Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: DrugBank:BIOD00082 (
IL-2
)
29,198
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
IL-2
28750
cytokine
8738
IL-4
7104
IFN-gamma
5317
IL-10
5098
IL-6
4733
CD4
4574
IFN
4069
CD8
3130
TNF
2804
TNF-alpha
2210
IL-5
2060
TCR
2010
Sep
1998
interferon
1883
CD25
1740
IL-1
1636
CD28
1568
IL-2 receptor
1370
tumor necrosis factor
1337
more...
Disease
tumor
3520
cancer
2891
HIV
1041
PHA
911
melanoma
760
leukemia
705
immunodeficiency
540
tuberculosis
525
lymphoma
518
tumor growth
473
Mycobacterium
450
AIDS
417
rheumatoid arthritis
406
autoimmune disease
389
graft-versus-host disease
381
APC
375
influenza
361
metastases
361
infectious diseases
356
asthma
336
more...
Symptom
exhaustion
114
diarrhea
87
pain
85
splenomegaly
56
fatigue
45
anesthesia
32
vomiting
32
anorexia
28
nausea
28
erythema
26
headache
22
dyspnea
20
cachexia
20
cough
18
chills
18
starvation
18
hypothermia
16
acute stress
16
HSA
16
respiratory distress
15
more...
Drug
IL-2
29198
IFN-gamma
5232
CSF
1226
Dermatol
228
G-CSF
219
p75
140
IFN-beta
108
IL-1ra
86
CTX
71
lysine
66
MAP
58
IL-11
57
CTX
47
CTX
47
Asthma
45
Daclizumab
39
ROS
38
Proleukin
34
vitamin E
31
Tacrolimus
29
more...
Enzyme
mitogen-activated protein kinase
519
protein kinase C
393
APC
380
ERK
293
reverse transcriptase
280
granzyme B
280
focal adhesion kinase
268
protein kinase
223
MIP
205
calcineurin
183
superoxide dismutase
142
luciferase
119
alanine aminotransferase
105
catalase
102
caspase-3
92
peroxidase
91
aspartate aminotransferase
83
MEK
78
phospholipase C
70
phosphatidylinositol 3-kinase
69
more...
Compound
TNF
2804
Dec
2167
Clin
1808
DNA
1642
calcium
910
PMA
639
PMA
635
tyrosine
628
acetate
603
nitric oxide
343
water
269
oxygen
227
cAMP
226
sodium
196
glucose
193
leucine
186
PGE2
165
FK506
159
BCG
158
serine
157
more...