DrugBank:APRD00546 - FACTA Search

Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: DrugBank:APRD00546 (Rosuvastatin)
453 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

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Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein
C-reactive protein	60
HMG-CoA reductase	57
reductase	45
HDL	32
Sep	30
Mol	16
CRP	16
cytochrome P450	16
insulin	15
apolipoprotein B	14
ATP	14
apolipoprotein	13
endothelial nitric oxide synthase	12
LDL receptor	11
creatine kinase	11
caspase-3	9
OATP1B1	9
CYP2C9	8
nitric oxide synthase	8
polypeptide	8
breast cancer resistance protein	7
ABCG2	7
A-I	7
hemoglobin	6
organic anion transporting polypeptide	6
superoxide dismutase	6
cytokine	6
OATP1B3	6
tumor necrosis factor	5
CYP3A4	5
SLCO1B1	5
apoE	5
collagen	5
alanine aminotransferase	5
vascular endothelial growth factor	5
vascular endothelium	4
OATP2B1	4
epididymal	4
natriuretic peptide	4
BCRP	4
extracellular signal-regulated kinase	4
ERK	4
Rho	4
ERK1	4
fibronectin	4
apolipoprotein A-I	4
albumin	4
interleukin-6	4
catalase	4
NADPH	3
myeloperoxidase	3
TNF	3
ABCB1	3
AST	3
c-kit	3
A-1	3
alkaline phosphatase	3
apoB-100	3
Bcl-2	3
renin	3
matrix metalloproteinase	3
apolipoprotein E	3
p38	3
RhoA	3
myoglobin	3
ANOVA	3
MEK	3
lectin	3
glutathione peroxidase	3
cytochrome	3
Pol	3
GSH	3
CYP2C19	3
interleukin 6	2
IL-6	2
NAD	2
OAT3	2
BMP-2	2
osteogenic	2
solute carrier	2

Disease
atherosclerosis	69
cardiovascular disease	51
dyslipidemia	48
diabetes	46
hypercholesterolemia	45
coronary heart disease	33
myocardial infarction	30
hypertension	28
hyperlipidemia	26
stroke	25
heart failure	20
coronary artery disease	19
metabolic syndrome	18
myopathy	17
ischemia	16
obesity	16
proteinuria	13
plaque	13
myocardial ischemia	9
type 2 diabetes	9
cancer	8
renal failure	8
unstable angina	8
renal disease	8
HIV	7
vascular disease	6
NAME	6
aortic stenosis	6
Alzheimer's disease	5
cognitive impairment	4
AIDS	4
tumor	4
infectious diseases	4
congestive heart failure	4
ventricular hypertrophy	4
immunodeficiency	3
acute renal failure	3
cerebral ischemia	3
Endothelial dysfunction	3
GSH	3
coronary occlusion	2
aggression	2
atherosclerotic cardiovascular disease	2
delayed puberty	2
epididymis	2
hepatitis	2
Infection	2
renal insufficiency	2
renal impairment	2
Familial hypercholesterolemia	2
carcinogenesis	2
alcoholic fatty liver	2
neuropathy	2
SEM	1
arteriopathy	1
hypertensive heart disease	1
drug withdrawal	1
colitis	1
myositis	1
T-cell lymphoma	1
squamous cell carcinoma	1
Acute coronary syndrome	1
memory impairment	1
microalbuminuria	1
NOD	1
ischemic colitis	1
pancreatitis	1
prostate cancer	1
dementia	1
leishmaniasis	1
IMT	1
hepatocellular carcinoma	1
brain edema	1
Simpson-Golabi-Behmel syndrome	1
lung carcinoma	1
deep vein thrombosis	1
incontinence	1
tuberculosis	1
periodontal disease	1
MPE	1

Enzyme
3-hydroxy-3-methylglutaryl coenzyme A reductase	25
creatine kinase	15
mitogen-activated protein kinase	12
alanine aminotransferase	11
caspase-3	9
superoxide dismutase	7
3-hydroxy-3-methylglutaryl-CoA reductase	5
CYP3A4	5
NO synthase	5
ERK	5
catalase	4
NADPH oxidase	4
protein kinase C	3
aspartate aminotransferase	3
AST	3
glutathione peroxidase	3
peroxidase	3
NOS	3
reverse transcriptase	3
MEK	3
renin	3
NADPH oxidase	3
alkaline phosphatase	3
protein kinase	2
CPT	2
CPT	2
CAD	2
CPT	2
CAD	2
CAD	2
lactate dehydrogenase	2
luciferase	2
phospholipase A2	1
xanthine oxidase	1
calcineurin	1
PAT	1
collagenase	1
ACS	1
MEKK1	1
glutathione S-transferase	1
IOR	1
cholesterol acyltransferase	1
AMP-activated protein kinase	1
PAH	1
lanosterol 14alpha-demethylase	1
SMP	1
deoxyribose-5-phosphate aldolase	1
glutathione reductase	1
CPR	1
gamma-glutamylcysteine synthetase	1
firefly luciferase	1
heme oxygenase	1
lipoprotein lipase	1
HIV-1 protease	1
P-glycoprotein	1
tissue plasminogen activator	1