Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: DrugBank:EXPT00514 (Amiloride)
1,513 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ATPase 113
Sep 108
ENaC 84
sodium channel 80
Mol 80
ATP 54
CO2 46
collecting duct 43
insulin 42
Na+/H+ antiporter 39
proximal tubule 35
Gen 35
vasopressin 27
albumin 25
renin 24
Net 23
brush border 23
carbonic anhydrase 19
alpha, beta 19
calcium channel 19
NHE1 17
urokinase-type plasminogen activator 16
collagen 16
epidermal growth factor 15
ASIC2 15
DMA 14
angiotensin II 12
AMP 11
tumor necrosis factor 10
arginine vasopressin 10
adenosine triphosphatase 9
lipopolysaccharide 9
microsomal 9
sodium pump 9
ASIC3 9
adenosinetriphosphatase 8
PKC 8
plasminogen 8
nitric oxide synthase 7
thrombin 7
more...
Disease
cystic fibrosis 47
hypertension 45
ischemia 25
cancer 23
tumor 21
SEM 21
essential hypertension 13
depression 13
pulmonary edema 10
Luminal 10
aldosteronism 7
wasting 7
hepatocellular carcinoma 7
glioma 7
cholera 7
pertussis 6
congestive heart failure 6
diabetes 6
proteinuria 6
pH increased 5
Liddle's syndrome 5
Conn 5
Blocking 5
Hodgkin's disease 5
heart failure 5
neuroblastoma 5
cold 5
alkalosis 5
renal tubular acidosis 5
renal disease 4
cerebral ischemia 4
nephrogenic diabetes insipidus 4
erythroleukemia 4
lung disease 4
GSH 4
uterus 4
stroke 4
Bartter's syndrome 4
polycystic kidney 3
ADH 3
more...
Symptom
pain 13
hypercapnia 8
cough 5
collapse 5
polyuria 5
seizures 4
anesthesia 3
respiratory distress 3
Fluctuation 2
weakness 2
hyperoxia 2
Anoxia 2
hypothermia 2
Neuropathic pain 2
functional recovery 2
polydipsia 1
Stepping 1
exhaustion 1
starvation 1
tachypnea 1
discomfort 1
nausea 1
dyspnea 1
headache 1
thirsty 1
cachexia 1
vomiting 1
anorexia 1
myalgia 1
discomfort 1
fatigue 1
Drug
Amiloride 1513
Amiloride 1513
Ouabain 63
Bumetanide 18
Cardiovasc 16
Ringer's solution 12
Hydrochlorothiazide 11
Monensin 10
caffeine 8
citric acid 7
Indomethacin 5
Citric acid 5
lysine 5
uPA 5
Nephron 5
CaCl2 5
CaCl2 5
CaCl2 5
Forskolin 5
Angiotensin II 4
NH3 4
Dermatol 3
Theophylline 3
RbCl 3
Nephron 3
RbCl 3
Chlorothiazide 3
nitroglycerin 3
Ethanol 3
CTX 2
Albumin 2
Trifluoperazine 2
Clonidine 2
PTH 2
MAP 2
CTX 2
Guanidine 2
ICI 2
Guanidine 2
NADH 2
more...
Enzyme
ATPase 129
protein kinase C 34
renin 24
urokinase-type plasminogen activator 20
carbonic anhydrase 19
protein kinase 17
kallikrein 10
trypsin 8
plasmin 8
creatine kinase 7
thrombin 7
mitogen-activated protein kinase 7
adenylate cyclase 6
collagenase 6
tissue plasminogen activator 5
ERK 5
guanylate cyclase 5
peroxidase 5
monoamine oxidase 5
alkaline phosphatase 5
phosphodiesterase 5
DNase 4
phospholipase C 3
NO synthase 3
proteasome 3
alcohol dehydrogenase 3
lactate dehydrogenase 3
ADH 3
reverse transcriptase 3
matrix metalloproteinase 9 3
tissue kallikrein 3
myosin light chain kinase 3
hexokinase 2
CD10 2
ornithine decarboxylase 2
alpha-glucosidase 2
acid phosphatase 2
DNase II 2
elastase 2
AMP-activated protein kinase 2
more...
Compound
Amiloride 1513
sodium 978
calcium 233
potassium 181
carbonate 127
water 127
Dec 97
salt 95
aldosterone 90
Clin 84
Ouabain 63
glucose 54
ATP 54
cAMP 53
CO2 51
ammonium 47
acetate 42
hydrogen 39
DNA 38
DIDS 38
Sodium 37
SITS 29
HCO 28
Salix 27
oxygen 26
acridine 24
phosphate 23
cGMP 22
Acetazolamide 19
cyanide 17
Mg2+ 17
DMA 15
HEPES 15
guanidine 15
barium 14
nickel 14
DMA 14
chlorine 14
DMA 14
urea 13
more...