Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: DrugBank:BIOD00017 (
IFN-gamma
)
28,919
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
IFN-gamma
28915
cytokine
9633
IL-4
6995
interferon
5735
TNF-alpha
5685
IL-2
5223
IL-10
5048
CD4
3820
IL-6
3060
CD8
2999
IFN
2599
Sep
2139
IL-5
1969
LPS
1608
tumor necrosis factor
1365
TCR
1187
Cytokine
1127
MHC
1125
TGF-beta
1122
IL-1
1065
lipopolysaccharide
1023
TNF
1009
IgE
956
IL-13
946
GM-CSF
870
IL-18
849
Mol
827
MHC class II
823
IL-8
822
IFN-beta
820
chemokine
813
lymphoid
811
CD28
797
HLA
775
interferon-gamma
747
MHC class I
732
CD25
689
CD40
680
IL-1 beta
654
inducible nitric oxide synthase
645
more...
Disease
tumor
2930
cancer
2167
Mycobacterium
1146
tuberculosis
1056
HIV
907
melanoma
625
multiple sclerosis
582
infectious diseases
580
encephalomyelitis
569
asthma
540
virus infection
537
immunodeficiency
458
diabetes
454
tumor growth
445
influenza
424
autoimmune disease
411
APC
398
leishmaniasis
383
arthritis
383
malaria
375
PHA
370
AIDS
361
rheumatoid arthritis
349
carcinoma
349
Infection
337
leukemia
333
vaccinia
279
SCID
276
systemic lupus erythematosus
257
cytomegalovirus
240
eosinophilia
237
herpes simplex
235
colitis
234
lymphoma
228
hepatitis C
224
DBA
215
metastases
214
atopic dermatitis
207
type 1 diabetes
207
graft-versus-host disease
207
more...
Symptom
splenomegaly
70
diarrhea
56
pain
47
exhaustion
40
cachexia
39
fatigue
26
weakness
22
anorexia
21
starvation
20
wheezing
20
erythema
19
hypothermia
18
headache
14
respiratory distress
11
nausea
11
seizures
11
hepatosplenomegaly
11
anesthesia
10
myalgia
9
HSA
9
chills
9
cough
9
Ill
9
collapse
8
vomiting
8
acute stress
7
arthralgia
6
Welt
5
flushing
5
sneezing
5
angina
4
hyperoxia
4
abdominal pain
4
functional recovery
4
rigors
4
ataxia
4
hepatomegaly
3
microbial colonization
3
nasal discharge
3
pelvic pain
3
more...
Drug
IFN-gamma
28919
IL-2
5232
CSF
1134
IFN-beta
811
Dermatol
290
G-CSF
116
Asthma
73
lysine
65
p75
60
IL-11
48
Allergen
46
Meth
35
BCG vaccine
33
Gel
32
IL-1ra
32
MAP
30
Indomethacin
26
DNase I
26
CTX
25
ROS
25
Histamine
23
Bifidobacterium
22
Nitric Oxide
22
TAC
19
CAM
19
MRC
18
Tacrolimus
15
Imiquimod
15
vitamin E
15
Retinoic acid
15
CCL
14
ascorbate
14
CTX
13
CTX
13
Forskolin
12
KGF
12
Taxol
11
Nephron
11
PDL
11
Fraction
10
more...
Enzyme
NO synthase
442
mitogen-activated protein kinase
421
APC
404
reverse transcriptase
281
protein kinase
239
protein kinase C
231
ERK
215
granzyme B
176
MIP
160
focal adhesion kinase
160
proteasome
154
peroxidase
129
luciferase
128
indoleamine 2,3-dioxygenase
111
caspase-3
96
RNase
95
RNase
95
alanine aminotransferase
93
NOS
91
superoxide dismutase
81
catalase
77
RNA polymerase
74
caspase-1
68
trypsin
66
arginase
65
transcriptase
59
NADPH oxidase
58
beta-galactosidase
58
collagenase
57
calcineurin
57
MEK
56
NADPH oxidase
54
lysozyme
52
lactate dehydrogenase
47
aspartate aminotransferase
45
phosphodiesterase
41
caspase-8
39
neuraminidase
36
Thy1
36
TSP-1
36
more...
Compound
Dec
2288
DNA
1998
Clin
1774
nitric oxide
1179
TNF
1009
calcium
416
PMA
399
PMA
387
tyrosine
374
acetate
372
arginine
371
NKT
336
BCG
320
oxygen
307
DBA
219
DBA
215
DBA
215
sodium
209
tryptophan
193
cAMP
191
tryptophan
178
THP
176
tryptophan
174
tryptophan
174
THP
170
water
166
nitrogen
163
PGE2
159
glucose
149
sulfate
127
phosphate
120
serine
118
retinoic acid
110
PGE
107
cysteine
103
iron
100
PPD
100
SDS
99
PPD
99
lysine
92
more...