Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: DrugBank:APRD01142 (Nitric Oxide)
 2,598 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
nitric oxide synthase 392
inducible nitric oxide synthase 267
Sep 183
eNOS 113
lipopolysaccharide 97
neuronal nitric oxide synthase 95
cytokine 84
hemoglobin 75
GSH 66
aquaporin-4 66
guanylate cyclase 60
endothelial nitric oxide synthase 59
TNF 51
LPS 48
soluble guanylyl cyclase 44
insulin 44
EPR 41
superoxide dismutase 41
AQP4 40
ATP 39
more...
Disease
NAME 151
cancer 90
tumor 88
hypertension 84
Neuromyelitis optica 76
ischemia 75
multiple sclerosis 68
GSH 66
diabetes 63
optic neuritis 59
myelitis 58
pulmonary hypertension 37
stroke 35
cardiovascular disease 33
atherosclerosis 30
asthma 27
heart failure 26
cerebral ischemia 21
cold 20
sepsis 19
more...
Symptom
pain 31
anesthesia 12
seizures 10
exhaustion 6
headache 6
weakness 6
diarrhea 5
hypothermia 5
HSA 5
respiratory distress 5
overweight 4
angina 4
paraparesis 4
functional recovery 4
vomiting 4
hyperoxia 4
cachexia 3
hypercapnia 3
spasticity 2
orofacial pain 2
more...
Drug
Nitric Oxide 2598
ascorbate 36
ROS 27
IFN-gamma 22
nitroglycerin 16
Heme 14
lysine 13
Glutathione 11
BH4 11
CSF 10
Sodium nitroprusside 10
Aminoguanidine 10
Angiotensin II 9
Asthma 8
Rituximab 8
MAP 8
NADH 8
Indomethacin 6
IL-2 5
Cardiovasc 4
more...
Enzyme
NO synthase 208
NOS 160
guanylate cyclase 81
superoxide dismutase 59
mitogen-activated protein kinase 53
protein kinase 49
catalase 41
peroxidase 37
arginase 26
xanthine oxidase 25
NADPH oxidase 23
NADPH oxidase 22
ERK 22
NADPH-diaphorase 21
nitrate reductase 21
nitrate reductase 21
phosphodiesterase 21
nitrate reductase 21
nitrate reductase 21
nitrate reductase 21
more...
Compound
nitric oxide 1232
arginine 307
oxygen 267
nitrate 235
Dec 192
nitrogen 176
sodium 157
cGMP 146
water 125
DNA 101
cysteine 100
iron 98
H2S 85
calcium 82
tyrosine 70
GSH 69
GSH 69
glucose 60
Nitrite 60
Nitrite 55
more...