Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: DrugBank:EXPT02558 (
Propofol
)
2,109
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
136
GABA
101
ASA
98
Mol
56
caspase-3
42
TNF
36
tumor necrosis factor
32
lipopolysaccharide
29
ATP
29
GABA(A) receptor
24
cytokine
23
IL-6
22
CA1
22
Bcl-2
21
CO2
18
NMDA receptor
17
superoxide dismutase
15
cytochrome P450
15
p38
15
nitric oxide synthase
15
more...
Disease
depression
118
ischemia
63
cancer
50
tumor
38
hypertension
37
stroke
32
status epilepticus
32
epilepsy
30
amnesia
27
cerebral ischemia
25
SEM
23
heart failure
21
sepsis
21
cognitive impairment
21
sepsis
21
myocardial ischemia
20
renal failure
19
delirium
19
fits
16
malignant hyperthermia
14
more...
Symptom
anesthesia
970
pain
173
analgesia
89
seizures
76
nausea and vomiting
44
Sedation
38
vomiting
38
agitation
34
nausea
30
discomfort
24
discomfort
20
hypothermia
13
cough
13
hypercapnia
11
collapse
11
myoclonus
9
hepatomegaly
6
sleepiness
5
respiratory distress
5
tachypnea
5
more...
Drug
Propofol
2109
Fentanyl
33
Monit
30
Thiopentone
10
MAP
9
caffeine
7
ROS
7
Cardiovasc
6
vitamin E
6
ascorbate
5
Disoprivan
5
Methohexitone
5
nitroglycerin
5
ENT
4
Clonidine
4
Ringer's solution
4
CaCl2
3
Cremophor EL
3
Histamine
3
ICI
3
more...
Enzyme
mitogen-activated protein kinase
32
caspase-3
32
protein kinase
26
superoxide dismutase
16
protein kinase C
13
luciferase
13
ERK
10
BIS
10
caspase-9
10
catalase
9
peroxidase
9
UDP-glucuronosyltransferase
8
lactate dehydrogenase
8
MAP
8
glutathione peroxidase
8
creatine kinase
7
xanthine oxidase
6
caspase-8
6
phosphoinositide 3-kinase
6
NADPH oxidase
5
more...
Compound
Propofol
2109
oxygen
233
Dec
144
Clin
113
GABA
103
GABA
101
ASA
99
calcium
82
water
76
Midazolam
46
sodium
44
CO2
40
nitric oxide
40
glucose
37
TNF
36
MTT
35
gamma-aminobutyric acid
34
Ketamine
32
N2O
32
glutamate
32
more...