Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: DrugBank:EXPT01713 (Heme)
 3,109 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
HO-1 503
heme oxygenase-1 487
hemoglobin 313
Mol 238
Sep 197
HO-2 154
erythroid 131
ferritin 103
myoglobin 102
catalase 99
cytochrome 91
peroxidase 88
Nrf2 87
cytochrome c 86
lipopolysaccharide 79
microsomal 78
cytokine 76
NADPH 74
tumor necrosis factor 66
superoxide dismutase 66
more...
Disease
cancer 144
ischemia 128
tumor 76
Alzheimer's disease 70
hypertension 67
atherosclerosis 62
GSH 57
malaria 50
diabetes 44
sepsis 42
sepsis 41
stroke 38
anemia 37
hepatocellular carcinoma 30
Parkinson's disease 28
iron deficiency 27
myocardial infarction 27
sickle cell disease 26
carcinogenesis 25
tumor growth 24
more...
Symptom
hyperoxia 17
pain 14
respiratory distress 10
starvation 9
anesthesia 7
splenomegaly 5
seizures 4
abdominal pain 3
fatigue 3
ataxia 3
functional recovery 3
weakness 3
hypercapnia 3
collapse 3
acute pain 2
skin damage 2
Ear swelling 1
hepatomegaly 1
exertional dyspnea 1
nausea and vomiting 1
more...
Drug
Heme 3109
ROS 41
ALA 31
ascorbate 28
lysine 15
NADH 15
Nitric Oxide 14
CoCl2 11
CoCl2 11
FAD 9
vitamin E 8
Gel 8
Albumin 7
CSF 6
IFN-gamma 5
Dermatol 5
DNase I 5
pyridoxal phosphate 4
Indomethacin 4
Simvastatin 4
more...
Enzyme
heme oxygenase 332
peroxidase 118
catalase 105
mitogen-activated protein kinase 92
superoxide dismutase 80
ALA synthase 80
guanylate cyclase 60
biliverdin reductase 56
ferrochelatase 53
luciferase 44
ERK 41
protein kinase 38
caspase-3 36
NADPH oxidase 30
cytochrome oxidase 30
protein kinase C 30
NADPH oxidase 28
NO synthase 26
NQO1 22
alanine aminotransferase 21
more...
Compound
Heme 3109
iron 977
CO2 582
oxygen 550
Dec 229
His 185
DNA 177
nitric oxide 176
hydrogen 164
zinc 140
water 132
tin 128
cobalt 104
cysteine 87
sodium 80
NADPH 74
NADPH 74
Clin 73
glucose 69
Hemin 63
more...