Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: DrugBank:APRD00729 (Parkin)
 1,867 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Parkin 1863
PINK1 586
ubiquitin 374
parkin 359
E3 ubiquitin ligase 235
Mol 222
PTEN 184
proteasome 155
PARK2 141
DJ-1 138
LC3 134
ubiquitin ligase 127
p62 116
alpha-synuclein 108
Sep 98
LRRK2 94
synuclein 84
ATP 82
endoplasmic reticulum 75
PARKIN 64
more...
Disease
Parkinson's disease 914
parkinsonism 278
PARK2 141
cancer 108
Alzheimer's disease 78
tumor 69
ischemia 42
neuroblastoma 38
dementia 32
PARK6 32
movement disorder 30
amyotrophic lateral sclerosis 26
diabetes 22
tumorigenesis 22
OPA1 20
lung cancer 18
GSH 15
type 2 diabetes 15
depression 14
hepatocellular carcinoma 13
more...
Symptom
starvation 21
tremor 17
dystonia 13
collapse 13
bradykinesia 7
ataxia 5
weakness 5
seizures 4
pain 4
cachexia 3
fatigue 3
functional recovery 3
memory loss 3
hyperoxia 3
respiratory distress 2
myoclonus 2
dysarthria 2
hypothermia 2
diarrhea 1
Dribbling 1
more...
Drug
Parkin 1867
Parkin 1863
ROS 45
lysine 22
Monit 6
Cardiovasc 4
RFP 3
Nitric Oxide 2
Madopar 2
TAT 2
NADH 2
Alliance 2
Liraglutide 2
ADM 2
Heme 2
3-Methyladenine 2
OTC 1
Florfenicol 1
CFT 1
TAK 1
more...
Enzyme
proteasome 155
protein kinase 56
AMP-activated protein kinase 44
ubiquitin-protein ligase 43
complex I 42
mitogen-activated protein kinase 32
AMPK 29
AMPK 28
caspase-3 23
superoxide dismutase 22
tyrosine hydroxylase 20
ATPase 16
MPP 16
calcineurin 14
glucocerebrosidase 10
nucleoside hydrolase 10
luciferase 10
catalase 9
Omi/HtrA2 9
IKK 9
more...
Compound
oxygen 190
Dec 126
DNA 119
ATP 82
glucose 48
calcium 40
MPTP 37
cyanide 36
cysteine 31
lysine 29
serine 29
Clin 25
CCP 25
threonine 22
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 22
hydrogen 22
Ubiquitin 21
TNF 20
iron 20
zinc 18
more...