Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: DrugBank:EXPT03052 (THF)
8,150 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein NMR 1136 Sep 608 reductase 412 dimeric 270 Mol 233 dihydrofolate reductase 232 thymidylate synthase 158 EPR 150 NADPH 130 B12 105 methionine synthase 104 C-C 94 serine hydroxymethyltransferase 88 CO2 88 ATP 84 fused 76 NADP 75 thymidylate synthetase 71 cage 67 Serine hydroxymethyltransferase 61 hormone receptor 58 ACS 54 methyltransferase 54 Dihydrofolate reductase 53 NADP+ 53 folylpolyglutamate synthetase 50 TEM 49 TMS 49 prothrombin 44 NHC 44 TOF 43 MTHFR 40 NIR 40 factor V Leiden 39 methylenetetrahydrofolate dehydrogenase 39 ESI 38 dilute 38 Boc 37 oxidoreductase 35 CHC 35 more...

Disease cancer 271 tumor 155 folate deficiency 66 hyperhomocysteinemia 65 leukemia 57 TEM 49 TEM 49 SEM 45 NHC 44 hypertension 35 colorectal cancer 35 LDA 34 dehydration 32 cardiovascular disease 30 NF2 28 breast cancer 28 HIV 28 megaloblastic anemia 26 MCF 26 carcinoma 26 stroke 26 adenocarcinoma 25 Steroids 24 homocystinuria 21 depression 20 SDS 20 CEM 20 diabetes 20 cold 20 carcinogenesis 19 Mycobacterium 18 colon cancer 18 fits 18 vascular disease 18 mole 18 mole 18 vitamin B12 deficiency 18 obesity 17 idiopathic dilated cardiomyopathy 17 anemia 16 more...

Symptom acidity 62 seizures 10 pain 7 headache 6 collapse 6 diarrhea 6 vomiting 5 fatigue 5 nausea 5 starvation 5 tremor 4 weakness 4 paraparesis 3 ataxia 3 anorexia 3 agitation 3 exhaustion 3 anesthesia 2 Halo 2 lethargy 2 pallor 2 splenomegaly 1 constipation 1 sore throat 1 shortness of breath 1 Decreased activity 1 cyanosis 1 blurred vision 1 general problem 1 thinning 1 right upper quadrant pain 1 leg pain 1 ophthalmoplegia 1 HSA 1 hemoptysis 1 iridodonesis 1 spasm 1 hunger 1 labored breathing 1 insomnia 1 more...

Drug THF 8150 TMS 49 pyridoxal phosphate 39 lysine 34 FAD 34 NADH 28 BH4 28 ascorbate 28 Leucovorin 23 NH3 22 DMAP 20 Vitamin B12 19 Asn 15 ZnCl2 13 ZnCl2 13 ZnO 12 Gel 11 PCP 11 Cobalamin 11 NaI 10 NaI 10 CrCl3 10 NaI 10 NaI 10 TiO2 9 FeCl3 8 CEC 7 CoCl2 6 EE2 6 CoCl2 6 ENT 6 PPA 6 -deoxyadenosine 5 InCl3 5 Vitamin B 5 MOF 5 PCB 5 FLP 5 SiO2 5 Ethanol 5 more...

Enzyme dihydrofolate reductase 260 thymidylate synthase 207 methionine synthase 107 serine hydroxymethyltransferase 105 methionine synthase 90 ACS 56 folylpolyglutamate synthetase 52 cyclohydrolase 50 formyltetrahydrofolate synthetase 32 methylenetetrahydrofolate reductase 31 10-formyltetrahydrofolate dehydrogenase 30 T-protein 29 demethylase 28 APC 28 glycine decarboxylase 26 methylenetetrahydrofolate reductase 26 11beta-hydroxysteroid dehydrogenase 25 complex I 23 glycinamide ribonucleotide transformylase 23 TPP 22 methylenetetrahydrofolate dehydrogenase 22 TPP 22 ERK 21 conjugase 20 HIV-1 protease 20 cystathionine beta-synthase 19 aldehyde dehydrogenase 18 methionine synthase reductase 18 lipase 17 HSD 17 dihydropteroate synthase 16 hydrogenase 16 hydrogenase 16 focal adhesion kinase 16 aldehyde dehydrogenase 15 aldehyde dehydrogenase 15 aldehyde dehydrogenase 15 aldehyde dehydrogenase 15 homocysteine methyltransferase 15 DIPP 15 more...

Compound THF 6320 THF 6228 water 826 Dec 551 hydrogen 516 toluene 481 salt 372 sodium 312 DNA 312 nitrogen 300 pyridine 294 oxygen 292 methionine 276 potassium 262 homocysteine 251 methanol 241 serine 238 iron 224 zinc 216 dihydrofolate 212 DMF 206 benzene 205 acetonitrile 197 CO2 181 DMSO 176 phosphate 167 copper 167 ethanol 162 iodine 160 dichloromethane 160 PGA 156 hexane 141 bromide 133 acetone 133 NADPH 130 NADPH 130 boron 128 acetate 127 NADP 124 Clin 124 more...

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