Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: DrugBank:EXPT02427 (Atropine)
 3,300 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
muscarinic receptor 243
Sep 233
substance P 131
cholecystokinin 109
acetylcholinesterase 96
gastrin 89
insulin 80
somatostatin 69
ATP 68
5-hydroxytryptamine 65
secretin 58
AMP 44
pancreatic polypeptide 43
amylase 41
CCK 41
nitric oxide synthase 38
GABA 38
gut 37
polypeptide 34
glucagon 33
bradykinin 33
adenylate cyclase 29
Mol 29
nodal 28
cyclooxygenase 27
Gen 27
vasopressin 26
bombesin 25
motilin 25
NK1 24
vasoactive intestinal peptide 22
choline acetyltransferase 22
neurotensin 22
phosphodiesterase 20
NK2 19
vasoactive intestinal peptide (VIP) 19
VIP 18
CO2 17
Met 16
CA1 16
mast cell 15
angiotensin II 15
calcium channel 15
HT3 15
Pol 15
NMS 14
calcitonin 14
muscarinic acetylcholine receptor 14
neuropeptide Y 13
esterase 13
5-HT3 receptor 13
nicotinic acetylcholine receptor 12
guanylate cyclase 12
EFS 12
M3 muscarinic receptor 12
GTP 12
adenylyl cyclase 12
ATPase 11
opioid receptor 11
neurokinin B 11
pepsinogen 11
TRH 11
alpha, beta 10
AChE 10
ICS 9
calmodulin 9
growth hormone 9
beta 1 9
albumin 9
collagenase 9
ASA 9
ACTH 9
gastrin-releasing peptide 9
prolactin 9
sodium channel 9
galanin 9
P2X 8
NMDA receptor 8
beta-endorphin 8
ADP 8
pituitary adenylate cyclase-activating polypeptide 8
oxytocin 8
neutral endopeptidase 8
5-HT4 8
rat) 8
ghrelin 8
NKA 8
NK3 receptor 7
axonal 7
acetylcholine receptor 7
serum albumin 7
5-HT1A 7
dynorphin 7
PAM 7
5-HT4 receptor 7
orexin 7
olfactory 7
SRIF 7
muscarinic M2 receptor 6
lipase 6
CCK-B receptor 6
cage 6
CCK8 6
PCP 6
kallikrein 6
peptide YY 6
Net 6
Ang II 6
Vasoactive intestinal peptide 6
PRL 6
CD57 6
5-HT receptor 6
corticotropin-releasing factor 6
lipoxygenase 6
IP1 5
short form 5
neuronal nitric oxide synthase 5
COX-2 5
myosin 5
adenosine receptor 5
phospholipase A2 5
5-lipoxygenase 5
thyrotropin-releasing hormone 5
NK-2 receptor 5
myosin light chain 5
SCH 5
GHRH 5
tyrosine hydroxylase 5
strabismus 5
NEMO 5
butyrylcholinesterase 5
glycoprotein 5
nerve growth factor 5
membrane-bound 5
NKB 5
She 5
Ghrelin 5
ANOVA 5
Mal 5
vascular endothelium 4
COX 4
ms2 4
MAC 4
CA3 4
cardiac muscle 4
COX-1 4
Bcl-2 4
gastric inhibitory polypeptide 4
lysozyme 4
CCK-A 4
REM 4
protein kinase C inhibitor 4
mucin 4
Choline acetyltransferase 4
5-HT2A 4
IVA 4
ATR 4
Thyrotropin-releasing hormone 4
renin 4
PLC 4
more...
Disease
depression 86
hypertension 53
NAME 38
asthma 35
cold 32
pertussis 27
stroke 27
fits 27
SEM 26
atrioventricular block 25
myopia 24
hypoglycemia 23
diabetes 21
ventricular fibrillation 20
ischemia 20
uterus 19
urethra 17
Pancreas 16
parasympathomimetic 16
Pancreas 16
NMS 14
NMS 14
coronary artery disease 14
bronchospasm 14
myocardial infarction 13
cancer 12
duodenal ulcer 11
acute myocardial infarction 10
catalepsy 10
Bezold 10
hyperglycemia 10
tumor 10
coma 10
incontinence 10
Esophageal 10
myocardial ischemia 10
epilepsy 10
Evans 10
neuroblastoma 9
strabismus 9
incontinence 9
ICS 9
pulmonary edema 9
celiac disease 9
xerostomia 9
sinus tachycardia 8
respiratory failure 8
Alzheimer's disease 8
heart failure 8
sympathomimetic 8
gastric ulcer 8
chronic obstructive pulmonary disease 7
PAM 7
heart block 7
PCP 7
delirium 6
suicide 6
cycloplegia 6
gastroesophageal reflux disease 6
confusion 6
multiple endocrine neoplasia 6
anaphylaxis 6
status epilepticus 6
refractive error 6
cholera 6
bradyarrhythmia 6
supraventricular tachycardia 6
dehydration 6
varices 6
Wenckebach 6
dyskinesia 5
pancreatitis 5
obesity 5
amblyopia 5
Blocking 5
paroxysmal supraventricular tachycardia 5
SCH 5
neuropathy 5
heart disease 5
disinhibition 4
mole 4
mole 4
aggressiveness 4
Anterior 4
Bladder 4
ICC 4
esotropia 4
amnesia 4
Bladder 4
conjunctiva 4
gastric lesion 4
psychosis 4
MAC 4
hyperopia 4
sick sinus syndrome 4
cholecystitis 4
ICC 4
IVA 4
hallucinations 4
flutter 4
sepsis 4
breast cancer 4
glaucoma 4
Bladder 4
schizophrenia 3
colon cancer 3
cystitis 3
ATM 3
cystic fibrosis 3
abortion 3
sudden infant death syndrome 3
autonomic neuropathy 3
intraocular pressure 3
rhinitis 3
cornea 3
achalasia 3
sclera 3
inferior myocardial infarction 3
memory impairment 3
SMS 3
Parkinson's disease 3
Luminal 3
psychological stress 3
neurogenic bladder 3
cerebral ischemia 3
gastroparesis 3
aggression 3
Chagas 3
cardiomyopathy 3
Wolff-Parkinson-White syndrome 3
ureter 3
mitral valve prolapse 3
tetanus 3
acute pancreatitis 3
SDS 3
Still 3
Insulin hypoglycemia 3
bronchorrhea 3
Neuromuscular blockade 3
hyperinsulinemia 2
lactic acidosis 2
tumor progression 2
major depressive disorder 2
obsessive-compulsive disorder 2
tardive dyskinesia 2
complex partial seizures 2
NPC 2
glucose intolerance 2
carcinoma 2
stress ulcer 2
sepsis 2
disorientation 2
hairy cell leukemia 2
cognitive impairment 2
Rett syndrome 2
coronary heart disease 2
pancreatic cancer 2
antidiuresis 2
anemia 2
herpes simplex 2
more...
Symptom
anesthesia 153
seizures 38
pain 35
vomiting 30
analgesia 25
hypothermia 25
tremor 25
syncope 19
nausea 15
diarrhea 13
spasm 12
cough 10
chest pain 10
dizziness 9
acidity 9
weakness 9
constipation 8
respiratory distress 8
agitation 8
tachypnea 8
sleepiness 7
fatigue 7
collapse 7
nausea and vomiting 6
angina 6
blurred vision 6
headache 6
hypercapnia 6
sinus pressure 4
heartburn 4
myoclonus 4
abdominal cramps 4
dyspnea 3
acute stress 3
ataxia 3
POA 3
shortness of breath 2
exhaustion 2
cyanosis 2
belching 2
pallor 2
paresthesia 2
flushing 2
fasciculation 2
hunger 2
discomfort 2
myalgia 2
twitching 2
asynergy 2
thinning 2
discomfort 2
urinary frequency 2
giddiness 2
vertigo 2
neuralgia 2
giddiness 2
nasal discharge 1
starvation 1
Intestinal spasm 1
numbness 1
stridor 1
Psychiatric symptoms 1
rhinorrhea 1
anorexia 1
despair 1
oliguria 1
tinnitus 1
dystonia 1
Airway constriction 1
dysarthria 1
nasal congestion 1
dental pain 1
torticollis 1
bigeminal 1
presyncope 1
polyuria 1
tingling 1
tonic-clonic seizure 1
asthenia 1
frequent urination 1
insomnia 1
chest tightness 1
retching 1
vasovagal attacks 1
sore throat 1
erythema 1
syncopal episodes 1
thirsty 1
distraction 1
dry skin 1
colic 1
incoordination 1
orofacial pain 1
skin irritation 1
atypical chest pain 1
hyperoxia 1
excessive sweating 1
acute pain 1
photophobia 1
lethargy 1
muscle rigidity 1
abdominal pain 1
chorea 1
sneezing 1
clonus 1
Drug
Atropine 3300
Histamine 37
Phentolamine 37
Indomethacin 30
Nephron 28
Pilocarpine 22
Cardiovasc 21
Scopolamine 19
Cimetidine 18
Cimetidine 18
caffeine 17
Clonidine 16
Reserpine 15
CaCl2 14
Tubocurarine 12
CaCl2 12
CaCl2 12
Guanethidine 10
Cisapride 10
Apomorphine 9
Atropine sulfate 9
Secretin 9
Theophylline 9
Ouabain 8
DFP 8
Sodium nitroprusside 7
Loxiglumide 7
Glucagon 6
Fentanyl 6
PCP 6
Diphenhydramine 6
Gallamine 6
Domperidone 5
Atenolol 5
Ethanol 5
nitroglycerin 5
citric acid 4
Methylene blue 4
MAP 4
Visken 4
ICI 4
Captopril 4
Tropicamide 3
EDR 3
Adenosine triphosphate 3
Gel 3
Xylocaine 3
Calcium gluconate 3
Pralidoxime 3
Sulpiride 3
Ranitidine 3
Forskolin 3
Hyoscyamine 3
Medetomidine 3
Digitalis 3
Monit 3
Portal 2
Xylocaine 2
Salbutamol 2
Ringer's solution 2
Emodin 2
Kainic acid 2
Innovar 2
Nadolol 2
Timolol 2
DEL 2
Xylocaine 2
Calcium chloride 2
APD 2
CTX 2
Propofol 2
THA 2
Phenytoin 2
balanced salt solution 2
Hyoscyamine 2
Emodin 2
Alanine 2
Ipratropium bromide 2
KCL 2
CDP 2
9-THC 2
Leaf 2
Gastro 2
Rize 1
Tolamolol 1
Renzapride 1
Kenyan 1
DMI 1
PNT 1
Tegaserod 1
Octapressin 1
CTX 1
Dibenzyline 1
Fructose 1
Brompheniramine 1
Hypaque 1
NaI 1
L 364718 1
Artane 1
Periactin 1
Timoprazole 1
Codeine 1
CSF 1
Pentolinium 1
CTX 1
Amiloride 1
Angiotensin II 1
Amiloride 1
Thiopentone 1
Papaverine 1
Indoramin 1
Atipamezole 1
NADH 1
Arfonad 1
Velban 1
Growth hormone 1
Benzonatate 1
NaI 1
Gatifloxacin 1
Alaproclate 1
Ipecac 1
Timiperone 1
Tegaserod 1
TMS 1
Methohexitone 1
Areca 1
IL-2 1
CEC 1
Cyclogyl 1
Hydrochlorothiazide 1
Dial 1
CPR 1
NH3 1
Indapamide 1
Fosphenytoin 1
Fenoterol 1
DHT 1
Vinpocetine 1
Ammonium chloride 1
Loratadine 1
Regadenoson 1
Doyle 1
Kaolin 1
Tiotidine 1
Rutin 1
Enalaprilat 1
NaI 1
Phosphoramidon 1
Inversine 1
Codeine 1
Isoptin 1
Cyclogyl 1
Iodipamide 1
Arfonad 1
Procaine hydrochloride 1
Aprotinin 1
Artane 1
Cytidine 1
Sodium metabisulfite 1
Dazoxiben 1
more...
Enzyme
acetylcholinesterase 170
cholinesterase 100
adenylate cyclase 29
choline acetyltransferase 22
protein kinase C 22
phosphodiesterase 20
pepsin 17
phospholipase C 17
guanylate cyclase 15
ATPase 14
trypsin 14
protein kinase 12
CD10 10
NO synthase 10
collagenase 9
PAM 7
kallikrein 7
lipoxygenase 6
PCP 6
lipase 6
ERK 5
tyrosine hydroxylase 5
phospholipase A2 5
mitogen-activated protein kinase 4
renin 4
lysozyme 4
peroxidase 4
NOS 4
monoamine oxidase 4
myosin light chain kinase 3
NADPH-diaphorase 3
neuropathy target esterase 3
MAP 3
chymotrypsin 3
lactate dehydrogenase 3
phosphorylase 3
ACE 3
creatine kinase 3
AMPK 3
caspase-2 2
PI-PLC 2
PDE 2
CPR 2
prostaglandin synthetase 2
caspase-2 2
tissue kallikrein 2
beta-glucuronidase 2
luciferase 2
tryptophan hydroxylase 2
glucose-6-phosphatase 1
hyaluronidase 1
PKG 1
phosphatidylinositol 4-kinase 1
hyaluronidase 1
SST 1
pyruvate dehydrogenase 1
GRK2 1
oxoglutarate dehydrogenase 1
MMP 1
phospholipase D 1
diaphorase 1
thioredoxin reductase 1
arginase 1
ornithine decarboxylase 1
histidine decarboxylase 1
diamine oxidase 1
aequorin 1
transpeptidase 1
pyruvate dehydrogenase 1
cGMP phosphodiesterase 1
phosphoenolpyruvate carboxykinase 1
LDT 1
phosphoenolpyruvate carboxykinase 1
catalase 1
AMP-activated protein kinase 1
ADH 1
aspartate aminotransferase 1
elastase 1
pyruvate dehydrogenase 1
phosphatidylinositol 3-kinase 1
gamma-glutamyl transpeptidase 1
DFPase 1
tyrosine aminotransferase 1
phosphoenolpyruvate carboxykinase 1
argininosuccinate synthetase 1
PWD 1
arachidonate 5-lipoxygenase 1
botulinum neurotoxin 1
PRA 1
papain 1
alpha-ketoglutarate dehydrogenase 1
SPT 1
alanine aminotransferase 1
SPT 1
alcohol dehydrogenase 1
caspase-3 1
protein phosphatase 2A 1
atropine esterase 1
alpha-amylase 1
ACS 1
neuraminidase 1
proteasome 1
cytochrome oxidase 1
FFT 1
monoacylglycerol lipase 1
phosphoglucomutase 1
Alternating 1
kynurenine formamidase 1
Compound
Atropine 3300
Dec 238
calcium 224
ACh 211
sodium 153
noradrenaline 150
water 137
Clin 129
arginine 99
nitric oxide 84
oxygen 81
Carbachol 81
Propranolol 79
Propranolol 79
Hexamethonium 75
sulfate 73
Tetrodotoxin 72
ATP 68
5-HT 67
glucose 67
potassium 58
cAMP 57
cGMP 56
Physostigmine 55
DAMP 52
DAMP 51
AMP 44
Pirenzepine 42
Nicotine 40
GABA 40
GABA 39
phosphate 38
Adrenal 38
ethanol 38
Histamine 37
glutamate 35
bromide 33
Isoproterenol 32
salt 31
Cardiol 30
Indomethacin 30
His 29
nitrate 28
Norepinephrine 28
CO2 27
QNB 26
tyrosine 25
HCl 25
Neostigmine 23
methionine 23
Pilocarpine 22
Naloxone 22
Morphine 21
Oxotremorine 21
gamma-aminobutyric acid 21
PGE2 20
Methysergide 19
caffeine 18
Adenosine 18
Methacholine 18
Bethanechol 17
PAM 17
SEE 17
galactose 17
Metoclopramide 17
piperidine 17
piperidine 17
Prazosin 16
carbonate 16
tryptophan 16
tryptophan 15
acetic acid 15
Lidocaine 15
TRH 15
Reserpine 15
Theophylline 15
Substance P 15
Mecamylamine 15
acetate 14
Dopamine 14
CaCl2 14
tryptophan 13
prostaglandin E1 13
Phe 13
GMP 13
GTP 13
Yohimbine 13
barium 13
tryptophan 13
Muscarine 12
Glycopyrrolate 12
N2O 12
Tubocurarine 12
Insulin 12
Neurotensin 11
iodine 11
Metiamide 11
ASA 11
Atropine sulfate 11
Mg2+ 11
DMPP 11
glutamic acid 11
Verapamil 11
DMPP 11
Haloperidol 10
Verapamil 10
Guanethidine 10
prostacyclin 10
nitrogen 10
Salt 10
Cisapride 10
Haloperidol 10
Choline 10
Secretin 9
Dobutamine 9
ACTH 9
leucine 9
Cocaine 9
NH2 9
Soman 9
ADP 8
Capsaicin 8
Pac 8
Ouabain 8
TSH 8
pyridine 8
ADP 8
ADP 8
hydrogen 8
cyanide 8
methylhistamine 8
Diazepam 8
Phenoxybenzamine 8
NMDA 8
Ile 8
Tetraethylammonium 8
methanol 8
Phenylephrine 8
PEG 7
isoleucine 7
Gly 7
Mepyramine 7
Ach 7
Pentagastrin 7
Chlorpheniramine 7
PAM 7
PAM 7
palmitic acid 7
Arecoline 7
Droperidol 7
Chlorpheniramine 7
isoleucine 7
sodium chloride 6
Ketamine 6
hydroxide 6
Gallamine 6
Pentobarbital 6
lysine 6
Nifedipine 6
TEA 6
more...