Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: DrugBank:EXPT03052 (THF)
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Human Gene/Protein
Serine hydroxymethyltransferase 0.004
serine hydroxymethyltransferase 0.002
methionine synthase 0.001
dihydrofolate reductase 0.001
10-formyltetrahydrofolate dehydrogenase 0.001
NMR 0.001
Dihydrofolate reductase 0.001
thymidylate synthase 0.001
methylenetetrahydrofolate dehydrogenase 0.001
folylpolyglutamate synthetase 0.001
cytosolic serine hydroxymethyltransferase 0.001
reductase 0.001
C1-tetrahydrofolate synthase 0.001
thymidylate synthetase 0.001
dimethylglycine dehydrogenase 0.001
DIPP 0.000
tetrahydrofolate dehydrogenase/cyclohydrolase 0.000
formyltetrahydrofolate synthetase 0.000
H-protein 0.000
dimeric 0.000
formyltetrahydrofolate dehydrogenase 0.000
CHC 0.000
MTHFD2L 0.000
Formiminotransferase-cyclodeaminase 0.000
GAR transformylase 0.000
SHMT 0.000
folylpoly-gamma-glutamate synthetase 0.000
EPR 0.000
methionine synthase reductase 0.000
sarcosine dehydrogenase 0.000
aminomethyltransferase 0.000
reduced folate carrier 0.000
folate-binding protein 0.000
GRL 0.000
glycine decarboxylase 0.000
mu4 0.000
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 0.000
SHMT2 0.000
B12 0.000
MTHFR 0.000
Cytosolic serine hydroxymethyltransferase 0.000
Glycine synthase 0.000
TMS 0.000
ALDH1L2 0.000
DHFR 0.000
NADP+ 0.000
NHC 0.000
glycinamide ribonucleotide formyltransferase 0.000
dihydrofolate reductase-like 1 0.000
Type II adenylyl cyclase 0.000
AMT protein 0.000
factor V Leiden 0.000
COT 0.000
SHMT1 0.000
ACN 0.000
NADP 0.000
C1orf69 0.000
Aminomethyltransferase 0.000
SAF-2 0.000
ALDH1L1 0.000
C-C 0.000
NADPH 0.000
NaN 0.000
methylenetetrahydrofolate dehydrogenase 1 0.000
mitochondrial serine hydroxymethyltransferase 0.000
Formyltetrahydrofolate synthetase 0.000
indolethylamine N-methyltransferase 0.000
MTHFD1 0.000
SLC25A32 0.000
cystathionine beta-synthase 0.000
dihydrofolate reductase-like protein 1 0.000
cytoplasmic serine hydroxymethyltransferase 0.000
purH 0.000
PF6 0.000
FDH 0.000
Glycinamide ribonucleotide formyltransferase 0.000
CMH2 0.000
hormone receptor 0.000
Reduced folate carrier 0.000
SRP40 0.000
more...
Disease
folate deficiency 0.000
hyperhomocysteinemia 0.000
NHC 0.000
methionine synthase deficiency 0.000
LDA 0.000
Gurrieri syndrome 0.000
R-binder deficiency 0.000
CMH2 0.000
Factor II mutation 0.000
megaloblastic anemia 0.000
homocystinuria 0.000
FH3 0.000
NF2 0.000
vitamin B12 deficiency 0.000
hydroxyprolinemia 0.000
transcobalamin II deficiency 0.000
FDH 0.000
ABPE 0.000
CHN 0.000
vitamin B deficiency 0.000
DHPR deficiency 0.000
HPA1 0.000
CBS deficiency 0.000
Condensation 0.000
folate deficiency anemia 0.000
Thrombophilia 0.000
NNH 0.000
Primary Sjogren's syndrome 0.000
cblF 0.000
idiopathic dilated cardiomyopathy 0.000
PPCD 0.000
TEM 0.000
TEM 0.000
PCH2 0.000
hyperglycinemia 0.000
ICT 0.000
OOCH 0.000
DMAC 0.000
CEM 0.000
Subacute combined degeneration 0.000
MGA3 0.000
DMAT 0.000
homocystinemia 0.000
TBS 0.000
NBS 0.000
Androgen excess 0.000
NDI 0.000
cancer 0.000
Steroids 0.000
CIE 0.000
retinopathy of prematurity 0.000
pernicious anemia 0.000
CHR 0.000
Protein S deficiency 0.000
MAS 0.000
retinal vein thrombosis 0.000
FADS 0.000
basal ganglia disease 0.000
PAA 0.000
FHF 0.000
dehydration 0.000
SEM 0.000
DBM 0.000
11 beta-hydroxylase deficiency 0.000
hyperprolinemia 0.000
Retinal vein occlusion 0.000
MCD 0.000
Salmonella bacteremia 0.000
Horner's syndrome 0.000
choline deficiency 0.000
PCL 0.000
Oral ulcers 0.000
leukemia 0.000
tumor 0.000
antiphospholipid syndrome 0.000
GCE 0.000
hypoaldosteronism 0.000
orotic aciduria 0.000
PCP 0.000
Multiple chemical sensitivity 0.000
more...
Symptom
acidity 0.000
iridodonesis 0.000
skin irritant 0.000
rectal pain 0.000
Halo 0.000
labored breathing 0.000
Decreased activity 0.000
forgetfulness 0.000
right upper quadrant pain 0.000
paraparesis 0.000
CSR 0.000
general problem 0.000
pallor 0.000
abnormal gait 0.000
incoordination 0.000
leg pain 0.000
blurred vision 0.000
tense 0.000
polydipsia 0.000
collapse 0.000
lethargy 0.000
nausea 0.000
seizures 0.000
sore throat 0.000
starvation 0.000
tremor 0.000
HSA 0.000
agitation 0.000
ophthalmoplegia 0.000
exhaustion 0.000
anorexia 0.000
vomiting 0.000
cyanosis 0.000
dysarthria 0.000
ataxia 0.000
hemiplegia 0.000
headache 0.000
diarrhea 0.000
shortness of breath 0.000
hunger 0.000
fatigue 0.000
weakness 0.000
hemoptysis 0.000
flushing 0.000
spasm 0.000
splenomegaly 0.000
constipation 0.000
insomnia 0.000
thinning 0.000
pain 0.000
chest pain 0.000
hypothermia 0.000
dyspnea 0.000
anesthesia 0.000
Drug
THF 1.000
Leucovorin 0.000
TMS 0.000
CrCl3 0.000
pyridoxal phosphate 0.000
Pratosartan 0.000
BH4 0.000
Cobalamin 0.000
Avapro 0.000
2,4,6-Trinitrophenol 0.000
DMAP 0.000
InCl3 0.000
Padimate O 0.000
Vitamin B12 0.000
7,8-Dihydroneopterin 0.000
FAD 0.000
Norvaline 0.000
ZnCl2 0.000
ZnCl2 0.000
2-Methoxyethanol 0.000
Aldomet 0.000
TMC114 0.000
Fenbufen 0.000
PPA 0.000
Allegra 0.000
Allegra 0.000
NH3 0.000
ZnI2 0.000
RPH 0.000
L-Ser 0.000
NaI 0.000
NaI 0.000
NaI 0.000
NaI 0.000
Darunavir 0.000
FeCl3 0.000
CEC 0.000
TMX 0.000
Hakka 0.000
Alimta 0.000
Dihydro 0.000
Flavin 0.000
Compound 19 0.000
Ovulen 0.000
CoCl2 0.000
CoCl2 0.000
PCP 0.000
NADH 0.000
ascorbate 0.000
Compound 9 0.000
Compound 18 0.000
TPV 0.000
FLP 0.000
Compound 15 0.000
Vitamin B 0.000
TES 0.000
Pyridoxal phosphate 0.000
Lead acetate 0.000
Methyldopa 0.000
Trimethoprim-sulfamethoxazole 0.000
Asn 0.000
lysine 0.000
Riboflavin 0.000
CSI 0.000
Poloxamer 188 0.000
Estriol 0.000
Alteplase 0.000
-deoxyadenosine 0.000
Gliclazide 0.000
Sodium alginate 0.000
Alteplase 0.000
CDX 0.000
Pyridoxal 0.000
Alteplase 0.000
Furan 0.000
Silica gel 0.000
Sandostatin 0.000
Sandostatin 0.000
CPO 0.000
Fipronil 0.000
more...
Enzyme
serine hydroxymethyltransferase 0.002
10-formyltetrahydrofolate dehydrogenase 0.002
methionine synthase 0.002
thymidylate synthase 0.001
dihydrofolate reductase 0.001
methionine synthase 0.001
folylpolyglutamate synthetase 0.001
formyltetrahydrofolate synthetase 0.001
T-protein 0.001
cyclohydrolase 0.001
dimethylglycine dehydrogenase 0.001
DIPP 0.000
glycinamide ribonucleotide transformylase 0.000
methylenetetrahydrofolate dehydrogenase 0.000
dihydrofolate synthetase 0.000
dimethylglycine oxidase 0.000
glutamate formiminotransferase 0.000
EC 4.3.1.4 0.000
methionine synthase reductase 0.000
sarcosine dehydrogenase 0.000
conjugase 0.000
homocysteine methyltransferase 0.000
AICAR transformylase 0.000
deoxycytidylate methyltransferase 0.000
methylenetetrahydrofolate dehydrogenase 0.000
glycine decarboxylase 0.000
ketopantoate hydroxymethyltransferase 0.000
MetE 0.000
dihydropteroate synthase 0.000
11beta-hydroxysteroid dehydrogenase 0.000
NADPH peroxidase 0.000
methanethiol oxidase 0.000
dihydroneopterin aldolase 0.000
methylenetetrahydrofolate reductase 0.000
cystathionine beta-synthase 0.000
TPP 0.000
HPPK 0.000
dCMP hydroxymethylase 0.000
IMP cyclohydrolase 0.000
sarcosine oxidase 0.000
TPP 0.000
methionyl-tRNA formyltransferase 0.000
methylenetetrahydrofolate reductase 0.000
GAR 0.000
oxalyl-CoA synthetase 0.000
N5,N10-methenyltetrahydromethanopterin cyclohydrolase 0.000
phospholipid methyltransferase 0.000
formaldehyde dismutase 0.000
HIV-1 protease 0.000
threonine aldolase 0.000
erythritol kinase 0.000
PurK 0.000
formyl-CoA transferase 0.000
dichloromethane dehalogenase 0.000
5,10-methenyltetrahydrofolate synthetase 0.000
alkylglycerol monooxygenase 0.000
demethylase 0.000
GTP cyclohydrolase I 0.000
formate dehydrogenase 0.000
formate dehydrogenase 0.000
glycine dehydrogenase 0.000
glycine dehydrogenase 0.000
PurE 0.000
cystathionine gamma-synthase 0.000
formate dehydrogenase 0.000
methylmalonyl-CoA mutase 0.000
methionine adenosyltransferase 0.000
phosphoglycerate dehydrogenase 0.000
CO dehydrogenase 0.000
protocatechuate 4,5-dioxygenase 0.000
phosphoethanolamine N-methyltransferase 0.000
betaine-homocysteine methyltransferase 0.000
HSD 0.000
glycine dehydrogenase 0.000
staphopain 0.000
homoprotocatechuate 2,3-dioxygenase 0.000
hydrogenase 0.000
hydrogenase 0.000
aureolysin 0.000
SAICAR synthetase 0.000
more...
Compound
THF 0.771
THF 0.415
10-formyltetrahydrofolate 0.008
dihydrofolate 0.006
CH3-THF 0.005
5-formyltetrahydrofolate 0.003
5,10-methenyltetrahydrofolate 0.002
5,10-methylene-THF 0.002
toluene 0.002
TMEDA 0.001
2,6-diisopropylphenyl 0.001
homocysteine 0.001
dUMP 0.001
PGA 0.001
DMF 0.001
HPT 0.000
alpha-THF 0.000
pyridine 0.000
dichloromethane 0.000
1,2-dimethoxyethane 0.000
10-formyldihydrofolate 0.000
mesityl 0.000
C4H8O 0.000
TMP 0.000
C4H8O 0.000
C4H8O 0.000
C4H8O 0.000
C4H8O 0.000
DMSO 0.000
C4H8O 0.000
C4H8O 0.000
H4MPT 0.000
4-cyclohexene-1,2-diol 0.000
folinic acid 0.000
N,N'-diisopropylcarbodiimide 0.000
pteridine 0.000
HVA 0.000
C4H8O 0.000
C6H2 0.000
1-hexene 0.000
NADP 0.000
1,4-dioxane 0.000
tribromosilane 0.000
N-methyl-N-phenylacrylamide 0.000
C8H7Br 0.000
2-methyl-2-cyclohexen-1-ol 0.000
7-Methylpterin 0.000
C30H28N4O2 0.000
Benzalaniline 0.000
C26H28O2 0.000
C17H14N4 0.000
1-bromo-4-tert-butylbenzene 0.000
ethyl 2,2-dimethyl-3-oxobutanoate 0.000
1-naphthylsilane 0.000
C30H28N4O2 0.000
2,6-dibenzylphenol 0.000
Dimethylglycine 0.000
hexane 0.000
hydrogen 0.000
methionine 0.000
PTGA 0.000
benzene 0.000
BF4 0.000
BF4 0.000
BF4 0.000
salt 0.000
acetonitrile 0.000
2,5-dimethyltetrahydrofuran 0.000
5,10-Methylenetetrahydrofolate 0.000
1-iodobutane 0.000
alpha-cortol 0.000
Pteroic acid 0.000
heptanenitrile 0.000
C9H10N2O4 0.000
C9H14 0.000
C9H10N2O4 0.000
C6H15N3 0.000
C4H8S2 0.000
C9H10N2O4 0.000
C9H10N2O4 0.000
more...