Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: DrugBank:APRD01294 (
Zoledronic acid
)
799
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
62
Mol
36
alkaline phosphatase
32
collagen
22
RANKL
18
osteocalcin
16
cytokine
15
type I collagen
14
aromatase
13
osteosarcoma
12
insulin
11
caspase-3
11
TNF
10
BMD
9
She
9
PTH
9
parathyroid hormone
9
CTX
9
osteoprotegerin
9
farnesyl diphosphate synthase
8
more...
Disease
cancer
211
osteoporosis
158
bone metastases
154
breast cancer
126
tumor
122
prostate cancer
99
multiple myeloma
83
bone disease
69
hypercalcemia
57
metastases
57
lung cancer
35
PDB
31
hypercalcemia of malignancy
27
tumor growth
27
spinal cord compression
24
metastatic breast cancer
17
carcinoma
15
renal cell carcinoma
14
influenza
13
MCF
13
more...
Symptom
pain
64
bone pain
52
nausea
7
arthralgia
7
fatigue
6
myalgia
6
vomiting
4
thigh pain
2
diarrhea
2
weakness
2
headache
2
anesthesia
2
back pain
2
constipation
2
functional recovery
2
elbow pain
1
Ill
1
Flu-like symptoms
1
anorexia
1
insomnia
1
more...
Drug
Zoledronic acid
799
Zoledronic acid
505
Denosumab
26
APD
17
Aredia
17
CTX
12
Gleevec
11
Bevacizumab
11
Teriparatide
10
CTX
9
Pegasys
9
PTH
9
CTX
9
Ibandronate
8
Clodronate
8
Gefitinib
8
Adalimumab
7
Sorafenib
7
Rosuvastatin calcium
7
Cetuximab
7
more...
Enzyme
alkaline phosphatase
32
mitogen-activated protein kinase
12
ERK
9
caspase-3
8
focal adhesion kinase
6
protein kinase
5
GSK
5
catalase
5
luciferase
4
alanine aminotransferase
4
FAST
4
superoxide dismutase
4
cathepsin K
4
3beta-hydroxysteroid dehydrogenase
3
prostate-specific antigen
3
acid phosphatase
3
PARP
3
aspartate aminotransferase
3
APC
2
sulfatase
2
more...
Compound
nitrogen
81
Clin
78
calcium
75
Dec
51
Zearalenone
34
creatinine
26
vitamin D
25
Pamidronate
23
Alendronate
21
sodium
20
MDA
19
acetate
16
Alendronate
15
phosphate
15
MTT
14
salt
14
DNA
14
water
14
PEG
14
oxygen
12
more...