Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: DrugBank:EXPT00568 (
ascorbate
)
23,072
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
catalase
1815
superoxide dismutase
1758
Sep
1541
GSH
1355
glutathione peroxidase
860
Mol
767
glutathione reductase
693
peroxidase
640
collagen
615
NADPH
493
NADH
442
ATP
432
cytochrome c
368
hemoglobin
347
SOD
328
reductase
327
microsomal
326
insulin
323
cytochrome
312
ROS
295
ADP
281
alkaline phosphatase
279
B12
262
albumin
247
ferritin
245
NMR
227
antioxidant enzyme
224
serum albumin
214
xanthine oxidase
213
lactate dehydrogenase
212
EPR
209
ESR
195
ATPase
185
transferrin
184
NAD
182
aspartate aminotransferase
157
caspase-3
156
CO2
154
glutathione S-transferase
149
Catalase
140
APE1
133
CAT
130
nitric oxide synthase
128
SVCT2
123
SDS
120
myeloperoxidase
120
endoplasmic reticulum
117
oxidoreductase
115
Pseudomonas
114
HDL
113
cytochrome b
112
membrane-bound
111
ceruloplasmin
108
alanine aminotransferase
105
NADP
103
cytokine
100
glucose-6-phosphate dehydrogenase
100
cytochrome c oxidase
100
gut
99
Superoxide dismutase
98
Bot
96
p53
94
ubiquinone
92
spermatozoa
90
lipoxygenase
90
C-reactive protein
89
osteogenic
89
TNF
89
FRAP
88
lipopolysaccharide
87
dopamine beta-hydroxylase
86
thymus
85
cytochrome P450
85
polypeptide
82
IL-6
81
cytochrome P-450
80
ash
79
AMP
77
methemoglobin
74
myoglobin
72
more...
Disease
cancer
1656
GSH
1355
tumor
582
diabetes
520
carcinogenesis
366
vitamin C deficiency
343
atherosclerosis
332
scurvy
321
cardiovascular disease
286
hypertension
275
cold
247
ischemia
238
obesity
229
Alzheimer's disease
202
malnutrition
187
anemia
182
gastric cancer
155
breast cancer
140
cataract
139
carcinoma
136
lung cancer
123
SDS
120
stroke
109
iron deficiency
101
Parkinson's disease
98
type 2 diabetes
98
hyperglycemia
96
coronary heart disease
95
depression
95
sepsis
93
sepsis
92
leukemia
85
melanoma
84
hepatocellular carcinoma
83
hypovitaminosis
82
ash
81
colorectal cancer
80
iron overload
79
aqueous humor
77
myocardial infarction
71
tumor growth
69
adenocarcinoma
69
heart disease
69
plaque
68
neuroblastoma
68
colon cancer
66
asthma
66
RDA
65
hypercholesterolemia
64
SEM
64
prostate cancer
62
osteoporosis
62
renal disease
61
metabolic syndrome
59
myocardial ischemia
58
dehydration
58
NAME
58
HIV
53
chronic disease
53
gastritis
50
pancreatic cancer
50
squamous cell carcinoma
49
mole
48
mole
48
infectious diseases
48
tuberculosis
47
heart failure
46
dementia
46
preeclampsia
45
iron deficiency anemia
45
arthritis
45
chronic renal failure
44
rheumatoid arthritis
43
pneumonia
43
coronary artery disease
43
MCF
43
cornea
42
AIDS
40
atrophic gastritis
39
malaria
39
more...
Symptom
acidity
167
pain
112
overweight
97
fatigue
72
diarrhea
44
anesthesia
43
seizures
41
weakness
35
starvation
32
anorexia
25
collapse
25
hyperoxia
24
angina
21
skin damage
20
exhaustion
19
cough
19
respiratory distress
17
chills
16
thinning
15
hypothermia
15
headache
14
erythema
14
vomiting
13
nausea
12
dyspnea
12
arthralgia
12
constipation
10
bone pain
9
shortness of breath
9
cyanosis
9
wheezing
9
myalgia
9
tremor
9
HSA
9
lethargy
8
agitation
8
Blanching
8
functional recovery
7
ataxia
6
Ill
6
hepatomegaly
6
chest pain
6
flushing
5
inanition
5
spasm
5
sleepiness
5
hypotonia
5
nausea and vomiting
5
dry skin
4
analgesia
4
back pain
4
discomfort
4
vertigo
4
memory loss
4
eds
4
acute stress
4
hunger
4
Anoxia
4
knee pain
4
hypercapnia
4
insomnia
4
colic
3
tingling
3
discomfort
3
abdominal pain
3
bradykinesia
3
limb pain
3
stigma
3
bitter taste
3
nasal congestion
3
apathy
3
pallor
3
Depressive symptoms
3
tinnitus
3
polydipsia
3
tachypnea
3
paraparesis
3
asthenia
3
halitosis
2
sore throat
2
more...
Drug
ascorbate
23072
vitamin E
2750
NADH
441
ROS
295
niacin
269
Vitamin E
244
lysine
192
Glutathione
156
Dermatol
96
citric acid
87
Vitamin A
83
caffeine
63
Leaf
54
FeCl3
52
Cardiovasc
52
Capsicum
43
lactose
43
FAD
37
Sodium ascorbate
37
Nitric Oxide
36
Ethanol
35
Tocopherol
34
Gel
33
pyridoxal phosphate
31
nitroglycerin
29
THF
28
Heme
28
Mutagen
26
ALA
26
CSF
24
L-tyrosine
23
Riboflavin
21
MAP
20
Nephron
19
Asn
18
CaCl2
17
CaCl2
17
Indomethacin
17
TAC
17
Vitamin B12
17
CaCl2
17
CTX
16
Vitamin K
16
Monit
16
Albumin
16
Carotenoid
16
BH4
15
Desferal
15
Fructose
15
ZnO
15
Adriamycin
15
Desferal
15
IFN-gamma
14
EE2
13
Rutin
13
Nephron
13
Dial
13
Vitamin B
13
NH3
12
Bifidobacterium
12
EPA
12
NBT
12
Spectrum
12
CoCl2
11
IL-2
11
Aloe
11
CoCl2
11
PCB
10
Methylene blue
10
ampicillin
10
HCH
10
ENT
9
CAM
9
Asthma
9
-deoxyadenosine
8
Glycyrrhiza
7
Sodium nitroprusside
7
Arsenic trioxide
7
Apomorphine
7
DPA
7
more...
Enzyme
superoxide dismutase
1985
catalase
1899
glutathione peroxidase
888
peroxidase
843
glutathione reductase
692
ascorbate peroxidase
615
dehydroascorbate reductase
304
alkaline phosphatase
279
SOR
250
xanthine oxidase
226
lactate dehydrogenase
224
glutathione S-transferase
221
alanine aminotransferase
204
aspartate aminotransferase
202
ATPase
199
ascorbate oxidase
194
cytochrome oxidase
149
ceruloplasmin
136
mitogen-activated protein kinase
121
caspase-3
120
glucose-6-phosphate dehydrogenase
116
NADPH oxidase
110
NADPH oxidase
103
tyrosinase
94
lipoxygenase
94
prolyl hydroxylase
94
creatine kinase
92
dopamine beta-hydroxylase
91
complex I
88
trypsin
81
diaphorase
80
ERK
75
succinate dehydrogenase
67
gamma-glutamyl transpeptidase
66
CPR
64
NO synthase
61
ACS
59
protein kinase
59
collagenase
59
lysozyme
57
NQO1
55
acetylcholinesterase
54
glucose oxidase
46
AST
45
protein kinase C
42
PARP
41
thrombin
41
heme oxygenase
38
guanylate cyclase
36
peroxiredoxin
35
glutamine synthetase
35
PAL
35
acid phosphatase
35
malate dehydrogenase
34
lactonase
34
GLO
34
phospholipase A2
34
isocitrate dehydrogenase
34
thioredoxin reductase
33
isocitrate dehydrogenase
32
proteasome
31
PAM
31
nitrite reductase
31
cytochrome c peroxidase
29
caspase-9
29
glyceraldehyde-3-phosphate dehydrogenase
28
phosphorylase
28
nitrate reductase
27
hydrogenase
27
hydrogenase
27
nitrate reductase
26
nitrate reductase
26
gamma-glutamylcysteine synthetase
26
nitrate reductase
26
nitrate reductase
26
tyrosine hydroxylase
26
aldose reductase
26
nitrate reductase
26
glyoxalase II
26
pepsin
25
more...
Compound
oxygen
3617
Ascorbic acid
2556
iron
2386
water
2061
sodium
1882
Dec
1603
DNA
1524
GSH
1480
GSH
1479
hydrogen
1446
calcium
1332
copper
1288
glucose
1061
H2O2
996
Clin
945
zinc
905
nitric oxide
764
phosphate
752
cysteine
648
selenium
566
potassium
540
NADPH
494
NADPH
493
nitrogen
477
salt
449
NADH
440
ATP
432
proline
399
ethanol
376
retinol
369
sulfate
364
EDTA
356
EDTA
351
acetate
342
galactose
310
vitamin D
304
Vitamin E
301
glutamate
297
ADP
293
His
293
ADP
282
ADP
281
arginine
276
nitrate
271
DPPH
263
manganese
263
cyanide
259
CO2
248
tyrosine
246
GSSG
241
lysine
237
methionine
233
MDA
225
NAD
224
Cu(II)
221
urea
217
cadmium
209
N-acetylcysteine
208
phosphorus
195
superoxide radical
191
creatinine
184
NAD
182
oxalate
182
2-oxoglutarate
181
tryptophan
181
tryptophan
178
tryptophan
176
tryptophan
176
gallic acid
166
iodine
161
phenol
155
nicotinamide
152
chromium
151
NADP
148
alanine
146
methanol
140
ammonium
139
phenazine
130
CAT
130
CAT
130
more...