Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: DrugBank:EXPT00568 (ascorbate)
 23,072 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Persons who use tables of food composition have often found that foods that vegetarians commonly eat are not included. To help remedy this situation, a table is presented which includes the 49 foods on the vegetarian Exchange Lists and 18 additional nonmeat foods. Nutrient contents of household measures of these foods are given for water, protein, fat, carbohydrate, calcium, phosphorus, iron, potassium, zinc, vitamin A, thiamin, riboflavin, niacin, vitamin C, and folacin. Nutrient amounts were derived from USDA sources and from other published research when available. Nutrient amounts from foods assumed to be identical to those in the table were placed in parentheses. When nutrient amounts were not available, they were estimated from similar foods and placed in brackets. When values found for a single nutrient in a food varied by 20% or more, the total range was shown. When a dash was found in a literature reference and the amount of the nutrient was known to be insignificant, a zero was presented in the table. Thus, there are no gaps in the table. Until accurate laboratory-derived data are available for the nutrients in vegetarian foods, this table, used with appropriate judgment, should be useful for estimating the nutrient intakes of persons who eat vegetarian foods.
 ...
PMID:Nutrients in vegetarian foods. 636 Nov 2

Between 1977 and 1979, the H.J. Heinz Company of Canada Ltd conducted a longitudinal survey of infant nutrition from birth to 18 months. In 1980, 189 of the original 403 infants were recruited in a follow-up study. The age of the children in the follow-up study was 3.5 to 4 years. This article describes the food and nutrient intakes of the preschool children. Food intake information was obtained by the 4-day dietary record method. The mean energy intake of the children was adequate to support normal growth. The mean nutrient intakes were above the recommended daily intakes of the Canadian Dietary Standard. All children ate three regular meals and at least one in-between meal snack. Milk was the primary source of energy, protein, fat, calcium, phosphorus, sodium, potassium, and riboflavin. Meat contributed a substantial amount of protein, fat, and niacin. Cereal and cereal products were the primary source of iron and were good sources of carbohydrates, sodium, and the B vitamins. Fruit and fruit juices were the primary sources of carbohydrate and vitamin C. Vitamin supplements provided large amounts of vitamin A and the B vitamins. Since foods alone included sufficient nutrients to provide the recommended daily nutrient intakes, vitamin supplements were largely unnecessary.
 ...
PMID:Dietary intakes of preschoolers. 671 51

Nutritional status indicators were assessed chemically in blood and urine taken from 625 Transkeians drawn from three age-groups in each of two regions: one with a moderate risk for esophageal cancer and one with a very high risk. Aggregate mean values for protein, albumin, vitamin A, and phosphorus were generally acceptable, but many subjects had inadequate (though not necessarily deficient) values for nicotinic acid (74% of subjects), magnesium (60%), vitamin C (55%), carotene (53%), riboflavin (41%), calcium (35%), and zinc (27%). Groups at highest risk for esophageal cancer had markedly lower serum magnesium and carotene concentrations and mildly depressed hemoglobin and hematocrit values, but such findings are not necessarily associated with esophageal cancer etiology. Possible intestinal malabsorption in the populations at highest risk may be associated with the unusually high fiber and phytate intake of the high-risk populations as well as with exposure to necrotizing mycotoxins. Thus, while protein and energy nutriture seem generally adequate, both the high- and moderate-risk populations had high incidences of multiple micronutrient malnutrition.
 ...
PMID:Nutritional status of African populations predisposed to esophageal cancer. 684 45

The relationships between systolic and diastolic blood pressure, and select demographic, dietary, life-style, and anthropometric variables were examined for a specialized sample of 10,419 adults, 18 years and over, from the National Health and Nutrition Examination Survey (NHANES) I conducted in 1971-1974. The bivariate relationships of blood pressure to each of the measurements above were examined using zero-order correlation coefficients, and Step-wise linear regression. Age and body mass index (BMI) played a major role in accounting for most of the variance in blood pressure. These two indices alone accounted for 94.5% and 89.0% of the variance in systolic and diastolic blood pressure. In contrast, only 5.5% and 11.0% of the changes in systolic and diastolic blood pressure were explained by all other variables combined. Diet explained less than 1% of the total variance observed for blood pressure for whites, and less than 5% for nonwhites. Select dietary variables such as sodium/potassium ratio, calories from fat, and % saturated fat were not significantly (p less than 0.001) correlated to blood pressure. On the other hand, food calcium, sodium/calcium ratio, food vitamin C, and calcium/phosphorus ratio were significantly correlated to both systolic and diastolic blood pressure.
 ...
PMID:Demographic, dietary, life style, and anthropometric correlates of blood pressure. 710 43

In a cross-sectional study the effects of several nutritional factors on the manifestations of osteoporosis were investigated in 23 postmenopausal women aged 50 to 70 years. Twelve women (group 1) with osteoporosis and eleven healthy control subjects (group 2) were instructed to keep a seven-day nutritional record. Body mass index (BMI) was recorded, and radiological and bone mineral density investigations were undertaken. The daily total energy, protein, fat, carbohydrate, fiber, oxalic acid, calcium, magnesium, phosphorus, sodium, fluoride, zinc, copper, manganese, vitamin C, D, and K intake were analysed within the framework of a nutritional science program. No intergroup differences were observed with regard to total energy intake, nutritional components and BMI; however, age and years since the menopause differed significantly (p < 0.05). The results suggest that the manifestation of osteoporosis in women is influenced to a greater extent by age and years since the menopause than by the distribution of nutritional factors in a normal mixed diet. However, further studies are essential to evaluate the role of dietary composition on the manifestations of osteoporosis.
 ...
PMID:[Nutrition and osteoporosis: a nutritional analysis of women in postmenopause]. 766 1

In this paper we use 24-h dietary recall data to assess the dietary effects of participation in the National School Lunch Program (NSLP) and the School Breakfast Program (SBP). After adjustment for differences in characteristics between NSLP participants and nonparticipants, NSLP participation is associated with higher lunch intakes of vitamin A, calcium, and magnesium, and a lower intake of vitamin C. Although mean intakes of other key dietary components such as food energy, iron, cholesterol, and sodium are higher for NSLP participants than for nonparticipants, these differences appear to be due to underlying differences in unobserved characteristics (eg, food preferences, appetites, or food energy needs) rather than to the NSLP. Both at lunch and over 24 h, NSLP participation is associated with consumption of a higher percentage of food energy from fat and saturated fat. SBP participation is associated with higher breakfast intakes of food energy, calcium, riboflavin, phosphorus, and magnesium, and with a higher percentage of breakfast food energy from fat and saturated fat, and a lower percentage of food energy from carbohydrate.
 ...
PMID:Dietary effects of the National School Lunch Program and the School Breakfast Program. 783 69

A population-based case-control study including 726 patients with colon cancer, 575 with rectum cancer, and 1400 population controls matched on age (+/- 5 yrs.) and sex was carried out to evaluate the association of ten inorganic elements, including potassium, sodium, calcium, magnesium, iron, manganese, zinc, copper, phosphorus and selenium, and other dietary factors with colorectal cancer. Single variable analysis adjusted for age and sex showed most of the ten elements, except sodium and selenium, may reduce the risk of the development of colorectal cancer. Correlation analysis indicated these eight elements correlated closely to the "vegetable factors", e.g., dietary fibre, and so on, since the major sources (about 80%) of these elements were from vegetables. Multi-variable logistic regression analysis showed nine elements (except sodium) may confound the effects of some dietary factors (such as dietary fibre and vitamin C) on the occurrence of colorectal cancer and only contribute to it. The results showed a close association between saturated fatty acid, mono-unsaturated fatty acid, dietary fibre, vitamins C and E, and colorectal cancer.
 ...
PMID:[Relationship between colorectal cancer and ten inorganic elements]. 813 59

The association of nutritional factors with cervical dysplasia was examined through a case-control study. Analysis was conducted in 257 cases and 133 controls confirmed both by cytological examination and colposcopic findings. A 24-h dietary recall questionnaire was used to assess nutritional intake. Various risk factors (including age at first intercourse, number of sexual partners, parity, cigarette smoking, oral contraceptive use, human papillomavirus type 16 infection, and age and race) were adjusted for their potential confounding effects. While analyses were also performed to adjust for total calories, results were not changed significantly. Among the nutrients examined, vitamin A intake showed a significantly increased risk at the lowest quartile compared to the highest quartile, with an odds ratio of 2.2 (95% confidence interval, 1.2-4.2). A significant trend of increasing risk was also observed with lower intake of vitamin A (P = 0.05). Riboflavin showed increased risk at the two lower quartiles of intake with a trend test P value of 0.04. Increased risk was also found for lower intakes of vitamin C compared to the highest intake level. For folate, increased risk was found in the second highest quartile compared with the highest quartile with an odds ratio of 2.0 (95% confidence interval, 1.0-3.8). The calcium:phosphorus ratio showed an increased risk at the lowest level (odds ratio, 2.0; 95% confidence interval, 1.0-4.3). Insufficient intake of vitamin A, riboflavin, ascorbate, and folate is associated with an increased risk of cervical dysplasia.
 ...
PMID:A case control study of nutritional factors and cervical dysplasia. 826 68

Calcium/magnesium salts of L-glutamate and L-ascorbate were tested for modification potential using a rat multiorgan carcinogenesis bioassay. Following sequential treatment with three different carcinogens (diethylnitrosamine, N-methylnitrosourea, and dihydroxydi-N-propylnitrosamine) over a 4-wk period, rats were given diet containing 5% monocalcium di-L-glutamate tetrahydrate (Ca-glutamate), 2.5% monomagnesium di-L-glutamate tetrahydrate (Mg-glutamate), 5% L-glutamic acid, 5% monocalcium di-L-ascorbate dihydrate (Ca-ascorbate), 2.5% monomagnesium di-L-ascorbate dihydrate (Mg-ascorbate), or 5% L-ascorbic acid for 16 wk. Body weight increase was slightly suppressed in the groups receiving Ca-ascorbate, Mg-ascorbate, and ascorbic acid supplementation after the carcinogen treatments. While administration of Ca-glutamate or Ca-ascorbate raised urinary pH, ascorbic acid values were decreased. Concentrations of calcium and magnesium ions in the urine increased after ingestion of Ca-glutamate or Ca-ascorbate, and Mg-glutamate or Mg-ascorbate, respectively, but phosphorus levels decreased in all groups given calcium and magnesium salts. No consistent treatment-related changes in the concentrations of sodium or potassium ions in the urine were detected. Histopathological investigation at wk 20 did not demonstrate any modification of tumorigenesis with regard to the incidence of frequency of lesions developing in the various target organs/tissues. The present results thus revealed no apparent enhancement of carcinogenesis at any site, including the urinary system, by calcium or magnesium salts using the present rat multiorgan carcinogenesis bioassay.
 ...
PMID:No enhancing effects of calcium/magnesium salts of L-glutamate and L-ascorbate on tumor development in a rat medium-term multiorgan carcinogenesis bioassay. 849 29

Differences in micronutrient intake have been observed between populations of differing socioeconomic status (SES) and ethnicity. This study reports micronutrient intake among Hispanic and non-Hispanic white (NHW) persons in the rural San Luis Valley of southern Colorado. Current diet was assessed for a geographically based sample of 552 Hispanic and 754 NHW adults 30-74 years of age in two counties of rural southern Colorado (1984-1988). Diet was assessed by 24-hour recall. NHWs reported higher mean calorie intakes than Hispanics of both genders. NHWs had greater intakes of calcium, magnesium, potassium, phosphorus, riboflavin, niacin, zinc, vitamin A, and vitamin C than Hispanics, after accounting for ethnic differences in gender, age, and calorie intake. Differences in intake by gender were observed within and between ethnic groups. After adjusting for gender, age, ethnicity, and calories, we observed no statistically significant trends by SES measures. We conclude that diets of Hispanic adults would benefit from the addition of fresh fruits, vegetables, and high-calcium foods.
 ...
PMID:Ethnic differences in micronutrient intake in a rural biethnic population. 857 59


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>