehydrogenase 8.1
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Compound
4-oxooctanoic acid 11.7
heptylformamide 11.7
2-chloroacrylic acid 11.7
3-hexadecanone 11.7
alcohol dehydrogenase 11.7
4-methoxy-1-naphthaldehyde 11.3
4-methoxy-1-naphthaldehyde 10.7
1,3-difluoroacetone 10.7
5-dodecanol 10.7
2,2,2-trifluoro-1-phenylethanol 10.7
2-benzyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole 10.7
4-Methylpyrazole 10.7
p-Nitrobenzaldehyde 10.4
2-chloroethyl methanesulfonate 10.4
benzylformamide 10.3
4-(diethylamino)benzaldehyde 10.2
3-bromopropanoic acid 10.2
2-Nitrobenzyl alcohol 10.2
1,3-difluoro-2-propanol 10.2
(S)-1-Phenylethanol 9.7
cyclohexylformamide 9.7
2-hydroxycyclohexanone 9.7
Isoursodeoxycholic acid 9.7
Methylene green 9.7
Etacrynic acid 9.7
C9H10O3 9.7
C7H7NO3 9.7
2,2-dichloroethanol 9.6
1H-indole-3-carbaldehyde 9.5
12-hydroxydodecanoic acid 9.5
2-hydroxycyclohexanone 9.4
C26H54 9.4
C26H54 9.4
C26H54 9.4
Methylene green 9.4
C26H54 9.4
C26H54 9.4
C26H54 9.4
2-hydroxycyclohexanone 9.4
C26H54 9.4
C26H54 9.4
2-tetradecanol 9.4
C15H22O3 9.4
C26H54 9.4
C26H54 9.4
3-iodopyridine 9.4
Eutypine 9.4
2-hexadecanol 9.4
Adipic acid dihydrazide 9.4
isodeoxycholic acid 9.4
C26H54 9.4
Moxifloxacin hydrochloride 9.4
C26H54 9.4
2-nonenoic acid 9.4
methoxyacetaldehyde 9.3
2,3-dichloro-1-propene 9.2
9-cis-Retinal 9.2
4-methyl-1-pentanol 9.2
3-methyl-1,5-pentanediol 9.2
4-hexanolide 9.2
1,2,4-butanetriol 9.1
2-phenyl-1-propanol 9.0
2-phenylpropanal 9.0
1,3-dichloroacetone 9.0
1-phenyl-2-propanol 9.0
1,3-dichloroacetone 9.0
C10H14O 8.9
Acetone cyanohydrin 8.9
ethyl 4-chloro-3-oxobutanoate 8.9
Gulonate 8.9
allyl formate 8.9
4-phenyl-2-butanol 8.8
AR 1 8.7
undecanedioic acid 8.7
16-hydroxyhexadecanoic acid 8.7
3-pyrrolidinone 8.7
acetaldehyde 8.7
3-methoxybenzaldehyde 8.7
3-methoxybenzaldehyde 8.7
NPOH 8.7
more...