Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: DrugBank:EXPT03052 (THF)
8,150 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein NMR 1136 Sep 608 reductase 412 dimeric 270 Mol 233 dihydrofolate reductase 232 thymidylate synthase 158 EPR 150 NADPH 130 B12 105 methionine synthase 104 C-C 94 serine hydroxymethyltransferase 88 CO2 88 ATP 84 fused 76 NADP 75 thymidylate synthetase 71 cage 67 Serine hydroxymethyltransferase 61 hormone receptor 58 ACS 54 methyltransferase 54 NADP+ 53 Dihydrofolate reductase 53 folylpolyglutamate synthetase 50 TEM 49 TMS 49 prothrombin 44 NHC 44 TOF 43 MTHFR 40 NIR 40 methylenetetrahydrofolate dehydrogenase 39 factor V Leiden 39 ESI 38 dilute 38 Boc 37 CHC 35 oxidoreductase 35 FAD 34 Poly 33 NAD 33 tRNA 32 PF6 32 AFM 32 DHFR 31 MP2 30 NADH 29 THP 29 COD 28 ACN 28 ESR 26 glycine decarboxylase 25 reduced folate carrier 25 polypeptide 24 DSC 24 mer 24 TGA 24 methylenetetrahydrofolate reductase 24 NaN 23 10-formyltetrahydrofolate dehydrogenase 23 TMP 23 C18 22 GTP 22 PDI 22 PEG 22 TPP 22 gem 20 PNP 20 protein C 20 H-protein 20 Pseudomonas 20 SDS 20 hGH 20 PEO 20 methionine synthase reductase 19 cystathionine beta-synthase 19 MTX 18 ADP 18 more...

Disease cancer 271 tumor 155 folate deficiency 66 hyperhomocysteinemia 65 leukemia 57 TEM 49 TEM 49 SEM 45 NHC 44 colorectal cancer 35 hypertension 35 LDA 34 dehydration 32 cardiovascular disease 30 NF2 28 HIV 28 breast cancer 28 MCF 26 megaloblastic anemia 26 stroke 26 carcinoma 26 adenocarcinoma 25 Steroids 24 homocystinuria 21 depression 20 SDS 20 diabetes 20 cold 20 CEM 20 carcinogenesis 19 colon cancer 18 vascular disease 18 mole 18 fits 18 vitamin B12 deficiency 18 Mycobacterium 18 mole 18 idiopathic dilated cardiomyopathy 17 obesity 17 neuroblastoma 16 anemia 16 Evans 16 MAS 15 malaria 15 atherosclerosis 15 tuberculosis 15 hepatocellular carcinoma 14 squamous cell carcinoma 14 PCP 14 GSH 14 PCL 13 acute lymphoblastic leukemia 13 deep vein thrombosis 13 solid tumor 13 Alzheimer's disease 13 CHN 12 malnutrition 12 Condensation 12 antiphospholipid syndrome 12 retinopathy of prematurity 12 NBS 11 lung cancer 11 Cushing's syndrome 11 coronary artery disease 10 ICT 10 gastric cancer 10 CIE 10 PAA 10 Dissociation 9 tumor growth 9 FDH 9 immunodeficiency 8 chronic myeloid leukemia 8 AIDS 8 pernicious anemia 8 lymphoblastic leukemia 8 dementia 8 systemic lupus erythematosus 8 infectious diseases 8 Thrombophilia 8 more...

Symptom acidity 62 seizures 10 pain 7 diarrhea 6 collapse 6 headache 6 vomiting 5 nausea 5 starvation 5 fatigue 5 weakness 4 tremor 4 agitation 3 ataxia 3 paraparesis 3 anorexia 3 exhaustion 3 anesthesia 2 Halo 2 lethargy 2 pallor 2 splenomegaly 1 constipation 1 sore throat 1 shortness of breath 1 Decreased activity 1 cyanosis 1 abnormal gait 1 incoordination 1 dysarthria 1 ophthalmoplegia 1 HSA 1 hemoptysis 1 thinning 1 right upper quadrant pain 1 dyspnea 1 tense 1 general problem 1 blurred vision 1 leg pain 1 skin irritant 1 labored breathing 1 forgetfulness 1 iridodonesis 1 spasm 1 rectal pain 1 flushing 1 hunger 1 insomnia 1 polydipsia 1 hemiplegia 1 chest pain 1 hypothermia 1 CSR 1

Drug THF 8150 TMS 49 pyridoxal phosphate 39 lysine 34 FAD 34 NADH 28 ascorbate 28 BH4 28 Leucovorin 23 NH3 22 DMAP 20 Vitamin B12 19 Asn 15 ZnCl2 13 ZnCl2 13 ZnO 12 Cobalamin 11 Gel 11 PCP 11 CrCl3 10 NaI 10 NaI 10 NaI 10 NaI 10 TiO2 9 FeCl3 8 CEC 7 CoCl2 6 CoCl2 6 EE2 6 PPA 6 ENT 6 PCB 5 InCl3 5 Vitamin B 5 FLP 5 SiO2 5 CAM 5 MOF 5 Ethanol 5 -deoxyadenosine 5 HCH 4 CSF 4 Dermatol 4 Monit 4 Dihydro 4 lactose 4 MAP 4 IL-2 4 nitroglycerin 3 Riboflavin 3 CaCl2 3 CaCl2 3 CaCl2 3 Flavin 3 ETA 3 Alanine 3 TES 3 L-Ser 3 Dial 3 Bifidobacterium 2 ROS 2 Nitric Oxide 2 Fragment 2 Trimethoprim-sulfamethoxazole 2 vitamin E 2 PMEA 2 CSI 2 Lactose 2 Cardiovasc 2 Fluorescein 2 Leaf 2 citric acid 2 Biopolymers 2 Darunavir 2 DPA 2 L-tyrosine 2 Compound 9 2 Alimta 1 TTC 1 more...

Enzyme dihydrofolate reductase 260 thymidylate synthase 207 methionine synthase 107 serine hydroxymethyltransferase 105 methionine synthase 90 ACS 56 folylpolyglutamate synthetase 52 cyclohydrolase 50 formyltetrahydrofolate synthetase 32 methylenetetrahydrofolate reductase 31 10-formyltetrahydrofolate dehydrogenase 30 T-protein 29 APC 28 demethylase 28 methylenetetrahydrofolate reductase 26 glycine decarboxylase 26 11beta-hydroxysteroid dehydrogenase 25 glycinamide ribonucleotide transformylase 23 complex I 23 methylenetetrahydrofolate dehydrogenase 22 TPP 22 TPP 22 ERK 21 conjugase 20 HIV-1 protease 20 cystathionine beta-synthase 19 aldehyde dehydrogenase 18 methionine synthase reductase 18 lipase 17 HSD 17 hydrogenase 16 focal adhesion kinase 16 hydrogenase 16 dihydropteroate synthase 16 homocysteine methyltransferase 15 DIPP 15 aldehyde dehydrogenase 15 aldehyde dehydrogenase 15 aldehyde dehydrogenase 15 aldehyde dehydrogenase 15 monoamine oxidase 13 dimethylglycine dehydrogenase 13 dihydrofolate synthetase 12 renin 12 formate dehydrogenase 11 formate dehydrogenase 11 formate dehydrogenase 11 ACE 11 methylenetetrahydrofolate dehydrogenase 11 PCP 11 ATPase 9 sarcosine dehydrogenase 9 GTP cyclohydrolase I 9 aldolase 9 AICAR transformylase 8 subtilisin 8 methionine adenosyltransferase 8 DNA polymerase 8 peroxidase 8 thymidine kinase 8 GAR 8 sarcosine oxidase 7 trypsin 7 glutathione S-transferase 7 catalase 7 alcohol dehydrogenase 7 methylmalonyl-CoA mutase 6 glutamate formiminotransferase 6 adenosine deaminase 6 superoxide dismutase 6 adenosine deaminase 6 DNA methyltransferase 5 lactate dehydrogenase 5 NO synthase 5 phosphoglycerate dehydrogenase 5 dimethylglycine oxidase 5 methane monooxygenase 5 MetE 5 dihydropyrimidine dehydrogenase 5 xanthine oxidase 5 more...

Compound THF 6320 THF 6228 water 826 Dec 551 hydrogen 516 toluene 481 salt 372 sodium 312 DNA 312 nitrogen 300 pyridine 294 oxygen 292 methionine 276 potassium 262 homocysteine 251 methanol 241 serine 238 iron 224 zinc 216 dihydrofolate 212 DMF 206 benzene 205 acetonitrile 197 CO2 181 DMSO 176 copper 167 phosphate 167 ethanol 162 dichloromethane 160 iodine 160 PGA 156 hexane 141 acetone 133 bromide 133 NADPH 130 NADPH 130 boron 128 acetate 127 NADP 124 Clin 124 NH2 123 chloroform 118 10-formyltetrahydrofolate 114 cobalt 111 formaldehyde 111 5-formyltetrahydrofolate 111 formaldehyde 105 HCl 104 titanium 102 phosphorus 98 vinyl 95 calcium 95 aldehyde 95 glutamate 93 CH3-THF 92 nickel 92 phenol 90 ammonia 87 TMEDA 86 aldehyde 85 ATP 84 adenosylmethionine 83 His 76 2,6-diisopropylphenyl 76 ammonium 76 TMP 76 aluminum 73 pyrimidine 71 silicon 69 methane 69 pyrimidine 68 PEG 65 cysteine 61 Methotrexate 61 hydroxide 61 5,10-methenyltetrahydrofolate 60 glucose 60 dUMP 58 alanine 57 chromium 56 more...

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