Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: DrugBank:APRD00691 (EE2)
 7,802 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
estrogen receptor 717
Sep 535
Mol 369
aromatase 247
FSH 243
insulin 199
prolactin 193
progesterone receptor 140
Gen 120
LHRH 118
follicle-stimulating hormone 113
estrogen receptor alpha 88
collagen 80
Aromatase 73
sex hormone-binding globulin 71
cytochrome P450 70
RIN 68
growth hormone 65
microsomal 61
chorionic gonadotropin 61
more...
Disease
breast cancer 369
cancer 309
tumor 268
uterus 260
MCF 186
hepatitis C 172
Steroids 108
carcinoma 73
depression 73
hypertension 71
amenorrhea 70
osteoporosis 70
carcinogenesis 65
acne 63
hepatitis 59
infertility 58
obesity 55
hepatitis B 51
ischemia 50
endometrial cancer 49
more...
Symptom
headache 71
nausea 69
pain 66
masculinization 25
vomiting 22
fatigue 22
anesthesia 21
Ill 20
discomfort 17
seizures 17
abdominal pain 16
irregular bleeding 16
nausea and vomiting 15
mastalgia 14
discomfort 14
pelvic pain 14
analgesia 13
hot flashes 12
hot flushes 10
dizziness 10
more...
Drug
EE2 7802
ENT 1548
MAP 340
Norplant 318
ICI 165
Estrogens 112
Levonorgestrel 107
Encore 107
Ovulen 40
Estriol 30
Depo-Provera 25
Dermatol 23
Ortho Tri-Cyclen 23
Monit 22
DMAP 22
caffeine 21
Luteinizing 19
Dihydrotestosterone 18
Mircette 18
Spectrum 17
more...
Enzyme
mitogen-activated protein kinase 94
ERK 75
protein kinase 70
peroxidase 57
alanine aminotransferase 48
luciferase 48
alkaline phosphatase 46
protein kinase C 40
catalase 31
superoxide dismutase 31
caspase-3 31
thromboplastin 27
HSD 26
RNase 25
RNase 25
adenylate cyclase 24
focal adhesion kinase 24
renin 22
ATPase 21
sulfatase 20
more...
Compound
Estradiol 4541
Estrogen 706
water 701
Dec 573
Clin 482
Progesterone 319
DNA 316
Estrogen 261
acetate 210
calcium 184
Testosterone 176
Testosterone 174
ICI 165
sulfate 157
glucose 154
sodium 116
oxygen 111
Abbott 97
cAMP 79
phosphate 74
more...