Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: DrugBank:EXPT00568 (ascorbate)
23,072 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
catalase 1815
superoxide dismutase 1758
Sep 1541
GSH 1355
glutathione peroxidase 860
Mol 767
glutathione reductase 693
peroxidase 640
collagen 615
NADPH 493
NADH 442
ATP 432
cytochrome c 368
hemoglobin 347
SOD 328
reductase 327
microsomal 326
insulin 323
cytochrome 312
ROS 295
ADP 281
alkaline phosphatase 279
B12 262
albumin 247
ferritin 245
NMR 227
antioxidant enzyme 224
serum albumin 214
xanthine oxidase 213
lactate dehydrogenase 212
EPR 209
ESR 195
ATPase 185
transferrin 184
NAD 182
aspartate aminotransferase 157
caspase-3 156
CO2 154
glutathione S-transferase 149
Catalase 140
APE1 133
CAT 130
nitric oxide synthase 128
SVCT2 123
SDS 120
myeloperoxidase 120
endoplasmic reticulum 117
oxidoreductase 115
Pseudomonas 114
HDL 113
cytochrome b 112
membrane-bound 111
ceruloplasmin 108
alanine aminotransferase 105
NADP 103
cytokine 100
glucose-6-phosphate dehydrogenase 100
cytochrome c oxidase 100
gut 99
Superoxide dismutase 98
Bot 96
p53 94
ubiquinone 92
spermatozoa 90
lipoxygenase 90
C-reactive protein 89
osteogenic 89
TNF 89
FRAP 88
lipopolysaccharide 87
dopamine beta-hydroxylase 86
thymus 85
cytochrome P450 85
polypeptide 82
IL-6 81
cytochrome P-450 80
ash 79
AMP 77
methemoglobin 74
myoglobin 72
more...
Disease
cancer 1656
GSH 1355
tumor 582
diabetes 520
carcinogenesis 366
vitamin C deficiency 343
atherosclerosis 332
scurvy 321
cardiovascular disease 286
hypertension 275
cold 247
ischemia 238
obesity 229
Alzheimer's disease 202
malnutrition 187
anemia 182
gastric cancer 155
breast cancer 140
cataract 139
carcinoma 136
lung cancer 123
SDS 120
stroke 109
iron deficiency 101
Parkinson's disease 98
type 2 diabetes 98
hyperglycemia 96
coronary heart disease 95
depression 95
sepsis 93
sepsis 92
leukemia 85
melanoma 84
hepatocellular carcinoma 83
hypovitaminosis 82
ash 81
colorectal cancer 80
iron overload 79
aqueous humor 77
myocardial infarction 71
tumor growth 69
adenocarcinoma 69
heart disease 69
plaque 68
neuroblastoma 68
colon cancer 66
asthma 66
RDA 65
hypercholesterolemia 64
SEM 64
prostate cancer 62
osteoporosis 62
renal disease 61
metabolic syndrome 59
myocardial ischemia 58
dehydration 58
NAME 58
HIV 53
chronic disease 53
gastritis 50
pancreatic cancer 50
squamous cell carcinoma 49
mole 48
mole 48
infectious diseases 48
tuberculosis 47
heart failure 46
dementia 46
preeclampsia 45
iron deficiency anemia 45
arthritis 45
chronic renal failure 44
rheumatoid arthritis 43
pneumonia 43
coronary artery disease 43
MCF 43
cornea 42
AIDS 40
atrophic gastritis 39
malaria 39
more...
Symptom
acidity 167
pain 112
overweight 97
fatigue 72
diarrhea 44
anesthesia 43
seizures 41
weakness 35
starvation 32
anorexia 25
collapse 25
hyperoxia 24
angina 21
skin damage 20
exhaustion 19
cough 19
respiratory distress 17
chills 16
thinning 15
hypothermia 15
headache 14
erythema 14
vomiting 13
nausea 12
dyspnea 12
arthralgia 12
constipation 10
bone pain 9
shortness of breath 9
cyanosis 9
wheezing 9
myalgia 9
tremor 9
HSA 9
lethargy 8
agitation 8
Blanching 8
functional recovery 7
ataxia 6
Ill 6
hepatomegaly 6
chest pain 6
flushing 5
inanition 5
spasm 5
sleepiness 5
hypotonia 5
nausea and vomiting 5
dry skin 4
analgesia 4
back pain 4
discomfort 4
vertigo 4
memory loss 4
eds 4
acute stress 4
hunger 4
Anoxia 4
knee pain 4
hypercapnia 4
insomnia 4
colic 3
tingling 3
discomfort 3
abdominal pain 3
bradykinesia 3
limb pain 3
stigma 3
bitter taste 3
nasal congestion 3
apathy 3
pallor 3
Depressive symptoms 3
tinnitus 3
polydipsia 3
tachypnea 3
paraparesis 3
asthenia 3
halitosis 2
sore throat 2
more...
Drug
ascorbate 23072
vitamin E 2750
NADH 441
ROS 295
niacin 269
Vitamin E 244
lysine 192
Glutathione 156
Dermatol 96
citric acid 87
Vitamin A 83
caffeine 63
Leaf 54
FeCl3 52
Cardiovasc 52
Capsicum 43
lactose 43
FAD 37
Sodium ascorbate 37
Nitric Oxide 36
Ethanol 35
Tocopherol 34
Gel 33
pyridoxal phosphate 31
nitroglycerin 29
THF 28
Heme 28
Mutagen 26
ALA 26
CSF 24
L-tyrosine 23
Riboflavin 21
MAP 20
Nephron 19
Asn 18
CaCl2 17
CaCl2 17
Indomethacin 17
TAC 17
Vitamin B12 17
CaCl2 17
CTX 16
Vitamin K 16
Monit 16
Albumin 16
Carotenoid 16
BH4 15
Desferal 15
Fructose 15
ZnO 15
Adriamycin 15
Desferal 15
IFN-gamma 14
EE2 13
Rutin 13
Nephron 13
Dial 13
Vitamin B 13
NH3 12
Bifidobacterium 12
EPA 12
NBT 12
Spectrum 12
CoCl2 11
IL-2 11
Aloe 11
CoCl2 11
PCB 10
Methylene blue 10
ampicillin 10
HCH 10
ENT 9
CAM 9
Asthma 9
-deoxyadenosine 8
Glycyrrhiza 7
Sodium nitroprusside 7
Arsenic trioxide 7
Apomorphine 7
DPA 7
more...
Enzyme
superoxide dismutase 1985
catalase 1899
glutathione peroxidase 888
peroxidase 843
glutathione reductase 692
ascorbate peroxidase 615
dehydroascorbate reductase 304
alkaline phosphatase 279
SOR 250
xanthine oxidase 226
lactate dehydrogenase 224
glutathione S-transferase 221
alanine aminotransferase 204
aspartate aminotransferase 202
ATPase 199
ascorbate oxidase 194
cytochrome oxidase 149
ceruloplasmin 136
mitogen-activated protein kinase 121
caspase-3 120
glucose-6-phosphate dehydrogenase 116
NADPH oxidase 110
NADPH oxidase 103
tyrosinase 94
lipoxygenase 94
prolyl hydroxylase 94
creatine kinase 92
dopamine beta-hydroxylase 91
complex I 88
trypsin 81
diaphorase 80
ERK 75
succinate dehydrogenase 67
gamma-glutamyl transpeptidase 66
CPR 64
NO synthase 61
ACS 59
protein kinase 59
collagenase 59
lysozyme 57
NQO1 55
acetylcholinesterase 54
glucose oxidase 46
AST 45
protein kinase C 42
PARP 41
thrombin 41
heme oxygenase 38
guanylate cyclase 36
peroxiredoxin 35
glutamine synthetase 35
PAL 35
acid phosphatase 35
malate dehydrogenase 34
lactonase 34
GLO 34
phospholipase A2 34
isocitrate dehydrogenase 34
thioredoxin reductase 33
isocitrate dehydrogenase 32
proteasome 31
PAM 31
nitrite reductase 31
cytochrome c peroxidase 29
caspase-9 29
glyceraldehyde-3-phosphate dehydrogenase 28
phosphorylase 28
nitrate reductase 27
hydrogenase 27
hydrogenase 27
nitrate reductase 26
nitrate reductase 26
gamma-glutamylcysteine synthetase 26
nitrate reductase 26
nitrate reductase 26
tyrosine hydroxylase 26
aldose reductase 26
nitrate reductase 26
glyoxalase II 26
pepsin 25
more...
Compound
oxygen 3617
Ascorbic acid 2556
iron 2386
water 2061
sodium 1882
Dec 1603
DNA 1524
GSH 1480
GSH 1479
hydrogen 1446
calcium 1332
copper 1288
glucose 1061
H2O2 996
Clin 945
zinc 905
nitric oxide 764
phosphate 752
cysteine 648
selenium 566
potassium 540
NADPH 494
NADPH 493
nitrogen 477
salt 449
NADH 440
ATP 432
proline 399
ethanol 376
retinol 369
sulfate 364
EDTA 356
EDTA 351
acetate 342
galactose 310
vitamin D 304
Vitamin E 301
glutamate 297
ADP 293
His 293
ADP 282
ADP 281
arginine 276
nitrate 271
DPPH 263
manganese 263
cyanide 259
CO2 248
tyrosine 246
GSSG 241
lysine 237
methionine 233
MDA 225
NAD 224
Cu(II) 221
urea 217
cadmium 209
N-acetylcysteine 208
phosphorus 195
superoxide radical 191
creatinine 184
NAD 182
oxalate 182
2-oxoglutarate 181
tryptophan 181
tryptophan 178
tryptophan 176
tryptophan 176
gallic acid 166
iodine 161
phenol 155
nicotinamide 152
chromium 151
NADP 148
alanine 146
methanol 140
ammonium 139
phenazine 130
CAT 130
CAT 130
more...