Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: DrugBank:APRD00546 (Rosuvastatin)
453 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
C-reactive protein 60
HMG-CoA reductase 57
reductase 45
HDL 32
Sep 30
CRP 16
Mol 16
cytochrome P450 16
insulin 15
apolipoprotein B 14
ATP 14
apolipoprotein 13
endothelial nitric oxide synthase 12
LDL receptor 11
creatine kinase 11
caspase-3 9
OATP1B1 9
polypeptide 8
CYP2C9 8
nitric oxide synthase 8
ABCG2 7
A-I 7
breast cancer resistance protein 7
hemoglobin 6
cytokine 6
organic anion transporting polypeptide 6
OATP1B3 6
superoxide dismutase 6
CYP3A4 5
apoE 5
tumor necrosis factor 5
alanine aminotransferase 5
SLCO1B1 5
collagen 5
vascular endothelial growth factor 5
fibronectin 4
OATP2B1 4
interleukin-6 4
albumin 4
BCRP 4
more...
Disease
atherosclerosis 69
cardiovascular disease 51
dyslipidemia 48
diabetes 46
hypercholesterolemia 45
coronary heart disease 33
myocardial infarction 30
hypertension 28
hyperlipidemia 26
stroke 25
heart failure 20
coronary artery disease 19
metabolic syndrome 18
myopathy 17
obesity 16
ischemia 16
proteinuria 13
plaque 13
myocardial ischemia 9
type 2 diabetes 9
cancer 8
renal failure 8
unstable angina 8
renal disease 8
HIV 7
NAME 6
aortic stenosis 6
vascular disease 6
Alzheimer's disease 5
cognitive impairment 4
ventricular hypertrophy 4
AIDS 4
infectious diseases 4
tumor 4
congestive heart failure 4
immunodeficiency 3
Endothelial dysfunction 3
cerebral ischemia 3
acute renal failure 3
GSH 3
more...
Symptom
myalgia 9
anesthesia 3
weakness 3
asthenia 3
nausea 2
constipation 2
dyspnea 2
angina 2
vomiting 2
abdominal pain 2
fatigue 1
overweight 1
insomnia 1
arthralgia 1
starvation 1
diarrhea 1
functional recovery 1
pain 1
Drug
Rosuvastatin 453
Cardiovasc 30
Rosuvastatin calcium 28
Simvastatin 13
niacin 9
Ezetimibe 7
Pravastatin 6
Lovastatin 5
Lipitor 3
Lipitor 3
caffeine 3
Lipitor 3
Fructose 2
Plavix 1
Poloxamer 1
Clopidogrel 1
C20H26O3 1
Darbepoetin alfa 1
Efalizumab 1
Efalizumab 1
Levitra 1
Cubicin 1
Alfuzosin 1
Elvitegravir 1
nitroglycerin 1
Acyclovir 1
Lescol 1
Febuxostat 1
Angiotensin II 1
Alfuzosin hydrochloride 1
Monit 1
Epoetin 1
Ditropan 1
CPR 1
Omalizumab 1
Vardenafil 1
ZnO 1
SMP 1
Gelatin 1
Encore 1
more...
Enzyme
3-hydroxy-3-methylglutaryl coenzyme A reductase 25
creatine kinase 15
mitogen-activated protein kinase 12
alanine aminotransferase 11
caspase-3 9
superoxide dismutase 7
ERK 5
NO synthase 5
CYP3A4 5
3-hydroxy-3-methylglutaryl-CoA reductase 5
NADPH oxidase 4
catalase 4
MEK 3
protein kinase C 3
aspartate aminotransferase 3
NOS 3
glutathione peroxidase 3
peroxidase 3
renin 3
AST 3
NADPH oxidase 3
reverse transcriptase 3
alkaline phosphatase 3
protein kinase 2
CPT 2
CPT 2
CAD 2
CPT 2
CAD 2
CAD 2
lactate dehydrogenase 2
luciferase 2
phospholipase A2 1
xanthine oxidase 1
calcineurin 1
PAT 1
collagenase 1
ACS 1
MEKK1 1
IOR 1
more...
Compound
Cardiol 55
Clin 44
Dec 33
Cholesterol 32
ATP 14
glucose 14
Atorvastatin 14
nitric oxide 13
calcium 12
oxygen 12
Statin 11
water 11
creatinine 11
DNA 9
HMG-CoA 8
arginine 7
Pravastatin 6
sodium 5
Ascorbic acid 5
MTT 4
salt 4
sulfate 4
phosphate 4
urea 3
Cerivastatin 3
TNF 3
caffeine 3
Diabetol 3
GSH 3
GSH 3
superoxide radical 3
Pluronic 3
MEK 3
NADPH 3
NADPH 3
hydroxide 3
Fluvastatin 3
Lovastatin 3
homocysteine 3
tyrosine 2
more...