Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: DrugBank:APRD00568 (Cimetidine)
 1,659 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 91
cytochrome P-450 69
microsomal 65
gastrin 54
cytochrome P450 33
histamine H2 receptor 32
prolactin 25
insulin 16
albumin 14
cytochrome 14
secretin 14
Mol 13
AMP 12
adenylate cyclase 12
proximal tubule 12
mast cell 12
P450 12
TRH 12
ATPase 11
glycoprotein 10
more...
Disease
duodenal ulcer 121
peptic ulcer 71
gastric ulcer 64
cancer 47
tumor 33
esophagitis 22
Zollinger-Ellison syndrome 21
gastritis 19
SEM 17
cold 17
depression 16
cirrhosis 15
gastric cancer 15
sepsis 15
gastroesophageal reflux disease 15
sepsis 14
gynecomastia 11
cystic fibrosis 10
pneumonia 10
reflux esophagitis 10
more...
Symptom
acidity 48
pain 39
anesthesia 33
diarrhea 14
heartburn 11
hypothermia 8
headache 7
Welt 7
seizures 7
nausea 6
abdominal pain 5
dizziness 4
sleepiness 4
vomiting 4
analgesia 4
discomfort 3
angina 3
constipation 3
flushing 3
agitation 3
more...
Drug
Cimetidine 1659
Cimetidine 1607
Histamine 113
Ranitidine 83
Gastro 25
Diphenhydramine 21
Omeprazole 20
Atropine 18
Indomethacin 17
caffeine 12
Sucralfate 11
Theophylline 10
Dermatol 10
Maalox 9
Misoprostol 9
Cardiovasc 7
Gefarnate 6
IL-2 5
Tiotidine 4
Dial 4
more...
Enzyme
pepsin 34
ATPase 13
demethylase 12
adenylate cyclase 12
alcohol dehydrogenase 8
catalase 7
trypsin 7
peroxidase 7
CYP3A4 7
alkaline phosphatase 7
P-glycoprotein 6
acetylcholinesterase 6
glutathione S-transferase 6
lipoxygenase 5
lipase 4
caspase-3 4
aldehyde dehydrogenase 4
xanthine oxidase 4
histidine decarboxylase 4
protein kinase 4
more...
Compound
Clin 261
Histamine 113
Dec 96
Ranitidine 79
water 64
sodium 61
ethanol 57
calcium 49
creatinine 42
oxygen 29
HCl 27
Mepyramine 25
glucose 23
hydrogen 23
methylhistamine 23
PGE2 21
DNA 21
Omeprazole 21
Diphenhydramine 19
cAMP 18
more...