Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: DrugBank:EXPT01586 (
G418
)
2,237
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The gene coding for TNF-alpha was introduced into
DNL
of human oral squamous carcinoma by retroviral-mediated gene transduction, and experiments proved that the gene had been introduced into the
DNL
and the
DNL
could secrete TNF-alpha of high activity with PCR analysis, bioactivity analysis of TNF-alpha, selection test in
G418
. Cytotoxicity of gene-transduced and nontransduced
DNL
to Tca8113 cell was compared with MTT method. The result showed that cytotoxicity of the former was higher than that of the latter.
...
PMID:[Experimental study on antitumor effect in vitro of modified DNL of oral squamous cell carcinoma with TNF-alpha gene]. 1118 81
