Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: DrugBank:EXPT03052 (THF)
8,150 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
NMR 1136
Sep 608
reductase 412
dimeric 270
Mol 233
dihydrofolate reductase 232
thymidylate synthase 158
EPR 150
NADPH 130
B12 105
methionine synthase 104
C-C 94
serine hydroxymethyltransferase 88
CO2 88
ATP 84
fused 76
NADP 75
thymidylate synthetase 71
cage 67
Serine hydroxymethyltransferase 61
more...
Disease
cancer 271
tumor 155
folate deficiency 66
hyperhomocysteinemia 65
leukemia 57
TEM 49
TEM 49
SEM 45
NHC 44
colorectal cancer 35
hypertension 35
LDA 34
dehydration 32
cardiovascular disease 30
HIV 28
breast cancer 28
NF2 28
stroke 26
megaloblastic anemia 26
carcinoma 26
more...
Symptom
acidity 62
seizures 10
pain 7
diarrhea 6
collapse 6
headache 6
nausea 5
starvation 5
vomiting 5
fatigue 5
tremor 4
weakness 4
ataxia 3
agitation 3
paraparesis 3
anorexia 3
exhaustion 3
pallor 2
anesthesia 2
lethargy 2
more...
Drug
THF 8150
TMS 49
pyridoxal phosphate 39
FAD 34
lysine 34
ascorbate 28
NADH 28
BH4 28
Leucovorin 23
NH3 22
DMAP 20
Vitamin B12 19
Asn 15
ZnCl2 13
ZnCl2 13
ZnO 12
PCP 11
Cobalamin 11
Gel 11
NaI 10
more...
Enzyme
dihydrofolate reductase 260
thymidylate synthase 207
methionine synthase 107
serine hydroxymethyltransferase 105
methionine synthase 90
ACS 56
folylpolyglutamate synthetase 52
cyclohydrolase 50
formyltetrahydrofolate synthetase 32
methylenetetrahydrofolate reductase 31
10-formyltetrahydrofolate dehydrogenase 30
T-protein 29
APC 28
demethylase 28
glycine decarboxylase 26
methylenetetrahydrofolate reductase 26
11beta-hydroxysteroid dehydrogenase 25
complex I 23
glycinamide ribonucleotide transformylase 23
TPP 22
more...
Compound
THF 6320
THF 6228
water 826
Dec 551
hydrogen 516
toluene 481
salt 372
DNA 312
sodium 312
nitrogen 300
pyridine 294
oxygen 292
methionine 276
potassium 262
homocysteine 251
methanol 241
serine 238
iron 224
zinc 216
dihydrofolate 212
more...