Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: DrugBank:APRD00546 (
Rosuvastatin
)
453
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
C-reactive protein
60
HMG-CoA reductase
57
reductase
45
HDL
32
Sep
30
CRP
16
Mol
16
cytochrome P450
16
insulin
15
apolipoprotein B
14
ATP
14
apolipoprotein
13
endothelial nitric oxide synthase
12
LDL receptor
11
creatine kinase
11
caspase-3
9
OATP1B1
9
polypeptide
8
CYP2C9
8
nitric oxide synthase
8
ABCG2
7
A-I
7
breast cancer resistance protein
7
hemoglobin
6
cytokine
6
organic anion transporting polypeptide
6
OATP1B3
6
superoxide dismutase
6
CYP3A4
5
apoE
5
tumor necrosis factor
5
alanine aminotransferase
5
SLCO1B1
5
collagen
5
vascular endothelial growth factor
5
fibronectin
4
OATP2B1
4
interleukin-6
4
albumin
4
BCRP
4
more...
Disease
atherosclerosis
69
cardiovascular disease
51
dyslipidemia
48
diabetes
46
hypercholesterolemia
45
coronary heart disease
33
myocardial infarction
30
hypertension
28
hyperlipidemia
26
stroke
25
heart failure
20
coronary artery disease
19
metabolic syndrome
18
myopathy
17
obesity
16
ischemia
16
proteinuria
13
plaque
13
myocardial ischemia
9
type 2 diabetes
9
cancer
8
renal failure
8
unstable angina
8
renal disease
8
HIV
7
NAME
6
aortic stenosis
6
vascular disease
6
Alzheimer's disease
5
cognitive impairment
4
ventricular hypertrophy
4
AIDS
4
infectious diseases
4
tumor
4
congestive heart failure
4
immunodeficiency
3
Endothelial dysfunction
3
cerebral ischemia
3
acute renal failure
3
GSH
3
more...
Symptom
myalgia
9
anesthesia
3
weakness
3
asthenia
3
nausea
2
constipation
2
dyspnea
2
angina
2
vomiting
2
abdominal pain
2
fatigue
1
overweight
1
insomnia
1
arthralgia
1
starvation
1
diarrhea
1
functional recovery
1
pain
1
Drug
Rosuvastatin
453
Cardiovasc
30
Rosuvastatin calcium
28
Simvastatin
13
niacin
9
Ezetimibe
7
Pravastatin
6
Lovastatin
5
Lipitor
3
Lipitor
3
caffeine
3
Lipitor
3
Fructose
2
Plavix
1
Poloxamer
1
Clopidogrel
1
C20H26O3
1
Darbepoetin alfa
1
Efalizumab
1
Efalizumab
1
Levitra
1
Cubicin
1
Alfuzosin
1
Elvitegravir
1
nitroglycerin
1
Acyclovir
1
Lescol
1
Febuxostat
1
Angiotensin II
1
Alfuzosin hydrochloride
1
Monit
1
Epoetin
1
Ditropan
1
CPR
1
Omalizumab
1
Vardenafil
1
ZnO
1
SMP
1
Gelatin
1
Encore
1
more...
Enzyme
3-hydroxy-3-methylglutaryl coenzyme A reductase
25
creatine kinase
15
mitogen-activated protein kinase
12
alanine aminotransferase
11
caspase-3
9
superoxide dismutase
7
ERK
5
NO synthase
5
CYP3A4
5
3-hydroxy-3-methylglutaryl-CoA reductase
5
NADPH oxidase
4
catalase
4
MEK
3
protein kinase C
3
aspartate aminotransferase
3
NOS
3
glutathione peroxidase
3
peroxidase
3
renin
3
AST
3
NADPH oxidase
3
reverse transcriptase
3
alkaline phosphatase
3
protein kinase
2
CPT
2
CPT
2
CAD
2
CPT
2
CAD
2
CAD
2
lactate dehydrogenase
2
luciferase
2
phospholipase A2
1
xanthine oxidase
1
calcineurin
1
PAT
1
collagenase
1
ACS
1
MEKK1
1
IOR
1
more...
Compound
Cardiol
55
Clin
44
Dec
33
Cholesterol
32
ATP
14
glucose
14
Atorvastatin
14
nitric oxide
13
calcium
12
oxygen
12
Statin
11
water
11
creatinine
11
DNA
9
HMG-CoA
8
arginine
7
Pravastatin
6
sodium
5
Ascorbic acid
5
MTT
4
salt
4
sulfate
4
phosphate
4
urea
3
Cerivastatin
3
TNF
3
caffeine
3
Diabetol
3
GSH
3
GSH
3
superoxide radical
3
Pluronic
3
MEK
3
NADPH
3
NADPH
3
hydroxide
3
Fluvastatin
3
Lovastatin
3
homocysteine
3
tyrosine
2
more...