Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: DrugBank:EXPT01983 (
K-252a
)
343
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
nerve growth factor
72
tyrosine kinase
70
protein kinase inhibitor
53
ATP
33
brain-derived neurotrophic factor
33
neurotrophin
32
calmodulin
23
Mol
22
p75NTR
18
phosphatase
18
Sep
18
protein phosphatase
16
NGF
16
neurotrophin-3
16
AMP
13
p75
13
threonine
12
myosin light chain kinase
12
ATPase
12
epidermal growth factor
12
more...
Disease
pheochromocytoma
21
tumor
15
cancer
10
leukemia
6
neuroblastoma
4
cholera
4
CEP
4
acute myeloid leukemia
3
Parkinson's disease
3
cold
3
Alzheimer's disease
3
depression
3
LTD
2
pertussis
2
melanoma
2
Blocking
2
squamous cell carcinoma
2
carcinoma
2
anaphylaxis
2
stomatitis
2
more...
Symptom
pain
4
starvation
3
hyperoxia
2
collapse
1
analgesia
1
diarrhea
1
Drug
K-252a
343
p75
13
Histamine
4
lysine
2
balanced salt solution
2
CaCl2
2
CaCl2
2
CaCl2
2
Asn
2
ADR
1
ABC
1
Leaf
1
Forskolin
1
Angiotensin II
1
Amiloride
1
Meth
1
Sulpiride
1
ROS
1
Fluspirilene
1
MAP
1
more...
Enzyme
protein kinase
109
protein kinase C
83
mitogen-activated protein kinase
23
calcineurin
17
myosin light chain kinase
13
ATPase
13
AMPK
11
CaMKII
10
phospholipase C
9
ERK
8
MEK
7
choline acetyltransferase
6
trypsin
5
phosphatidylinositol 3-kinase
5
phospholipase A2
4
CEP
4
CEP
4
adenylate cyclase
4
P-glycoprotein
3
alkaline phosphatase
3
more...
Compound
calcium
68
tyrosine
40
ATP
33
Dec
29
acetate
28
Staurosporine
20
Staurosporine
20
DNA
18
cAMP
16
threonine
15
AMP
13
sodium
12
GTP
12
serine
12
Mg2+
10
manganese
9
phosphate
9
oxygen
8
GDP
8
PMA
7
more...