Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: DrugBank:EXPT03052 (
THF
)
8,150
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
NMR
1136
Sep
608
reductase
412
dimeric
270
Mol
233
dihydrofolate reductase
232
thymidylate synthase
158
EPR
150
NADPH
130
B12
105
methionine synthase
104
C-C
94
serine hydroxymethyltransferase
88
CO2
88
ATP
84
fused
76
NADP
75
thymidylate synthetase
71
cage
67
Serine hydroxymethyltransferase
61
more...
Disease
cancer
271
tumor
155
folate deficiency
66
hyperhomocysteinemia
65
leukemia
57
TEM
49
TEM
49
SEM
45
NHC
44
colorectal cancer
35
hypertension
35
LDA
34
dehydration
32
cardiovascular disease
30
HIV
28
breast cancer
28
NF2
28
stroke
26
megaloblastic anemia
26
carcinoma
26
more...
Symptom
acidity
62
seizures
10
pain
7
diarrhea
6
collapse
6
headache
6
nausea
5
starvation
5
vomiting
5
fatigue
5
tremor
4
weakness
4
ataxia
3
agitation
3
paraparesis
3
anorexia
3
exhaustion
3
pallor
2
anesthesia
2
lethargy
2
more...
Drug
THF
8150
TMS
49
pyridoxal phosphate
39
FAD
34
lysine
34
ascorbate
28
NADH
28
BH4
28
Leucovorin
23
NH3
22
DMAP
20
Vitamin B12
19
Asn
15
ZnCl2
13
ZnCl2
13
ZnO
12
PCP
11
Cobalamin
11
Gel
11
NaI
10
more...
Enzyme
dihydrofolate reductase
260
thymidylate synthase
207
methionine synthase
107
serine hydroxymethyltransferase
105
methionine synthase
90
ACS
56
folylpolyglutamate synthetase
52
cyclohydrolase
50
formyltetrahydrofolate synthetase
32
methylenetetrahydrofolate reductase
31
10-formyltetrahydrofolate dehydrogenase
30
T-protein
29
APC
28
demethylase
28
glycine decarboxylase
26
methylenetetrahydrofolate reductase
26
11beta-hydroxysteroid dehydrogenase
25
complex I
23
glycinamide ribonucleotide transformylase
23
TPP
22
more...
Compound
THF
6320
THF
6228
water
826
Dec
551
hydrogen
516
toluene
481
salt
372
DNA
312
sodium
312
nitrogen
300
pyridine
294
oxygen
292
methionine
276
potassium
262
homocysteine
251
methanol
241
serine
238
iron
224
zinc
216
dihydrofolate
212
more...