Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: DrugBank:APRD00951 (Erlotinib)
 749 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
epidermal growth factor receptor 381
tyrosine kinase 348
EGFR 177
EGF receptor 57
Epidermal growth factor receptor 51
Sep 45
Mol 36
HER2 31
AKT 25
vascular endothelial growth factor 23
epidermal growth factor 22
EGF 21
receptor tyrosine kinase 20
ATP 20
mTOR 17
ERK 15
ERK1 14
PI3K 13
MAPK 13
Tyrosine kinase 11
more...
Disease
cancer 277
lung cancer 227
non-small cell lung cancer 220
tumor 173
rash 94
adenocarcinoma 73
pancreatic cancer 63
lung carcinoma 55
tumor growth 41
breast cancer 33
squamous cell carcinoma 30
metastases 28
tumorigenesis 21
carcinoma 21
interstitial lung disease 17
tumor progression 15
brain metastases 15
MCF 14
colorectal cancer 14
glioma 13
more...
Symptom
diarrhea 66
fatigue 19
nausea 11
dyspnea 6
cough 6
anorexia 5
pain 4
asthenia 3
vomiting 3
decreased appetite 2
shortness of breath 2
nausea and vomiting 2
dry skin 2
hemoptysis 2
lethargy 1
headache 1
flushing 1
back pain 1
erythema 1
hypothermia 1
more...
Drug
Erlotinib 749
Tarceva 196
Gefitinib 141
Cetuximab 51
Bevacizumab 35
Herceptin 21
Imatinib 19
Gleevec 16
Docetaxel 14
Sorafenib 13
Pemetrexed 13
Dermatol 11
GEO 10
Tykerb 7
Gemzar 7
Panitumumab 6
Pertuzumab 5
Alimta 5
Everolimus 4
Dasatinib 4
more...
Enzyme
ERK 213
mitogen-activated protein kinase 40
focal adhesion kinase 18
protein kinase 14
CYP3A4 9
caspase-3 9
MEK 7
PARP 4
phosphoinositide 3-kinase 4
luciferase 4
catalase 4
P-glycoprotein 3
thymidylate synthase 3
AMP-activated protein kinase 3
proteasome 3
urokinase-type plasminogen activator 2
peroxidase 2
caspase-9 2
NADPH oxidase 2
thymidine phosphorylase 2
more...
Compound
Clin 56
Dec 53
tyrosine 42
DNA 21
ATP 20
quinazoline 15
quinazoline 15
water 13
Docetaxel 12
oxygen 11
MTT 11
methionine 10
Tyrosine 10
Gemcitabine 9
Gemcitabine 9
HCl 9
MDA 9
DDP 7
acetonitrile 6
acetate 6
more...